CN102711466A - 桥连杂环化合物及其使用方法 - Google Patents

桥连杂环化合物及其使用方法 Download PDF

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Publication number
CN102711466A
CN102711466A CN2010800528008A CN201080052800A CN102711466A CN 102711466 A CN102711466 A CN 102711466A CN 2010800528008 A CN2010800528008 A CN 2010800528008A CN 201080052800 A CN201080052800 A CN 201080052800A CN 102711466 A CN102711466 A CN 102711466A
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substituted
unsubstituted
alkyl
formula
alkoxy
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Chinese (zh)
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R·P·贾殷
S·查克拉瓦蒂
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Medivation Technologies LLC
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Medivation Technologies LLC
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN2010800528008A 2009-09-23 2010-09-23 桥连杂环化合物及其使用方法 Pending CN102711466A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24515109P 2009-09-23 2009-09-23
US61/245,151 2009-09-23
PCT/US2010/050081 WO2011038164A1 (en) 2009-09-23 2010-09-23 Bridged heterocyclic compounds and methods of use

Publications (1)

Publication Number Publication Date
CN102711466A true CN102711466A (zh) 2012-10-03

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CN2010800528008A Pending CN102711466A (zh) 2009-09-23 2010-09-23 桥连杂环化合物及其使用方法

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US (2) US9006234B2 (enExample)
EP (1) EP2480081A4 (enExample)
JP (1) JP5869484B2 (enExample)
CN (1) CN102711466A (enExample)
AU (1) AU2010298169B2 (enExample)
BR (1) BR112012006648A2 (enExample)
CA (1) CA2775216A1 (enExample)
WO (1) WO2011038164A1 (enExample)

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JP2013505948A (ja) 2013-02-21
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CA2775216A1 (en) 2011-03-31
WO2011038164A1 (en) 2011-03-31
US9006234B2 (en) 2015-04-14
EP2480081A4 (en) 2013-03-06
AU2010298169B2 (en) 2015-10-29
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US20130172366A1 (en) 2013-07-04
AU2010298169A1 (en) 2012-04-19

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