CN102698143B - Red/white peony root Chinese medicinal oral liquid for treating chronic hepatitis and preparation method - Google Patents
Red/white peony root Chinese medicinal oral liquid for treating chronic hepatitis and preparation method Download PDFInfo
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Abstract
The invention discloses red/white peony root Chinese medicinal oral liquid for treating chronic hepatitis. The oral liquid is prepared from the following raw Chinese medicaments in part by weight: 200 to 300 parts of red/white peony root, 60 to 150 parts of nutgrass galingale rhizome, 60 to 150 parts of green tangerine peel, 60 to 150 parts of kansui root, 60 to 150 parts of Baikal skullcap root, 60 to 150 parts of orange peel, and 100 to 200 parts of malt. The medicaments have the effects of soothing liver and relieving depression, regulating qi-flowing for eliminating phlegm, clearing heat and promoting diuresis; and the oral liquid is used for eliminating symptoms of stress pain, abdominal distension, decreased food intake, strength lack and pale tongue with whitish fur in liver stagnation, plays a role in supporting healthy energy without leaving pathogenic factor and eliminating the pathogenic factor without damaging healthy energy, and is low in cost and worthy of clinical popularization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine product, relate in particular to a kind of red Radix Paeoniae Alba Chinese medicine oral liquid of chronic hepatitis and preparation method thereof that is used for the treatment of.
Background technology
Chronic hepatitis refers to and caused by different pathogeny, and the course of disease at least continues to surpass hepatic necrosis and the inflammation more than 6 months, can have clinically corresponding symptom, sign regulating liver-QI biochemical analysis abnormal, also can, without obvious clinical symptoms, necrosis and the inflammation of hepatic tissue only be arranged.The course of disease is undulatory property or continues carrying out property, and if do not carried out suitable treatment, some patients were can make progress as liver cirrhosis.Chronic hepatitis is light, moderate: the early symptom of typical chronic hepatitis is slight and lack specificity, is the undulatory property intermittence, even for many years without any symptom.Modal is exactly easy fatigue and stomach discomfort, easily is left in the basket, and also easily being mistaken as is gastropathy, often see clinically invisible liver cirrhosis patient, before liver cirrhosis occurring, do not feel significant discomfort, also do not carry out conventional health check-up, progressively develop into liver cirrhosis unconsciously, occasionally there is the patient to occur feeling sick, abdominal distention, jaundice, the urine color is dark, but can not judge the order of severity of chronic hepatitis according to symptom, severely chronic hepatitis and chronic severe hepatitis: when the intensification of carrying out property of Urinary color, the intensification of carrying out property of skin yellow sclera, when weak appetite descends more and more obviously, sb.'s illness took a turn for the worse in prompting, especially need the generation of vigilant chronic severe hepatitis, chronic severe hepatitis is the performance of liver failure, can show as highly weak, height abdominal distention, height jaundice and height inappetence, hypoproteinemia can appear, ascites breast water, abdominal cavity infection, coagulation function descends, upper gastrointestinal hemorrhage, hepatic encephalopathy etc., mortality rate is higher clinically, need actively treatment.It is that side effect is large that there is disadvantage in the medication of western medicine chronic hepatitis disease, the patient is had to very large injury, and traditional Chinese medical science Chinese herbal medicine oneself by universally acknowledged be the precious treasure-houses of indispensable mankind medicine, it is gentle that Chinese medicine has the property of medicine, the characteristics such as applicable Fan Guang, as chronic hepatitis disease treatment aspect, its original effect being arranged, adopt the means of Chinese medicine to treat the chronic hepatitis disease, is a channel extremely leaved for development.
Summary of the invention
The purpose of this invention is to provide a kind of curative effect lasting, and no side effects, the red Radix Paeoniae Alba Chinese medicine oral liquid of the treatment chronic hepatitis that cost is low and preparation method.
For achieving the above object, the present invention is achieved by the following technical solutions:
Technical scheme of the present invention is: treatment chronic hepatitis red Radix Paeoniae Alba Chinese medicine oral liquid is that the raw material of Chinese medicine by following weight portion is prepared from:
Red Radix Paeoniae Alba 200-300 part, Rhizoma Cyperi 60-150 part, Pericarpium Citri Reticulatae Viride 60-150 part, Radix Kansui 60-150 part, Radix Scutellariae 60-150 part, Pericarpium Citri tangerinae 60-150 part, Fructus Hordei Germinatus 100-200 part.
The red Radix Paeoniae Alba Chinese medicine oral liquid of described treatment chronic hepatitis is that the raw material of Chinese medicine by following weight portion is prepared from:
300 parts of the red Radix Paeoniae Albas, 150 parts of Rhizoma Cyperis, 150 parts, Pericarpium Citri Reticulatae Viride, 150 parts of Radix Kansuis, 150 parts of Radix Scutellariaes, 150 parts of Pericarpium Citri tangerinaes, 200 parts, Fructus Hordei Germinatus.
The preparation method of the red Radix Paeoniae Alba Chinese medicine oral liquid of described treatment chronic hepatitis, concrete steps are as follows
Get 300 parts of the red Radix Paeoniae Albas, 150 parts of Rhizoma Cyperis, 150 parts, Pericarpium Citri Reticulatae Viride, 150 parts of Radix Kansuis, 150 parts of Radix Scutellariaes, 150 parts of Pericarpium Citri tangerinaes, 200 parts, Fructus Hordei Germinatus, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed at 60-65 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, obtain.
Usage and consumption: oral, each 20 milliliters of medicine of the present invention, every day 3 times, half an hour, 3 months be a course for the treatment of after meal.
In raw material of Chinese medicine of the present invention, the red Radix Paeoniae Alba: bitter, be slightly cold, return Liver Channel, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, pain relieving; Rhizoma Cyperi: hot, micro-hardship, micro-sweet, flat, return liver, tri-jiao channel, depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving; Pericarpium Citri Reticulatae Viride: bitter, hot, warm, enter liver, gallbladder, stomach warp, soothing the liver dispelling the stagnated QI, removing food stagnancyization are stagnant; Radix Kansui: bitter, sweet, cold, poisonous, return lung, kidney, large intestine channel, removing fluid-retention by purgation, dispersing swelling and dissipating binds; Radix Scutellariae: bitter, cold, return lung, gallbladder, stomach, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive; Pericarpium Citri tangerinae: hot, warm, enter spleen, lung meridian, in regulating the flow of vital energy, adjusting, dampness, reduce phlegm, control distension and fullness of the chest and abdomen, anorexia, vomiting hiccup, cough with copious phlegm; Fructus Hordei Germinatus: flat, sweet, return spleen channel, stomach warp, Liver Channel, promoting digestion and invigorating the stomach, galactopoiesis relieving distension; All medicines are the merit of long memorial liver resolving depression, activating QI to eliminate phlegm, clearing away heat-damp and promoting diuresis altogether, Chinese medicine oral liquid of the present invention is eliminated the symptom of side of body pain that liver silt type has, abdominal distention, decreased food intake, weak, white and thin fur, play the not stagnant heresy of righting, eliminating evilly do not hinder positive effect, cost is low, and clinic is applied.
The specific embodiment
Embodiment 1:
Raw material of Chinese medicine: 300 parts of the red Radix Paeoniae Albas, 150 parts of Rhizoma Cyperis, 150 parts, Pericarpium Citri Reticulatae Viride, 150 parts of Radix Kansuis, 150 parts of Radix Scutellariaes, 150 parts of Pericarpium Citri tangerinaes, 200 parts, Fructus Hordei Germinatus.
Method for making: get 300 parts of the red Radix Paeoniae Albas, 150 parts of Rhizoma Cyperis, 150 parts, Pericarpium Citri Reticulatae Viride, 150 parts of Radix Kansuis, 150 parts of Radix Scutellariaes, 150 parts of Pericarpium Citri tangerinaes, 200 parts, Fructus Hordei Germinatus, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed at 60-65 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, obtain.
Embodiment 2:
Raw material of Chinese medicine: 250 parts of the red Radix Paeoniae Albas, 105 parts of Rhizoma Cyperis, 105 parts, Pericarpium Citri Reticulatae Viride, 105 parts of Radix Kansuis, 105 parts of Radix Scutellariaes, 105 parts of Pericarpium Citri tangerinaes, 150 parts, Fructus Hordei Germinatus.
Method for making: get 250 parts of the red Radix Paeoniae Albas, 105 parts of Rhizoma Cyperis, 105 parts, Pericarpium Citri Reticulatae Viride, 105 parts of Radix Kansuis, 105 parts of Radix Scutellariaes, 105 parts of Pericarpium Citri tangerinaes, 150 parts, Fructus Hordei Germinatus, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed at 60-65 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, obtain.
Embodiment 3:
Raw material of Chinese medicine: 200 parts of the red Radix Paeoniae Albas, 60 parts of Rhizoma Cyperis, 60 parts, Pericarpium Citri Reticulatae Viride, 60 parts of Radix Kansuis, 60 parts of Radix Scutellariaes, 60 parts of Pericarpium Citri tangerinaes, 100 parts, Fructus Hordei Germinatus.
Method for making: get 200 parts of the red Radix Paeoniae Albas, 60 parts of Rhizoma Cyperis, 60 parts, Pericarpium Citri Reticulatae Viride, 60 parts of Radix Kansuis, 60 parts of Radix Scutellariaes, 60 parts of Pericarpium Citri tangerinaes, 100 parts, Fructus Hordei Germinatus, water decocts secondary, the 8-10 that each water consumption is medical material weight doubly measures, decoct secondary, each 1-2 hour, filter, filtrate is condensed at 60-65 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, obtain.
Embodiment 4:
1) clinical data: chronic hepatitis 40 examples, male 22 examples, female's 18 examples, 20～54 years old age.
The present invention be take traditional Chinese medical science chronic hepatitis as example, through 40 routine clinical observations.Selecting the tcm diagnosis chronic hepatitis is standard: limb is soft weak, weak from head to foot; Poor appetite, abdominal distention, dyspepsia; Face is pitch-dark, hepatic face is arranged; Dull pain in liver; Hepatic fibrosis is serious; It is undesired that liver function transaminase continues, and other index is as defective as plasma albumin, blood total bilirubin etc.As above symptom, can make a definite diagnosis.
In making a definite diagnosis the object of observation, male 22 examples, female's 18 examples, without other serious disease, 20～54 years old age.
2) efficacy determination:
Produce effects: weak alleviation, with it energetically, hepatic region is comfortable, and hepatic face is taken on a new look to some extent, and it is pale that face becomes;
Effectively: weak solution, with it energetically, abdominal distention, poor appetite, hepatic face are alleviated to some extent;
Invalid: disease is unchanged.
3) Therapeutic Method: oral, each 20 milliliters of the embodiment of the present invention 1, every day 3 times, half an hour, 3 months be a course for the treatment of after meal.
4) therapeutic outcome: the patient takes the embodiment of the present invention 1 Chinese medicine oral liquid, and after 1 month, symptom has alleviation, and after taking 3 months, symptom is obviously improved.40 people of clinical experiment, produce effects 20 people wherein, effective 15 people, invalid 5 people, total effective rate 87.5%.
Embodiment 5:
Model case: leaf, 25 years old, the female, the chronic hepatitis patient main cause is weak, poor appetite, right rib dull pain companion dry mouth with bitter taste 1 year, and in locality, the chemical examination liver function is undesired, take this invention after 1 month symptom alleviation is arranged, after taking 3 months, symptom is obviously improved, and checks after three courses for the treatment of that liver function is normal, and subjective symptoms disappears.
Embodiment 6:
Model case: Lee, 40 years old, the man, suffered from chronic hepatitis 2 years, side of body pain, abdominal distention, decreased food intake, weak, take this invention after 1 month symptom alleviation is arranged, after taking 3 months, symptom is obviously improved, and checks after three courses for the treatment of that liver function is normal, the subjective symptoms disappearance.
Claims (1)
1. treat the preparation method of the red Radix Paeoniae Alba Chinese medicine oral liquid of chronic hepatitis, it is characterized in that: concrete steps are as follows
Get 200 parts of the red Radix Paeoniae Albas, 60 parts of Rhizoma Cyperis, 60 parts, Pericarpium Citri Reticulatae Viride, 60 parts of Radix Kansuis, 60 parts of Radix Scutellariaes, 60 parts of Pericarpium Citri tangerinaes, 100 parts, Fructus Hordei Germinatus, water decocts secondary, 10 times of amounts that each water consumption is medical material weight, decoct secondary, each 2 hours, filter, filtrate is condensed at 65 ℃ and surveys the clear paste that relative density is 1.25, adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing 24 hours, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 67%, add sucrose 20%, refined honey 12%, antiseptic 3%, the stock solution embedding, irradiation sterilization, packed products, make oral liquid, obtain.
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| CN1104903C (en) * | 2000-05-24 | 2003-04-09 | 漳州片仔癀药业股份有限公司 | Medicine for treating hepatitis and productive process thereof |
| CN100425275C (en) * | 2004-12-18 | 2008-10-15 | 赵莉萍 | Medicine for treating hepatitis and its preparing process |
| CN100534517C (en) * | 2006-07-10 | 2009-09-02 | 王培才 | Medicine for treating hepatic disease and nephrosis |
| CN101357184A (en) * | 2008-08-22 | 2009-02-04 | 朱秀进 | Chinese traditional medicine for treating hepatosis and preparation method thereof |
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Owner name: HAIMEN FENGCHENG TOURIST ATTRACTIONS DEVELOPMENT C Free format text: FORMER OWNER: HUANG YUN Effective date: 20140416 |
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| C41 | Transfer of patent application or patent right or utility model | ||
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Free format text: CORRECT: ADDRESS; FROM: 523120 DONGGUAN, GUANGDONG PROVINCE TO: 226152 NANTONG, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20140416 Address after: Yu Dong Wenfeng road 226152 Jiangsu Haimen city of Nantong Province Patentee after: Haimen Fengcheng tourist attractions development Co., Ltd. Address before: 523120 A elegant department store, Dongcheng style walking street, Dongguan, Dongcheng District, Guangdong Patentee before: Huang Yun |