Semen Platycladi Chinese medicine preparation and the preparation method of alleviate depression disease
Technical field
The invention belongs to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation of Semen Platycladi for alleviate depression disease and preparation method.
Background technology
Depression is a kind of disease take affective disorder as main manifestations.Along with social competition's aggravation, depression has become the high incidence disease of society.According to World Health Organization's prediction, to the year two thousand twenty, depression will become the second largest disease of prestige victimization class health, be only second to ischemic heart desease.Depression belongs to " melancholia " category in motherland's medical science, and the traditional Chinese medical science thinks that melancholia is because feelings will is not relaxed, the caused class disease of depression and stagnation of QI.Main manifestations for feeling depressed, distending pain over the hypochondrium or irritability is kind cries and the various complicated symptoms such as insomnia.Depressed main pathogenesis is because feelings will is hindered, due to depression of liver-QI causes that gradually the five internal organs mechanism of qi gets along well.But be mainly liver, spleen, the heart is got involved and disorder of QI and blood forms.The traditional Chinese medical science is thought the generation of melancholia because of the institute of disgruntled, grieved, worried seven emotions wound in a word, causes that the liver failing to maintain the normal flow of QI, spleen lose transporting, the internal organs yin and yang qi and blood disorder forms.The just cause of disease stagnation of QI and hold damp-phlegm, food stagnation, heat stagnation person under the arm, how true card; Prolonged illness is by gas and blood, and Sthenia is transforming into asthenia, as for a long time strongly fragrant, overtaxes one's nerves, and hyperactivity of fire caused by deficiency of YIN etc. all belong to deficiency syndrome.The depressive patients Clinical symptoms is depressed, and part patient is with obvious anxiety, go down as feature take depressed, interest blank and bulesis, and often with insomnia, loss of appetite, the somatization such as lose weight.Over nearly 20 years, along with the progress to depression etiology and pathological research, the leading position of Drug therapy is progressively established.In general the process of western medical treatment depression is exactly for its symptom treatment, adopts antidepressants or calm class Western medicine to carry out mitigate the disease.On the whole, western medical treatment depression advantage is that therapeutic effect is obvious, instant effect, but also exist huge shortcoming simultaneously, because the western medical treatment depression has been ignored the treatment of depression cause of disease old complaint just for disease, make treatment only rest on surface, can not tackle the problem at its root.Simultaneously, the life-time service of Western medicine makes toxic and side effects large, and easily recurrence, produce drug resistance, and these are all that Western medicine is unavoidable.Adopt the means of Chinese medicine to carry out Cure of depression, giving consideration to both the incidental and fundamental, be a channel extremely leaved for development, and applied widely, there is its original effect the treatment aspect.
Summary of the invention
Purpose of the present invention is exactly in order to overcome the above-mentioned defect of prior art, and a kind of advantages of perfect compatibility that has is provided, have no side effect, and Semen Platycladi Chinese medicine preparation and the preparation method of the reliable alleviate depression disease of curative effect.
For achieving the above object, the present invention is achieved by the following technical solutions:
The Semen Platycladi Chinese medicine preparation of alleviate depression disease, made by the raw material of Chinese medicine of following weight portion:
Semen Platycladi 100-300 part, Radix Astragali 100-300 part, Radix Codonopsis 80-280 part, Rhizoma Atractylodis Macrocephalae 50-150 part, Cortex Cinnamomi 50-150 part, Fructus Citri Sarcodactylis 50-150 part, Rhizoma Curcumae 50-150 part, Caulis Bambusae In Taenia 60-180 part.
The Semen Platycladi Chinese medicine preparation of described alleviate depression disease, made by the raw material of Chinese medicine of following weight portion:
200 parts of Semen Platycladi, 200 parts of the Radixs Astragali, 180 parts of Radix Codonopsis, 100 parts of the Rhizoma Atractylodis Macrocephalaes, 100 parts of Cortex Cinnamomis, 100 parts of Fructus Citri Sarcodactylis, 100 parts of Rhizoma Curcumae, 120 parts of Caulis Bambusae In Taenia.
The preparation method of the Semen Platycladi Chinese medicine preparation of described alleviate depression disease, its preparation method is:
Take in proportion 200 parts of above-mentioned raw material of Chinese medicine Semen Platycladi, 200 parts of the Radixs Astragali, 180 parts of Radix Codonopsis, 100 parts of the Rhizoma Atractylodis Macrocephalaes, 100 parts of Cortex Cinnamomis, 100 parts of Fructus Citri Sarcodactylis, 100 parts of Rhizoma Curcumae, 120 parts of Caulis Bambusae In Taenia, cleaning is dried, be ground into granule, soaked 1.5 hours, then decoct with water twice, add for the first time the water of 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add for the second time the water of 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Usage and consumption: oral Chinese medicine preparation of the present invention, each 180ml, every day 2 times, after meal half an hour, 4 weeks were 1 course for the treatment of.
The pharmacological action of crude drug of the present invention is as follows, Semen Platycladi: sweet, flat, and GUIXIN, kidney, large intestine channel, tranquilizing by nourishing the heart, loosening bowel to relieve constipation; The Radix Astragali: sweet, tepor, return spleen, lung meridian, tonifying Qi and lifting yang, benefit are defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, water detumescence; Radix Codonopsis: sweet, flat, return spleen, lung meridian, invigorating the spleen and replenishing QI, promote the production of body fluid and nourish blood; The Rhizoma Atractylodis Macrocephalae: temperature, bitter, sweet enters spleen channel, stomach warp, air making-up and spleen enlivening, dampness diuretic, hidroschesis; Cortex Cinnamomi: hot, sweet, hot, return kidney, spleen, the heart, Liver Channel, mend that fire is supporing yang, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian; Fructus Citri Sarcodactylis: acrid, bitter, warm, return liver, spleen, stomach, lung meridian, depressed liver-energy dispersing and QI regulating and stomach and alleviating pain, drying dampness to eliminate phlegm; Rhizoma Curcumae: acrid, bitter, warm, return liver, spleen channel, removing blood stasis, promoting the circulation of QI to relieve pain; Caulis Bambusae In Taenia: sweet, be slightly cold, return lung, stomach, gallbladder meridian, removing heat-phlegm, relieve restlessness and prevent vomiting; All medicines are played the merit of invigorating spleen and nourishing heart, benefiting QI and nourishing blood altogether, and Chinese medicine preparation of the present invention has remarkable therapeutic effect to the insufficiency of both heart and spleen depressive disorders patient, and can alleviate rapidly worries too much is difficult to resolve, forgetful insomnia, chest distress and palpitation symptoms; Accompanied symptoms has shallow complexion, fatigue and weakness, the indigestion and loss of appetite symptom of hyperhidrosis, and this preparation has no side effect, and therapeutic effect is remarkable, has fundamentally removed patient's misery.
The specific embodiment
EXAMPLE l:
Raw material of Chinese medicine: 200 parts of Semen Platycladi, 200 parts of the Radixs Astragali, 180 parts of Radix Codonopsis, 100 parts of the Rhizoma Atractylodis Macrocephalaes, 100 parts of Cortex Cinnamomis, 100 parts of Fructus Citri Sarcodactylis, 100 parts of Rhizoma Curcumae, 120 parts of Caulis Bambusae In Taenia.
preparation method: take in proportion 200 parts of above-mentioned raw material of Chinese medicine Semen Platycladi, 200 parts of the Radixs Astragali, 180 parts of Radix Codonopsis, 100 parts of the Rhizoma Atractylodis Macrocephalaes, 100 parts of Cortex Cinnamomis, 100 parts of Fructus Citri Sarcodactylis, 100 parts of Rhizoma Curcumae, 120 parts of Caulis Bambusae In Taenia, cleaning is dried, be ground into granule, soaked 1.5 hours, then decoct with water twice, the water that adds for the first time 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filter, the water that adds for the second time 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Embodiment 2
Raw material of Chinese medicine: 300 parts of Semen Platycladi, 300 parts of the Radixs Astragali, 280 parts of Radix Codonopsis, 150 parts of the Rhizoma Atractylodis Macrocephalaes, 150 parts of Cortex Cinnamomis, 150 parts of Fructus Citri Sarcodactylis, 150 parts of Rhizoma Curcumae, 180 parts of Caulis Bambusae In Taenia.
preparation method: take in proportion 300 parts of above-mentioned raw material of Chinese medicine Semen Platycladi, 300 parts of the Radixs Astragali, 280 parts of Radix Codonopsis, 150 parts of the Rhizoma Atractylodis Macrocephalaes, 150 parts of Cortex Cinnamomis, 150 parts of Fructus Citri Sarcodactylis, 150 parts of Rhizoma Curcumae, 180 parts of Caulis Bambusae In Taenia, cleaning is dried, be ground into granule, soaked 1.5 hours, then decoct with water twice, the water that adds for the first time 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filter, the water that adds for the second time 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Embodiment 3:
Raw material of Chinese medicine: 100 parts of Semen Platycladi, 100 parts of the Radixs Astragali, 80 parts of Radix Codonopsis, 50 parts of the Rhizoma Atractylodis Macrocephalaes, 50 parts of Cortex Cinnamomis, 50 parts of Fructus Citri Sarcodactylis, 50 parts of Rhizoma Curcumae, 60 parts of Caulis Bambusae In Taenia.
Preparation method: take in proportion 100 parts of above-mentioned raw material of Chinese medicine Semen Platycladi, 100 parts of the Radixs Astragali, 80 parts of Radix Codonopsis, 50 parts of the Rhizoma Atractylodis Macrocephalaes, 50 parts of Cortex Cinnamomis, 50 parts of Fructus Citri Sarcodactylis, 50 parts of Rhizoma Curcumae, 60 parts of Caulis Bambusae In Taenia, cleaning is dried, be ground into granule, soaked 1.5 hours, then decoct with water twice, add for the first time the water of 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add for the second time the water of 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Embodiment 4:
Clinical trial
1) physical data:
Adopt Chinese medicine preparation of the present invention to treat altogether 50 routine patients, male 20 examples wherein, female's 30 examples; Age is 30-75 years old, average 52.5 years old, and medical history 1-10.
2) diagnostic criteria: primary symptom: worry too much be difficult to resolve, forgetful insomnia, chest distress and palpitation symptoms; Accompanied symptoms has shallow complexion, fatigue and weakness, hyperhidrosis indigestion and loss of appetite; The tongue arteries and veins is light red tongue, white and thin fur, stringy and thready pulse or counts accurately.
3) Therapeutic Method: the oral embodiment of the present invention 1 Chinese medicine decoction, each 180ml, every day 2 times, after meal half an hour, 4 weeks were 1 course for the treatment of, evaluated therapeutic outcome 3 courses for the treatment of.
4) the standard of curative effect evaluation:
Recovery from illness: above-mentioned primary symptom disappears;
Produce effects: above-mentioned primary symptom disappears substantially;
Effectively: above-mentioned primary symptom is improved;
Invalid: above-mentioned primary symptom is without obvious improvement.
5) therapeutic outcome: 50 3 of routine patients result course for the treatment of recovery from illness, 27 examples, produce effects 10 examples, effective 10 examples, invalid 3 examples, total effective rate 94%.
Embodiment 5:
Model case: clock, 35 years old, the female, worry too much be difficult to resolve, forgetful insomnia, chest distress and palpitation symptoms; Shallow complexion, fatigue and weakness, hyperhidrosis are indigestion and loss of appetite; The tongue arteries and veins is light red tongue, white and thin fur, thready and rapid pulse, and the Chinese medicine preparation of taking embodiment 1 takes effect 1 course for the treatment of, 3 recoveries from illness courses for the treatment of.
Embodiment 6:
Model case: Zhu, 70 years old, the man, worry too much be difficult to resolve, forgetful insomnia, chest distress and palpitation symptoms; Accompanied symptoms has shallow complexion, fatigue and weakness, hyperhidrosis indigestion and loss of appetite; The tongue arteries and veins is light red tongue, white and thin fur, stringy and thready pulse, and the Chinese medicine preparation of taking embodiment 1 takes effect 1 course for the treatment of, 3 recoveries from illness courses for the treatment of.