CN102688429A

CN102688429A - Medicinal tincture for treating fungal diseases

Info

Publication number: CN102688429A
Application number: CN2012101879271A
Authority: CN
Inventors: 王建国; 梁亮
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-06-08
Filing date: 2012-06-08
Publication date: 2012-09-26
Anticipated expiration: 2032-06-08
Also published as: CN102688429B

Abstract

The invention discloses a medicinal tincture for treating fungal diseases. The medicinal tincture consists of the following components in part by weight: 4 to 6 parts of pseudolarix, 4 to 6 parts of belvedere fruit, 4 to 6 parts of selinum japenious seed, 2 to 4 parts of coptis root, 2 to 4 parts of phellodendron, 3 to 4 parts of baikal skullcap root, 2 to 3 parts of rhubarb, 2 to 4 parts of lightyellow sophora root, 2 to 3 parts of sessile stemona root, 2 to 3 parts of honeysuckle, 3 to 4 parts of dandelion and 3 to 4 parts of weeping forsythia. The medicinal tincture is prepared by the following steps of: mixing the components to prepare Chinese medicinal powder, and putting the Chinese medicinal powder into a closed container; adding 1,000 to 1,500 parts of 50 to 70 percent ethanol, covering the medicinal powder, impregnating and stirring, pouring supernatant in the container out for later use after 5 to 6 days; and mixing 40 to 60g of salicylic acid, 90 to 110g of benzoic acid and 830 to 870ml of supernatant to prepare 1,000ml of the medicinal tincture. Compared with the prior art, the medicinal tincture is an externally applied medicine integrating traditional and western medicines, small in side effect, simple in preparation method, prepared from readily available raw materials and obvious in curative effect.

Description

The medicinal tincture of treatment dermatomycosis

Technical field

The present invention relates to a kind of medicinal tincture of treating dermatomycosis, is a kind of external used medicine of treating dermatomycosiss such as the tinea manuum, tinea pedis, tinea cruris, tinea corporis.

Background technology

Dermatomycosis is also claimed dermatomycosis, is meant one big type of infectious disease by the caused human skin of pathogenic fungi and mucosa, hair and first-class skin appendages.Dermatophytosis is the main pathogenic bacterium of dermatomycosis; Trichophyton, trichophyton gypseum, acrothesium floccosum, Trichophyton verrucosum, Microsporum canis etc. are arranged, and the common feature of this type of disease is: sickness rate is high, have infectiousness, be prone to recurrence or infect.Unreasonable especially, nonstandard treatment can cause outbreak repeatedly, treatment repeatedly, influences patient's quality of life greatly.The tinea manuum, tinea pedis, tinea cruris, tinea corporis are the performance of vesicle squama type clinically, and phlysis just takes place, and how many numbers differs; The dry back of bleb liquid desquamation, scope day by day enlarges, and desquamation place pachylosis of a specified duration thickens; Dermatoglyph is wide dark, loses normal gloss, pliability; That touches has a rough sand sense, and this type dermatomycosis can betide any age.At present this type of treatment disease in, western drug is a lot, mostly Western medicine is the oral medicine of chemosynthesis, Time of Administration is long can to produce great side effect to human body, other that perhaps cause sufferer infect type diseases, unsatisfactory curative effect.

Summary of the invention

The present invention be directed to the defective of present this type of dermatomycosis of treatment, a kind of medicinal tincture of treating dermatomycosis is provided, this medicinal tincture is the bonded external used medicine of Chinese medicine and western medicine, and side effect is little, manufacture method is simple, the convenience, evident in efficacy of drawing materials.

Realize that the technical scheme that the foregoing invention purpose adopts is: a kind of medicinal tincture of treating dermatomycosis; It is become to be grouped into by each of following weight portion: Cortex Pseudolaricis 4-6 part, Fructus Kochiae 4-6 part, Fructus Cnidii 4-6 part, Rhizoma Coptidis 2-4 part, Cortex Phellodendri 2-4 part, Radix Scutellariae 3-4 part, Radix Et Rhizoma Rhei 2-3 part, Radix Sophorae Flavescentis 2-4 part, Radix Stemonae 2-3 part, Flos Lonicerae 2-3 part, Herba Taraxaci 3-4 part, Fructus Forsythiae 3-4 part;

Prepare the method for tincture with above-mentioned parts by weight of Chinese traditional medicine, carry out according to following steps:

A, with Cortex Pseudolaricis 4-6 part, be prepared into Chinese medicine medicated powder after Fructus Kochiae 4-6 part, Fructus Cnidii 4-6 part, Rhizoma Coptidis 2-4 part, Cortex Phellodendri 2-4 part, Radix Scutellariae 3-4 part, Radix Et Rhizoma Rhei 2-3 part, Radix Sophorae Flavescentis 2-4 part, Radix Stemonae 2-3 part, Flos Lonicerae 2-3 part, Herba Taraxaci 3-4 part, Fructus Forsythiae 3-4 part are mixed and place hermetic container;

B, in container, add ethanol 1000-1500 part of 50%-75%, medicated powder is covered dipping and stirs, place hypsokinesis in 5-6 days and go out the supernatant in the container, subsequent use;

C, get the medicinal tincture of processing 1000ml after salicylic acid 40-60g, benzoic acid 90-110g, supernatant 830-870ml mix.

The best group of each Chinese medicine ingredients becomes umber to be: 5 parts of Cortex Pseudolaricis, 5 parts of the Fructus Kochiae, 5 parts of Fructus Cnidiis, 3 parts of Rhizoma Coptidis, 3 parts of Cortex Phellodendris, 3 parts of Radix Scutellariaes, 3 parts of Radix Et Rhizoma Rhei, 3 parts of Radix Sophorae Flavescentiss, 3 parts of the Radixs Stemonae, 3 parts of Flos Loniceraes, 3 parts of Herba Taraxacis, 3 parts of Fructus Forsythiaes.

Compare with existing medicine, this medicinal tincture is the bonded external used medicine of Chinese medicine and western medicine, and side effect is little, manufacture method is simple, the convenience, evident in efficacy of drawing materials.

The pharmacological action of each composition of the present invention is following:

Cortex Pseudolaricis:, have that system is itched, the merit of antibiotic parasite killing for controlling the key medicine of tinea skin ulcer;

The Fructus Kochiae, Fructus Cnidii: clearing away heat-damp and promoting diuresis, the kind skin pruritus of treating it is reported that its infusion has inhibitory action to multiple tinea bacterium;

Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication;

Radix Et Rhizoma Rhei: eliminating fire and detoxication, removing heat from blood detumescence;

Radix Sophorae Flavescentis, the Radix Stemonae: diarrhea of heat type is wet, wind dispelling insecticide, and the experiment proof has antifungic action;

Flos Lonicerae, Herba Taraxaci, Fructus Forsythiae: heat-clearing and toxic substances removing;

Salicylic acid, benzoic acid are antifungal drug.

The specific embodiment

Below in conjunction with embodiment the present invention is further specified.

The medicinal tincture of this treatment dermatomycosis; Each one-tenth by following weight portion is grouped into: Cortex Pseudolaricis 4-6 part, Fructus Kochiae 4-6 part, Fructus Cnidii 4-6 part, Rhizoma Coptidis 2-4 part, Cortex Phellodendri 2-4 part, Radix Scutellariae 3-4 part, Radix Et Rhizoma Rhei 2-3 part, Radix Sophorae Flavescentis 2-4 part, Radix Stemonae 2-3 part, Flos Lonicerae 2-3 part, Herba Taraxaci 3-4 part, Fructus Forsythiae 3-4 part.

The method for preparing tincture with above-mentioned parts by weight of Chinese traditional medicine is carried out according to following steps:

B, in container, add ethanol 1000-1500 part of 50%-75%, the alcoholic acid amount of getting be as the criterion can medicated powder being covered dipping, and ethanol covers dipping with medicated powder and fully stirs, and places hypsokinesis in 5-6 days and goes out the supernatant in the container, and is subsequent use;

Wherein, when medicated powder was the unit amount of getting with the gram, the alcoholic acid amount of getting unit was ml, and by that analogy, when medicated powder was the unit amount of getting with the kilogram, the ethanol amount of getting unit was L.

With Cortex Pseudolaricis 40 grams; The Fructus Kochiae 60 grams, Fructus Cnidii 40 grams, Rhizoma Coptidis 30 grams, Cortex Phellodendri 20 grams, Radix Scutellariae 30 grams, Radix Et Rhizoma Rhei 30 grams, Radix Sophorae Flavescentis 40 grams, the Radix Stemonae 20 grams, Flos Lonicerae 20 grams, Herba Taraxaci 30 grams, Fructus Forsythiae 30 grams are pulverized and are put in the hermetic container; Add 50%～75% ethanol 1000ml, cover dipping, stir; Place after 6 days, inclining supernatant.Get salicylic acid 50g, benzoic acid 100g again, add gained Chinese medicine clear liquid 850ml and process the 1000ml medicinal tincture.

External method: smear every day 2 times in the affected part.1 week of external can make the state of an illness take a turn for the better to some extent, and part patient can fully recover in 3 days.

The present invention does clinical observation with 162 routine cases, consequently:

96 examples-male's 56 examples, women's 40 examples are organized in treatment, age 5-64 year, disease time 1 week-2 year, 2.8 weeks of average course of treatment;

Matched group 66 examples-male's 36 examples, women's 30 examples, age 6-55 year, disease time 1 week-2 year, 3.4 weeks of average course of treatment.

The result who with form this Linchuan is observed below does detailed comparison, sees the following form:

Group	The treatment group	Matched group
			The example number	96 examples	66 examples
The routine number of fully recovering	80 examples	33 examples
			Produce effects example number	14 examples	12 examples
Effective routine number	2 examples	10 examples
			Invalid routine number	0 example	11 examples
Total effective routine number	96 examples	46 examples
			Total effective rate	100%	83.2%

Example 1: the Wang, the man, 21 years old, the student of Yutian County suffered from tinea pedis 1 year, very itch unbearably, repeated multiple times use miconazole, Compound Flavescent Sophora and Salicylic Acid Powder, etc. treatment, all do not cure.With the present invention's treatment, recovery from illness in 8 days.

Example 2: Lee, 39 years old, the man, people from Ninghe County, Tianjin suffered from tinea versicolor 1 year, external the present invention, day 3 times, the recovery from illness of 3 weeks.

Example 3: Liu, the man, 52 years old, people from Yutian County suffered from tinea cruris 2 months, failed to cure through multi-treatment, took the present invention outward, day 3 times, the recovery from illness of 3 weeks.

More than disclosedly be merely specific embodiment of the present invention, but the present invention is not limited thereto, any those skilled in the art can think variation, all should drop within protection scope of the present invention.

Claims

1. medicinal tincture of treating dermatomycosis; It is characterized in that; It is become to be grouped into by each of following weight portion: Cortex Pseudolaricis 4-6 part, Fructus Kochiae 4-6 part, Fructus Cnidii 4-6 part, Rhizoma Coptidis 2-4 part, Cortex Phellodendri 2-4 part, Radix Scutellariae 3-4 part, Radix Et Rhizoma Rhei 2-3 part, Radix Sophorae Flavescentis 2-4 part, Radix Stemonae 2-3 part, Flos Lonicerae 2-3 part, Herba Taraxaci 3-4 part, Fructus Forsythiae 3-4 part;

2. the medicinal tincture of treatment dermatomycosis according to claim 1; It is characterized in that; The best group of described each Chinese medicine ingredients becomes umber to be: 5 parts of Cortex Pseudolaricis, 5 parts of the Fructus Kochiae, 5 parts of Fructus Cnidiis, 3 parts of Rhizoma Coptidis, 3 parts of Cortex Phellodendris, 3 parts of Radix Scutellariaes, 3 parts of Radix Et Rhizoma Rhei, 3 parts of Radix Sophorae Flavescentiss, 3 parts of the Radixs Stemonae, 3 parts of Flos Loniceraes, 3 parts of Herba Taraxacis, 3 parts of Fructus Forsythiaes.