CN103599443A - Medicine tincture for treating fungal dermatopathy and preparation method thereof - Google Patents

Abstract

The invention discloses medicine tincture for treating fungal dermatopathy and a preparation method thereof. The medicine tincture is characterized by comprising the following components: 5-15g of hedyotis diffusa, 5-15g of cortex dictamni, 5-15g of pseudo-ginseng, 5-15g of fructus kochiae, 5-15g of fructus cnidii, 10-20g of coptidis rhizoma, 5-15g of prepared rhizome of rehmannia and 14-16g of radix scutellariae. The preparation method comprises the following steps: mixing the medicinal materials, adding 60% alcohol and the like. Compared with a conventional medicine, the medicine tincture is an external Chinese and western medicine combined medicine and has small side effects and an obvious curative effect; the preparation method is simple; the materials are available.

Description

Medicinal tincture for the treatment of dermatomycosis and preparation method thereof

Technical field

The present invention relates to a kind of medicinal tincture for the treatment of dermatomycosis, is a kind of external used medicine for the treatment of the dermatomycosiss such as the tinea manuum, tinea pedis, tinea cruris, tinea corporis, the invention still further relates to the manufacture method of this medicine.

Background technology

Dermatomycosis, also claims dermatomycosis, refers to the large class infectious disease by the caused human skin of pathogenic fungi and mucosa, hair and first-class skin appendages.Dermatophytosis is the Main Pathogenic Bacteria of dermatomycosis, have trichophyton, trichophyton gypseum, acrothesium floccosum, Trichophyton verrucosum, Microsporum canis etc., the common feature of this type of disease is: sickness rate is high, have infectiousness, easily recurrence or infect again.Unreasonable especially, nonstandard treatment can cause outbreak repeatedly, treatment repeatedly, affects greatly patient's quality of life.The tinea manuum, tinea pedis, tinea cruris, tinea corporis clinically the vesicle squama types that are show more, just there is phlysis, how many numbers differs, desquamation after bleb liquid is dry, and scope day by day expands, desquamation place pachylosis of a specified duration thickens, dermatoglyph is wide dark, loses normal gloss, pliability, that touches has a rough sand sense, and this class dermatomycosis can betide any age.At present this class disease for the treatment of in, western drug is a lot, Western medicine mostly is the oral medicine of chemosynthesis, Time of Administration is long can produce great side effect to human body, or cause sufferer other infect class diseases, unsatisfactory curative effect.

Summary of the invention

The present invention be directed to the defect of current this type of dermatomycosis for the treatment of, a kind of medicinal tincture for the treatment of dermatomycosis is provided, this medicinal tincture is the external used medicine of Chinese medicine and western medicine combination, and side effect is little, manufacture method is simple, the convenience, evident in efficacy of drawing materials.

The technical scheme that realizes the employing of foregoing invention object is:

A medicinal tincture for the treatment of dermatomycosis, is characterized in that, described medicinal tincture comprises following component:

Herba Hedyotidis Diffusae 5-15g, Cortex Dictamni 5-15g, Radix Notoginseng 5-15g, Fructus Kochiae 5-15g, Fructus Cnidii 5-15g, Rhizoma Coptidis 10-20g, Radix Rehmanniae Preparata 5-15g, Radix Scutellariae 4-16g, Radix Et Rhizoma Rhei 6-12g, Radix Sophorae Flavescentis 10-20g, Radix Stemonae 6-12g, Flos Lonicerae 6-12g, Herba Taraxaci 4-16g, Fructus Forsythiae 4-16g, Radix Saposhnikoviae 5-15g, Pheretima 5-15g, Periostracum Cicadae 6-12g.

By the method for the Chinese drug preparation tincture of above-mentioned weight portion, carry out in accordance with the following steps:

A, by Herba Hedyotidis Diffusae 5-15g, Cortex Dictamni 5-15g, Radix Notoginseng 5-15g, Fructus Kochiae 5-15g, Fructus Cnidii 5-15g, Rhizoma Coptidis 10-20g, Radix Rehmanniae Preparata 5-15g, Radix Scutellariae 4-16g, Radix Et Rhizoma Rhei 6-12g, Radix Sophorae Flavescentis 10-20g, the Radix Stemonae 6-12g, Flos Lonicerae 6-12g, Herba Taraxaci 4-16g, Fructus Forsythiae 4-16g, Radix Saposhnikoviae 5-15g, Pheretima 5-15g, Periostracum Cicadae 6-12g are prepared into Chinese medicinal powder after mixing and are placed in hermetic container;

B, to the ethanol 300-400ml that adds 60% in container, medicated powder is covered and floods and stir, place hypsokinesis in 7 days and go out the supernatant in container, standby;

C, get after salicylic acid 4-6g, benzoic acid 9-11g, supernatant 80-90ml mix and make medicinal tincture.

The best group of each Chinese medicine ingredients becomes umber to be: Herba Hedyotidis Diffusae 10g, Cortex Dictamni 10g, Radix Notoginseng 10g, Fructus Kochiae 10g, Fructus Cnidii 10g, Rhizoma Coptidis 15g, Radix Rehmanniae Preparata 10g, Radix Scutellariae 10g, Radix Et Rhizoma Rhei 9g, Radix Sophorae Flavescentis 15g, Radix Stemonae 9g, Flos Lonicerae 9g, Herba Taraxaci 10g, Fructus Forsythiae 10g, Radix Saposhnikoviae 10g, Pheretima 10g, Periostracum Cicadae 9g.

Compare with existing medicine, this medicinal tincture is the external used medicine of Chinese medicine and western medicine combination, and side effect is little, manufacture method is simple, the convenience, evident in efficacy of drawing materials.

The specific embodiment

Below in conjunction with embodiment, the present invention will be further described.

Embodiment 1: a kind of medicinal tincture for the treatment of dermatomycosis, and described medicinal tincture comprises following component:

Herba Hedyotidis Diffusae 10g, Cortex Dictamni 10g, Radix Notoginseng 10g, Fructus Kochiae 10g, Fructus Cnidii 10g, Rhizoma Coptidis 15g, Radix Rehmanniae Preparata 10g, Radix Scutellariae 10g, Radix Et Rhizoma Rhei 9g, Radix Sophorae Flavescentis 15g, Radix Stemonae 9g, Flos Lonicerae 9g, Herba Taraxaci 10g, Fructus Forsythiae 10g, Radix Saposhnikoviae 10g, Pheretima 10g, Periostracum Cicadae 9g.

By the method for the Chinese drug preparation tincture of above-mentioned weight portion, carry out in accordance with the following steps:

A, by Herba Hedyotidis Diffusae 10g, Cortex Dictamni 10g, Radix Notoginseng 10g, Fructus Kochiae 10g, Fructus Cnidii 10g, Rhizoma Coptidis 15g, Radix Rehmanniae Preparata 10g, Radix Scutellariae 10g, Radix Et Rhizoma Rhei 9g, Radix Sophorae Flavescentis 15g, Radix Stemonae 9g, Flos Lonicerae 9g, Herba Taraxaci 10g, Fructus Forsythiae 10g, Radix Saposhnikoviae 10g, Pheretima 10g, Periostracum Cicadae 9g are prepared into Chinese medicinal powder after mixing and are placed in hermetic container;

B, to the ethanol 350ml that adds 60% in container, the taken amount of ethanol be as the criterion medicated powder can be covered to dipping, ethanol covers medicated powder dipping and fully stirs, and places hypsokinesis in 7 days and goes out the supernatant in container, standby;

C, get after salicylic acid 5g, benzoic acid 10g, supernatant 85ml mix and make medicinal tincture.

Embodiment 2: a kind of medicinal tincture for the treatment of dermatomycosis, and described medicinal tincture comprises following component:

Herba Hedyotidis Diffusae 5g, Cortex Dictamni 5g, Radix Notoginseng 5g, Fructus Kochiae 5g, Fructus Cnidii 5g, Rhizoma Coptidis 10-20g, Radix Rehmanniae Preparata 5g, Radix Scutellariae 4g, Radix Et Rhizoma Rhei 6g, Radix Sophorae Flavescentis 10-20g, Radix Stemonae 6g, Flos Lonicerae 6g, Herba Taraxaci 4g, Fructus Forsythiae 4g, Radix Saposhnikoviae 5g, Pheretima 5g, Periostracum Cicadae 6g.

By the method for the Chinese drug preparation tincture of above-mentioned weight portion, carry out in accordance with the following steps:

A, by Herba Hedyotidis Diffusae 5g, Cortex Dictamni 5g, Radix Notoginseng 5g, Fructus Kochiae 5g, Fructus Cnidii 5g, Rhizoma Coptidis 10-20g, Radix Rehmanniae Preparata 5g, Radix Scutellariae 4g, Radix Et Rhizoma Rhei 6g, Radix Sophorae Flavescentis 10-20g, Radix Stemonae 6g, Flos Lonicerae 6g, Herba Taraxaci 4g, Fructus Forsythiae 4g, Radix Saposhnikoviae 5g, Pheretima 5g, Periostracum Cicadae 6g are prepared into Chinese medicinal powder after mixing and are placed in hermetic container;

B, to the ethanol 300ml that adds 60% in container, the taken amount of ethanol be as the criterion medicated powder can be covered to dipping, ethanol covers medicated powder dipping and fully stirs, and places hypsokinesis in 7 days and goes out the supernatant in container, standby;

C, get after salicylic acid 4g, benzoic acid 9g, supernatant 80ml mix and make medicinal tincture.

Embodiment 3: a kind of medicinal tincture for the treatment of dermatomycosis, and described medicinal tincture comprises following component:

Herba Hedyotidis Diffusae 15g, Cortex Dictamni 15g, Radix Notoginseng 15g, Fructus Kochiae 15g, Fructus Cnidii 15g, Rhizoma Coptidis 10-20g, Radix Rehmanniae Preparata 15g, Radix Scutellariae 16g, Radix Et Rhizoma Rhei 12g, Radix Sophorae Flavescentis 10-20g, Radix Stemonae 12g, Flos Lonicerae 12g, Herba Taraxaci 16g, Fructus Forsythiae 16g, Radix Saposhnikoviae 15g, Pheretima 15g, Periostracum Cicadae 12g.

By the method for the Chinese drug preparation tincture of above-mentioned weight portion, carry out in accordance with the following steps:

A, by Herba Hedyotidis Diffusae 15g, Cortex Dictamni 15g, Radix Notoginseng 15g, Fructus Kochiae 15g, Fructus Cnidii 15g, Rhizoma Coptidis 10-20g, Radix Rehmanniae Preparata 15g, Radix Scutellariae 16g, Radix Et Rhizoma Rhei 12g, Radix Sophorae Flavescentis 10-20g, Radix Stemonae 12g, Flos Lonicerae 12g, Herba Taraxaci 16g, Fructus Forsythiae 16g, Radix Saposhnikoviae 15g, Pheretima 15g, Periostracum Cicadae 12g are prepared into Chinese medicinal powder after mixing and are placed in hermetic container;

B, to the ethanol 400ml that adds 60% in container, the taken amount of ethanol be as the criterion medicated powder can be covered to dipping, ethanol covers medicated powder dipping and fully stirs, and places hypsokinesis in 7 days and goes out the supernatant in container, standby;

C, get after salicylic acid 6g, benzoic acid 11g, supernatant 90ml mix and make medicinal tincture.

In addition the external method of medicinal tincture described in above-described embodiment: smear every day 2 times in affected part.External can make the state of an illness take a turn for the better to some extent for 1 week, and some patients were can be fully recovered for 3 days.

The present invention does clinical observation with 162 routine cases, consequently:

Treatment group 96 example one male's 56 examples, women's 40 examples, age 5-64 year. 2 years 1 Mondays of disease time, average course for the treatment of 2.8 weeks:

Matched group 66 example one male's 36 examples, women's 30 examples, age 6-55 year, 2 years 1 Mondays of disease time, average course for the treatment of 3.4 weeks.

The result of with form, this Linchuan being observed is below done detailed comparison, sees the following form:

Group	Treatment group	Matched group
			Number of cases	96 examples	66 examples
Recovery from illness number of cases	80 examples	33 examples
			Effective number of cases	14 examples	12 examples
Effective number of cases	2 examples	10 examples
			Invalid number of cases	0 example	11 examples
Total effectively number of cases	96 examples	46 examples
			Total effective rate	100％	83.2％

Example 1: the Wang ，Nan ，21Sui， student of Yutian County, suffer from tinea pedis 1 year, very itch unbearably, repeated multiple times application miconazole, Compound Flavescent Sophora and Salicylic Acid Powder, etc. treatment, all do not cure.With the present invention's treatment, recovery from illness in 8 days.

Example 2: Lee, 39 years old, man, people from Ninghe County, Tianjin, suffers from tinea versicolor 1 year, external the present invention, day 3 times, recovery from illness in 3 weeks.

Example 3: Liu ，Nan ，52Sui， people from Yutian County, suffer from tinea cruris 2 months, through multi-treatment, fail to cure, take the present invention outward, day 3 times, recovery from illness in 3 weeks.

Disclosed is above only specific embodiments of the invention, but the present invention is not limited thereto, and the changes that any person skilled in the art can think of, within all should dropping on protection scope of the present invention.

Claims (2)

1. the medicinal tincture for the treatment of dermatomycosis, is characterized in that, described medicinal tincture comprises following component:

Herba Hedyotidis Diffusae 5-15g, Cortex Dictamni 5-15g, Radix Notoginseng 5-15g, the Fructus Kochiae 5-15g, Fructus Cnidii 5-15g, Rhizoma Coptidis 10-20g, Radix Rehmanniae Preparata 5-15g, Radix Scutellariae 4-16g, Radix Et Rhizoma Rhei 6-12g, Radix Sophorae Flavescentis 10-20g, Radix Stemonae 6-12g, Flos Lonicerae 6-12g, Herba Taraxaci 4-16g, Fructus Forsythiae 4-16g, Radix Saposhnikoviae 5-15g, Pheretima 5-15g, Periostracum Cicadae 6-12g.

2. by the method for the Chinese drug preparation tincture of above-mentioned weight portion, carry out in accordance with the following steps:

A, by Herba Hedyotidis Diffusae 5-15g, Cortex Dictamni 5-15g, Radix Notoginseng 5-15g, Fructus Kochiae 5-15g, Fructus Cnidii 5-15g, Rhizoma Coptidis 10-20g, Radix Rehmanniae Preparata 5-15g, Radix Scutellariae 4-16g, Radix Et Rhizoma Rhei 6-12g, Radix Sophorae Flavescentis 10-20g, the Radix Stemonae 6-12g, Flos Lonicerae 6-12g, Herba Taraxaci 4-16g, Fructus Forsythiae 4-16g, Radix Saposhnikoviae 5-15g, Pheretima 5-15g, Periostracum Cicadae 6-12g are prepared into Chinese medicinal powder after mixing and are placed in hermetic container;

B, to the ethanol 300-400ml that adds 60% in container, medicated powder is covered and floods and stir, place hypsokinesis in 7 days and go out the supernatant in container, standby;

C, get after salicylic acid 4-6g, benzoic acid 9-11g, supernatant 80-90ml mix and make medicinal tincture.