CN102680280A - Liquid sampling device - Google Patents
Liquid sampling device Download PDFInfo
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- CN102680280A CN102680280A CN2012101603098A CN201210160309A CN102680280A CN 102680280 A CN102680280 A CN 102680280A CN 2012101603098 A CN2012101603098 A CN 2012101603098A CN 201210160309 A CN201210160309 A CN 201210160309A CN 102680280 A CN102680280 A CN 102680280A
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- peristaltic pump
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Abstract
The invention discloses a liquid sampling device which comprises a liquid infusion container, two or more containers with liquid to be tested, a sampling pipeline, a sampling container, a sampling needle arranged at one end of the sampling pipeline correspondingly, and a peristaltic pump corresponding to the corresponding sampling pipeline, wherein one end of the peristaltic pump is communicated with the container with liquid to be tested, the other end of the peristaltic pump is provided with a liquid infusion pipe connected with the liquid infusion container, and a liquid outlet to be connected with the other end of the sampling pipeline. Compared with the prior art, the liquid sampling device has the beneficial effects that the sampling pipeline is controlled by the peristaltic pump, so that the structure is simple and the control cost is lowered; in addition, a metering gage additionally arranged is used for testing the sampling pipeline and feeding back control on the peristaltic pump, thus objectively realizing automatic alignment on the sampling pipeline and ensuring the sampling accuracy.
Description
Technical field
The present invention relates to a kind of fluid sampling device, the especially a kind of and matching used fluid sampling device of dissolution determination instrument.
Background technology
The sample analysis instrument of on-line monitoring pipeline and liquid in containers is widely used; Realize on-line monitoring to liquid; Matter of utmost importance is will fluid to be measured be collected in the analytical instrument of on-line monitoring, as the quality analysis of industrial circle ultrapure water, urban sewage discharge detect and pharmaceutical field in to the assay determination of drug dissolution etc.Existing sampling system mainly takes the mode of supporting solenoid valve of peristaltic pump or the supporting solenoid valve of syringe pump to come testing sample is taken a sample; But when adopting peristaltic pump system to take a sample; Import pipeline because be provided with different liquid in the detection system usually; And different pipelines often self with resistance be no; And the power that peristaltic pump provides is constant, and will cause thus provides identical power but the sampling result of different pipelines but corresponding deviation can occur with peristaltic pump under the equal time, influences the sampling result precision; Adopt the mode of syringe pump to take a sample, the peristaltic pump sampling that precision is more single can be higher, but supporting solenoid valve controls different pipelines, and the total system complex structure, volume is big, cost is high and safeguard also comparatively difficulty.
Summary of the invention
The present invention provides a kind of simple and effective fluid sampling device for solving the shortcomings and deficiencies described in the above-mentioned background technology.
For realizing above-mentioned purpose; The technical scheme that the present invention adopts is: a kind of device of liquid sampling; Comprise fluid infusion container, two or more liquid container to be measured, sampling line, sampling container, be arranged at the sampling probe of corresponding sampling line one end, the peristaltic pump corresponding with corresponding sampling line; Described peristaltic pump one end is communicated with liquid container to be measured, and the other end is provided with the replenishing line that is connected with the fluid infusion container and the liquid outlet of the sampling line other end to be connected.
As further improvement of the present invention, described sampling line also is provided with two-dimensional motion mechanism and feedback pipe pressure is given the weigher of peristaltic pump control system.Above-mentioned two-dimensional motion mechanism adopts motor, ball-screw respectively, realizes moving forward and backward of liquid outlet and moving up and down of tie point through the rotating of motor is controlled.The liquid container that above-mentioned weigher comprises pressure transducer and is located at the pressure transducer top; The pressure that weigher produces when each pipeline is worked writes down and feeds back to the peristaltic pump control system; Through control system the peristaltic pump sampling value is carried out close-loop feedback control, guaranteed the precision of sampling.
As further improvement of the present invention, a described three-way connection is connected between peristaltic pump, liquid outlet, the replenishing line.
As further improvement of the present invention; Described replenishing line is provided with first retaining valve of the unidirectional inflow peristaltic pump of conducting flow; Described liquid outlet front end and sampling line are respectively equipped with second, third retaining valve; The described second retaining valve conducting flow flows to liquid outlet from peristaltic pump, and described the 3rd retaining valve conducting flow flows into sampling line; Described first, second retaining valve is arranged at the three-way connection rear side.
As further improvement of the present invention, a three-way solenoid valve connects liquid outlet and sampling line
Compared with prior art; The invention has the beneficial effects as follows: with peristaltic pump sampling line is controlled, simple in structure, and reduced and controlled cost; In addition; Through setting up weigher sampling line is detected and the FEEDBACK CONTROL peristaltic pump, objectively realized automatic calibration, guaranteed sampling precision sampling line.
Description of drawings
Below in conjunction with accompanying drawing and embodiment the present invention is further specified
Fig. 1 is an one-piece construction synoptic diagram of the present invention.
Embodiment
The present invention includes fluid infusion container 8, two or more liquid container to be measured 9, sampling line, sampling container 7, be arranged at the sampling probe 1 of corresponding sampling line one end, the peristaltic pump 2 corresponding with corresponding sampling line; Peristaltic pump 2 one ends are communicated with liquid container 9 to be measured; The other end is provided with the replenishing line that is connected with fluid infusion container 8 and liquid outlet 10, one three-way connections of the sampling line other end to be connected are connected between peristaltic pump 2, liquid outlet 10, the replenishing line.
Sampling line also is provided with two-dimensional motion mechanism and feedback pipe pressure is given the weigher 11 of peristaltic pump 2 control system, the liquid container 12 that weigher 11 comprises pressure transducer and is located at the pressure transducer top.
Replenishing line is provided with first retaining valve 3 of the unidirectional inflow peristaltic pump 2 of conducting flow; Liquid outlet 10 front ends, and sampling line be respectively equipped with second, third retaining valve 4,6; Second retaining valve, 4 conducting flows flow to liquid outlet 10 from peristaltic pump 2, and described the 3rd retaining valve 6 conducting flows flow into sampling line; First, second retaining valve 3,4 is arranged at the three-way connection rear side.
Fluid sampling device is divided into following several stages work:
Phase one: preparatory stage
Sampling probe 1 is in a position, and peristaltic pump 2 turns round counterclockwise, draws the fluid infusion solvent, makes the fluid infusion solvent be full of the pipeline between fluid infusion container and the peristaltic pump through first retaining valve 3, peristaltic pump 2; System starts working, and moves the tie point 5 or the liquid outlet 10 of sampling line, and liquid outlet 10 is connected with tie point 5.This moment, peristaltic pump 2 turned round clockwise; Draw the testing liquid of 9 li of liquid containers to be measured; Make testing liquid be full of whole pipe through peristaltic pump 2, second retaining valve 4, tie point 5, the 3rd retaining valve 6; And form the loop and finally get back in the liquid container to be measured, this moment, sampling system was full of solvent, and the sampling line air is thoroughly discharged.
Subordinate phase: calibration phase
Before the sampling; Like the automatic timing of needs; Can solution to be measured be introduced in the sampling line through being located at the liquid container 12 of pressure transducer 11 tops, the pressure that produce when weigher is through 11 pairs of each pipeline work of pressure transducer this moment writes down and feeds back to the peristaltic pump control system; Use through control system the peristaltic pump sampling value is controlled, guaranteed the precision of sampling.
Phase III: sample phase
Before the formal sampling, peristaltic pump 2 is turned round counterclockwise, the pressure that produces in the discharge conduit flow duct moves tie point 5 or liquid outlet 10 then, and liquid outlet 10 and tie point 5 are broken off.Consider and break off between liquid outlet 10 and the tie point 5 and be connected the operational complicacy that causes; At this moment; Also can connect liquid outlet 10, sampling line and tie point 5, so can under the condition of not breaking off tie point and liquid outlet, carry out direct sample through setting up a three-way solenoid valve.During sampling; The control system of the peristaltic pump 2 that disposes respectively through every sampling line is carried out signal controlling to the running accuracy of peristaltic pump; This moment, peristaltic pump 2 turned round clockwise; From liquid container 9 to be measured, extract a bit quantitative liquid to be measured,, testing liquid is incorporated in the sampling container 7 through retaining valve 4.
Stage: fluid infusion stage
For guaranteeing that the total amount of liquid in the liquid container 9 to be measured does not reduce, need solution, at this moment to additional in the testing container 9 and sample flow equivalent; Peristaltic pump 2 antiports; Through retaining valve 3, peristaltic pump 2 takes out from fluid infusion container 8 in solvent to the liquid container 9 to be measured of equivalent.
Five-stage: return the liquid stage
The position of sampling probe 1 rises to a from b; Move tie point 5 or liquid outlet 10; Liquid outlet 10 is connected with tie point 5, solution is introduced in the liquid container 9 to be measured, at this moment through peristaltic pump 2, retaining valve 4, tie point 5, the retaining valve 6 of running clockwise; Peristaltic pump 2 runnings make and are full of air in the pipeline, for following sub-sampling is prepared.
Claims (6)
1. fluid sampling device; It is characterized in that: comprise fluid infusion container (8), two or more liquid container to be measured (9), sampling line, sampling container (7), be arranged at the sampling probe (1) of corresponding sampling line one end, the peristaltic pump (2) corresponding with corresponding sampling line; Described peristaltic pump (2) one ends are communicated with liquid container to be measured (9), and the other end is provided with the replenishing line that is connected with fluid infusion container (8) and the liquid outlet (10) of the sampling line other end to be connected.
2. fluid sampling device as claimed in claim 1 is characterized in that: described sampling line also is provided with two-dimensional motion mechanism and feedback pipe pressure is given the weigher (11) of peristaltic pump (2) control system.
3. fluid sampling device as claimed in claim 2 is characterized in that: the liquid container (12) that described weigher (11) comprises pressure transducer and is located at the pressure transducer top.
4. fluid sampling device as claimed in claim 1 is characterized in that: a described three-way connection is connected between peristaltic pump (2), liquid outlet (10), the replenishing line.
5. like claim 1 or 4 described fluid sampling devices; It is characterized in that: described replenishing line is provided with first retaining valve (3) of the unidirectional inflow peristaltic pump of conducting flow (2); Described liquid outlet (10) front end, and sampling line be respectively equipped with second, third retaining valve (4,6); Described second retaining valve (4) conducting flow flows to liquid outlet (10) from peristaltic pump (2), and described the 3rd retaining valve (6) conducting flow flows into sampling line; Described first, second retaining valve (3,4) is arranged at the three-way connection rear side.
6. fluid sampling device as claimed in claim 1 is characterized in that: a described three-way solenoid valve connects liquid outlet (10) and sampling line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210160309.8A CN102680280B (en) | 2012-05-16 | 2012-05-16 | Liquid sampling device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210160309.8A CN102680280B (en) | 2012-05-16 | 2012-05-16 | Liquid sampling device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102680280A true CN102680280A (en) | 2012-09-19 |
| CN102680280B CN102680280B (en) | 2015-02-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210160309.8A Active CN102680280B (en) | 2012-05-16 | 2012-05-16 | Liquid sampling device |
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| Country | Link |
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| CN (1) | CN102680280B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103197620A (en) * | 2013-02-28 | 2013-07-10 | 重庆大学 | Precise sampling control system |
| CN104964852A (en) * | 2015-07-10 | 2015-10-07 | 河海大学 | Annular sealed tank sampling device with automatic compensation function and sampling method |
| CN108827715A (en) * | 2018-08-28 | 2018-11-16 | 福建龙岩龙瑆医药科技有限公司 | A kind of fluid sampling device |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2044954A (en) * | 1979-03-21 | 1980-10-22 | Lilly Industries Ltd | Control of fluid sampling apparatus |
| CN2373787Y (en) * | 1999-05-15 | 2000-04-12 | 刘文涛 | Automatic sampler for polarograph |
| US20040168529A1 (en) * | 2003-03-01 | 2004-09-02 | Carlson Eric D. | Methods and systems for dissolution testing |
| CN102313795A (en) * | 2011-07-28 | 2012-01-11 | 广东医学院 | Intelligent numerical control bionic drug dissolubility tester |
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2012
- 2012-05-16 CN CN201210160309.8A patent/CN102680280B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2044954A (en) * | 1979-03-21 | 1980-10-22 | Lilly Industries Ltd | Control of fluid sampling apparatus |
| CN2373787Y (en) * | 1999-05-15 | 2000-04-12 | 刘文涛 | Automatic sampler for polarograph |
| US20040168529A1 (en) * | 2003-03-01 | 2004-09-02 | Carlson Eric D. | Methods and systems for dissolution testing |
| CN102313795A (en) * | 2011-07-28 | 2012-01-11 | 广东医学院 | Intelligent numerical control bionic drug dissolubility tester |
Non-Patent Citations (2)
| Title |
|---|
| R.A. HILL AND B.G. SNIDER: "A widely applicable automated sampling apparatus for dissolution testing", 《INTERNATIONAL JOURNAL OF PHARMACEUTICS》 * |
| 齐婉玉 等: "用于药品溶出度/释放度检定的新型自动取样系统", 《现代仪器》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103197620A (en) * | 2013-02-28 | 2013-07-10 | 重庆大学 | Precise sampling control system |
| CN104964852A (en) * | 2015-07-10 | 2015-10-07 | 河海大学 | Annular sealed tank sampling device with automatic compensation function and sampling method |
| CN108827715A (en) * | 2018-08-28 | 2018-11-16 | 福建龙岩龙瑆医药科技有限公司 | A kind of fluid sampling device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102680280B (en) | 2015-02-25 |
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| C14 | Grant of patent or utility model | ||
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Owner name: ZHEJIANG TAILIN BIOTECHNOLOGY CO., LTD. Free format text: FORMER NAME: HANGZHOU TAILIN BIOTECHNOLOGY EQUIPMENT CO., LTD. |
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Address after: 310052 Binjiang District, Zhejiang, South Ring Road, No. 2930, No. Patentee after: ZHEJIANG TAILIN BIOENGINEERING Co.,Ltd. Address before: The South Ring Road of Binjiang District Hangzhou city Zhejiang province 310052 No. 2930 Hangzhou Tailin Bioengineering Equipment Co. Ltd. Patentee before: Hangzhou Tailin Bioengineering Equipments Co.,Ltd. |
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Effective date of registration: 20230515 Address after: Building 2, 2nd Floor, No. 2930 South Ring Road, Puyan Street, Binjiang District, Hangzhou City, Zhejiang Province, 310000 Patentee after: Zhejiang Tailin Analytical Instrument Co.,Ltd. Address before: 310052 No. 2930 South Ring Road, Hangzhou, Zhejiang, Binjiang District Patentee before: ZHEJIANG TAILIN BIOENGINEERING Co.,Ltd. |