CN102670870B - 一种治疗小儿急性化脓扁桃体炎的中草药制剂 - Google Patents
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Abstract
本发明公开了一种治疗小儿急性化脓扁桃体炎的中草药制剂。中医认为小儿急性化脓扁桃体炎的病因为风热邪毒从口鼻而入侵犯肺胃两经，邪毒熏蒸于咽喉遂成本病。故本发明选择具有清泻肺胃之热，解毒消肿的中药胆木、玻璃草根、蛾药、山白菊、金银花、小叶金花草、射干、牛蒡子、柴胡、山豆根、天花粉、太子参、生甘草制成汤剂，经我院临床试验，治愈率为66.67％，总有效率为96.67％，均优于对照组，而且治疗成本低，副作用小。
Description
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗小儿急性化脓扁桃体炎的中草药制剂。
背景技术
急性化脓性扁桃体炎是腭扁桃体的急性非特异性炎症，是小儿常见的咽部疾病，具有反复发作、极易引起局部及全身并发症等特点。据流行病学调查显示，随着社会发展及人们生活环境等因素的改变，小儿急性化脓性扁桃体炎的发病率呈现出有增无减的态势。由于小儿急性化脓性扁桃体炎患儿常常以发热、咽喉痛、吞咽困难为主要临床表现，但严重者可出现急性肾小球肾炎、心肌炎等并发症而对患儿生命安全构成极大威胁，同时加之抗生素滥用等因素影响，西医治疗小儿急性化脓性扁桃体炎治疗效果明显下降且复发率较高。
发明内容
本发明的目的是提供一种治疗小儿急性化脓扁桃体炎的中草药制剂。小儿由于身体抵抗力低，加上受凉感冒，就会使扁桃体抵抗细菌的能力减弱，从而导致口腔、咽部、鼻腔以及外界的细菌侵入扁桃体、发生炎症。严重者扁桃体红肿化脓，形成化脓性扁桃体炎，久治不愈可转成慢性扁桃体炎，容易引起肾炎、心脏病、风湿等全身性疾病。中医认为小儿急性化脓扁桃体炎的病因为风热邪毒从口鼻而入侵犯肺胃两经，邪毒熏蒸于咽喉遂成本病。故中医治疗采取清泻肺胃之热，重用解毒之法。
本发明的目的是通过以下技术方案实现的，该治疗小儿急性化脓扁桃体炎的中草药制剂由以下重量份中药制成：胆木6-9份、玻璃草根6-9份、蛾药6-9份、山白菊12-15份、金银花12-15份、小叶金花草12-15份、射干10-12份、牛蒡子10-12份、柴胡10-12份、山豆根10-13份、天花粉6-8份、太子参6-8份、生甘草5-7份。
优选的，该治疗小儿急性化脓扁桃体炎的中草药制剂由以下重量份的中药制成：胆木7份、玻璃草根7份、蛾药7份、山白菊13份、金银花13份、小叶金花草13份、射干11份、牛蒡子11份、柴胡11份、山豆根12份、天花粉7份、太子参7份、生甘6份。
将上药按照传统的制备方法制成汤剂。
方中：胆木：清热解毒、消肿止痛，主治扁桃体炎。
玻璃草根：清热解毒，主治扁桃体炎。
蛾药：清热解毒，消炎止痛，主治扁桃体炎。
山白菊：归心经；清热解毒，疏风解表，凉血止血。
金银花：归肺、心、胃、大肠经；清热解毒，疏散风热。
小叶金花草：归胃，肠，膀胱经；清热利湿，活血止血，解毒消肿。
射干：归肺经；清热解毒，利咽祛痰。
牛蒡子：归肺、胃经；发散风热，解毒透疹，利咽。
柴胡：归心包络、肝、胆、三焦经；疏散退热，疏肝解郁，升举阳气。
山豆根：归肺、胃经；清热解毒，利咽消肿。
天花粉：归肺、胃经；清热生津，消肿排脓。
太子参：入脾、肺经；补益脾肺，益气生津。
生甘草：具有缓急止痛，清热解毒，补脾益气，祛痰止咳，调和诸药。
临床资料
1、一般资料 一般资料：选取2010年3月～2010年12月来我院就诊符合《临床儿科学》有关急性化脓性扁桃体炎诊断标准的患儿120例，对存在以下情况者给予排除：①心、肝、脑、肾及肺等重要器官存在严重疾病的患儿；②因其他原因引起扁桃体化脓的患儿；③未按照本次研究规定执行的患儿。同时查阅120例研究对象病历资料显示其中男78例，女42例，平均年龄(5.30±1.35)岁，扁桃体Ⅰ度肿大者12例、Ⅱ度肿大者100例、Ⅲ度肿大者8例；所有患儿均存在不同程度发热、咽痛、吞咽困难、扁桃体出现充血和肿大及黄白脓点等临床表现。两组患儿在年龄、性别、扁桃体情况等方面比较，差异无统计学意义(P＞0.05)，具有可比性。
2、治疗方法 治疗组服用本发明所述的中草药汤剂，每日1剂，早晚分服2次。对照组：给予青霉素10万U/(kg·次)，2次/天。两组均5天为一个疗程，治疗两个疗程统计疗效。
3、疗效标准 参照国家中医药管理局医政司1994年6月颁布的《中医病证诊断疗效标准》[1]执行。治愈：体温正常，血象正常，咽部症状消失，扁桃体不充血，无脓点。好转：仍有低热，血象接近正常，咽部症状减轻，扁桃体脓点消除。未愈：症状和体征无明显改善。
5、治疗结果 两组治疗两周后疗效比较见表1。
表1 两组治疗两周后疗效比较例(％)
注：与对照组比较P＜0.05。
从表1可以看出，治疗组治愈率为66.67％，对照组为36.67％，存在显著性差异(P＜0.01)；治疗组总有效率为96.67％，对照组为85.00％也具有可比性(P＜0.05)。
具体实施方式
实施例一：称取胆木7g、玻璃草根7g、蛾药7g、山白菊13g、金银花13g、小叶金花草13g、射干11g、牛蒡子11g、柴胡11g、山豆根12g、天花粉7g、太子参7g、生甘草6g制成汤剂，每日1剂，早晚分服2次。
实施例二：称取胆木6g、玻璃草根6g、蛾药6g、山白菊12g、金银花12g、小叶金花草12g、射干10g、牛蒡子10g、柴胡10g、山豆根10g、天花粉6g、太子参6g、生甘草5g制成汤剂，每日1剂，早晚分服2次。
实施例三：称取胆木9g、玻璃草根9g、蛾药9g、山白菊15g、金银花15g、小叶金花草15g、射干12g、牛蒡子12g、柴胡12g、山豆根13g、天花粉8g、太子参8g、生甘草7g制成汤剂，每日1剂，早晚分服2次。
Claims (2)
1.一种治疗小儿急性化脓扁桃体炎的中草药制剂，其特征在于该中草药制剂由以下重量份中药制成：胆木6—9份、玻璃草根6—9份、蛾药6—9份、山白菊12—15份、金银花12—15份、小叶金花草12—15份、射干10-12份、牛蒡子10-12份、柴胡10—12份、山豆根10-13份、天花粉6—8份、太子参6—8份、生甘草5—7份。
2.根据权利要求1所述的一种治疗小儿急性化脓扁桃体炎的中草药制剂，其特征在于该中草药制剂由以下重量份中药制成：胆木7份、玻璃草根7份、蛾药7份、山白菊13份、金银花13份、小叶金花草13份、射干11份、牛蒡子11份、柴胡11份、山豆根12份、天花粉7份、太子参7份、生甘草6份。
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