CN102641405B - 一种治疗小儿急性支气管炎的中药制剂 - Google Patents
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Abstract
本发明公开了一种治疗小儿急性支气管炎的中药制剂。中医认为小儿急性支气管炎，多是由于患儿体质虚弱、内热湿重，加之外感风邪导致痰盛拥塞所致。为此，本发明选择具有抗菌消炎、解痉平喘、以清肺热，化痰祛湿的中药、荠苨、淮通、草贝母、小丁香、黄柏、桔梗、甘草、洋金花、香橼、车前子、茯苓制成汤剂，供患者服用，经我院临床试验，总有效率达到96.0％，治疗效果好，成本低，副作用小，值得临床推广应用。
Description
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗小儿急性支气管炎的中药制剂。
背景技术
小儿急性支气管炎是儿科常见的下呼吸道感染性疾病，常由病毒、肺炎支原体、细菌或合并感染引起，急性支气管炎发病机制为病原体侵入呼吸道后，由于患儿机体抵抗力低下，病原不被局限，炎症向下蔓延至支气管、毛细支气管及肺泡。支气管粘膜炎症水肿导致管腔狭窄，肺泡壁充血水肿增厚，肺泡腔充满炎症渗出物，导致通气和换气功能障碍，患者出现咳喘、咳痰及呼吸困难等症状。目前小儿急性支气管炎治疗以抗感染、抗病毒、退热、止咳化痰、促进啰音吸收为主要措施。近年来由于广泛和不合理应用各种抗生素，使呼吸系统的病原菌多产生不同程度的耐药性，导致患儿的治疗费用增加，治疗时间延长，但疗效并不理想。
发明内容
本发明的目的是提供一种治疗小儿急性支气管炎的中药制剂，中医认为小儿急性支气管炎，多是由于患儿体质虚弱、内热湿重，加之外感风邪导致痰盛拥塞所致。治疗时应当抗菌消炎、解痉平喘、以清肺热，化痰祛湿为主。
本发明的目的是由以下技术方案实现的，该治疗小儿急性支气管炎的中药制剂由以下重量份的中药制成：荠苨7-9份、淮通10-13份、草贝母7-9份、小丁香10-12份、黄柏10-13份、桔梗7-9份、甘草3-6份、洋金花7-10份、香橼7-9份、车前子6-9份、茯苓5-7份。
优选的，治疗小儿急性支气管炎中药制剂由以下重量份的中药制成：荠苨8份、淮通12份、草贝母8份、小丁香11份、黄柏11份、桔梗8份、甘草5份、洋金花9份、香橼8份、车前子7份、茯苓6份。
上述中药按传统的方法制成汤剂。
方中：荠苨：归肺，脾经；润燥化痰，清热解毒；治疗急性支气管炎。
淮通：入心、肾、膀胱、小肠经；清热除湿，排脓止痛。
草贝母：平喘止咳，镇痛抗癌；治支气管炎。
小丁香：清热解毒，祛风止痛；治疮疖痈肿，小儿支气管炎。
黄柏：归肾、膀胱经；清热燥湿，泻火解毒，退热除蒸。
甘草：补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。
桔梗：入肺经；宣肺祛痰，利咽排脓。
洋金花：归肺、肝经；平喘止咳，镇痛止痉。
香橼：入肝、肺、脾经；疏肝解郁，理气宽中，化痰止咳。
车前子：入肾、膀胱、肝肺经；利尿通淋，渗湿止泻，清肝明目，清肺化痰。
茯苓：归心、肺、脾、肾经；利水渗湿，健脾安神。
临床资料
1、一般资料本组190例均为2009年5月～11月期间在我科住院病例，男96例，女94例；年龄最小1.5岁，最大11岁，临床症状均为发热、咳嗽、咳痰，无呼吸困难和紫钳。查体双肺呼吸音粗，有痰鸣音或(和)喘鸣音，均符合急性支气管炎判断标准，其中发热184例，咳嗽190例，伴有气喘30例，随机分为两组，治疗组124例，对照组66例，两组病情、性别、年龄分布均无明显差异。
2、治疗方法治疗组服用本发明所述的中药汤剂，每日早、晚各服1次，7天为1个疗程。共服用两个疗程。对照组用头孢唑啉100mg/kg.d加入5％或10％mg/kg.d葡萄糖注射液100～250ml中静滴，7天为1个疗程，共两个疗程。
3、疗效标准根据卫生部颁布的《抗菌药物临床研究指导原则》按痊愈、显效、有效、无效评定。(1)痊愈：治疗3天，体温正常，咳嗽症状消失，双肺痰呜音，喘鸣音消失，食欲恢复；(2)显效：体温正常，咳嗽症状明显减轻，双肺痰呜音、喘鸣音明显减少、食欲较前恢复；(3)有效：体温下降，咳嗽症状减轻，双肺音减少，但食欲仍差；(4)无效：发热、咳嗽等主要症状，疗程超过3天而无明显改善，体温下降＜1℃，病情加重或兼有其他全身症状。
4、治疗结果两组均治疗两个疗程后症状消失状况见表1。
表1 症状消失统计
两组均治疗两个疗程后，统计治疗结果见表2。
表2 近期治疗效果统计
从表2中可以看出，治疗组的总有效率96.0％；对照组的总有效率为81.8％。具有统计学意义
具体实施方式
实施例一：称取荠苨8g、淮通12g、草贝母8g、小丁香11g、黄柏11g、桔梗8g、甘草5g、洋金花9g、香橼8g、车前子7g、茯苓6g，用水煎煮半小时后取汁，早、晚各服1次，7天为1个疗程，连续服用两个疗程。
实施例二：称取荠苨7g、淮通10g、草贝母7g、小丁香10g、黄柏10g、桔梗7g、甘草3g、洋金花7g、香橼7g、车前子6g、茯苓5g，用水煎煮半小时后取汁，早、晚各服1次，7天为1个疗程，连续服用两个疗程。
实施例三：称取荠苨9g、淮通13g、草贝母9g、小丁香12g、黄柏13g、桔梗9g、甘草6g、洋金花10g、香橼9g、车前子9g、茯苓7g，用水煎煮半小时后取汁，早、晚各服1次，7天为1个疗程，连续服用两个疗程。
Claims (2)
1.一种治疗小儿急性支气管炎的中药制剂，其特征在于该中药制剂由以下重量份的中药制成：荠苨7-9份、淮通10-13份、草贝母7-9份、小丁香10-12份、黄柏10-13份、桔梗7-9份、甘草3-6份、洋金花7-10份、香橼7-9份、车前子6-9份、茯苓5-7份。
2.根据权利要求1所述的一种治疗小儿急性支气管炎的中药制剂，其特征在于该中药制剂由以下重量份的中药制成：荠苨8份、淮通12份、草贝母8份、小丁香11份、黄柏11份、桔梗8份、甘草5份、洋金花9份、香橼8份、车前子7份、茯苓6份。
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