CN102666523A - 用于治疗癌症的大环内酯衍生物 - Google Patents
用于治疗癌症的大环内酯衍生物 Download PDFInfo
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- CN102666523A CN102666523A CN201080057594XA CN201080057594A CN102666523A CN 102666523 A CN102666523 A CN 102666523A CN 201080057594X A CN201080057594X A CN 201080057594XA CN 201080057594 A CN201080057594 A CN 201080057594A CN 102666523 A CN102666523 A CN 102666523A
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- 230000004797 therapeutic response Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 125000001425 triazolyl group Chemical group 0.000 description 1
- RTKIYFITIVXBLE-QEQCGCAPSA-N trichostatin A Chemical compound ONC(=O)/C=C/C(/C)=C/[C@@H](C)C(=O)C1=CC=C(N(C)C)C=C1 RTKIYFITIVXBLE-QEQCGCAPSA-N 0.000 description 1
- 229950002929 trinitrophenol Drugs 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical class OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 229960000281 trometamol Drugs 0.000 description 1
- 230000004222 uncontrolled growth Effects 0.000 description 1
- 241001446247 uncultured actinomycete Species 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26185609P | 2009-11-17 | 2009-11-17 | |
| US61/261,856 | 2009-11-17 | ||
| PCT/IB2010/055161 WO2011061666A1 (en) | 2009-11-17 | 2010-11-15 | Macrocyclic lactone derivatives for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102666523A true CN102666523A (zh) | 2012-09-12 |
Family
ID=43566625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080057594XA Pending CN102666523A (zh) | 2009-11-17 | 2010-11-15 | 用于治疗癌症的大环内酯衍生物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8637683B2 (enExample) |
| EP (1) | EP2501689A1 (enExample) |
| JP (1) | JP2013510899A (enExample) |
| KR (1) | KR20120092677A (enExample) |
| CN (1) | CN102666523A (enExample) |
| AU (1) | AU2010320557A1 (enExample) |
| CA (1) | CA2792198A1 (enExample) |
| IL (1) | IL219807A0 (enExample) |
| MX (1) | MX2012005618A (enExample) |
| NZ (1) | NZ600660A (enExample) |
| RU (1) | RU2012124817A (enExample) |
| WO (1) | WO2011061666A1 (enExample) |
| ZA (1) | ZA201204488B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013510900A (ja) * | 2009-11-17 | 2013-03-28 | ピラマル・ライフ・サイエンシーズ・リミテッド | 炎症性疾患治療のための大環状ラクトン誘導体の使用 |
| WO2014118740A1 (en) * | 2013-02-04 | 2014-08-07 | Piramal Enterprises Limited | Macrocyclic lactone derivatives and uses thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997023475A1 (en) * | 1995-12-22 | 1997-07-03 | Astra Aktiebolag | Active compounds ii |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013510900A (ja) * | 2009-11-17 | 2013-03-28 | ピラマル・ライフ・サイエンシーズ・リミテッド | 炎症性疾患治療のための大環状ラクトン誘導体の使用 |
-
2010
- 2010-11-15 AU AU2010320557A patent/AU2010320557A1/en not_active Abandoned
- 2010-11-15 US US13/510,458 patent/US8637683B2/en not_active Expired - Fee Related
- 2010-11-15 JP JP2012539450A patent/JP2013510899A/ja active Pending
- 2010-11-15 CN CN201080057594XA patent/CN102666523A/zh active Pending
- 2010-11-15 NZ NZ600660A patent/NZ600660A/en not_active IP Right Cessation
- 2010-11-15 EP EP10798188A patent/EP2501689A1/en not_active Withdrawn
- 2010-11-15 MX MX2012005618A patent/MX2012005618A/es not_active Application Discontinuation
- 2010-11-15 CA CA2792198A patent/CA2792198A1/en not_active Abandoned
- 2010-11-15 RU RU2012124817/04A patent/RU2012124817A/ru not_active Application Discontinuation
- 2010-11-15 WO PCT/IB2010/055161 patent/WO2011061666A1/en not_active Ceased
- 2010-11-15 KR KR1020127015787A patent/KR20120092677A/ko not_active Withdrawn
-
2012
- 2012-05-15 IL IL219807A patent/IL219807A0/en unknown
- 2012-06-18 ZA ZA2012/04488A patent/ZA201204488B/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997023475A1 (en) * | 1995-12-22 | 1997-07-03 | Astra Aktiebolag | Active compounds ii |
Non-Patent Citations (1)
| Title |
|---|
| HARUYASU KINASHI, ET AL.: "ALKALINE DEGRADATION PRODUCTS OF CONCANAMYCIN A", 《TETRAHEDRON LETTERS》, vol. 22, no. 39, 31 December 1981 (1981-12-31), pages 3857 - 3860, XP002630807, DOI: doi:10.1016/S0040-4039(01)91328-0 * |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201204488B (en) | 2014-08-27 |
| IL219807A0 (en) | 2012-07-31 |
| WO2011061666A1 (en) | 2011-05-26 |
| US8637683B2 (en) | 2014-01-28 |
| JP2013510899A (ja) | 2013-03-28 |
| US20120245183A1 (en) | 2012-09-27 |
| NZ600660A (en) | 2014-02-28 |
| AU2010320557A1 (en) | 2012-07-05 |
| MX2012005618A (es) | 2012-08-15 |
| RU2012124817A (ru) | 2013-12-27 |
| EP2501689A1 (en) | 2012-09-26 |
| CA2792198A1 (en) | 2011-05-26 |
| KR20120092677A (ko) | 2012-08-21 |
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