CN102656464A - 具有改进混合的分析方法 - Google Patents

具有改进混合的分析方法 Download PDF

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Publication number
CN102656464A
CN102656464A CN2010800587504A CN201080058750A CN102656464A CN 102656464 A CN102656464 A CN 102656464A CN 2010800587504 A CN2010800587504 A CN 2010800587504A CN 201080058750 A CN201080058750 A CN 201080058750A CN 102656464 A CN102656464 A CN 102656464A
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CN
China
Prior art keywords
flow cell
sample
flow
solution
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800587504A
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English (en)
Chinese (zh)
Inventor
O.延森
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Cytiva Sweden AB
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GE Healthcare Bio Sciences AB
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Filing date
Publication date
Application filed by GE Healthcare Bio Sciences AB filed Critical GE Healthcare Bio Sciences AB
Publication of CN102656464A publication Critical patent/CN102656464A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
    • B01F33/3022—Micromixers the materials to be mixed flowing in the form of droplets the components being formed by independent droplets which are alternated, the mixing of the components being achieved by diffusion between droplets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN2010800587504A 2009-12-22 2010-12-21 具有改进混合的分析方法 Pending CN102656464A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0951004 2009-12-22
SE0951004-1 2009-12-22
PCT/SE2010/051446 WO2011078777A1 (en) 2009-12-22 2010-12-21 Method of analysis with improved mixing

Publications (1)

Publication Number Publication Date
CN102656464A true CN102656464A (zh) 2012-09-05

Family

ID=44196034

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800587504A Pending CN102656464A (zh) 2009-12-22 2010-12-21 具有改进混合的分析方法

Country Status (5)

Country Link
US (1) US20120264233A1 (enExample)
EP (1) EP2517024A4 (enExample)
JP (1) JP2013515260A (enExample)
CN (1) CN102656464A (enExample)
WO (1) WO2011078777A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105388313A (zh) * 2015-10-27 2016-03-09 北京中科紫鑫科技有限责任公司 一种dna测序仪的试剂液流控制装置
CN108027369A (zh) * 2015-09-25 2018-05-11 通用电气健康护理生物科学股份公司 生物传感器及其用途
CN108226552A (zh) * 2017-04-01 2018-06-29 北京凯因孚生物科技有限公司 一种测量微量样品光学特性的全自动高通量批处理仪器
CN108449963A (zh) * 2015-07-10 2018-08-24 帕尔公司 单次注射竞争分析

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2761295B1 (en) * 2011-09-30 2016-02-10 GE Healthcare Bio-Sciences AB Multi-channel flowcell
SI3030645T1 (sl) * 2013-08-08 2023-03-31 Illumina, Inc. Fluidni sistem za dovajanje reagenta v pretočno celico
EP3213071B1 (en) * 2014-10-30 2019-07-10 GE Healthcare Bio-Sciences AB Method to determine solvent correction curves
DE112015005746B4 (de) * 2015-01-26 2022-12-22 Hitachi High-Tech Corporation Optische Analysenvorrichtung
EP3112869A1 (en) * 2015-06-30 2017-01-04 IMEC vzw Sensor device
GB201614773D0 (en) 2016-09-01 2016-10-19 Ge Healthcare Bio Sciences Ab Stepped merged injection for surface plasmon resonance assays
GB201705280D0 (en) 2017-03-31 2017-05-17 Ge Healthcare Bio Sciences Ab Methods for preparing a dilution series
CN208060444U (zh) * 2017-06-14 2018-11-06 中国科学院过程工程研究所 一种可移动的具有双梯度调节功能的流动相控制系统
JP2019152666A (ja) * 2018-03-02 2019-09-12 富士レビオ株式会社 ジカウイルスを検出する方法及びキット
US11298701B2 (en) 2018-11-26 2022-04-12 King Instrumentation Technologies Microtiter plate mixing control system
US12303849B2 (en) * 2021-06-09 2025-05-20 Revvity Health Sciences, Inc. Mixing liquids using an automated liquid handling system

Citations (4)

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WO2004109284A1 (en) * 2003-06-06 2004-12-16 Biacore Ab Method and system for determination of molecular interaction parameters
WO2004109295A1 (en) * 2003-06-06 2004-12-16 Biacore Ab Method and apparatus for characterization of interactions
US20060289059A1 (en) * 2005-04-28 2006-12-28 Krylov Sergey N Method for mixing inside a capillary and devices for achieving same
CN101583872A (zh) * 2006-09-14 2009-11-18 通用电气健康护理生物科学股份公司 测定待分析物浓度的方法

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SE8804074D0 (sv) * 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
US5861254A (en) * 1997-01-31 1999-01-19 Nexstar Pharmaceuticals, Inc. Flow cell SELEX
US5395587A (en) * 1993-07-06 1995-03-07 Smithkline Beecham Corporation Surface plasmon resonance detector having collector for eluted ligate
US20040028559A1 (en) * 2001-11-06 2004-02-12 Peter Schuck Sample delivery system with laminar mixing for microvolume biosensing
JP2005516220A (ja) * 2002-01-25 2005-06-02 イノベイダイン・テクノロジーズ・インコーポレーテッド 低容量かつ非接触な液体の分注方法
JP2004077387A (ja) * 2002-08-21 2004-03-11 Mitsubishi Heavy Ind Ltd タンパク質検出方法及びタンパク質検出装置
US7563410B2 (en) * 2004-10-19 2009-07-21 Agilent Technologies, Inc. Solid phase extraction apparatus and method
US8980625B2 (en) * 2006-02-24 2015-03-17 National Food Research Institute Cell culture plate and method of manufacturing the same
US8263415B2 (en) * 2006-09-14 2012-09-11 Ge Healthcare Bio-Sciences Ab Method of determining analyte concentration
US20120009591A1 (en) * 2009-03-20 2012-01-12 Ewa Pol Method for detection of an enzyme-substrate reaction

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004109284A1 (en) * 2003-06-06 2004-12-16 Biacore Ab Method and system for determination of molecular interaction parameters
WO2004109295A1 (en) * 2003-06-06 2004-12-16 Biacore Ab Method and apparatus for characterization of interactions
US20060289059A1 (en) * 2005-04-28 2006-12-28 Krylov Sergey N Method for mixing inside a capillary and devices for achieving same
CN101583872A (zh) * 2006-09-14 2009-11-18 通用电气健康护理生物科学股份公司 测定待分析物浓度的方法

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108449963A (zh) * 2015-07-10 2018-08-24 帕尔公司 单次注射竞争分析
CN108449963B (zh) * 2015-07-10 2021-01-05 赛多利斯生物分析仪器股份有限公司 单次注射竞争分析
CN108027369A (zh) * 2015-09-25 2018-05-11 通用电气健康护理生物科学股份公司 生物传感器及其用途
US11255851B2 (en) 2015-09-25 2022-02-22 Cytiva Sweden Ab Method and system for evaluation of an interaction between an analyte and a ligand using a biosensor
CN105388313A (zh) * 2015-10-27 2016-03-09 北京中科紫鑫科技有限责任公司 一种dna测序仪的试剂液流控制装置
CN105388313B (zh) * 2015-10-27 2017-11-14 北京中科紫鑫科技有限责任公司 一种dna测序仪的试剂液流控制装置
CN108226552A (zh) * 2017-04-01 2018-06-29 北京凯因孚生物科技有限公司 一种测量微量样品光学特性的全自动高通量批处理仪器

Also Published As

Publication number Publication date
EP2517024A4 (en) 2013-11-06
EP2517024A1 (en) 2012-10-31
WO2011078777A1 (en) 2011-06-30
US20120264233A1 (en) 2012-10-18
JP2013515260A (ja) 2013-05-02

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Application publication date: 20120905