CN102648958B - Traditional Chinese medicine enema for treating acute upper respiratory infections of children - Google Patents

Abstract

The invention discloses a traditional Chinese medicine enema for treating acute upper respiratory infections of children. The Chinese medicine believes that most acute upper respiratory tract infection causative agents are viruses, and also can be complicated by bacterial infection; and aetiological agents are mainly tender viscera, thin skin, weakened external health, invasion of the wind evil to cause cold. The enema is prepared by the following traditional Chinese medicines: wrightia leaf, ilex pubescens, ephedra, schizonepeta, passiflora foetida, chrysanthemum, radix bupleuri, subprostrate sophora, fritillaria taipaiensis, nandina, platycodon grandiflorum, orange peel and mangnolia officinalis, which have the functions of dispelling wind, relieving exterior syndrome, freeing lung, relieving asthma, clearing heat, removing toxicity, regulating vital energy and tonifying spleen. Through clinical test, the total effective rate is 95.4 percent, which is obviously superior to a controlgroup, the treating cost is low, the drug administration is convenient, and the enema has no side effect, and is worthy of being widely popularized and applied in clinic.

Description

A kind of herbal enema agent for the treatment of infantile acute upper respiratory infection

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of herbal enema agent for the treatment of infantile acute upper respiratory infection.

Background technology

Acute upper respiratory tract infection is common disease in children, frequently-occurring disease.90% is viral infection in the cause of disease, present clinical no specific drug treatment.Generally use antibiotic therapy clinically, so that significantly improved antimicrobial resistance in recent years.Chinese medicine is evident in efficacy, but the administration difficulty, children's should not accept.

Enema is that drug decocting is become the medicinal liquid retention enema, not only solved the problem of medication in children difficulty, and because rectally absorbs abundant, effect rapidly, the medicine per rectum directly enters systemic circulation after being absorbed into blood, reduced the destruction of liver to medicine, improved blood drug level, avoided simultaneously because of oral administration gastric acid and pepsin influence and the drug-induced gastrointestinal reaction to medicine, therefore, rectally have that curative effect is rapid, side effect is little, easy to use, keep strong point such as Chinese medicine traditional decoction characteristics.

Summary of the invention

The purpose of this invention is to provide a kind of herbal enema agent for the treatment of infantile acute upper respiratory infection.Motherland's medical science is thought acute upper respiratory infection, is the acute inflammation of the nose that caused by various pathogen, pharynx, throat, and pathogen mostly is virus, also can concurrent bacterial infection, pathogenic factor is tender and lovely mainly due to children's's internal organs, and skin is dredged thin, weakened defensive QI, cold warm in addition can not self-regulated, be easy to being invaded by exogenous pathogen, weather cataclysm during Chang Yinsi, cold and hot not normal, ailment said due to cold or exposure is taken advantage of a weak point in opponent's defence and is attacked, and the visitor defends in lung, cause impaired depurative descending of lung QI, battalion defends and becomes estranged and cause flu; The total Therapeutic Principle of the traditional Chinese medical science is dispelling wind to relieve the exterior syndrome or relieving the exterior syndrome with drugs of pungent in flavor and warm in nature, relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, eliminating summer-heat from the exterior, hold under the arm expectorant then respectful lung reduce phlegm, hold the then dyspepsia and intestinal stasis relieving that stagnates under the arm, hold frightened then heat clearing away arresting convulsion under the arm.The employing method is all followed above principle determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.

The objective of the invention is to be achieved through the following technical solutions, the herbal enema agent of this treatment youngster acute upper respiratory tract infection is made by following parts by weight of Chinese traditional medicine: Folium wrightiae pubescentis 10-13 part Radix Ilicis Pubescentis 6-9 part, Herba Ephedrae 6-9 part, Herba Schizonepetae 7-10 part, Herba Passiflorae Foetidae 7-10 part, Flos Chrysanthemi 5-8 part, Radix Bupleuri 10-12 part, Radix Sophorae Tonkinensis 5-8 part, Bulbus Fritillariae taipaiensis 7-10 part, nandina 5-7 part, Radix Platycodonis 5-8 part, Pericarpium Citri tangerinae 6-8 part, Cortex Magnoliae Officinalis 10-12 part.

Preferably, the herbal enema agent of this treatment infantile acute upper respiratory infection is made by following parts by weight of Chinese traditional medicine: 12 parts of Folium wrightiae pubescentiss, 8 parts of Radix Ilicis Pubescentiss, 8 parts in Herba Ephedrae, 9 parts of Herba Schizonepetae, 8 parts of Herba Passiflorae Foetidaes, 7 parts of Flos Chrysanthemis, 11 parts of Radix Bupleuri, 7 parts of Radix Sophorae Tonkinensiss, 8 parts of Bulbus Fritillariae taipaiensiss, 6 parts of nandinas, 7 parts of Radix Platycodoniss, 6 parts of Pericarpium Citri tangerinaes, 11 parts of Cortex Magnoliae Officinalis.

The preparation method of this herbal enema agent: get Folium wrightiae pubescentis 12g, Radix Ilicis Pubescentis 8g, Herba Ephedrae 8g, Herba Schizonepetae 9g, Herba Passiflorae Foetidae 8g, Flos Chrysanthemi 7g, Radix Bupleuri 11g, Radix Sophorae Tonkinensis 7g, Bulbus Fritillariae taipaiensis 8g, nandina 6g, Radix Platycodonis 7g, Pericarpium Citri tangerinae 6g, Cortex Magnoliae Officinalis 11g.Earlier soak 15～20min in cold water, the reuse big fire is boiled, the 10～20min that simmers in water at last, and fried one-tenth 200ml medicinal liquid is standby.

In the side: Folium wrightiae pubescentis is controlled acute inflammation and is infected; Radix Ilicis Pubescentis, Herba Ephedrae, Herba Schizonepetae relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema; Flos Chrysanthemi, Radix Bupleuri dispelling wind and heat pathogens, heat-clearing and toxic substances removing, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang; Herba Passiflorae Foetidae, Radix Sophorae Tonkinensis heat clearing and damp drying, eliminating fire and detoxication, relieving sore throat and diminishing swelling; Bulbus Fritillariae taipaiensis, the cough-relieving of nandina moistening the lung and resolving phlegm, arresting convulsion clears away heart-fire; Radix Platycodonis, Pericarpium Citri tangerinae lung qi dispersing eliminate the phlegm, sore-throat relieving evacuation of pus, regulating qi-flowing for strengthening spleen; The Cortex Magnoliae Officinalis promoting the circulation of QI to remove dampness, removing food stagnancy is relievingd asthma.

Clinical data

1, the selected case of the physical data 130 routine acute upper respiratory tract infection infants of all being in hospital in my institute's department of pediatrics year November from May, 2009～2009.130 examples are 0.5～8 years old infant, and clinical cardinal symptom all has heating, with in various degree laryngopharynx swelling and pain, cough, nasal obstruction watery nasal discharge etc., 6 examples of wherein fainting from fear.Carry out routine blood test and chest audible inspection for routinely 130 routine infants, normal or on the low side 95 examples of leukocyte in the blood, the leukocyte person of increasing 33 examples, chest sign feminine gender meets the diagnostic criteria of children acute upper respiratory tract infection.Be divided into treatment at random and organize 65 examples, male 32 examples wherein, women 33 examples; Matched group 65 examples, male 34 examples wherein, women 31 examples.Comparing difference does not have significance before two groups of data treatments, has comparability.

Coloclysis when 2 Therapeutic Method are treated medicine temperature drop to 37 ℃ allows behind children's's defecation, gets left lateral position, with transfusion sebific duct (aseptic scalp acupuncture is cut off the syringe needle part) by the coloclysis requirement with aseptic scalp acupuncture insertion anus, go into intestinal with the speed of 30～40 of per minutes.With enema about 80～100 milliliters, defecation not in 1～2 hour as far as possible.Every day 1 time, 7 is the course for the treatment of.Matched group, with virazole and the penicillin treatment of convention amount agent, duplicate injection in case of necessity or give Physical temperature-lowering.7 was 1 course for the treatment of.

3 criterion of therapeutical effect produce effects: body temperature is down to normally, and symptoms such as cough, pharyngeal hyperemia, watery nasal discharge are significantly improved; Effectively: body temperature descends, but the axil temperature is still at 37.2 ℃～37.5 ℃ or still have symptoms such as slight cough, pharynx be red; Invalid: symptom, sign do not have and improve or axil temperature more than 38.5 ℃.

4, therapeutic outcome

In 2 week for the treatment of two groups of patients are carried out follow-up observation, the result shows that the totall effective rate in clinical treatment for the treatment of group and matched group is respectively 95.3% and 81.5%, two group of comparing difference statistical significance (P＜0.01), and two groups of curative effects relatively see Table 1.

Table 1 liang group infant curative effect is [n (%)] relatively

Two groups of infant treatment back body temperature begin to descend and reply normal time and relatively see Table 2

Table 2 liang group infant treatment back body temperature begins to descend and replys relatively (x ± s) of normal time

Annotate: P＜0.01

The specific embodiment

Embodiment one: get Folium wrightiae pubescentis 12g, Radix Ilicis Pubescentis 8g, Herba Ephedrae 8g, Herba Schizonepetae 9g, Herba Passiflorae Foetidae 8g, Flos Chrysanthemi 7g, Radix Bupleuri 11g, Radix Sophorae Tonkinensis 7g, Bulbus Fritillariae taipaiensis 8g, nandina 6g, Radix Platycodonis 7g, Pericarpium Citri tangerinae 6g, Cortex Magnoliae Officinalis 11g, in cold water, soak earlier 15～20min, the reuse big fire is boiled, 10～the 20min that simmers in water at last, fried one-tenth 200ml medicinal liquid is standby.

Embodiment two: get Folium wrightiae pubescentis 10g, Radix Ilicis Pubescentis 9g, Herba Ephedrae 6g, Herba Schizonepetae 7g, Herba Passiflorae Foetidae 10g, Flos Chrysanthemi 5g, Radix Bupleuri 10g, Radix Sophorae Tonkinensis 5g, Bulbus Fritillariae taipaiensis 7g, nandina 5g, Radix Platycodonis 5g, Pericarpium Citri tangerinae 6g, Cortex Magnoliae Officinalis 10g, preparation method is with embodiment one.

Embodiment three: get Folium wrightiae pubescentis 13g, Radix Ilicis Pubescentis 6g, Herba Ephedrae 9g, Herba Schizonepetae 10g, Herba Passiflorae Foetidae 7g, Flos Chrysanthemi 8g, Radix Bupleuri 12g, Radix Sophorae Tonkinensis 8g, Bulbus Fritillariae taipaiensis 10g, nandina 7g, Radix Platycodonis 8g, Pericarpium Citri tangerinae 8g, Cortex Magnoliae Officinalis 12g, preparation method is with embodiment one.

Claims (1)

1. herbal enema agent for the treatment of infantile acute upper respiratory infection is characterized in that this herbal enema agent made by the Chinese medicine of following weight: Folium wrightiae pubescentis 12g, Radix Ilicis Pubescentis 8g, Herba Ephedrae 8g, Herba Schizonepetae 9g, Herba Passiflorae Foetidae 8g, Flos Chrysanthemi 7g, Radix Bupleuri 11g, Radix Sophorae Tonkinensis 7g, Bulbus Fritillariae taipaiensis 8g, nandina 6g, Radix Platycodonis 7g, Pericarpium Citri tangerinae 6g, Cortex Magnoliae Officinalis 11g.