CN101485724A - Medicament for relieving exterior syndrome - Google Patents

Medicament for relieving exterior syndrome Download PDF

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Publication number
CN101485724A
CN101485724A CN 200810056304 CN200810056304A CN101485724A CN 101485724 A CN101485724 A CN 101485724A CN 200810056304 CN200810056304 CN 200810056304 CN 200810056304 A CN200810056304 A CN 200810056304A CN 101485724 A CN101485724 A CN 101485724A
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China
Prior art keywords
parts
radix
herba
medicine
aqueous solution
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Pending
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CN 200810056304
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Chinese (zh)
Inventor
王丽娟
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BEIJING TIANKE RENXIANG MEDICAL SCI-TECH Co Ltd
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BEIJING TIANKE RENXIANG MEDICAL SCI-TECH Co Ltd
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Priority to CN 200810056304 priority Critical patent/CN101485724A/en
Publication of CN101485724A publication Critical patent/CN101485724A/en
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Abstract

The invention discloses a medicine for relieving exterior syndromes, which uses herba ephedrae, schizonepeta spike, perilla leaves, radix bupleuri, burdock, radix puerariae, angelica dahurica, radix sileris and mother chrysanthemum as raw materials to prepare granular formulation or capsule through extracting and processing. The drugs are matched and interact with each other, so the medicine has the advantages of rapid effect, high curative effect and small toxic and side effects. The medicine has the efficacies of dispelling wind and relieving exterior syndrome, and clearing away heat and toxic material, and is mainly used for rheum caused by exterior chill with damp, and patients with exterior syndromes, such as headache, fever, chill, anidrosis, sore of limbs and the like.

Description

A kind of diaphoretic medicine
Technical field
The invention belongs to the Chinese medicine preparation technical field, be specifically related to a kind of diaphoretic medicine.Be to be used for affection of exogenous wind-cold to hold flu due to wet under the arm specifically, as a kind of diaphoretic medicine of table disease persons such as headache, heating, aversion to cold, lossless, limb aching pain.
Technical background
Motherland's medical science thinks that this class medicine generally all has diaphoresis or diaphoretic effect, by diaphoresis pathogenic factor in the exterior is separated from antiperspirant, what is called " it is at skin person inducing diaphoresis " is arranged, " high fever like the burning coal over the body; sweating and loose " theory, visible diaphoresis is one of important method of treatment of Chinese traditional treatment exterior syndrome.
So-called exterior syndrome just is meant that disease is at shallow table.Be more common in the diseases caused by exogenous pathogenic factor initial stage, pulmonary is subjected to heresy, and symptom has aversion to cold, fever and headache, lossless or antiperspirant, nasal obstruction, cough, floating pulse etc. are arranged.The upper respiratory tract infection and the symptom at infectious disease initial stage that are equivalent to modern medicine.Exterior syndrome is to invade the flesh table by exopathogen to be caused.
This type of diaphoretic medicine provided by the invention is classical Chinese patent medicine, its effect of inducing sweat is to interact between interior each medicine in the side of utilizationing, plays pharmacological actions such as diaphoresis, analgesic, analgesia and antibiotic, antiviral, has improved drug bioavailability, curative effect is rapid, will get well than other diaphoretic medicines.
Summary of the invention
The object of the invention provides a kind of diaphoretic medicine, and the prescription and the technology of this medicine have been done correlational study, to overcome the deficiency of existing medicine, better meets the needs of health care.
Be achieved through the following technical solutions order of the present invention:
1, the present invention is the preparation of being made by the following weight proportion raw material:
30~150 parts of 30~150 parts of Folium Perillaes of 30~80 parts of Herba Schizonepetaes of Herba Ephedrae
30~80 parts of 30~150 parts of Radix Puerariaes of 30~80 parts of Fructus Arctiis of Radix Bupleuri
30~150 parts of 30~80 parts of Flos Chrysanthemis of 30~80 parts of Radix Saposhnikoviaes of the Radix Angelicae Dahuricae
2, the present invention is the preparation of being made by following preferred weight proportion raw material:
50~120 parts of 50~120 parts of Folium Perillaes of 35~70 parts of Herba Schizonepetaes of Herba Ephedrae
40~70 parts of 40~100 parts of Radix Puerariaes of 30~80 parts of Fructus Arctiis of Radix Bupleuri
50~120 parts of 40~70 parts of Flos Chrysanthemis of 30~80 parts of Radix Saposhnikoviaes of the Radix Angelicae Dahuricae
3, best each the raw material weight proportioning of prescription of the present invention is:
90 parts of 90 parts of Folium Perillaes of 65 parts of Herba Schizonepetaes of Herba Ephedrae
60 parts of 65 parts of Radix Puerariaes of 50 parts of Fructus Arctiis of Radix Bupleuri
100 parts of 50 parts of Flos Chrysanthemis of 50 parts of Radix Saposhnikoviaes of the Radix Angelicae Dahuricae
4, preparation technology
Process program 1:
(1) get Herba Schizonepetae, Folium Perillae extraction volatile oil, the aqueous solution after distillation device is in addition collected;
(2) seven flavors such as all the other Herba Ephedraes decoct with water 2~4 times, and each 1~3 hour, filter, filtrate and the merging of above-mentioned aqueous solution, being concentrated into relative density is the thick paste of 1.31~1.34 (50~80 ℃);
(3) get thick paste, add cane sugar powder, dextrin is an amount of, makes granule with 90% ethanol, drying, spray adds above-mentioned Herba Schizonepetae, Folium Perillae volatile oil, and mixing is made granule or is incapsulated, promptly.
Process program 2:
(1) get Herba Schizonepetae, Folium Perillae extraction volatile oil, the aqueous solution after distillation device is in addition collected;
(2) seven flavors such as all the other Herba Ephedraes decoct with water 2~4 times, and each 1~3 hour, filter, filtrate and the merging of above-mentioned aqueous solution, being concentrated into relative density is the clear paste of 1.10~1.13 (40~70 ℃), spray drying is made dried cream powder;
(3) getting above-mentioned dried cream powder, to add lactose an amount of, mixes, and spray adds above-mentioned Herba Schizonepetae, Folium Perillae volatile oil, and mixing is made granule or incapsulated, promptly.
The present invention is by optimization formula, the comprehensively interaction between each medicine, and behind the selection process effective component extracting, granule of making or capsule.Be used for affection of exogenous wind-cold and hold flu due to wet under the arm, disease is seen table disease persons such as headache, heating, aversion to cold, lossless, limb aching pain.With above-mentioned Chinese medicine composition and preparation technology thereof, help bringing into play the integration regulating action of medicine, play the effect of dispelling wind to relieve the exterior syndrome, heat-clearing and toxic substances removing.
Embodiment 1:
Adopt following prescription:
90 parts of 90 parts of Folium Perillaes of 65 parts of Herba Schizonepetaes of Herba Ephedrae
60 parts of 65 parts of Radix Puerariaes of 50 parts of Fructus Arctiis of Radix Bupleuri
100 parts of 50 parts of Flos Chrysanthemis of 50 parts of Radix Saposhnikoviaes of the Radix Angelicae Dahuricae
Its preparation technology is:
(1) get Herba Schizonepetae, Folium Perillae extraction volatile oil, the aqueous solution after distillation device is in addition collected;
(2) seven flavors such as all the other Herba Ephedraes decoct with water 2 times, and each 1.5 hours, filter, filtrate and the merging of above-mentioned aqueous solution, being concentrated into relative density is the thick paste of 1.31~1.34 (70 ℃);
(3) get thick paste, add cane sugar powder 10g, dextrin 10g, make granule with 90% ethanol, drying, spray adds above-mentioned Herba Schizonepetae, Folium Perillae volatile oil, and mixing is made granule, promptly.
Embodiment 2:
Adopt the prescription of embodiment 1:
90 parts of 90 parts of Folium Perillaes of 65 parts of Herba Schizonepetaes of Herba Ephedrae
60 parts of 65 parts of Radix Puerariaes of 50 parts of Fructus Arctiis of Radix Bupleuri
100 parts of 50 parts of Flos Chrysanthemis of 50 parts of Radix Saposhnikoviaes of the Radix Angelicae Dahuricae
Its preparation technology is:
(1) get Herba Schizonepetae, Folium Perillae extraction volatile oil, the aqueous solution after distillation device is in addition collected;
(2) seven flavors such as all the other Herba Ephedraes decoct with water 3 times, and each 1 hour, filter, filtrate and the merging of above-mentioned aqueous solution, being concentrated into relative density is the clear paste of 1.10~1.13 (65 ℃), spray drying is made dried cream powder;
(3) get above-mentioned dried cream powder and add lactose 20g, mix, spray adds above-mentioned Herba Schizonepetae, Folium Perillae volatile oil, and mixing incapsulates, promptly.
Experimental example:
Write out a prescription by the present invention of many animal pharmacological tests proof and to have following pharmacological action between the Chinese medicine:
1. perspiration: this class medicine generally all has diaphoresis or diaphoretic effect, by diaphoresis pathogenic factor in the exterior is separated from antiperspirant.Contained volatile oil has perspiration in this side's epheday intermedia, and test confirms that ephedrine and Herba Ephedrae water solubility extract can impel the laboratory animal diaphoresis.
2. refrigeration function: this class medicine has refrigeration function in various degree mostly, and experimental pyrogenicity animal heat is reduced, and is the most remarkable with the Radix Bupleuri effect.Other be by diaphoresis or promote diaphoresis to finish as Herba Schizonepetae, Radix Saposhnikoviae, Radix Puerariae, its model of action of Folium Perillae.In addition, Radix Puerariae etc. reduces the effect of normal body temperature in addition.
3. analgesic activity: Radix Bupleuri, Radix Saposhnikoviae, Folium Perillae etc. all have the obvious suppression effect to the pain reaction that mouse tail acetic acid twisting method etc. causes, show that they all have certain analgesic activity.
4. antibiotic, antivirus action: experiment in vitro proves, Radix Bupleuri, Folium Perillae, Radix Saposhnikoviae etc. are to various bacteria, as golden Portugal bacterium, Streptococcus hemolyticus, Bacillus typhi, dysentery bacterium, tuberculosis bar mattress and some pathogenic fungus certain inhibitory action is arranged respectively, Herba Ephedrae, Radix Bupleuri, Folium Perillae, Flos Chrysanthemi etc. have certain inhibitory action to influenza virus.

Claims (4)

1, a kind of diaphoretic medicine is characterized in that it is made by following materials of weight proportions:
30~150 parts of 30~150 parts of Folium Perillaes of 30~80 parts of Herba Schizonepetaes of Herba Ephedrae
30~80 parts of 30~150 parts of Radix Puerariaes of 30~80 parts of Fructus Arctiis of Radix Bupleuri
30~150 parts of 30~80 parts of Flos Chrysanthemis of 30~80 parts of Radix Saposhnikoviaes of the Radix Angelicae Dahuricae.
2, a kind of diaphoretic medicine as claimed in claim 1 is characterized in that the preferred weight proportioning of each component is:
50~120 parts of 50~120 parts of Folium Perillaes of 35~70 parts of Herba Schizonepetaes of Herba Ephedrae
40~70 parts of 40~100 parts of Radix Puerariaes of 30~80 parts of Fructus Arctiis of Radix Bupleuri
50~120 parts of 40~70 parts of Flos Chrysanthemis of 30~80 parts of Radix Saposhnikoviaes of the Radix Angelicae Dahuricae.
3, a kind of diaphoretic medicine as claimed in claim 1 is characterized in that the optimum weight proportioning of each component is:
90 parts of 90 parts of Folium Perillaes of 65 parts of Herba Schizonepetaes of Herba Ephedrae
60 parts of 65 parts of Radix Puerariaes of 50 parts of Fructus Arctiis of Radix Bupleuri
100 parts of 50 parts of Flos Chrysanthemis of 50 parts of Radix Saposhnikoviaes of the Radix Angelicae Dahuricae.
4, a kind of diaphoretic medicine as claimed in claim 3 is characterized in that the preparation technology of this Chinese medicine is:
Process program 1:
(1) get Herba Schizonepetae, Folium Perillae extraction volatile oil, the aqueous solution after distillation device is in addition collected;
(2) seven flavors such as all the other Herba Ephedraes decoct with water 2~4 times, and each 1~3 hour, filter, filtrate and the merging of above-mentioned aqueous solution, being concentrated into relative density is the thick paste of 1.31~1.34 (50~80 ℃);
(3) get thick paste, add cane sugar powder, dextrin is an amount of, makes granule with 90% ethanol, drying, spray adds above-mentioned Herba Schizonepetae, Folium Perillae volatile oil, and mixing is made granule or is incapsulated, promptly.
Process program 2:
(1) get Herba Schizonepetae, Folium Perillae extraction volatile oil, the aqueous solution after distillation device is in addition collected;
(2) seven flavors such as all the other Herba Ephedraes decoct with water 2~4 times, and each 1~3 hour, filter, filtrate and the merging of above-mentioned aqueous solution, being concentrated into relative density is the clear paste of 1.10~1.13 (40~70 ℃), spray drying is made dried cream powder;
(3) getting above-mentioned dried cream powder, to add lactose an amount of, mixes, and spray adds above-mentioned Herba Schizonepetae, Folium Perillae volatile oil, and mixing is made granule or incapsulated, promptly.
CN 200810056304 2008-01-16 2008-01-16 Medicament for relieving exterior syndrome Pending CN101485724A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200810056304 CN101485724A (en) 2008-01-16 2008-01-16 Medicament for relieving exterior syndrome

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Application Number Priority Date Filing Date Title
CN 200810056304 CN101485724A (en) 2008-01-16 2008-01-16 Medicament for relieving exterior syndrome

Publications (1)

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CN101485724A true CN101485724A (en) 2009-07-22

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101653507A (en) * 2009-08-10 2010-02-24 黄山 Particle for relieving heat and cough
CN102648958A (en) * 2012-04-20 2012-08-29 宋庆银 Traditional Chinese medicine enema for treating acute upper respiratory infections of children
CN103054020A (en) * 2012-12-28 2013-04-24 祝凤仪 Kudzuvine root powder having effects of inducing sweat and dispelling exogenous evils and preparation method thereof
CN104173988A (en) * 2014-09-04 2014-12-03 薛学明 Medicine for treating cold and preparation method thereof
CN105362341A (en) * 2015-12-12 2016-03-02 贵州省施秉县万富农业科技发展有限公司 Traditional Chinese medicine prescription for treating cold type cold and cough
CN105998187A (en) * 2016-05-12 2016-10-12 安徽安庆市金徽酒业有限公司 Exterior syndrome relieving medicinal liquor
CN107596271A (en) * 2017-09-30 2018-01-19 四川德药药业有限公司 A kind of clear pest anti virus herb composition

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101653507A (en) * 2009-08-10 2010-02-24 黄山 Particle for relieving heat and cough
CN102648958A (en) * 2012-04-20 2012-08-29 宋庆银 Traditional Chinese medicine enema for treating acute upper respiratory infections of children
CN103054020A (en) * 2012-12-28 2013-04-24 祝凤仪 Kudzuvine root powder having effects of inducing sweat and dispelling exogenous evils and preparation method thereof
CN103054020B (en) * 2012-12-28 2013-10-30 祝凤仪 Kudzuvine root powder having effects of inducing sweat and dispelling exogenous evils and preparation method thereof
CN104173988A (en) * 2014-09-04 2014-12-03 薛学明 Medicine for treating cold and preparation method thereof
CN105362341A (en) * 2015-12-12 2016-03-02 贵州省施秉县万富农业科技发展有限公司 Traditional Chinese medicine prescription for treating cold type cold and cough
CN105998187A (en) * 2016-05-12 2016-10-12 安徽安庆市金徽酒业有限公司 Exterior syndrome relieving medicinal liquor
CN107596271A (en) * 2017-09-30 2018-01-19 四川德药药业有限公司 A kind of clear pest anti virus herb composition

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Open date: 20090722