CN102631307B - Skin care composition and preparation with effect of removing acnes and acne marks and preparation method of skin care composition - Google Patents
Skin care composition and preparation with effect of removing acnes and acne marks and preparation method of skin care composition Download PDFInfo
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Abstract
The invention discloses a skin care composition with the effect of removing acnes and acne marks. The composition comprises a phase A, a phase B and a phase C. Experiments prove that the composition has the effect of inhibiting formation of melanin and has obvious effect on inhibiting skin oil excretion; people know such symptoms as acnes and pimples are mostly caused by pathogenic bacteria and the oil excreted by the skin is exactly the best environment for the pathogenic bacteria to grow, so bacteriostasis is not enough and the living environment of the pathogenic bacteria needs to be fundamentally eliminated so as to have the effect of treating acnes and pimples; the composition has the effect of removing acnes by inhibiting oil excretion; the composition has obvious effect on treating acne marks, after the composition is used for three weeks, the acne marks of the patients are obviously improved; and the composition also has obvious effect on removing other scar tissues caused by wounds.
Description
Technical field
The present invention relates to a kind of skin care compositions, specifically a kind of skin care compositions with pox-dispelling function effect, preparation and preparation method thereof.
Background technology
Along with social progress, the improving constantly of living standards of the people, cosmetics become the necessary of people's life gradually from luxury goods, the kind of cosmetics is more and more, in recent years, the mask product of showing one's talent in many cosmetics of comforming, the more and more favor of Shen Shou consumer.
Facial film is that index is on human body skin surface, play the product clean and effect of protection skin, its works principle is the parcel to skin by facial film, allow skin and air insulated, make skin and air insulated, make keratodermatitis obtain supplementing of moisture, wetting agent, nutrient and softening agent etc. contained in facial film, play the effect of soft skin; Facial film also has adsorption, while peelling off facial film, can remove dirt, oils and fats and acne on skin simultaneously, careful pore, and the skin that compacts, plays good clean skin and skin care effect.
Modern medicine is thought: the result that acne is multifactor functioning.First, endocrine in body: be mainly that androgen secretion level increases, impels sebum secretion to enliven, increase.It is the key factor in pathogenesis that leather bag sebaceous gland opening gets clogged.In the situation that hair follicle blocks, propionibacterium acnes amount reproduction, causes inflammation, forms the most basic infringement inflammatory pimple of acne (comedo).In inaccessible pilosebaceous unit inside, a large amount of sebums, a large amount of pus cell pilosebaceous unit structural deterioration, form tuberosity, cyst and sebaceous cyst, finally destroys skin and even form cicatrix.
At present commercially available skin-protection product has and much has acne-removing, but thereby in its just simple antibacterial short time, play effect of anti-acne, but life-time service, relapse rate is higher, and to scar tissues such as pockmark pox seals without obvious effect.
Summary of the invention
The invention discloses a kind of skin care compositions that skin care presses down fat and pox-dispelling function effect that has.
A further object of the present invention is to propose a kind of skin protection dosage form of above-mentioned composition.
The 3rd object of the present invention is to propose a kind of preparation method of above-mentioned skin protection dosage form.
The present invention utilizes advanced biotechnology, in conjunction with the traditional traditional Chinese medical science compatibility theory of China, in line with the principle of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, dredging the meridian, successfully develops the volcanic mud facial film with anti-acne seal effect.
A volcanic mud facial film with acne-removing, the active component of this cosmetic composition contains natural minerals mud, has effect of deep layer cleaning skin; Other compositions of the composite the present invention of volcanic mud have good facilitation to the metabolism of skin, they can not only keep moisture of skin here, can also suppress chafing, removing dead skin cells and oils and fats piles up, stimulate blood circulation, softening skin, deep clean skin and purification pore, the most important thing is that pox to staying after anti-acne prints cicatrix and has and well dispel effect, the scar tissue due to other wounds of skin is also had to the effect of smoothing.
The concrete technical scheme that the present invention adopts is:
Have the skin care compositions of pox-dispelling function effect, described compositions comprises A phase, B phase and C phase, and described A phase, B phase and C comprise following percentage by weight raw material mutually:
Described compositions also comprises D phase, and described D comprises following materials by weight percentage mutually:
Antiseptic 0.05～0.2wt%
Essence 0.01～0.2wt%.
Prepare a method for described skin care compositions, described step is as follows:
(1) Magnesiumaluminumsilicate and water are mixed to get mixture solution, are heated to 60～90 ℃, homogenizing 10～40min;
(2) by B mutually in HANSHENGJIAO be added in butanediol and mix in advance, then mutually other do not obtain mixed solution B with joining together with raw material in the mixture solution of step (1) with B;
(3) mutually all A raw materials are mixed to get to mixed solution A;
(4) mixed solution A, mixed solution B are heated to respectively to 60～90 ℃, on homogenizer, mixed solution A enters in mixed solution B, 2～5 points of kinds of homogenizing;
(5) cool and be stirred to 30～50 ℃, add C phase raw material, stir.
In described step (1), be heated to 80 ℃, homogenizing 20min.
Described step, as above-mentioned, also comprises that step (6) adds D phase raw material, stirs.
Have the skin care formulation of pox-dispelling function effect, described skin care formulation is made up through said method of described compositions.
Described skin care formulation is facial film.
Described skin care compositions has the purposes in the skin care formulation of pox-dispelling function effect in preparation.
The recommendation method of facial film of the present invention:
After facial cleansing, directly smear product of the present invention, 5～10g/ time, be as the criterion to cover skin comprehensively, after reservation 15min, clean and smear once for 2 days, one week 3 times.
Beneficial effect of the present invention:
Confirm through experiment, the present invention has effect that check melanin forms; To skin oil and fat, secretion has significant inhibition, we know that the symptoms such as acne seat skin ulcer mostly are pathogen and cause, and the oils and fats of the skin secretion suitable environment of pathogen growth just, only antibacterial is inadequate, thereby need in root, eliminate pathogen living environment and play the effect of curing acne and seat skin ulcer, the present invention plays acne-removing by the secretion of oil-control.The present invention is printed on obvious therapeutic efficiency to pox, uses after three weeks, and patient's pox prints and improves significantly, and the scar tissue simultaneously other wounds being caused also has significantly dispels effect.
Accompanying drawing explanation
Fig. 1 is melanin situation of change after sample uses;
Fig. 2 is haemachrome situation of change after sample uses;
Fig. 3 is fat content situation of change after sample uses;
Fig. 4 is skin coarseness situation of change after sample uses;
Fig. 5 is skin mean depth situation of change after sample uses;
Fig. 6 is for using 4 weeks poxes of this product to print number change figure.
The specific embodiment
The each raw material sources of the present invention, in table 1:
Table 1
Volcanic mud be ash to black without stickiness mud, contain mineral, be generally all distributed in submarine volcano and volcanic island shallow sea and abyssal floor around.Volcanic mud is known raw material at cosmetic field, and those skilled in the art can obtain by commercially available purchase.The present invention to the specifications and models of volcanic mud without specific (special) requirements, as long as the volcanic mud additive of cosmetics-stage all can be used for the present invention, the invention discloses two producers of selling volcanic mud, and verify and all can obtain result of the present invention through embodiment, in table 1, the commercially available volcanic mud product of other producers all can be applicable to the present invention, and other contain enrich mineral and meet cosmetics grade also can substitute volcanic mud as raw material for the present invention.
Opuntia Streptacantha stem extract is the conventional raw material of skin care field, can obtain by commercially available purchase, also can prepare by subordinate's method, and concrete steps are:
1) with cellulose treatment Opuntia Streptacantha stem, with degradation of cell wall, obtain cell pyrolysis liquid;
2), by cell pyrolysis liquid enzyme denaturing, the solution left standstill after enzyme denaturing, gets supernatant;
3) regulate the pH value to 4.2 of supernatant, then add wherein activated carbon, stir, filter, collect filtrate, obtain Opuntia Streptacantha extract;
Tremella extract is the conventional raw material of skin care field, can obtain by commercially available purchase, also can prepare by subordinate's method, and concrete steps are:
1) soak Tremella with deionized water, the weight ratio of water and Tremella is 100: 1.
2) regulate between pH value to 8.5～9.0, in 85～95 ℃ of isothermal reactions 3～5 hours.
3) stir, filter, sucking filtration, collects filtrate, obtains Tremella extract.
Radix Ophiopogonis extract is the conventional raw material of skin care field, can obtain by commercially available purchase, also can prepare by subordinate's method, and concrete steps are:
1) will shred Radix Ophiopogonis with pulper, soak Radix Ophiopogonis with deionized water, the weight ratio of water and Radix Ophiopogonis is 20: 1.
2) regulate between pH value to 8.5～9.0, in 45～55 ℃ of isothermal reactions 1 hour.
3) stir, filter, sucking filtration, collects filtrate, obtains Radix Ophiopogonis extract.
The preparation of embodiment 1 facial film of the present invention
Raw material and consumption:
Preparation method:
(1) Magnesiumaluminumsilicate and water are mixed to get mixture solution, are heated to 70 ℃, homogenizing 15min;
(2) by B mutually in HANSHENGJIAO be added in butanediol and mix in advance, then mutually other do not obtain mixed solution B with joining together with raw material in the mixture solution of step (1) with B;
(3) by A mutually all raw materials be mixed to get mixed solution A;
(4) mixed solution A, mixed solution B are heated to respectively to 70 ℃, on homogenizer, mixed solution A is slowly poured in mixed solution B, 5 points of kinds of homogenizing;
(5) cool and be stirred to 45 ℃, stir speed (S.S.) is: 30r/min, 0.5 ℃/min of rate of temperature fall; Add C phase raw material, stir.
(6) add D phase raw material, stir, suggestion stir speed (S.S.) is: 30r/min, rear subpackage.
Detect data:
Evenly mastic or emulsion; Fragrance conforms with the regulations; PH value (25 ℃)=7.16, has cold-resistant temperature capacity, and preservation challenge is passed through; According to " diagnostic criteria of cosmetics contact dermatitis and treatment principle " criterion, embodiment 1 prepares facial film human body skin is had no adverse reaction.
The preparation of embodiment 2 mask product of the present invention
Raw material and consumption:
Preparation method:
(1) Magnesiumaluminumsilicate and water are mixed to get to mixture solution, are heated to 60 ℃, homogenizing 10min;
(2) by B mutually in HANSHENGJIAO be added in butanediol and mix in advance, then mutually other do not obtain mixed solution B with joining together with raw material in the mixture solution of step (1) with B;
(3) by A mutually all raw materials be mixed to get mixed solution A;
(4) mixed solution A, mixed solution B are heated to respectively to 80 ℃, on homogenizer, mixed solution A enters in mixed solution B, 5 points of kinds of homogenizing;
(5) cool and be stirred to 30 ℃, stir speed (S.S.) is: 30r/min, 0.5 ℃/min of rate of temperature fall; Add C phase raw material, stir;
(6) add D phase raw material, stir, suggestion stir speed (S.S.) is: 30r/min, rear subpackage.
Detect data:
Evenly mastic or emulsion; Fragrance conforms with the regulations; PH value (25 ℃)=7.15 has cold-resistant temperature capacity preservation challenge to be passed through; According to " diagnostic criteria of cosmetics contact dermatitis and treatment principle " criterion, volcanic mud facial film has no adverse reaction to human body skin.
The preparation of embodiment 3 mask product of the present invention
Raw material and consumption:
Preparation method:
(1) Magnesiumaluminumsilicate and water are mixed to get mixture solution, are heated to 90 ℃, homogenizing 40min;
(2) by B mutually in HANSHENGJIAO be added in butanediol and mix in advance, obtain mixed solution B in then joining mutually the mixture solution of step (1) together with other raw materials with B;
(3) by A mutually all raw materials be mixed to get mixed solution A;
(4) mixed solution A, mixed solution B are heated to respectively to 90 ℃, on homogenizer, mixed solution A enters in mixed solution B, 2 points of kinds of homogenizing;
(5) cool and be stirred to 50 ℃, stir speed (S.S.) is: 30r/min, 0.5 ℃/min of rate of temperature fall; Add C phase raw material, stir;
(6) add D phase raw material, stir, subpackage.
Detect data:
Evenly mastic or emulsion; Fragrance conforms with the regulations; PH value (25 ℃)=7.18 has cold-resistant temperature capacity, and preservation challenge is passed through; According to " diagnostic criteria of cosmetics contact dermatitis and treatment principle " criterion, volcanic mud facial film has no adverse reaction to human body skin.
The preparation of embodiment 4 facial films of the present invention
Raw material and consumption:
Preparation method:
(1) Magnesiumaluminumsilicate and water are mixed to get mixture solution, are heated to 70 ℃, homogenizing 15min;
(2) by B mutually in HANSHENGJIAO be added in butanediol and mix in advance, then mutually other do not obtain mixed solution B with joining together with raw material in the mixture solution of step (1) with B;
(3) by A mutually all raw materials be mixed to get mixed solution A;
(4) mixed solution A, mixed solution B are heated to respectively to 70 ℃, on homogenizer, mixed solution A is slowly poured in mixed solution B, 5 points of kinds of homogenizing;
(5) cool and be stirred to 45 ℃, stir speed (S.S.) is: 30r/min, 0.5 ℃/min of rate of temperature fall; Add C phase raw material, stir.
Detect data:
Evenly mastic or emulsion; Fragrance conforms with the regulations; PH value (25 ℃)=7.16, has cold-resistant temperature capacity, and preservation challenge is passed through; According to " diagnostic criteria of cosmetics contact dermatitis and treatment principle " criterion, embodiment 1 prepares facial film human body skin is had no adverse reaction.
Effect experiment of the present invention
One, experimental principle
Human experimentation, by particular experiment, crowd forms test population, and test subject makes the variation of the dark red pigment of front and back skin, oils and fats and skin texture degree that applies some make up, thereby determines that the anti-acne of cosmetics prints effect.And print the organoleptic indicator of effect by anti-acne, thereby determine that the anti-acne of cosmetics prints effect.
Two, experimental apparatus and sample
Instrument: dermal melanin and haemachrome tester (Mexameter MX18, German CK electronics corporation produces); Skin oil and fat tester
sM815 (Mexameter MX18, German CK electronics corporation produces): MicroSkinII Multi-functional skin mirror image analysis system.
Three, experiment crowd and the testing time
Volunteer totally 30 people that participate in this detection, sex composition is random, and the age was at 20～30 years old.If there is during this time 1 people to occur untoward reaction, stop test; Result is not found untoward reaction.
Volunteer service time: smear once for 2 days.
Four, experimental technique
Experimenter smears before sample, first will try experiment position and clean, and after drying, smears sample.Experimenter's forehead (point left and right two parts) cycle labeling successively: tested region samples group and blank region.
After making continuously to apply some make up, the same time is carried out data acquisition to experimenter weekly.
Add up each gathered data, and carry out integral analysis of data.
Five, interpretation of result
1, melanin
(1) melanin content mutation analysis
Melanin content was reflected in test period, Experimental Area melanin content change with time.
As shown in Figure 1: sample is using 1～4 week, and melanin content is on a declining curve.
2, haemachrome
(1) content of hemachrome mutation analysis
Content of hemachrome was reflected in test period, Experimental Area content of hemachrome change with time.
As shown in Figure 2: sample is after using two weeks, and haemachrome is obviously reduction trend.
3, oils and fats
(1) fat content
Fat content variation was reflected in test period, Experimental Area fat content change with time.Its value is larger, and fat content is larger, otherwise fat content is less.
As shown in Figure 3: sample is after using 1～4 week, and the fat content of test zone is reduction trend.
4, skin texture situation of change:
Skin coarseness (Skin Roughness SR)
In all sections of skin, with the difference between maximum gray scale peak value and minimal gray peak value on straight line.This parameter is the maximum height of skin surface unevenness.
Skin coarseness changes of contents was reflected in test period, Experimental Area skin coarseness change with time.Its value is larger, and skin coarseness is larger, otherwise skin coarseness is less.
As shown in Figure 4: sample is after using 1～4 week, and the skin coarseness of test zone is reduction trend.
Mean depth (Skin Smoothness Depth SSD)
Average distance between two peak values of feeling the pulse with the finger-tip mark skin mound peak (maximum gradation value curve) and sulci of skin minimum point (minimal gray curve).It is the average distance between skin surface contour line peak and wrinkle of skin bottom line minimum point.
The variation of skin mean depth was reflected in test period, Experimental Area skin mean depth change with time.Its value is larger, and skin mean depth is larger, otherwise skin mean depth is less.
As shown in Figure 5: sample is after using 1～4 week, and the skin mean depth of test zone is reduction trend.
Conclusion: sample used in 1～4 week, the skin texture of the sample sets effect that has some improvement, what be embodied in experimenter's face is effect of skin care and wrinkle removal.
5, anti-acne prints the organoleptic indicator of effect
It is to be retained in the scar tissue on skin after the detumescence of the position such as acne, acne that pox prints.
Method: the pox of range estimation number experimenter face prints, and statistical method adopts overall statistical analysis technique, maps.
Known by Fig. 6, (in Fig. 6, vertical coordinate represents that 30 people face poxes print sum) sample used after three weeks, and its action effect printing for pox improves significantly.
For above-mentioned improvement, inventor proposes the present invention likely to be had too and dispels seal and smooth effect for the scar tissue that brings of other wounds except pox prints, so carried out following experiment.
Six, effect of scar eliminating experiment
1, experimental technique
Experimenter smears before sample, first experimenter's arm experiment position (cicatrix place) is cleaned, and after drying, smears sample.
Experimenter smears dosage in each test block be 3～10g/ time, within one day, smears once, and THICKNESS CONTROL, in 2mm left and right, requires to cover completely cicatrix place.Experimental session, experimenter can not smear any cosmetics at experiment position.
After making continuously to apply some make up, the same time is carried out data acquisition to experimenter weekly.Use 4 weeks.
Add up each gathered data, and carry out integral analysis of data.
2, experiment crowd and the testing time
Volunteer totally 30 people that participate in this detection, sex composition is random, and the age was at 20～45 years old.Requirement is the people who has cicatrix on arm, and cicatrix area control is at 4.0～50.0cm
2, the cicatrization time is no more than 10 years, and short-term does not specifically limit for a long time, old cicatrix or newly form cicatrix and can be selected in.If there is during this time 1 people to occur untoward reaction, stop test; Result is not found untoward reaction, newly forms cicatrix removal effect better, and fairly simple wound is as slight scald, and falling down the cicatrix staying causing also has removal effect.
3, judgment criteria
Be effectively that cicatrix area at least reduces 20%, skin scar place color shoals; Invalid is that cicatrix area and cicatrix place skin color are without any variation; Healing is that cicatrix disappears.
4, experimental result
In 30 examples, effective percentage is 93.33%, when invalid 6.67%, and cure rate 63.33%.
Conclusion: this product has positive effect to scar eliminating.
Seven, conclusion
Comprehensively above test result draws, its volunteer is being to use after sample:
Basic detection index from skin: oils and fats, dark red pigment and skin texture degree judge, the skin condition of its sample sets target area is improved effect.
Vision index directly perceived from skin: pox prints judgement, the state that can significantly improve target skin of its sample sets, the prolongation of time using with volunteer, it improves effect and is gradually and increases progressively trend.
Inventor utilizes again the product of embodiment 2～4 to test, and result is identical with embodiment 1, is not repeated herein.
Claims (9)
1. a skin care compositions with pox-dispelling function effect, is characterized in that, described compositions is by A phase, B phase and C phase composition, and described A phase, B phase and C are made up of following percentage by weight raw material:
2. have the skin care compositions that anti-acne prints effect, it is characterized in that, described compositions is by A phase, B phase, C phase and D phase composition, and described A phase, B phase, C phase and D are made up of following percentage by weight raw material:
3. a method of preparing skin care compositions described in claim 1, is characterized in that, its step is as follows:
(1) Magnesiumaluminumsilicate and water are mixed to get mixture solution, are heated to 60～90 ℃, homogenizing 10～40min;
(2) by B mutually in HANSHENGJIAO be added in butanediol and mix in advance, then mutually other do not obtain mixed solution B with joining together with raw material in the mixture solution of step (1) with B;
(3) mutually all A raw materials are mixed to get to mixed solution A;
(4) mixed solution A, mixed solution B are heated to respectively to 60～90 ℃, on homogenizer, mixed solution A enters in mixed solution B, homogenizing 2～5 minutes;
(5) cool and be stirred to 30～50 ℃, add C phase raw material, stir.
4. preparation method as claimed in claim 3, is characterized in that, is heated to 80 ℃, homogenizing 20min in described step (1).
5. a method of preparing skin care compositions described in claim 2, is characterized in that, its step as claimed in claim 4, also comprises that step (6) adds D phase raw material, stirs.
6. a skin care formulation with pox-dispelling function effect, is characterized in that, described skin care formulation is made up through method described in claim 4 of compositions described in claim 1.
7. a skin care formulation with pox-dispelling function effect, is characterized in that, described skin care formulation is made up through method described in claim 5 of compositions described in claim 2.
8. the skin care formulation as described in claim 6 or 7, is characterized in that, described skin care formulation is facial film.
9. the skin care compositions described in claim 1 or 2 has the purposes in the skin care formulation of pox-dispelling function effect in preparation.
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| CN201210098094.1A CN102631307B (en) | 2012-04-05 | 2012-04-05 | Skin care composition and preparation with effect of removing acnes and acne marks and preparation method of skin care composition |
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| CN201210098094.1A CN102631307B (en) | 2012-04-05 | 2012-04-05 | Skin care composition and preparation with effect of removing acnes and acne marks and preparation method of skin care composition |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1263761A (en) * | 1999-02-03 | 2000-08-23 | 黑龙江东实天然美容品有限公司 | Volcano and spring mineral mask |
| CN102000006A (en) * | 2010-12-03 | 2011-04-06 | 北京工商大学 | Skin care composite and preparation with function of eliminating facial redness and preparation methods thereof |
-
2012
- 2012-04-05 CN CN201210098094.1A patent/CN102631307B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1263761A (en) * | 1999-02-03 | 2000-08-23 | 黑龙江东实天然美容品有限公司 | Volcano and spring mineral mask |
| CN102000006A (en) * | 2010-12-03 | 2011-04-06 | 北京工商大学 | Skin care composite and preparation with function of eliminating facial redness and preparation methods thereof |
Non-Patent Citations (4)
| Title |
|---|
| AVON护肤全体验;阿芳;《产品&商机》;20060228;第86-89页 * |
| MG美即火山泥面膜;佚名;《http://cosme.pclady.com.cn/product/93356.html》;20120217;第1-3页 * |
| 佚名.MG美即火山泥面膜.《http://cosme.pclady.com.cn/product/93356.html》.2012,第1-3页. |
| 阿芳.AVON护肤全体验.《产品&商机》.2006,第86-89页. |
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