CN102613978A - Detection test piece - Google Patents
Detection test piece Download PDFInfo
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- CN102613978A CN102613978A CN2011100356084A CN201110035608A CN102613978A CN 102613978 A CN102613978 A CN 102613978A CN 2011100356084 A CN2011100356084 A CN 2011100356084A CN 201110035608 A CN201110035608 A CN 201110035608A CN 102613978 A CN102613978 A CN 102613978A
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- perforation
- test piece
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- protuberance
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- 238000012360 testing method Methods 0.000 title claims abstract description 115
- 238000001514 detection method Methods 0.000 title claims abstract description 102
- 238000005070 sampling Methods 0.000 claims abstract description 225
- 238000006243 chemical reaction Methods 0.000 claims abstract description 34
- 239000000758 substrate Substances 0.000 claims description 105
- 230000000694 effects Effects 0.000 abstract description 6
- 206010011409 Cross infection Diseases 0.000 abstract 1
- 206010029803 Nosocomial infection Diseases 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 39
- 210000004369 blood Anatomy 0.000 description 39
- 238000013098 chemical test method Methods 0.000 description 21
- 238000003487 electrochemical reaction Methods 0.000 description 7
- 239000010410 layer Substances 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000011229 interlayer Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000000835 electrochemical detection Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 230000012447 hatching Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
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- 238000012423 maintenance Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
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Abstract
The invention relates to a detection test piece. The detection test piece comprises a detection area, at least one sampling passage, at least one reaction area, at least one internal sampling area, a circuit system and at least one propping protruding piece, wherein the detection area is provided with a sampling perforation; at least one sampling passage is opposite to the sampling perforation; at least one reaction area is positioned in the sampling passage; at least one internal sampling area is positioned around the sampling perforation, and the end edge of the internal sampling area is provided with an internal sampling gap which is communicated with the sampling perforation and the sampling passage; the circuit system is electrically connected with the reaction area to achieve an effect of facilitating detected body acquisition; and at least one propping protruding piece is arranged around the sampling perforation to provide an extrusion effect of a detected part, and can solve the problem of cross infection in sampling detection.
Description
Technical field
The present invention relates to a kind of detection test piece, refer to a kind of detection test piece of gathering guidance function that has especially, with apply to one have sampling and measuring ability concurrently checkout gear.
Background technology
Development along with Measurement for Biotechnique; Script needs to particular place (like hospital, control laboratory or laboratory); And the inspection item that could detect with precision instrument and the medical professionalism talent (like doctor, docimaster or researcher), nowadays patient can be in does not need professional's house to detect.
For instance, many diabeticss all need be kept watch on the blood sugar content of its blood every day.There has been at present several systems can supply the convenient blood sugar content of keeping watch on its blood of the common people.This kind system generally include one let the user sample of blood, drawn the detection test piece; And one in order to read the meter of this detection test piece with the blood sugar content that determines this blood.
Now generally use electrochemical techniques in the blood sugar content of measuring blood, this technology provides a reaction zone that contains specific ferment reagent (for example glucose oxidase ferment and medium) usually in this detection test piece.When user is drawn blood sample in this reaction zone; This meter then can apply a voltage and detect test piece to this; This specific ferment reagent just can produce electrochemical reaction with the blood glucose in the blood sample, and this meter is measured the electric current that is generated, and calculates blood sugar content according to this electric current.
And sample of blood, drawn utilizes different devices to carry out respectively with the detection blood sample, and sample of blood, drawn is that a detection test piece collocation one is gathered with the blood-taking device of blood taking needle; Detecting blood sample then detects through above-mentioned meter.User must use blood-taking device to puncture tested position earlier; And push tested position; Again blood is drawn this reaction zone that detects test piece to this, should detect this meter of test piece insertion then and detect, because blood-taking device can be reused usually; The contact position of this blood-taking device and user just is easy to take place the problem of blood infection thus, and then causes the aleopation between user.
The existing at present checkout gear that combines this blood-taking device and this meter, but the structure of these checkout gears is too complicated, is difficult to operation; And maintenance difficult, for instance, United States Patent (USP) provides a kind of checkout gear that combines this blood-taking device and this meter No. 6506168; Can know by its Fig. 4; The detection test piece that this patent disclosed need be moved when sampling, to guarantee to obtain blood, therefore needs extra propulsion plant; In addition,, also a vacuum environment need be provided, make that the structure of whole this checkout gear is comparatively complicated, and be easy to fault, show nonideal design in order to promote the ability of gathering blood.
In order to address the above problem, the present invention provides a kind of detection test piece, is easy to the collection of a corpse or other object for laboratory examination and chemical testing, and applies to one when having the sampling and the checkout gear of measuring ability concurrently, and this checkout gear does not need the device of too complex, and can avoid the problem of aleopation.
Summary of the invention
The object of the invention is to provide a kind of detection test piece, and this detection test piece is to utilize electrochemical reaction to detect, and it is sample region in being provided with on every side of a sampling perforation is at least one, can gather and guide a corpse or other object for laboratory examination and chemical testing and get at least one reaction zone generation electrochemical reaction.
The object of the invention; Be to provide a kind of detection test piece; It is provided with at least one protruding part that compresses around a sampling perforation, can compress a tested position of a person to be measured, gets at least one reaction zone to quicken a corpse or other object for laboratory examination and chemical testing to ooze out from tested position and produces electrochemical reaction; Apply to one and have the sampling and the checkout gear of measuring ability concurrently, can reach the problem of avoiding detecting aleopation.
Technical scheme of the present invention: a kind of detection test piece is to comprise:
One detection zone, this detection zone is to have:
One sampling perforation;
At least one this sampling channel is to the perforation of should sampling;
At least one reaction zone is positioned at this sampling channel; And
Sample region in one, be positioned at this sampling perforation around, end limit of sample region is to be provided with sampling breach in this, being communicated with should sampling perforation and this sampling channel; And
One Circuits System, it electrically connects this reaction zone.
Among the present invention, more comprise:
One substrate, this substrate have substrate perforation;
One wall is covered in this substrate, and this wall has a channel spacing, and this channel spacing is to boring a hole by substrate; And
One upper cover plate is covered in this wall, and this upper cover plate has loam cake perforation;
Wherein the repeating hole position of this substrate perforation, this channel spacing and the perforation of this loam cake is to form this sampling perforation; Be to form this sampling channel between this channel spacing and this substrate, this upper cover plate.
Among the present invention; Should interior sample region be at least one interior sampling protuberance wherein; Between this sampling perforation and this sampling channel; Should interior sampling protuberance be from this sampling channel the end limit of the perforation of should sampling to be extended to this sampling perforation to protrude, sampling protuberance be formed by protuberance in the loam cake on protuberance in the substrate on this substrate or this upper cover plate in this.
Among the present invention, wherein should in front end of sampling protuberance be that the centre distance of boring a hole with this sampling is 0.2mm～2mm.
Among the present invention, wherein this loam cake perforation is and this hole position of substrate perforation for varying in size, and the zone between this loam cake perforation and the perforation of this substrate is to form sample region in.
Among the present invention, wherein the pitch-row of this sampling perforation is 0.4mm～4mm.
Among the present invention; Wherein should interior sample region more include at least one interior sampling protuberance; Between this sampling perforation and this sampling channel; Should interior sampling protuberance be from this sampling channel the end limit of the perforation of should sampling to be extended to this sampling perforation to protrude, sampling protuberance be formed by protuberance in the loam cake on protuberance in the substrate on this substrate or this upper cover plate in this.
Among the present invention, be to be provided with at least one protruding part that compresses around this sampling perforation.
Among the present invention, more comprise at least one keeper, wherein this keeper is a perforation, a kerf or a projection.
Among the present invention, it further comprises at least one outer sample region, and this outer sample region is the outside that is positioned at this detection test piece, and this outer sample region is to be communicated in this sampling channel.
The present invention also discloses a kind of detection test piece simultaneously, is to comprise:
One detection zone, this detection zone is to have:
One sampling perforation;
At least one sampling channel is to the perforation of should sampling;
At least one reaction zone is positioned at this sampling channel; And
At least one protruding part that compresses, be located at this sampling perforation around; And
One Circuits System, it electrically connects this reaction zone.
Among the present invention, more comprise:
One substrate has substrate perforation;
One wall is covered in this substrate, and this wall has a channel spacing, and this channel spacing is to boring a hole by substrate; And
One upper cover plate is covered in this wall, and this upper cover plate has loam cake perforation;
Wherein the repeating hole position of this substrate perforation, this channel spacing and the perforation of this loam cake is to form this sampling perforation, is to form this sampling channel between this channel spacing and this substrate, this upper cover plate.
Among the present invention, wherein this compresses protruding part and is located at around the perforation of this substrate, this channel spacing or the perforation of this loam cake.
Among the present invention, wherein the pitch-row of this sampling perforation is 0.4mm～4mm.
Among the present invention, wherein this height that compresses protruding part is 0.01mm～2mm.
Among the present invention; Wherein be to be provided with at least one interior sampling protuberance between this sampling channel and this sampling perforation; Should interior sampling protuberance be from this sampling channel the end limit of the perforation of should sampling to be extended to this sampling perforation to protrude; Should interior end limit of sampling protuberance be to be provided with sampling breach in, the protuberance of sampling in this be formed by protuberance in the loam cake on the interior protuberance of the substrate on this substrate or this upper cover plate.
Among the present invention, wherein should in front end of sampling protuberance be that the centre distance of boring a hole with this sampling is 0.2mm～2mm.
Among the present invention, more comprise at least one keeper, this keeper is a perforation, a kerf or a projection.
Among the present invention, it further includes at least one outer sample region, and this outer sample region is the outside that is positioned at this detection test piece, and this outer sample region is to be communicated in this sampling channel.
The beneficial effect that the present invention has: this detection test piece is easy to the collection of a corpse or other object for laboratory examination and chemical testing and is convenient to cooperate one to have sampling and the checkout gear of measuring ability concurrently and the aleopation that can avoid detecting.
Description of drawings
Fig. 1: the axonometric chart of the detection test piece of the first embodiment of the present invention;
Fig. 2: the present invention is along the profile of Figure 1A A ' hatching line;
Fig. 3: the various aspect structural representation that the present invention samples and bores a hole;
Fig. 4: the enlarged diagram that the present invention samples and bores a hole;
Fig. 5: the exploded view of first embodiment of the invention;
Fig. 6, Fig. 6 A: each layer of test piece variant sketch map of the present invention ();
Fig. 7, Fig. 7 A: each layer of test piece variant sketch map of the present invention (two);
Fig. 8, Fig. 8 A: each layer of test piece variant sketch map of the present invention (three);
Fig. 9, Fig. 9 A: each layer of test piece variant sketch map of the present invention (four);
Figure 10, Figure 10 A: each layer of test piece variant sketch map of the present invention (five);
Figure 11, Figure 11 A: each layer of test piece variant sketch map of the present invention (six);
Figure 12: sketch map is used in test piece of the present invention;
Figure 13: user mode partial schematic sectional view of the present invention;
Figure 14: look sketch map on the user mode broken section of the present invention;
Figure 15: the axonometric chart of the detection test piece of variant of the present invention;
Figure 16: the user mode partial schematic sectional view of variant of the present invention;
Figure 17: look sketch map on the user mode broken section of variant of the present invention;
Figure 18: the user mode cross-sectional schematic of another variant of the present invention.
[figure number simple declaration]
1 detects test piece 111 circuit connecting section
2 checkout gears, 112 detecting electrodes
3 tested positions, 113 leads
The perforation of 4 corpse or other object for laboratory examination and chemical testing, 121 substrates
Protuberance in 10 detection zones, 122 substrates
11 Circuits System, 123 substrate male part
12 substrates, 124 substrate orientation parts
13 walls, 131 channel spacings
14 upper cover plates, 132 interlayer keepers
The perforation of 21 sampling modules, 141 loam cakes
Protuberance in 22 detection modules, 142 loam cakes
23 blood taking needles, 143 loam cake male part
101 sampling perforation, 144 loam cake keepers
Sampling protuberance 211A sampling opening in the 102A
103 outer sample region 211C compress breach
The 103A protuberance 211D test piece keeper of sampling outward
The 103B breach 212 bar portions that sample outward
104 reaction zones, 221 test piece slots
105 sampling channels, 222 electric connectors
106 keeper A circular perforations
The 107 grip part C center of boring a hole
108 compress protruding part
The specific embodiment
For making architectural feature of the present invention and the effect reached there are further understanding and understanding, cooperate detailed explanation, explain as follows in order to preferred embodiment and accompanying drawing:
Seeing also Fig. 1 and Fig. 2, is the axonometric chart and AA ' the directional profile figure of the detection test piece of the first embodiment of the present invention.As shown in the figure, present embodiment provides a kind of detection test piece 1, and the detection test piece 1 of present embodiment is to utilize the electrochemical sensing mode to detect.Detect test piece 1 and have a detection zone 10 and a Circuits System 11; Detection zone 10 mainly is to be used for gathering a corpse or other object for laboratory examination and chemical testing 4 (for example blood) Xingqi of going forward side by side to detect; So have sampling perforation 101, two reaction zones 104 and two sampling channels 105 in this detection zone 10; Sampling perforation 101 is a through hole, supplies a blood taking needle 23 to pass and gather a blood corpse or other object for laboratory examination and chemical testing 4 of a person to be measured.Two reaction zones 104 are positioned at sampling channel 105.Be provided with sample region 102 in around this sampling perforation 101; Should in sample region 102 include sampling protuberance 102A in, sampling protuberance 102A is that end limit from sampling channel 105 protrudes out the centre of closing on this sampling perforation 101 in this, sample the relatively end wall of perforation 101 of interior sampling protuberance 102A has the breach 102B that samples in; Should be communicated with this sampling channel 105 by interior sampling breach 102B; Make the passage of this sampling channel 105 be able to extend centre, with the facility blood sampling, in other words near this sampling perforation 101; Interior sampling protuberance 102A is between this sampling perforation 101 and this sampling channel 105; And sample in being somebody's turn to do breach 102B and reaction zone 104 are to see through sampling channel 105 to connect, and the corpse or other object for laboratory examination and chemical testing 4 that the perforation 101 of sampling is gathered gets into from interior sampling breach 102B, and is sent to two reaction zones 104 through sampling channel 105; A corpse or other object for laboratory examination and chemical testing 4 carries out electrochemical reaction in reaction zone 104, detect signal to produce two groups.
See also Fig. 3; This sampling perforation 101 is to can be illustrated various formation aspect; And for example shown in Figure 4,1 of the similar detection test piece of formation of sampling protuberance 102A protrudes into as a circular perforations A (or other shape such as polygon, ellipse etc., this is that example is explained with the circular hole) side in this; And forming the protuberance 102A that should sample that is positioned at this circular perforations A scope, the last perforation of this circular perforations A partly is this sampling perforation 101; And the centre of the interior sampling breach 102B of the protuberance 102A that should interiorly sample and sampling perforation 101 is only apart from the X distance; Centre C (radius Y) than the more contiguous sampling perforation 101 in the border of this circular perforations A; Promptly should in the interior sampling breach 102B of sampling protuberance 102A front end be and contiguous this perforation center C in other position of sampling perforation 101 (non-be in this on sampling protuberance 102A); So mat should make the effect of drawing guiding blood better by interior sampling breach 102B, and the preferable distance of this X is 0.2mm～2mm.
In other embodiment; This detection test piece 1 is further to be provided with sample region 103 outside in the outside of this detection zone 10; Should outer sample region 103 include an outer sampling protuberance 103A, the sidewall of the protuberance 103A that samples outward is the outer sampling breach 103B that is provided with this sampling channel 105 of connection, and this outer sampling protuberance 103A plants acquisition mode as other; Can make blood through should outer sampling breach 103B, sampling channel 105 and this reaction zone 104 that arrives, have the effect of independent acquisition testing.In addition, this detection test piece 1 appropriate location around this kind perforation 101 is to be provided with at least one keeper 106, and this keeper 106 is to can be a perforation, otch or a projection, in order to cooperate the corresponding checkout gear 2 that uses, to reach the location of this detection test piece 1.
This Circuits System 11 is to have two groups of circuit connecting section 111 and two groups of detecting electrodes 112; This circuit connecting section 111 is positioned at the other end of this detection test piece 1 relative this detection zone 10; And connect this detecting electrode 112; Use and a checkout gear 2 electrical windings, detect signal to checkout gear 2 with transmission and analyze.This detecting electrode 112 is to be located at this reaction zone 104; Reaction zone 104 is transmitted by this detecting electrode 112 detect signal to checkout gear 2; This group detecting electrode 112 has a working electrode and a reference electrode at least, and this detecting electrode 112 is to connect this circuit connecting section 111 with lead 113.The quantity of sampling breach 102B, reaction zone 104, sampling channel 105 and detecting electrode 112 is two (or groups) in above-mentioned, is merely a preferred embodiment of the present invention, and these quantity can be more than one or two (or group), repeat no more in this.
Please consulting Fig. 5 in the lump, is the exploded view of the detection test piece of the first embodiment of the present invention.Detect the structure of test piece 1 in order to detailed exposure; Detect test piece 1 and comprise a substrate 12, a wall 13 and a upper cover plate 14; Substrate 12 is positioned at the detection zone 10 that detects test piece 1 and has substrate perforation 121; Have two reaction zones 104 around this substrate perforation 121; Substrate 121 both sides of boring a hole are provided with protuberance 122 in the substrate of corresponding two reaction zones 104, and protuberance 122 is that edge by substrate perforation 121 extends protrusion to substrate perforation 121 in each substrate, promptly protrudes out the centre near this substrate perforation 121.Moreover, be to be provided with this circuit connecting section 111, detecting electrode 112 and lead 113 on this substrate 12, these substrate 12 both sides are respectively to be provided with a substrate male part 123 in addition.
This wall 13 is covered in substrate 12, exposes the detection zone 10 and the circuit connecting section 111 of this detection test piece 1, this wall 13 have one detect usefulness channel spacing 131, this channel spacing 131 be with the substrate perforation 121 of substrate 12, substrate in protuberance 122 corresponding.When wall 13 was covered in substrate 12, this channel spacing 131 was these detection zones 10 that form this detection test piece 1 (14 of substrate 12 and upper cover plates).
This upper cover plate 14 is covered on the wall 13, this upper cover plate 14 have one with the 121 relative loam cakes perforation 141 of boring a hole of this substrate, this loam cake perforation 141 has the corresponding interior protuberance 142 of loam cake of protuberance in two sides and the substrate 122; In addition these upper cover plate 14 both sides be to should substrate male part 123 being to be provided with a loam cake male part 143, and in order to being combined to form this outer sampling protuberance 103A, and 123 of loam cake male part 143 and substrate male part are to form the breach 103B that should sample outward.
The detection test piece 1 of present embodiment is formed by substrate 12, wall 13 and upper cover plate 14 storehouses, and the repeating hole bit position of this substrate perforation 121, channel spacing 131 and loam cake perforation 141 forms the sampling perforation 101 that detects test piece 1.This channel spacing 131 makes protuberance 122 and this two interior sample region 102 of 142 formation of the interior protuberance of loam cake in this two substrate.This channel spacing 131 is in the sampling channel 105 of this substrate 12 and these sampling perforation 101 2 sides of 14 formation of upper cover plate, in order to sample region 102,101 and two reaction zones 104 of boring a hole of sampling in connecting.Moreover if during aforementioned keeper 106 perforation that should detect test piece 1, then this substrate 12, wall 13, upper cover plate 14 are corresponding respectively substrate orientation part 124, interlayer keeper 132, loam cake keepers 144 that are provided with perforated; If when this keeper 106 was otch, then this otch was a side (not shown) of being located at substrate 12, wall 13 or upper cover plate 14; If when this keeper 106 was projection, then this projection was to be located on substrate 12 or the upper cover plate 14 (not shown).
When blood is gathered in sampling perforation 101; Because sample region 102 is near sampling perforation 101 in being somebody's turn to do; Make a corpse or other object for laboratory examination and chemical testing 4 (or blood) can contact sampling breach 102B in this fast; This blood utilizes capillarity to see through this sampling channel 105 again and gets into two reaction zones 104, and makes this reaction zone 104 produce current signals and continue and transfer to this circuit connecting section 111 through this detecting electrode 112, lead 113.
See also Fig. 6 to Figure 11; In order to each layer combination and variation example of this detection test piece 1 to be described; Shown in Fig. 6, Fig. 6 A; This upper cover plate 14 and substrate 12 are respectively equipped with protuberance 122 in loam cake perforation 141, the interior protuberance 142 of loam cake and substrate perforation 121, the substrate, and protuberance 122 is big or small identical symmetry and is combined into sample region 102 in this in interior protuberance 142 of this loam cake and the substrate.Shown in Fig. 7, Fig. 7 A, the interior protuberance 122 of protuberance 142 and substrate is combined into sample region 102 in this in this loam cake for varying in size.Shown in Fig. 8, Fig. 8 A, the substrate of this substrate 12 perforation 121 is to be a circular hole and protuberance 122 in this substrate of tool not, and in the loam cake of this upper cover plate 14 protuberance 142 be form separately should in sample region 102.Shown in Fig. 9, Fig. 9 A, the loam cake of this upper cover plate 14 perforation 141 is to be a circular hole and protuberance 142 in this loam cake of tool not, and in the substrate of this substrate 12 protuberance 122 be form separately should in sample region 102.Shown in Figure 10, Figure 10 A; The loam cake of this upper cover plate 14 perforation 141 is to be a small sircle hole and protuberance 142 in this loam cake of tool not, and the zone of protuberance 122 and this loam cake perforation 141 and 121 of this substrate perforation is that common formation should interior sample region 102 in the substrate of this substrate 12.Shown in Figure 11, Figure 11 A; The loam cake of this upper cover plate 14 perforation 141 is to be a small sircle hole and protuberance 142 in this loam cake of tool not; And the substrate of this substrate 12 perforation 121 is to be a protuberance 122 in this substrate of tool than big hole and not; Wherein this loam cake perforation 141 is and this substrate perforation 121 position, hole for varying in size, and the zone of this loam cake perforation 141 and 121 of this substrate perforation is that form should interior sample region 102.In aforementioned variant, in this sampling protuberance 102A for protuberance 142 in the loam cake on protuberance in the substrate on this substrate 12 122 and this upper cover plate 14 distinctly or matched combined formed; Should in sample region 102 be to can be sampling protuberance 102A in this and form by this substrate perforation 121 of position, different hole size distinctly regional or matched combined with 141 of this loam cake perforation; This sampling perforation 101 is formed by the repeating hole bit position of this substrate perforation 121 and loam cake perforation 141, and its pitch-row is 0.4mm～4mm.
Seeing also Figure 12, Figure 13, is the user mode figure of the first embodiment of the present invention.As shown in the figure, the detection test piece 1 that first embodiment is provided is mainly used in a checkout gear 2 with sampling and measuring ability.Checkout gear 2 has a sampling module 21 and a detection module 22, and sampling module 21 is positioned at a side of detection module 22, and supplies a blood taking needle 23.Detection module 22 has a test piece slot 221; Test piece slot 221 is the semi open model slot; Its circuit connecting section 111 that supply to detect test piece 1 plugs the location, is that a end with tool circuit connecting section 111 is plugged into this test piece slot 221 toward detection module 22 directions by sampling module 21 and detect test piece 1.Have an electric connector 222 in the test piece slot 221, make the circuit connecting section 111 that detects test piece 1 insert the electric connector 222 of contact test piece slot 221.Again, be that facility should detect assembly and disassembly operation of test piece 1, the front end that this detections test piece 1 is close to this detection zone 10 is can prolong and form a grip part 107.
The sampling module 21 of this checkout gear 2 has a sampling portion 211 and a bar portion 212; The loading and unloading setting that bar portion 212 supplies blood taking needle 23; And utilize elastic force to make blood taking needle 23 stretch out sampling portion 211 from moving, and the tested position 3 that punctures person to be measured with adopt a corpse or other object for laboratory examination and chemical testing 4 (like blood).The below of sampling portion 211 has a sampling opening 211A, and sampling opening 211A supplies blood taking needle 23 to pass.Moreover; These sampling portion 211 bottoms are that at least one test piece keeper 211D is set around sampling opening 211A; Test piece keeper 211D is to the keeper 106 that should detect test piece 1, and is as shown in the figure, and this test piece keeper 211D and keeper 106 are the corresponding embodiment that are projection and perforation.
Figure 13, shown in Figure 14 and for example; This checkout gear 2 (sampling portion 211) bottom is can further be provided with paired sampling to compress male member 211B; Sampling compresses male member 211B and is arranged at around the sampling opening 211A; This sampling compresses male member 211B and can be male members such as strip, arc strip, and the sampling of present embodiment compresses to have two and compress breach 211C between male member 211B, two compress the corresponding sampling that detects test piece 1 of breach 211C bore a hole 101 both sides two in sampling protuberance 102A.
After the circuit connecting section 111 that detects test piece 1 is inserted in test piece slot 221; Be positioned at the detection zone 10 that detects test piece 1 to the sampling opening 211A of sampling portion 211 near; Make and be positioned at the keeper 106 that sampling opening 211A test piece keeper 211D on every side is inserted in detection test piece 1; In checkout gear 2 belows, make the corresponding exactly sampling perforation 101 that detects test piece 1 of sampling opening 211A in order to the detection zone 10 of detection and localization test piece 1, pass the sampling of puncturing exactly for blood taking needle 23.And the grip part 107 of this detection test piece 1 front end makes the installing of convenient this detection test piece 1 and takes off operation for protruding out this checkout gear 2 front ends (or both sides).During detection; Because this sampling compresses male member 211B and passes sampling perforation 101 protrusions; In order to compress person's to be measured tested position 3, tested position 3 is squeezed,, blood taking needle 23 can accelerate a corpse or other object for laboratory examination and chemical testing 4 leaching rates when puncturing person's to be measured tested position 3; And enough corpse or other object for laboratory examination and chemical testing amounts are provided; By two interior these sampling channels 105 of breach 102B entering of sampling of sampling perforation 101 both sides, after a corpse or other object for laboratory examination and chemical testing 4 flow to two reaction zones 104, checkout gear 2 provided a voltage to produce one and detects signal a corpse or other object for laboratory examination and chemical testing 4 with promptly at this moment; The circuit connecting section 111 that this detection signal see through to detect test piece 1 is sent to detection module 22, and detection module 22 analyzing and testing signals are with the concentration that obtains a corpse or other object for laboratory examination and chemical testing 4 and the data of correlation behavior.
See also Figure 15 to Figure 18; In order to the alternate embodiment of explanation detection test piece 1, this detection test piece 1 is to be provided with one to compress protruding part 108 around this sampling perforation 101, and this compresses protruding part 108 is to be a ring-type convex body (or other shape); This compresses the tested position 3 that protruding part 108 contact downwards compresses person to be measured during use; After treating that blood taking needle 23 passes sampling perforation 101, impel the corpse or other object for laboratory examination and chemical testing 4 at tested position 3 to ooze out fast, so that enough corpse or other object for laboratory examination and chemical testing amounts to be provided.This compress protruding part 108 can be located at this substrate perforation 121, this channel spacing 131 (not shown) or this loam cake perforation 141 around, wherein this height that compresses protruding part 108 is 0.01mm～2mm.Among aforementioned Figure 15 to Figure 17, the protruding part 108 that compresses of this detection test piece 1 is to be located on this upper cover plate 14 and outwards to be protruded by this upper cover plate 14, is with this detection test piece 1 upset during use, makes this compress protruding part 108 and compresses tested position 3; And in Figure 18, the protruding part 108 that compresses of this detection test piece 1 is to be located on this substrate 12 and outwards to be protruded by this substrate 12, can reach the effect that 1 pair of tested position 3 of test piece compresses sampling that detects equally.
Above-mentionedly know; The present invention provides a kind of detection test piece; This detection test piece is to utilize Electrochemical Detection, and it is in the interior sample region that sampling perforation setting can be gathered a guiding corpse or other object for laboratory examination and chemical testing, and the interior sampling breach on the interior sample region is easy to draw and a guiding corpse or other object for laboratory examination and chemical testing gets into reaction zone generation electrochemical reaction.This detection test piece more can be provided with around the sampling perforation and compress protruding part, compresses the tested position that protruding part can compress person to be measured, gets into reaction zone to quicken a corpse or other object for laboratory examination and chemical testing to ooze out from tested position and produces electrochemical reaction.The present invention more provides a kind of checkout gear of the detection test piece of the present invention of arranging in pairs or groups, the function that this checkout gear has sampling simultaneously concurrently and detects, and it is simple in structure, effectively reduces cost; In addition, be separated with this detection test piece between sampling portion and testee during owing to use, can be disposable use, remove the aleopation between the person of avoiding the use of through disposable operation technique means, so that sanitarian use to be provided and detect test piece.
In sum; Be merely preferred embodiment of the present invention; Be not to be used for limiting the scope that the present invention implements, all equalizations of doing according to the described shape of claim scope of the present invention, structure, characteristic and spirit change and modify, and all should be included in the claim scope of the present invention.
Claims (19)
1. one kind is detected test piece, it is characterized in that, be to comprise:
One detection zone, this detection zone is to have:
One sampling perforation;
At least one sampling channel is to the perforation of should sampling;
At least one reaction zone is positioned at this sampling channel; And
Sample region in one, be positioned at this sampling perforation around, end limit of sample region is provided with sampling breach in this, being communicated with should sampling perforation and this sampling channel; And
One Circuits System, it electrically connects this reaction zone.
2. detection test piece as claimed in claim 1 is characterized in that, more comprises:
One substrate, this substrate have substrate perforation;
One wall is covered in this substrate, and this wall has a channel spacing, and this channel spacing is to boring a hole by substrate; And
One upper cover plate is covered in this wall, and this upper cover plate has loam cake perforation;
Wherein the repeating hole position of this substrate perforation, this channel spacing and the perforation of this loam cake is to form this sampling perforation; Be to form this sampling channel between this channel spacing and this substrate, this upper cover plate.
3. detection test piece as claimed in claim 2; It is characterized in that; Should interior sample region be at least one interior sampling protuberance wherein; Between this sampling perforation and this sampling channel, sampling protuberance is from this sampling channel protrusion to be extended to this sampling perforation in the end limit of the perforation of should sampling in this, and sampling protuberance is formed by protuberance in the loam cake on protuberance in the substrate on this substrate or this upper cover plate in this.
4. detection test piece as claimed in claim 3 is characterized in that, wherein should in front end of sampling protuberance be that the centre distance of boring a hole with this sampling is 0.2mm～2mm.
5. detection test piece as claimed in claim 2 is characterized in that, wherein this loam cake perforation is and this hole position of substrate perforation for varying in size, and the zone between this loam cake perforation and the perforation of this substrate is to form sample region in.
6. detection test piece as claimed in claim 5 is characterized in that, wherein the pitch-row of this sampling perforation is 0.4mm～4mm.
7. detection test piece as claimed in claim 5; It is characterized in that; Wherein should interior sample region more include at least one interior sampling protuberance; Between this sampling perforation and this sampling channel, sampling protuberance is from this sampling channel protrusion to be extended to this sampling perforation in the end limit of the perforation of should sampling in this, and sampling protuberance is formed by protuberance in the loam cake on protuberance in the substrate on this substrate or this upper cover plate in this.
8. detection test piece as claimed in claim 1 is characterized in that, is to be provided with at least one protruding part that compresses around this sampling perforation.
9. detection test piece as claimed in claim 1 is characterized in that, more comprises at least one keeper, and wherein this keeper is a perforation, a kerf or a projection.
10. detection test piece as claimed in claim 1 is characterized in that, it further comprises at least one outer sample region, and this outer sample region is the outside that is positioned at this detection test piece, and this outer sample region is to be communicated in this sampling channel.
11. one kind is detected test piece, it is characterized in that, be to comprise:
One detection zone, this detection zone is to have:
One sampling perforation;
At least one sampling channel is to the perforation of should sampling;
At least one reaction zone is positioned at this sampling channel; And
At least one protruding part that compresses, be located at this sampling perforation around; And
One Circuits System, it electrically connects this reaction zone.
12. detection test piece as claimed in claim 11 is characterized in that, more comprises:
One substrate has substrate perforation;
One wall is covered in this substrate, and this wall has a channel spacing, and this channel spacing is to boring a hole by substrate; And
One upper cover plate is covered in this wall, and this upper cover plate has loam cake perforation;
Wherein the repeating hole position of this substrate perforation, this channel spacing and the perforation of this loam cake is to form this sampling perforation, is to form this sampling channel between this channel spacing and this substrate, this upper cover plate.
13. detection test piece as claimed in claim 12 is characterized in that, wherein this compresses protruding part and is located at around the perforation of this substrate, this channel spacing or the perforation of this loam cake.
14. detection test piece as claimed in claim 12 is characterized in that, wherein the pitch-row of this sampling perforation is 0.4mm～4mm.
15. detection test piece as claimed in claim 11 is characterized in that, wherein this height that compresses protruding part is 0.01mm～2mm.
16. detection test piece as claimed in claim 12; It is characterized in that; Wherein be to be provided with at least one interior sampling protuberance between this sampling channel and this sampling perforation; Should interior sampling protuberance be from this sampling channel the end limit of the perforation of should sampling to be extended to this sampling perforation to protrude, end limit of sampling protuberance be to be provided with sampling breach in this, and this interior sampling protuberance is formed by protuberance in the loam cake on protuberance in the substrate on this substrate or this upper cover plate.
17. detection test piece as claimed in claim 16 is characterized in that, wherein should in front end of sampling protuberance be that the centre distance of boring a hole with this sampling is 0.2mm～2mm.
18. detection test piece as claimed in claim 11 is characterized in that, more comprises at least one keeper, this keeper is a perforation, a kerf or a projection.
19. detection test piece as claimed in claim 11 is characterized in that, it further includes at least one outer sample region, and this outer sample region is the outside that is positioned at this detection test piece, and this outer sample region is to be communicated in this sampling channel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201110035608.4A CN102613978B (en) | 2011-01-31 | 2011-01-31 | Detection test piece |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110035608.4A CN102613978B (en) | 2011-01-31 | 2011-01-31 | Detection test piece |
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| CN102613978A true CN102613978A (en) | 2012-08-01 |
| CN102613978B CN102613978B (en) | 2014-12-03 |
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| CN201110035608.4A Expired - Fee Related CN102613978B (en) | 2011-01-31 | 2011-01-31 | Detection test piece |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI735137B (en) * | 2019-08-02 | 2021-08-01 | 華廣生技股份有限公司 | Physiological signal sensing device |
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| CN102613978B (en) | 2014-12-03 |
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