CN102609626A - Intelligent medical service system based on RFID (radio frequency identification devices) and CDM (code division multiplex) technologies - Google Patents

Intelligent medical service system based on RFID (radio frequency identification devices) and CDM (code division multiplex) technologies Download PDF

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CN102609626A
CN102609626A CN2012100665576A CN201210066557A CN102609626A CN 102609626 A CN102609626 A CN 102609626A CN 2012100665576 A CN2012100665576 A CN 2012100665576A CN 201210066557 A CN201210066557 A CN 201210066557A CN 102609626 A CN102609626 A CN 102609626A
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medicine
intelligent
medical
patient
rfid
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郑立荣
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Fudan University
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Fudan University
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Abstract

The invention belongs to the technical field of wireless communication, and particularly relates to an intelligent medical service system based on RFID (radio frequency identification devices) and CDM (code division multiplex) technologies, which comprises a sensor data acquisition layer, a medical resource management layer and an intelligent medical service provision layer. Different modules of the sensor data acquisition layer are integrated inside an intelligent medicine kit to serve as a household intelligent terminal which is combined with the RFID sensor technology and the CDM material technology and supports various sensor networks, the wireless network and 3G (generation)/4G networks. Besides, one end of the intelligent terminal is connected with the intelligent medical service provision layer which serves as the upper layer, and the other end of the intelligent terminal carries out private self-services including dosing reminding and recording, intelligent drug package control, sign parameter acquisition recording, emergency alarming and remote acquisition of doctor suggestions. The intelligent medical service system is capable of changing the 'hospital-centered and doctor-centered' nursing mode into the 'household-centered and patient-centered' nursing mode, and accordingly self-nursing efficiency and reliability of patients are improved remarkably and medical resources are saved greatly.

Description

A kind of intelligent medical service system based on RFID and CDM technology
Technical field
The invention belongs to wireless communication technology field, be specifically related to a kind of intelligent medical service system based on RFID and CDM technology.
Background technology
One, The traditional medical pattern and the wasting of resources thereof
At present, domestic hospital adopts the traditional medical pattern mostly, and patient's attendance and recuperation all carries out in hospital, needs the labor manpower financial capacity.Especially chronic lacking specialty effectively under the situation of " family-hospital " communication mode, usually can't feel at ease to be in to recuperate, and causes that a large amount of medical resources are occupied, the performance of medical care effectiveness is low.
Simultaneously, the uncomplaisance phenomenon of taking medicine also frequently takes place, main cause have doctor patient communication untimely, understand deviation arranged, the elderly's decrease of memory, the young people ignores the doctor's advice and the state of an illness etc.It gently then causes a large amount of wastes of medicine, and is heavy then influence result of treatment, increases unnecessary disease relapse and further consultation number of times, is the key factor that causes the medical resource waste.
Data presentation, the medical resource waste of China reaches the 165%-170% that the government finance medical treatment drops into to the 30%-40% that accounts for hospital's total expenses.If find the method that effectively to avoid the wasting of resources, just can practice thrift medical treatment cost, improve the medical resource distribution, alleviate the conflict between doctors and patients that is on the rise.
Two, Present technology and limitation thereof
The general communication technology is being brought into play enormous function aspect the medical resource practicing thrift, the HIS and the pcs system that adopt like a large amount of front three hospital.This system carries out information system management to the basic medical treatment data, makes medical personnel in time inquire patient's diagnosis and therapy recording, and stores easily, files.And for example the RFID location technology is sticked unified electronic tag in apparatus, personnel, the place of hospital internal, convenient location, searching, distribution, management.
Though this type technology has promoted the efficiency of management of hospital to a certain extent, all there is serious environment for use limitation---with the hospital center.For individual patient, how to guarantee in home environment, to take medicine on time and to keep daily monitoring same very crucial.Still lack a kind of robust techniques at present, can control drug packaging through analyzing prescription, thus the strict flow process of taking medicine that limits medicine time, standard patient.The communication technology should fundamentally change the communication way between " patient " and " hospital "; Set up a kind of reliable means of communication of hommization; Extend to family to part diagnosis and nursing, monitoring observation from hospital, solve the problem of patient from the source excessively the taking of medical personnel, a large amount of medicine serious waste.
Summary of the invention
The object of the present invention is to provide and a kind ofly can practice thrift medical resource, optimize medical control, make things convenient for the intelligent medical service system of patient treatment.
The intelligent medical service system that the present invention proposes is based on a kind of brand-new " the self-service nursing of patient " theory, relies on the three-layer network communication system to realize.This intelligent medical service system can be divided into sensing data acquisition layer, medical resource administration and supervision authorities and intelligent medical service provides layer.Wherein:
The sensing data acquisition layer is made up of the module that data acquisition equipment, data counting device, data storage device, data transmission set and medicine opertaing device etc. have the difference in functionality effect.Wherein, Data acquisition equipment has not only comprised existing conventional medical data acquisition equipment; Like instrument for measuring blood pressure and heart rate measuring instrument, also comprised the novel data acquisition equipment that combines with new technology, like the read-write RFID label that is used to gather patient's MAR of the present invention's initiative.Data counting device and Data Holding Equipment are responsible for that image data is carried out a series of science and are calculated, and extract, keep and integrate valid data, to improve terseness, the readability and professional of data.Data transmission set is a media with the multiple network technology, and the data after integrating are sent to the medical resource administration and supervision authorities, is to realize basis effectively interactive between the doctors and patients.
Among the present invention; Each module of said sensing data acquisition layer is done the as a whole inside that is integrated in intelligent medicine box; Become a kind of family intelligent terminal, it has combined RFID sensing technology, CDM material technology, supports various kinds of sensors network, wireless network, 3G/4G network; One end of intelligent terminal can connect upper strata public service platform (like hospital, clinic, first-aid centre, pharmaceutical production chain etc.); The other end of intelligent terminal can be realized private Self-Service (obtaining etc. as medication alert and record, intelligent drug packaging control, sign parameter acquisition record, emergency situations alarm, doctor's suggestion are long-range), is equivalent to a small-sized health care station in the patient family.
The intelligent medical service provides the net background of layer as intelligent medicine box, mainly comprises professional medical mechanisms such as hospital, first-aid centre, medicine supply chain etc.These medical mechanisms need have extensive and abundant software support as serving the provider, to guarantee to realize systemic-function.Wherein, hospital can provide the service of sign parameter monitoring, prescription download service, healthy newspaper Push Service, the subscription services of seeking medical advice, remote diagnosis service etc.; First-aid centre can provide first aid alarm monitoring service etc.; The medicine supply chain can provide medicine true and false inquiry service, medicine explanation inquiry service etc.The service provider can set, change, expand service content according to actual needs, and the intelligent medicine box terminal can be accomplished service synchronization work automatically.
The medical resource administration and supervision authorities provide the transition auxiliary layer of layer as sensing data acquisition layer and medical services, mainly are responsible for the unified monitoring and control of system, manage the distribution medical resource with the science mode, promote its operational paradigm.Because the specialty support that mechanism of every family provides has nothing in common with each other; The medical resource administration and supervision authorities need be discerned the information that the data acquisition layer is submitted, add up, screening, classification processing; And according to patient's different demands; Be sent to corresponding medical services provider, the information processing efficiency and the feedback efficiency of serving the provider with raising.For example; The general signs parameter information can be transferred into hospital's Control Room; When the doctor finds that through analyzing the sign parameter being clearly better appears in patient's the state of an illness, will open the new edition prescription in view of the above and push to intelligent medicine box, intelligent medicine box can remind the patient to note content update after receiving prescription information immediately.But when big ups and downs appear in patient's sign parameter, and when surpassing preset alarm value, represent the patient emergency to occur, be in urgent need of help.Intelligent medicine box can send the alert data bag that carries geographical location information and sign information immediately, and resource management layer can be sent to first-aid centre, in the hope of obtaining medical aid fast.
More than three layers of platform Each performs its own functions, the realization concrete function that is linked has been formed a complete intelligent medical service system, make between patient and the hospital contact more closely, interaction is more frequent, helps to promote therapeutic efficiency.
Said intelligent medicine box is arranged in the data collection layer of intelligent medical service system, integrated sensing equipment, computing equipment, memory device, transmission equipment and medicine opertaing device.Its appearance design is the white casing of 25cm X 20cm X 15 cm, and handle is equipped with in the top cover outside, is printed on the Red Cross sign on the casing.1 shift knob (ON/OFF), 2 RS232 interfaces, 1 USB interface, 1 SD socket, 1 sim card slot, 1 Ethernet interface, 1 infrared scanner and 1 tripod ac plug are equipped with in the casing outside.Space in the medicine-chest is the branch bar, is convenient to the medicine classified and stored.Medicine-chest top cover inside is embedded with touch LCD screen and 1 boombox of 1 10.1 inches.Hardware device in the intelligent medicine box comprises that 32bit XscaleCPU, WAN adapter, UHF RFID antenna and reader, Zigbee monolithic converter, WIFI antenna, WIFI unit, lcd touch display screen, loudspeaker and corresponding C # write application software.Medicine-chest supports GSM/GPRS communication to communicate by letter (domestic: TD-SCDMA with 3G network; Europe: WCDMA), concrete standard is:
WCDMA:
(1.HSDPA 7.2Mbps is descending), HSUPA (5.76Mbps is up)
(2.UMTS 384kbps last/descending)
(3.EDGE 236.8kbps last/descending) 800/1700/2100MHz bandwidth
TD-SCDMA:
(1.TD-HSDPA 2.8Mbps is descending) 1900/2100MHz bandwidth
Because the function singularity of intelligent medicine box; The RFID signal must be strapped in box house by strictness; Here taked a kind of metal electric magnetic shielding mode: promptly on three casings of intelligent medicine box, stick metal screen layer, anti-stop signal leaks, and only reserves one side and communicates by letter with the external world.Simultaneously, the antenna of rfid interrogator is the U type and is uniformly distributed at the bottom of the case, makes it can evenly read the medicine RFID label signal of any position in the case.
The hardware structure of intelligent medicine box is a kind of netted multicore architecture (multi-core system based on 2D-Mesh-NoC) that is integrated on the chip; Mainly form, be respectively trunk system (intelligent medicine box) and from part system (intelligent sensing label, intelligent drug packaging) by two parts.Wherein, trunk system is supported nine big functions: audio frequency, video, WAN, WSN, instant ECG, examine in advance immediately, task management, RFID manage and other instant projects.Each function all has dedicated cpu processor, converter and hardware cell separately, builds the interconnect architecture of multinode jointly.Be divided into " intelligent sensing label " and " intelligent drug packaging " two parts from the part system." intelligent sensing label " is made up of sensor, microprocessor MCU, battery, radio frequency converter and antenna, and " intelligent drug packaging " is made up of CDM array, battery, DC-DC converter, energy harvester, FSM, radio frequency converter and antenna.Carry out radio communication from the part subsystem through antenna and trunk system (being intelligent medicine box), accept the unified distribution management.
Intelligent medicine box has a supporting RFID magnetic card, is writing down user's personal information, and the user can be through the operation login medicine-chest system that swipes the card.Medicine-chest is after the ID that has read the patient number; Communicate through 3G network and server; Retrieve also downloading patient information, information about doctor, prescription information from hospital's SQL database (be arranged in medical services layer is provided) of correspondence, and store in the storer, keep regular update.
In the electronics prescription that the doctor provides, should comprise following data: patient should take medicine article ID, the quantity of taking medicine and the time set table of taking medicine.When needs generate complete prescription and supply the patient to download, system will inquire about drug data bank automatically, according to information such as the title of medicine ID coupling medicine, model, coding, specifications.These information should be identical with the data that pharmaceutical production manufacturer provides, and after medicine was placed into intelligent medicine box, medicine-chest just can carry out the data comparison, accurately identifies the medicine that the patient buys like this.
After medicine is placed into intelligent medicine box; The distributed U type rfid interrogator antenna of bottom half will refresh mode through fixed frequency and read the RFID label on the packing; Note the medicine information that is pre-stored in wherein, and verify comparison with the electronics prescription that the doctor provides.When having medicine of the same race in the comparison result shows electronics prescription, intelligent medicine box can be accomplished a series of registrations, record, inquiry, analytical work on the backstage, realizes drug control intellectuality, robotization, systematization.
Simultaneously, intelligent medicine box can also communicate with the pharmaceutical production merchant, obtains the complete production procedure information of this medicine, thereby effectively discerns counterfeit drug, guarantees patient's personal safety.
After the intelligent medicine box completion is operated correspondence, affirmation, the typing of medicine and prescription, just change over to and carry out the medication alert function.At first, LCDs will show the detailed information of taking medicine.Bright color, succinct design have been adopted in main interface, and the patient is come into plain view, and color and font can reset according to patient's hobby.The interface title block comprises three information, is respectively " patient's name ", " date (left and right sides arrow is in order to page turning) " and " time ", sinks to the bottom the hurdle and then comprises doctor's name, doctor's contact method and doctor's advice.The master meter lattice of interface center according to the time descending sort patient all medicines and the medication remarks that need take the same day, every kind of medicine occupies delegation, every row comprises three row, is respectively medicine name, medicine time and single and takes deal.Having taken medicine has smiling face's mark before capable, does not take medicine and does not mark, and the next item down waits to take medicine then with the bright capable form enlarged and displayed of height.
When the system time of intelligent medicine box has arrived the medicine time of stipulating in the electronics prescription, medicine-chest will initiatively remind the patient to take medicine.Prompting function has taken into full account the physiological defect of a part of main body among the patient in design; Like the elderly, blind person and the deaf-mute deficiency on hearing, eyesight; It realizes prompting function by abundant multimedia means, sends the sound or music, makes patient's intelligent label on one's body send vibrations etc. as using touching display screen, screen flicker, light flash, loudspeaker.
After the patient obeys following medicine, can be through the interactive button on the screen to medicine-chest feedback information (the YES representative to have been taken, and the NO representative is not taken), intelligent medicine box can write down the details of taking medicine in view of the above and feed back to the doctor.
In addition; For the strict medicine that is used to treat the severe chronic disease that limits the medicine time and the quantity of taking medicine of needs; CDM technology and RFID technology are adopted in drug packaging; Promptly adopt intelligent drug packaging, intelligent medicine box can be controlled drug packaging, and detail record patient time, kind and the deal of taking medicine.
This intellectuality drug packaging; Promptly based on the technological intelligent drug packaging system of CDM technology and RFID; Constitute by CDM material, RFID label, rfid interrogator, near field coil, direct current transducer, battery, medical card and microcircuit; Can accept the RFID instruction control, to patient's various drug taking behaviors (comprising correct step and violation operation) detect automatically, record, comprise open packing, clothes down medicine, forget and take medicine, damage medicine, abandon medicine etc.; The medicine time and the deal that can also guarantee medicine all receive strict control, phenomenon that effective prevention is taken medicine in advance or excess is taken medicine.
Key component as intelligent drug packaging; CDM (controlled delamination material) presents " aluminium foil---epoxy adhesive---aluminium foil " three-decker; Two-layer up and down aluminium foil is connected to the voltage output end and the earth terminal of monitor respectively, and epoxy adhesive has superstrong adhesive, can bear 211 kg/cm2 (21Gpa) pressure under the normal temperature; The tightly adhesion of whole trilaminate material is difficult to be stripped from destruction.It is used to substitute traditional individual layer In Aluminium Foil Packing and is attached on the edge of conventional package, on the aluminium foil that for example capsule seals.The voltage of only working as between the two-layer aluminium foil surpasses threshold value Td above threshold value Vd and duration, and it is softening that epoxy adhesive just can produce electrochemical reaction, if do not receive open command, the patient can't open with external force without authorization.
Also be printed on a RFID label in the drug packaging, the details of medicine have been stored in the inside.Medicine is placed in the intelligent medicine box under the normal condition, and the rfid interrogator antenna at the bottom of the case can read this label repeatedly with fixed frequency, to confirm that medicine exists.This label technique has combined CMOS integrated circuit and coil antenna, and way to take power is that antenna is placed in the electromagnetic field, and can from the electromagnetic field of the same area, obtain major clock.Through opening and closing modulating current, chip will send it back ID number of 8 Manchester's cdes and be stored in the preprogrammed memory array.In order to satisfy the two-way communication requirement of system, the present invention adopts two generation RFID.
Rfid interrogator is the integrated RFID transceiver circuit of CMOS.Rfid interrogator has no external crystal oscillator, obtains to be suitable for the resonant frequency of antenna through inner phase-locked loop pll.It makes antenna be operated in carrier frequency as the base station, and aerial signal is carried out amplitude modulation synchronous modulation and demodulation, and realizes and microprocessor communication through simple interface.It is driven by the 5V direct supply, is operated in low frequency 100 kHz to 150 kHz.
The input voltage range of charge pump current mode pulse width modulated step-up DC-DC converter is from 2.5V to 10V, and adjustable output voltage is up to 30V.Because have only 3V from the output voltage of single-chip microcomputer, the DC voltage that a controlled delamination material require of general open 20V is above, if charge pump is launched, it can rise to voltage 30V and issue packing from 3V.
Medical card is a big capacity, programmable two generation RFID labels.Before receiving the information of medical package, medical card is in off working state.When receive from rfid interrogator read signal the time, medical card is activated, and sends out ID number.If ID number meets, medical package sends another reading command to medical card, and medical card can send to packing with all medication information of patient subsequently.At last, when the information that stores in the packing changes with medical card near, can obtain the interior lastest imformation of packing.
Owing in the drug packaging RFID chip is housed; And the rfid interrogator antenna at the bottom of the case can read all labels in the medicine-chest repeatedly with fixed frequency; So when medicine is taken out by the patient; Rfid interrogator can be found immediately and lack any medicine, and the information of taking medicine and the current time stored in advance in the inquiry medicine-chest.If feedback information shows that the patient is current and should take this kind medicine; Then system can choose which pill of opening on the tablet package according to certain rule; And be presented at the form of mimic diagram and inform the patient on the main screen, send open command through rfid interrogator one to drug packaging again.Resonance coil in the drug packaging receives this open command, delivers MCU and accomplishes information processing.The 3V voltage transitions that MCU controls the DC-DC converter subsequently provides battery is 30V or higher (greater than turn-on threshold voltage Vd) and keeps one section threshold time Td.Epoxy adhesive dissolves under the voltage effect, and the patient just can take out medicine voluntarily, has avoided excess and the phenomenon of taking medicine in advance.
Be printed on microprinting circuit and selector switch in the CDM drug packaging.Selector switch makes medicine can gradation controlled, and print circuit can be confirmed the current state of medicine, and concrete mode is: when medicine did not take out as yet, the CDM material was perfect, and print circuit all is communicated with, and current signal exists.After certain medicine was removed, this regional CDM material was damaged, so print circuit that should the zone also cuts off current vanishes thereupon.The current signal of disappearance can mark amount of pills and the position that the patient had taken; And the transmit antenna feedback of passing through on the packing is given medicine-chest; As choose the reference of opening which pill next time, also can feed back to the doctor simultaneously, the proof of on time taking medicine according to quantity as the patient.
In addition, when making intelligent drug packaging, the RFID labeling requirement is attached on the aluminium foil, and the EPC C1G2 label of standard can be fallen original signal by the electromagnetic wave shielding of aluminium foil reflection under the situation of not carrying out anti-metal interference performance reinforcement.Here take a kind of solution, promptly print printing antenna exposed, that do not contact aluminium foil, make signal be able to normal transmission and receive at the packing edge.This method is applicable to the wireless power supply type CDM packing with aluminum foil outer layer too.
Except intelligent drug packaging, combined with intelligent label technique, intelligent medicine box also possess daily monitoring function.The patient wears the intelligent label iTag of specialty on one's body; Communicate by letter with intelligent medicine box with radio sensing network WSN; Can monitor patient's daily behavior, body parameter at any time, like cardiogram, blood pressure, the oxygen content of blood, breathing oxygen content, blood-sugar content, shell temperature etc.All heat transfer agents can regularly be pushed to the Control Room of hospital, are monitored in real time by medical personnel.If the patient does not feel well, also can press convenient pushbutton enable voice recognizer, say the subjective feeling of oneself and send to hospital to audio-frequency information, seek doctor's help.
In addition; Intelligent medicine box is built-in with the reliable instant data processing algorithm through experimental demonstration, can examine in advance for the patient carries out the basis in the very first time, first place according to collecting the sign health parameters; Provide reasonable suggestions, and valuable advisory opinion is provided for follow-up seeking medical advice.Tradition is examined immediately in advance because medical facilities scarcity or medical personnel distribute deficiency, and the efficient quality is low relatively, and the appearance that intelligence is examined immediately in advance will greatly improve this situation.Intelligent medicine box can also be integrated a series of violation operation records, body parameter Monitoring Data, patient's subjective feeling and examine the result immediately in advance, is sent to public service platform, to obtain doctor specialty feedback and guidance timely.Simultaneously; Intelligent medicine box remains with the service platform of first-aid centre and communicates by letter; In case the intelligent label that the patient wears on one's body monitors emergency condition, like acute allergic reaction, miocardial infarction etc., intelligent medicine box can send the alarm of seeking help (or controlled give the alarm by patient oneself) in the very first time.This alarm comprises patient position, state of an illness type information, can assist first-aid centre to launch targetedly efficiently relief.This function can effectively be avoided alone sufferer of being in to miss the warning chance, incur loss through delay treatment.Simultaneously, emergency physician only need be inquired about intelligent medicine box, just can obtain patient's take medicine record and body parameter record in the past, as the valuable material that rescues.
Description of drawings
Fig. 1 is the three-layer network communication structure of intelligent medicine box.
Fig. 2 is the concrete function of intelligent medicine box.
Fig. 3 is the appearance design of intelligent medicine box.
Fig. 4 is the inner structure of intelligent medicine box.
Fig. 5 be intelligent medicine box use the householder interface.
Fig. 6 is the multi-core network framework (trunk portion) of intelligent medicine box.
Fig. 7 is the three-decker of CDM material.
Fig. 8-9-10 is the structure of intelligent drug packaging.
Figure 11 is the hardware configuration of intelligent label.
Figure 12 is the structure of two generation RFID labels.
Figure 13 is the Card Reader open-type flow process of intelligent drug packaging.
Figure 14 is the SQL major key and generation form of electronics prescription.
Label among the figure: 1 is the RFID antenna; 2 is the RFID card reader; 3 is the WIFI unit; 4 is the WIFI antenna; 5 is loudspeaker; 6 is the LCD backlight; 7 is CPU; 8 is the 2.4G antenna, the Zigbee unit; 9 deposit the hurdle for medicine; 10 is metal screen layer; 11 is LCD display.
Embodiment
Further describe the present invention below in conjunction with accompanying drawing and example.
Fig. 1 is the three-layer network communication structure of intelligent medicine box.
Wherein, data collection layer is made up of data acquisition equipment, data computation memory device, data transmission set etc., is integrated in intelligent medicine box device inside, is equivalent to a kind of family intelligent terminal; The medical resource administration and supervision authorities mainly are responsible for the unified monitoring and control of system as the transition auxiliary layer of the 1st layer and the 3rd layer, manage the distribution medical resource with the science mode, promote its operational paradigm; Medical services provide the net background of layer as intelligent medicine box, are the bases of realizing repertoire, and according to different concrete needs, this layer will be provided by hospital, first-aid centre, medicine supply chain etc. respectively.
Fig. 2 has showed the concrete function of intelligent medicine box.Intelligent medicine box is deposited medicine and prescription, accomplishes medication prompting and record; Intelligent label is worn on one's body the patient, the monitoring health parameters; Intelligent packaging receives the medicine-chest instruction control, the standard flow process of taking medicine; Medicine-chest is connected with the service platform that pharmaceutical production chain, first-aid centre, hospital provide; Tracking to the pharmaceutical production chain can prevent counterfeit drug; Can replace manual work to dial 120 to the automatic warning of first-aid centre, regularly transmit, refresh the patient's body parameter and can make things convenient for the doctor to monitor patient's health status to hospital database.
Fig. 3 is the appearance design of intelligent medicine box.The casing rectangular parallelepiped that is white in color is equipped with handle and hasp, and the center is printed on the Red Cross mark.1 shift knob (ON/OFF), 2 RS232 interfaces, 1 USB interface, 1 SD socket, 1 sim card slot, 1 Ethernet interface, 1 infrared scanner and 1 tripod ac plug are housed on the casing.
Fig. 4 is the unpacking cut-away view of intelligent medicine box.Casing the latter half is deposited hurdle, metal screen layer (3 face) and U type RFID antenna by medicine and is formed.The casing first half is made up of 32bit XscaleCPU, WAN adapter, UHF RFID antenna and reader, Zigbee monolithic converter, WIFI antenna, WIFI unit, lcd touch display screen, loudspeaker and built-in application software.Shown by reference numeral is following: 1. RFID antenna; 2. RFID card reader; 3. WIFI unit; 4. WIFI antenna; 5. loudspeaker; 6. LCD backlight; 7.CPU; 8. 2.4G antenna, the Zigbee unit; 9. medicine is deposited the hurdle; 10. metal screen layer; 11. LCD display.
Fig. 5 reminds main user interface for the medication of intelligent medicine box, and font, background colour, word look all can independently be adjusted.The upper left corner shows the patient's name, directly over show the current date, the upper right side shows current time; The lower left shows doctor's name, contact method, doctor's advice.The center is the form of taking medicine the same day, branch time, medicine name, deal three hurdles.What smiling face's mark was arranged before the hurdle is to have taken medicine, and no smiling face's mark is not take medicine before the hurdle, and the high bright hurdle of black of the middle yellow end is the current need things of taking medicine.
Fig. 6 is the multi-core network framework (trunk portion) of intelligent medicine box.Accomplish nine big functions altogether, each function all is made up of separately dedicated cpu processor, converter and hardware cell, builds the multinode interconnect architecture jointly.
Fig. 7 is the three-decker of CDM material, i.e. " aluminium foil---epoxy adhesive---aluminium foil ".The left side is the preceding state of energising, and trilaminate material tightly sticks together, and the patient can't tear packing.The right side is the state behind energising Vd, the duration Vt, and aluminium foil can peel off from epoxy adhesive, and the patient can tear packing.
Fig. 8-9-10 is the structural drawing of intelligent drug packaging.Fig. 8 is that medicine is positive, and exposed printing antenna and RFID label are housed on the aluminium foil.Connected by microcircuit between the tablet, open convenient location, position the record.Shown by reference numeral is following: 1. tablet; 2. microcircuit; 3.RFID label; 4. printing antenna; 5. aluminium foil.Fig. 9 is the tablet reverse side, is made up of near field coil (perception start signal), chip for driving, MCU (processing open command), battery and direct current transducer.The tablet edge is connected on the direct current transducer by the CDM material package, only when output voltage is higher than 30V, just can open.Shown by reference numeral is following: 1. battery; 2. tablet encapsulation; 3.DC-DC converter; 4.MCU microprocessor; 5. aluminium foil; 6. chip for driving; 7. near field coil.Figure 10 is the hardware synoptic diagram.
Figure 11 is the hardware configuration synoptic diagram of intelligent label iTag, is made up of sensor, MCU, battery, RF transceiver.Sensor is worn on one's body the patient, is responsible for all kinds of health parameters of acquisition and recording, handles through MCU, is sent to intelligent medicine box by the RF transceiver again and stores.
Figure 12 is 2 generation RFID label hardware configuration synoptic diagram.EPC Gen2 RFID Tag uses for many high performance systems has very strong ductility.Compare with generation RFID label, in two generations, had a distinct increment at aspects such as data capability, transfer rate, information securities.Reading speed is near 4 times of a generation; Support repeatedly read-write; 4 read modules are arranged, make it and the parallel communication of a plurality of readers.At secure context, two generation label used the 32bit key.Aspect extendability, the user memory space very flexibly, and is little of 0-64bit, arrives 2048bit even more greatly.
Figure 13 is the another kind of process flow diagram of opening the method for intelligent packaging.Rfid interrogator promptly is housed in drug packaging, the RFID label is housed on medical card.Both near the time, read write line is with the ID on the reading tag number and compare with the key that is stored among the MCU, if meet, then allows to unpack.
Figure 14 is the SQL major key and generation form of electronics prescription.The electronics prescription comprises patient information, information about doctor, doctor's advice, medicine time table, medicine information etc., is generated automatically by hospital database, supplies the intelligent medicine box down loading updating.The prompting that intelligent medicine box is provided aspect taking medicine, record, feedback function are accomplished based on the electronics prescription fully.
Intelligent medicine box has the supporting magnetic card of a record patient personal information, has 2 generation RFID labels, and available infrared scan mode is landed intelligent medicine box.Behind the login system, will show on the intelligent medicine box main screen patient's name, current date, current time, current weather, doctor's name, doctor's advice and the same day medicine take table (according to the time descending sort).
The medicine time of every doctor's regulation, intelligent medicine box can remind the patient to take medicine with various multimedia meanses.When medicine was removed, rfid interrogator perception in time should be moved, and whether detection gets it filled correct, like the tablet start signal of correctly then sending correspondence position.Can pass through Interactive Button manual feedback information after the patient takes medicine, also can monitor automatically and feedback information through the miniature ring circuit in the drug packaging.In case faulty operation appears, as miss, obey more, abandon etc., also can be by timely record.
Be worn on patient intelligent label iTag on one's body and can assist monitoring body parameter (like cardiogram, blood pressure, the oxygen content of blood, breathing oxygen content, blood-sugar content, shell temperature etc.) etc.This label is equivalent to a sensor, can patient's daily behavior, body parameter be passed to intelligent medicine box through radio sensing network, is convenient to doctor's long-term observation and continuous recording PD trend.
In case emergency appears in the patient, like acute allergic reaction, miocardial infarction etc., intelligent medicine box monitors its sign parameter and has exceeded warning value, will give the alarm to first-aid centre the very first time.

Claims (8)

1. the intelligent medical service system based on RFID and CDM technology is characterized in that: comprise that sensing data acquisition layer, medical resource administration and supervision authorities and intelligent medical service provide layer; Wherein:
Said sensing data acquisition layer is made up of a plurality of modules such as data acquisition equipment, data counting device, data storage device, data transmission set and medicine opertaing devices; Wherein, data acquisition equipment comprises existing conventional medical data acquisition equipment, also comprises the read-write RFID label that is used to gather patient's MAR; Data counting device and Data Holding Equipment are responsible for that image data is carried out a series of science and are calculated, and extract, keep and integrate valid data, to improve terseness, the readability and professional of data; Data transmission set is a media with the multiple network technology, and the data after integrating are sent to the medical resource administration and supervision authorities;
Each module of said sensing data acquisition layer is done the as a whole inside that is integrated in intelligent medicine box; Become a kind of family intelligent terminal; It has combined RFID sensing technology, CDM material technology, supports various kinds of sensors network, wireless network, 3G/4G network; One end of intelligent terminal connects the upper strata public service platform, and the other end of intelligent terminal is realized private Self-Service, comprising: medication alert and record, intelligent drug packaging control, sign parameter acquisition record, emergency situations alarm, doctor's suggestion is long-range obtains;
Said intelligent medical service provides the net background of layer as intelligent medicine box, comprises hospital, first-aid centre, a plurality of medical mechanisms of medicine supply chain; These medical mechanisms have extensive and abundant software support as serving the provider, to guarantee to realize systemic-function; Wherein, hospital provides the service of sign parameter monitoring, prescription download service, healthy newspaper Push Service, the subscription services of seeking medical advice, remote diagnosis service; First-aid centre provides the service of first aid alarm monitoring; The medicine supply chain provides medicine true and false inquiry service, medicine explanation inquiry service; Service provider border factually needs to set, changes, expands service content, and the intelligent medicine box terminal can be accomplished service synchronization work automatically;
Said medical resource administration and supervision authorities provide the transition auxiliary layer of layer as sensing data acquisition layer and medical services, mainly are responsible for the unified monitoring and control of system, manage the distribution medical resource with the science mode, promote its operational paradigm; The specialty support that provides to each tame medical institutions has nothing in common with each other; The medical resource administration and supervision authorities need be discerned the information that the data acquisition layer is submitted, add up, screening, classification processing; And according to patient's different demands; Be sent to corresponding medical services provider, the information processing efficiency and the feedback efficiency of serving the provider with raising.
2. intelligent medical service system according to claim 1 is characterized in that: described intelligent medicine box is a rectangular parallelepiped chest, and supporting with it intelligent label and intelligent packaging;
1 shift knob, 2 RS232 interfaces, 1 USB interface, 1 SD socket, 1 sim card slot, 1 Ethernet interface, 1 infrared scanner and 1 tripod ac plug are housed on the intelligent medicine box casing;
Intelligent medicine box top cover inside is embedded with 1 10.1 inches touch LCD display screen, 1 boombox; The built-in 32bit XscaleCPU of medicine-chest, WAN adapter, UHF RFID antenna and reader, Zigbee monolithic converter, WIFI antenna, WIFI unit, lcd touch display screen, loudspeaker and corresponding application software; Medicine-chest supports GSM/GPRS communication to communicate by letter with 3G network;
Intelligent medicine box takes metal electric magnetic shielding mode that the strictness of RFID signal is strapped in box house, and simultaneously, the antenna of rfid interrogator is the U type and is uniformly distributed at the bottom of the case, makes it can evenly read the medicine RFID label signal of any position in the case.
3. intelligent medical service system according to claim 2 is characterized in that: the hardware structure of said intelligent medicine box is a kind of netted multicore architecture that is integrated on the chip, is made up of two parts, is respectively trunk system and from the part system; Wherein:
Said trunk system is that intelligent medicine box is supported nine big functions: audio frequency, video, WAN, WSN, instant ECG, examine in advance immediately, task management, RFID manage and other instant projects; Each function all has dedicated cpu processor, converter and hardware cell separately, builds the interconnect architecture of multinode jointly;
Saidly comprise intelligent sensing label and intelligent drug packaging two parts from the part system; Wherein, the intelligent sensing label is made up of sensor, microprocessor MCU, battery, radio frequency converter and antenna; The intelligence drug packaging is made up of CDM array, battery, DC-DC converter, energy harvester, FSM, radio frequency converter and antenna; Carry out radio communication from the part system through antenna and trunk system, accept the unified distribution management.
4. intelligent medical service system according to claim 3 is characterized in that: said intelligent medicine box has a supporting RFID magnetic card, is writing down user's personal information, and the user can be through the operation login medicine-chest system that swipes the card; Medicine-chest is after the ID that has read the patient number; Communicate through 3G network and server; The electronics prescription information that retrieval and downloading patient information, information about doctor, doctor provide from hospital's SQL database of correspondence, and store in the storer, keep regular update;
In the electronics prescription that the doctor provides, comprise following data: patient should take medicine article ID, the quantity of taking medicine and the time set table of taking medicine; When needs generate complete prescription and supply the patient to download; System will inquire about drug data bank automatically; According to title, model, coding, the specification information of medicine ID coupling medicine, and the data that these information and pharmaceutical production manufacturer provide are identical, like this after medicine is placed into intelligent medicine box; Medicine-chest just can carry out the data comparison, accurately identifies the medicine that the patient buys.
5. intelligent medical service system according to claim 4; It is characterized in that: after said intelligent medicine box is put into medicine; The distributed U type rfid interrogator antenna of bottom half refreshes mode through fixed frequency and reads the RFID label in the drug packaging; Note the medicine information that is pre-stored in wherein, and verify comparison with the electronics prescription that the doctor provides; When having medicine of the same race in the comparison result shows electronics prescription, intelligent medicine box can be accomplished a series of registrations, record, inquiry, analytical work on the backstage, realizes drug control intellectuality, robotization, systematization;
Simultaneously, intelligent medicine box can also communicate with the pharmaceutical production merchant, obtains the complete production procedure information of this medicine, thereby effectively discerns counterfeit drug, guarantees patient's personal safety;
After the intelligent medicine box completion is operated correspondence, affirmation, the typing of medicine and prescription, just change over to and carry out the medication alert function; At first, LCDs shows the detailed information of taking medicine; Bright color, succinct design are adopted in main interface, and the interface title block comprises three information, is respectively patient's name, date and time, sinks to the bottom the hurdle and comprises doctor's name, doctor's contact method and doctor's advice; The master meter lattice of interface center according to the time descending sort patient all medicines and the medication remarks that need take the same day, every kind of medicine occupies delegation, every row comprises three row, is respectively medicine name, medicine time and single and takes deal; Having taken medicine has smiling face's mark before capable, does not take medicine and does not mark, and the next item down waits to take medicine then with the bright capable form enlarged and displayed of height.
6. intelligent medical service system according to claim 5; It is characterized in that: said medicine adopts intelligent packaging; Be that drug packaging adopts CDM technology and RFID technological, intelligent medicine box can be controlled drug packaging, and detail record patient time, kind and the deal of taking medicine;
Said intelligent packaging; Constitute by CDM material, RFID label, rfid interrogator, near field coil, charge pump, direct current transducer, battery, medical card, microprinting circuit and selector switch; Can accept the RFID instruction control; Various drug taking behaviors to the patient detect automatically, record; Comprise open packing, clothes down medicine, forget and take medicine, damage medicine, abandon medicine, can also guarantee that the medicine time of medicine and deal all receive strict control, phenomenon that effective prevention is taken medicine in advance or excess is taken medicine;
In the intelligent packaging, the CDM material is aluminium foil, epoxy adhesive, aluminium foil three-decker, and two-layer up and down aluminium foil is connected to the voltage output end and the earth terminal of monitor respectively, and epoxy adhesive has superstrong adhesive, the tightly adhesion of whole trilaminate material;
A RFID label is arranged on the intelligent packaging, and the inside stores the details of medicine; Medicine is placed in the intelligent medicine box, and the rfid interrogator antenna at the bottom of the case reads this label repeatedly with fixed frequency, to confirm that medicine exists; This RFID label adopts CMOS integrated circuit and coil antenna, and way to take power is that antenna is placed in the electromagnetic field, and from the electromagnetic field of the same area, obtains major clock; Through opening and closing modulating current, chip will send it back ID number of 8 Manchester's cdes and be stored in the preprogrammed memory array;
Rfid interrogator is the integrated RFID transceiver circuit of CMOS; Rfid interrogator obtains to be suitable for the resonant frequency of antenna through inner phase-locked loop pll; It makes antenna be operated in carrier frequency, and aerial signal is carried out amplitude modulation synchronous modulation and demodulation, and realizes and microprocessor communication through interface;
The input voltage range of charge pump current mode pulse width modulated step-up DC-DC converter is from 2.5V to 10V, and adjustable output voltage is up to 30V;
Medical card is a big capacity, programmable two generation RFID labels, and before receiving the information of medical package, medical card is in off working state; When receive from rfid interrogator read signal the time, medical card is activated, and sends out ID number; If ID number meets, medical package sends another reading command to medical card, and medical card sends to packing with all medication information of patient subsequently; At last, when the information that stores in the packing changes with medical card near, to obtain the interior lastest imformation of packing;
Be printed on microprinting circuit and selector switch in the drug packaging; Selector switch makes medicine can gradation controlled, and the microprinting circuit is used to confirm the current state of medicine, and concrete mode is: when medicine did not take out as yet, the CDM material was perfect, and the microprinting circuit all is communicated with, and current signal exists; After certain medicine was removed, this regional CDM material was damaged, so microprinting circuit that should the zone also cuts off current vanishes thereupon; The current signal of disappearance marks amount of pills and the position that the patient had taken; And the transmit antenna feedback of passing through on the packing is given medicine-chest; As choose the reference of opening which pill next time, also feed back to the doctor simultaneously, the proof of on time taking medicine according to quantity as the patient.
7. intelligent medical service system according to claim 6; It is characterized in that: the patient wears the intelligent label iTag of specialty on one's body; Communicate by letter with intelligent medicine box with radio sensing network WSN; At any time monitor patient's daily behavior, body parameter, body parameter comprises cardiogram, blood pressure, the oxygen content of blood, breathing oxygen content, blood-sugar content, shell temperature; All heat transfer agents are regularly pushed to the Control Room of hospital, are monitored in real time by medical personnel; If the patient does not feel well, can press convenient pushbutton enable voice recognizer, say the subjective feeling of oneself and send to hospital to audio-frequency information, seek doctor's help.
8. intelligent medical service system according to claim 7; It is characterized in that: said intelligent medicine box is built-in with the reliable instant data processing algorithm through experimental demonstration; Can be according to collecting the sign health parameters; Examine in advance for the patient carries out the basis in the very first time, first place, provide reasonable suggestions, and valuable advisory opinion is provided for follow-up seeking medical advice; Intelligent medicine box is also integrated a series of violation operation records, body parameter Monitoring Data, patient's subjective feeling and is examined the result immediately in advance, is sent to public service platform, to obtain doctor specialty feedback and guidance timely; Simultaneously; Intelligent medicine box remains with the service platform of first-aid centre and communicates by letter; In case the intelligent label that the patient wears on one's body monitors emergency condition, intelligent medicine box can the very first time send the alarm of seeking help, or is controlled by patient oneself and to give the alarm; This alarm comprises patient position, state of an illness type information, assists first-aid centre to launch targetedly efficiently relief.
CN2012100665576A 2012-03-14 2012-03-14 Intelligent medical service system based on RFID (radio frequency identification devices) and CDM (code division multiplex) technologies Pending CN102609626A (en)

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