CN102600364B - Application of bletilla in preparation of medicine for allergic skin treatment, burnt wound restoration and tissue and skin regeneration promotion - Google Patents

Application of bletilla in preparation of medicine for allergic skin treatment, burnt wound restoration and tissue and skin regeneration promotion Download PDF

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CN102600364B
CN102600364B CN 201210068262 CN201210068262A CN102600364B CN 102600364 B CN102600364 B CN 102600364B CN 201210068262 CN201210068262 CN 201210068262 CN 201210068262 A CN201210068262 A CN 201210068262A CN 102600364 B CN102600364 B CN 102600364B
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tissue
wound
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CN102600364A (en
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沈慰平
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Abstract

The invention belongs to a new purpose of medicine, in particular to an application of bletilla to preparation of medicine for allergic skin treatment, burnt wound restoration and tissue and skin regeneration promotion. Burnt wound patients with the allergic skin accounts for 1 percent of the total burnt patients, the burnt wound of the allergic skin is a branch of the burnt wound, and the effective treatment medicine is lacked in the prior art, so the market potential is huge. The medicine provided by the invention and water extracts of the medicine can promote the tissue and skin regeneration. The extracts are effective substances for promoting the tissue and skin regeneration not discovered in the prior art.

Description

Pseudobulbus Bletillae (Rhizoma Bletillae) preparation treatment allergic skin burns repair in trauma and impels tissue and the application of skin regeneration medicine
Technical field:
The invention belongs to a kind of new purposes of medicine, particularly a kind for the treatment of allergic skin for preparing burns repair in trauma and impels tissue and the application of skin regeneration medicine.
Background technology:
Burn mainly refers to skin, mucosa, the even infringement of deep tissue that heating power, chemical substance, electric energy, lonizing radiation etc. cause.Wherein skin heat injury (as flame, boiled water etc.) is the most common.According to statistics, annual death toll because of unexpected injury, burn is only second to vehicle accident, comes second, and also has a large amount of wounded to merge burn in the vehicle accident injury.China's burn annual morbidity is about 1.5%~2%, namely approximately has every year 2000 ten thousand people to suffer to burn in various degree, and wherein approximately 5% burn patient needs hospitalization.The burn healthhazard had both comprised physiological, also comprised psychological.Burn can be classified according to mechanism, the degree of depth, degree and the related injury and complication of injury, distinguishes according to the degree of depth.At present, to the different degree of depth of skin, can roughly burn once be divided into two degree (shallow two degree, dark two degree), third degree burn according to burn injury.Superficial burn (once, shallow two degree) may or common drug can normal healing, the dark two above diagnoses and treatment for burn of degree are most important, deep second degree burn is because the damage skin corium therefore cause scar hyperplasia, usually needs surgical debridement and skin grafting.
The medicine that general therapeutic burns wound is a lot, but present medicine all can't resolve a kind of wound repair of burning wound of special population.Its main cause is allergic constitution skin for the patient of these special populations, after using at present commercially available treatment medicine commonly used, can cause wound surface to produce eczema, erosion, cause that wound surface further deepens necrosis, so that redness occurs and festers in normal skin around wound surface simultaneously, is difficult to cure.
Summary of the invention:
Goal of the invention:
The objective of the invention is provides a kind of curable substance allergic skin burn repair in trauma and impel tissue and the new purposes of skin regeneration for burning trauma patient for allergic skin.
Technical scheme:
Pseudobulbus Bletillae (Rhizoma Bletillae) preparation treatment allergic skin burns repair in trauma and impels tissue and the application of skin regeneration medicine;
Burn repair in trauma and impel tissue and the application of skin regeneration medicine as a kind of optimal way Pseudobulbus Bletillae (Rhizoma Bletillae) water extract preparation treatment allergic skin.
The preparation method of the water extraction of this medicine:
The Pseudobulbus Bletillae (Rhizoma Bletillae) is pulverized, sieve more than 80 orders, take 100 orders as good; Boiling water extraction is filtered or centrifugalize, and filtrate is concentrated makes extractum, gets final product finished product, and external application is changed dressings 1 every day.
The relevant every regulation of appendix unguentum of version in 2005 is prepared into externally used paste.
The Pseudobulbus Bletillae (Rhizoma Bletillae) (Bletilla striata (Thunb.ex A.Murray) Rchb.f.)
Characteristics of the present invention and effect:
1, the Pseudobulbus Bletillae (Rhizoma Bletillae) is as conventional Chinese medicine, and effect is astringing to arrest bleeding, detumescence and promoting granulation.Be used for hemoptysis and spit blood, traumatic hemorrhage, sore swollen toxin, chapped skin; The pulmonary tuberculosis hemoptysis, ulcer haemorrhage.It can treat burn and surgical wound, but the report that has no as the treatment allergic skin, the present invention has good curative effect according to its burning wound at allergic skin of long-term clinical discovery, the invention belongs to selection invention, and find that its water extract effect is obvious, enlarge the scope of application of the Pseudobulbus Bletillae (Rhizoma Bletillae), increased applicable disease.
2, the patient without allergic skin uses commercially available medicine, once, the burning wounds of shallow two degree, dark two degree, and healing that all can be progressively.But the allergic skin patient is because the commercially available burning wound medicine of self skin allergy reason use causes that on the contrary wound surface progressively increases the weight of, the local woanded surface redness is festered, so that the normal skin around wound surface festers, general malaise, insomnia, heating simultaneously, obstinate, the patient suffering can't bear, and can cause cicatrix, becomes the difficult problem of current burning wound circle.Through using the other drug obstinate and having the upward patient of symptom, use the present invention to make the patient of allergic skin burn wound and wound surface afterwards and do not produce eczema, redness, erosion, successfully wound repairing tissue and skin regeneration.
2, the burning trauma patient of allergic skin accounts for 1% of total burning trauma patient, and the burning wound of allergic skin is a branch of burning wound, and existing the needs lacks effective medicine, so market potential of the present invention is huge.
3, this invention and water extract thereof also can impel tissue and skin regeneration.This extract is there is no at present the found active substance that impels tissue and skin regeneration.
Description of drawings
Fig. 1 is photo before and after embodiment 2 treatments
Fig. 2 is for implementing the 2 rear photos for the treatment of
Fig. 3 is photo before embodiment 5 treatments
Fig. 4 is photo after embodiment 5 treatments.
The specific embodiment:
The present invention further illustrates as follows in conjunction with the embodiments:
Embodiment 1
The preparation method of the water extraction of this medicine:
The Pseudobulbus Bletillae (Rhizoma Bletillae) is pulverized, sieve more than 80 orders, take 100 orders as good; Boiling water extraction is filtered or centrifugalize, and filtrate is concentrated makes extractum, gets final product finished product, and external application is changed dressings 1 every day.
The medication of following examples is that embodiment 1 obtains finished product.
Embodiment 2
Turn round and look at the XX man, 46 years old, the Yancheng City civil servant, dark two degree of left hand and forearm are scalded, many hospitalizes after 7 days, wound surface festers, eczema on every side, and blood plasma oozes out many, limb swelling is obvious, wound surface companion fungal infection, in Jiangsu Prov. People's Hospital medical expert's consultation suggestion skin-grafting, and think that cicatrix and pigmentation are arranged on inspection; Be allergic skin through being diagnosed as this patient, through the treatment of 3 days treatment combination antibiotics of the present invention, swelling is all disappeared, and wound surface was repaired substantially in 10 days, and 26 days skin as before.Without any pigmentation and cicatrix.See accompanying drawing 1,2.
Embodiment 3
King XX, female, 57 years old, the teacher, face, left upper extremity accounts for bulk area 3% capsicum solution (police) spray wound, after festering, infection scalds for dark two degree, Yancheng City First People's Hospital dermatological treatment 10 days, because wound surface can't heal, facial swelling, blood plasma oozes out, and turns Yancheng City institute of traditional Chinese medicine department of dermatologry, treated 9 days, wound surface still can't heal, facial swelling, and blood plasma oozes out; Be allergic skin after diagnosing, through using the present invention's treatment, suitably use the antibiotic medicine, detumescence in 3 days, 10 days wound healings, 28 days skin as before, without any pigmentation and cicatrix.
Embodiment 4
Soup XX, the female, 19 years old, dark two degree of two lower limb were scalded, and Yancheng City First People's Hospital's Department of B urn treatment 40 days, because wound surface festers, blood plasma oozed out obviously, and limbs swell and ache, and can't fall asleep round the clock to have reached a week; Be allergic skin after diagnosing.Through using the present invention's treatment, suitably use the antibiotic medicine, fell asleep 6 hours after using the present invention the same day, detumescence in 3 days, 7 days wound healings, 27 days skin as before, without any pigmentation and cicatrix.
Embodiment 5
Week XX, the man, 55 years old, back and abdominal part warmer were scalded, and account for surface 5%, were dark 2 degree wound surface, and wound surface festers, and blood plasma oozes out obviously, and lower back swelling is allergic skin after diagnosing.Through using the present invention's treatment, suitably use the antibiotic medicine, detumescence in 3 days, 12 days wound healings, 26 days skin as before, without any pigmentation and cicatrix.See accompanying drawing 3,4.

Claims (2)

1. Pseudobulbus Bletillae (Rhizoma Bletillae) preparation treatment allergic skin burns repair in trauma and impels tissue and the application of skin regeneration medicine.
2. Pseudobulbus Bletillae (Rhizoma Bletillae) preparation treatment allergic skin according to claim 1 burns repair in trauma and impels tissue and the application of skin regeneration medicine, it is characterized in that the described Pseudobulbus Bletillae (Rhizoma Bletillae) is water extract.
CN 201210068262 2012-03-15 2012-03-15 Application of bletilla in preparation of medicine for allergic skin treatment, burnt wound restoration and tissue and skin regeneration promotion Active CN102600364B (en)

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CN103610061B (en) * 2013-12-03 2014-10-15 马军保 Health care product used by smokers
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CN1331517C (en) * 2005-07-06 2007-08-15 孙传红 Plaster contg. tuber of hyacinth bletilla for treating burns

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