CN102600229A - Method for improving content of levodopa of broad bean flower - Google Patents
Method for improving content of levodopa of broad bean flower Download PDFInfo
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- CN102600229A CN102600229A CN2012100771452A CN201210077145A CN102600229A CN 102600229 A CN102600229 A CN 102600229A CN 2012100771452 A CN2012100771452 A CN 2012100771452A CN 201210077145 A CN201210077145 A CN 201210077145A CN 102600229 A CN102600229 A CN 102600229A
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- levodopa
- viciae fabae
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- broad bean
- flower
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Abstract
The invention discloses a method for improving content of levodopa of a broad bean flower. The method for improving the content of the levodopa of the broad bean flower comprises the following steps of: firstly selecting a broad bean flower variety with the levodopa content being more than 11%; then picking up a complete broad bean flower when a flower bud is just bloomed into a flower; and finally placing the picked broad bean flower in drying equipment being 40-100 DEG C to be dried and dehydrated, wherein the best drying temperature is 35-50 DEG C. According to the invention, the technical scheme is adopted, and the drying equipment is used for carrying out low temperature drying and dehydration, and the loss of the content of the levodopa in the broad bean flower is reduced. Thus, the content of the levodopa contained in broad bean flower raw material is ensured to be high, can be more than 11% and is 2.2-3.7 times that of the existing velvet bean seed, thus a high-quality raw material variety is provided for levodopa plant extraction.
Description
Technical field
The present invention relates to a kind of method that improves levodopa content in the plant, relate in particular to a kind of method that improves Flos Viciae fabae levodopa content.
Background technology
Levodopa (molecular formula C
9H
11NO
4) promptly 3; 4-dihydroxy-phenylalanine; Be catecholamine hormones in the organism, neurotransmitter (like norepinephrine, dopamine) and melanic metabolic precursor thereof; Being mainly used in treatment Parkinsonism, hepatic coma, fracture, neuralgia etc., is the main medicine of treating parkinson disease (Parkinson s disease) at present.
At present the clinical used levodopa of China mainly relies on import, domestic also have from Herba chenopodii bean plant Herba chenopodii bean seed extract.Herba chenopodii bean seed contains levodopa 3-5%, and it is lower to extract yield, is the key factor that influences plant source levodopa output.
The plant variety of extracting levodopa at present is a Herba chenopodii bean seed, its levodopa content 3-5%, and it is low therefore to extract yield, and production cost is high, has restricted the output of plant source levodopa.
Summary of the invention
The object of the invention provides the method that a kind of Flos Viciae fabae levodopa content reaches the raising Flos Viciae fabae levodopa content more than 11%.
The present invention adopts following technical scheme: the method that Flos Viciae fabae levodopa content improves is following:
A. screening varieties: choose Flos Viciae fabae levodopa content greater than 11% Semen Viciae fabae kind;
B. pluck: the plantation Semen Viciae fabae, at Semen Viciae fabae florescence in time gather the alabastrum that a bud just ready to burst or the flower when just open;
C. oven dry: Flos Viciae fabae is plucked drying and dewatering in the drying plant that is placed on 40-100 ℃ of temperature.
Among the described step C, the optimum temperature of Flos Viciae fabae oven dry is 35-50 ℃.
Among the described step C, the inferior Jia Wendu of Flos Viciae fabae oven dry is 50-65 ℃.
The present invention adopts above technical scheme, from the high Semen Viciae fabae kind of kind screening levodopa content; Before the Semen Viciae fabae flowering, pluck the alabastrum that a bud just ready to burst or the flower when just open, levodopa content begins to reduce behind the Semen Viciae fabae flowering, and the open hour are of a specified duration more, and levodopa content is low more.Pluck alabastrum or the flower when just open is in order to ensure containing higher levodopa in the Flos Viciae fabae raw material; Utilize the dehydration of drying plant oven drying at low temperature, reduce the loss of Flos Viciae fabae levodopa content in dehydration.Thereby improving Flos Viciae fabae levodopa content, can reach more than 11%, is 2.2-3.7 times of existing Herba chenopodii bean seed content, for the levodopa plant extract provides the high-quality raw material kind.
The specific embodiment
The method that Flos Viciae fabae levodopa content of the present invention improves is following:
A. screening varieties: from different Semen Viciae fabae kinds, choose Flos Viciae fabae levodopa content greater than 11% Semen Viciae fabae kind, the specific breed that extracts as the Flos Viciae fabae levodopa;
B. pluck: the plantation Semen Viciae fabae is to blooming, at Semen Viciae fabae florescence in time gather the alabastrum that a bud just ready to burst or the flower when just open.Flos Viciae fabae best opportunity of gathering is when alabastrum to flower is just open, to gather;
C. oven dry: Flos Viciae fabae is plucked drying and dewatering in the drying plant that is placed on 40-100 ℃ of temperature.
Among the described step C, the optimum temperature of Flos Viciae fabae oven dry is 35-50 ℃.
Among the described step C, the inferior Jia Wendu of Flos Viciae fabae oven dry is 50-65 ℃.
There is considerable influence in the levodopa content of different bake out temperatures after to the Flos Viciae fabae oven dry, and bake out temperature is high more, in the Flos Viciae fabae levodopa loss big more, content is just low more.Drying and dewatering test according to Flos Viciae fabae shows that when bake out temperature was the 40 degree left and right sides, levodopa content did not almost lose in the Flos Viciae fabae after the oven dry; When bake out temperature is the 60 degree left and right sides; Levodopa content loss 9-12% in the Flos Viciae fabae after the oven dry, when bake out temperature is the 80 degree left and right sides, the Flos Viciae fabae levodopa content loss 40-50% after the oven dry; When bake out temperature is 100 when spending, the Flos Viciae fabae levodopa content loss 54-62% after the oven dry.
Claims (3)
1. method that improves Flos Viciae fabae levodopa content is characterized in that: the method that this Flos Viciae fabae levodopa content improves is following:
A. screening varieties: choose Flos Viciae fabae levodopa content greater than 11% Semen Viciae fabae kind;
B. pluck: the plantation Semen Viciae fabae, at Semen Viciae fabae florescence in time gather the alabastrum that a bud just ready to burst or the flower when just open;
C. oven dry: Flos Viciae fabae is plucked drying and dewatering in the drying plant that is placed on 40-100 ℃ of temperature.
2. the method for raising Flos Viciae fabae levodopa content according to claim 1 is characterized in that: among the described step C, the optimum temperature of Flos Viciae fabae oven dry is 35-50 ℃.
3. the method for raising Flos Viciae fabae levodopa content according to claim 1 is characterized in that: among the described step C, the inferior Jia Wendu of Flos Viciae fabae oven dry is 50-65 ℃.
Priority Applications (1)
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CN2012100771452A CN102600229A (en) | 2012-03-22 | 2012-03-22 | Method for improving content of levodopa of broad bean flower |
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CN2012100771452A CN102600229A (en) | 2012-03-22 | 2012-03-22 | Method for improving content of levodopa of broad bean flower |
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CN2012100771452A Pending CN102600229A (en) | 2012-03-22 | 2012-03-22 | Method for improving content of levodopa of broad bean flower |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104186288A (en) * | 2014-08-13 | 2014-12-10 | 福建省农业科学院作物研究所 | LED light source cultivation method for improving levodopa content of broad bean sprouts |
CN104489668A (en) * | 2014-12-12 | 2015-04-08 | 重庆市农业科学院 | Method for preparing rapidly rehydrated broad bean flowers |
CN109043044A (en) * | 2018-08-29 | 2018-12-21 | 成都市农林科学院 | A kind of broad bean sprouting vegetable tea bag and preparation method thereof of richness levodopa |
CN109081787A (en) * | 2018-09-28 | 2018-12-25 | 那坡康正天然植物提取有限责任公司 | A kind of technique for extracting levodopa from multitude's beans |
CN109096131A (en) * | 2018-09-28 | 2018-12-28 | 那坡康正天然植物提取有限责任公司 | A kind of technique preparing levodopa using cat beans |
-
2012
- 2012-03-22 CN CN2012100771452A patent/CN102600229A/en active Pending
Non-Patent Citations (1)
Title |
---|
曹奕鸯: "蚕豆左旋多巴(L-DOPA)含量的研究", 《福建农林大学硕士学位论文》 * |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104186288A (en) * | 2014-08-13 | 2014-12-10 | 福建省农业科学院作物研究所 | LED light source cultivation method for improving levodopa content of broad bean sprouts |
CN104186288B (en) * | 2014-08-13 | 2015-12-02 | 福建省农业科学院作物研究所 | A kind of LED light source cultivation method improving broad bean shoot vegetable levodopa content |
CN104489668A (en) * | 2014-12-12 | 2015-04-08 | 重庆市农业科学院 | Method for preparing rapidly rehydrated broad bean flowers |
CN104489668B (en) * | 2014-12-12 | 2016-06-29 | 重庆市农业科学院 | A kind of preparation method of fast rehydrating Flos Viciae fabae |
CN109043044A (en) * | 2018-08-29 | 2018-12-21 | 成都市农林科学院 | A kind of broad bean sprouting vegetable tea bag and preparation method thereof of richness levodopa |
CN109081787A (en) * | 2018-09-28 | 2018-12-25 | 那坡康正天然植物提取有限责任公司 | A kind of technique for extracting levodopa from multitude's beans |
CN109096131A (en) * | 2018-09-28 | 2018-12-28 | 那坡康正天然植物提取有限责任公司 | A kind of technique preparing levodopa using cat beans |
CN109096131B (en) * | 2018-09-28 | 2021-01-15 | 那坡康正天然植物提取有限责任公司 | Process for preparing levodopa by utilizing velvet beans |
CN109081787B (en) * | 2018-09-28 | 2021-01-15 | 那坡康正天然植物提取有限责任公司 | Process for extracting levodopa from mucuna |
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Application publication date: 20120725 |