CN102600049A - Medical unhairing spray and purpose of medical unhairing spray - Google Patents

Medical unhairing spray and purpose of medical unhairing spray Download PDF

Info

Publication number
CN102600049A
CN102600049A CN2012100769541A CN201210076954A CN102600049A CN 102600049 A CN102600049 A CN 102600049A CN 2012100769541 A CN2012100769541 A CN 2012100769541A CN 201210076954 A CN201210076954 A CN 201210076954A CN 102600049 A CN102600049 A CN 102600049A
Authority
CN
China
Prior art keywords
phase
spray
depilation
medical
mutually
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN2012100769541A
Other languages
Chinese (zh)
Other versions
CN102600049B (en
Inventor
徐克之
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing Yafang Pharmaceutical Co ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201210076954.1A priority Critical patent/CN102600049B/en
Publication of CN102600049A publication Critical patent/CN102600049A/en
Application granted granted Critical
Publication of CN102600049B publication Critical patent/CN102600049B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a medical unhairing spray. Through the medical unhairing spray provided by the invention, the existing and traditional skin preservation technology and products can be replaced, the unconventional traditional skin preservation can be fast, efficiently, safely and conveniently carried on operation receivers, the sterilization and the skin preservation succeed in one step, the infection rate of the skin preservation parts and the operation cuts is greatly reduced, and meanwhile, the operation risk is also reduced.

Description

Medical depilation spray and uses thereof
Technical field:
The present invention relates to medical depilation spray, belong to medicine, medical instruments field.
Background technology:
Preserved skin is exactly that skin to operative region carries out that chaeta is removed, cleaning, sterilization, carries out and reduce postoperative infection smoothly to guarantee operation.(understand contamination of incision, cause postoperative infection because of a large amount of antibacterials in skin, the hair, hair is not removed also can cause otch internal memory foreign body, cause infection of incisional wound, disunion).The preserved skin method can be divided into conventional traditional preserved skin and unconventional traditional preserved skin, and at present, what China adopted is conventional traditional razor preserved skin method, and its shortcoming is a lot, but because of no preserved skin substitute technology and product, so use till today always.
Figure BSA00000688252900011
Figure BSA00000688252900012
The shortcoming of conventional traditional preserved skin method:
1, the razor preserved skin can cause the skin histology damage; Skin histology visible trickle wound, hyperemia, ooze out, redness, patient's pain is felt bad, but also can cause the infection of preserved skin position and operative incision; The infection rate of conventional traditional preserved skin is 5.6%, has increased the risk of operation greatly.
2, razor preserved skin complicated operation, time-consuming, take a lot of work, require great effort, particularly the skinfold place has destroyed skin barrier, skin injury, the wound infection rate is high; Department of obstetrics and gynecology, urology department, oxter preserved skin are operated difficult.
" Guideline For Prevention of Surgical Wound Infections " (prevention of surgical wound infection guide) and U.S. peri-operation period registered nurse association (AORN) research report according to the Center for Disease Control CDC; Using the infection rate of the SSI of razor preserved skin is 5.6%; And use the SSI infection rate of depilatory preserved skin to be merely 0.6%; So; Dispoable medical depilation spray preserved skin can reduce the infection rate of operative site greatly, also is unique method and the approach that reduces NIR.
Summary of the invention:
One aspect of the present invention relates to a kind of medical depilation spray, it is characterized in that containing following components by weight ratio:
1. medical depilation spray is characterized in that containing following components by weight ratio: (%) prescription: (%)
A phase (oil phase) B phase (water)
High viscosity white oil 2.0-5.0 carbamide 5.0-10.0
Silicone oil 1.0-4.0 sodium pyrosulfite 0.2-0.4
Emulsifying agent 4.0-8.0 60% potassium hydroxide solution 3.0-7.0
16-18 alcohol 4.0-8.0 carbomer Carbopol 934 0.1-0.3
Stearic acid 1.0-3.0 glycerol 3.0-7.0
Essence 0-0.4 propylene glycol 3.0-7.0
Methyl p-hydroxybenzoate 0.1-0.3 deionized water adds to 100
Ethyl hydroxybenzoate 0.5-1.0
C phase (chemical agent phase) D phase (biological agent phase)
Three hydration calcium mercaptoacetate 6.0-15.0 triclosan or quaternary ammonium salt 0.1-3
Calcium hydroxide 0.8-1.5 neutral red bisabolol 0.2-0.4
E phase (plant extract phase/skin protection phase)
Mentholum 0.1-0.3
Vitamin E 0.5-1.5
Aloe extraction solution 3.0-7.0
F phase (propellant)
Normal butane, iso-butane and/or n-propane 7-10 or Compressed Gas (nitrogen) 10-30 or dimethyl ether 20-25 or fluoric ether 7-15
In a preferred implementation of the present invention, described emulsifying agent is A25.
In a preferred implementation of the present invention, described depilatory agent is three hydration calcium mercaptoacetates.
In a preferred implementation of the present invention, described propellant is normal butane, iso-butane and/or n-propane 7-10 or Compressed Gas (nitrogen) 10-30 or dimethyl ether 20-25 or fluoric ether 7-15.
In a preferred implementation of the present invention, antibacterial is triclosan and quaternary ammonium salt derivative, complex (polyquaternary ammonium salt, organosilicon quaternary ammonium salt, bi-quaternary ammonium salt polysiloxanes 0.1% one 3%).
In a preferred implementation of the present invention, anti-sensitizer is neutral red bisabolol 0.2%-0.4%.
In a preferred implementation of the present invention, described medical depilation spray is characterized in that containing following components by weight ratio: (%)
A phase (oil phase) B phase (water)
High viscosity white oil 2.0-5.0 carbamide 5.0-10.0
Silicone oil 1.0-4.0 sodium pyrosulfite 0.2-0.4
Emulsifying agent 4.0-8.0 60% potassium hydroxide solution 3.0-7.0
16-18 alcohol 4.0-8.0 carbomer Carbopol 934 0.1-0.3
Stearic acid 1.0-3.0 glycerol 3.0-7.0
Essence 0-0.4 propylene glycol 3.0-7.0
Methyl p-hydroxybenzoate 0.1-0.3 deionized water adds to 100
Ethyl hydroxybenzoate 0.5-1.0
C phase (chemical agent phase) D phase (biological agent phase)
Three hydration calcium mercaptoacetate 6.0-15.0 triclosan or quaternary ammonium salt 0.1-3
Calcium hydroxide 0.8-1.5 neutral red bisabolol 0.2-0.4
E phase (plant extract phase/skin protection phase)
Mentholum 0.1-0.3
Vitamin E 0.5-1.5
Aloe extraction solution 3.0-7.0
F phase (propellant)
Normal butane, iso-butane and/or n-propane 7-10 or Compressed Gas (nitrogen) 10-30 or dimethyl ether 20-25 or fluoric ether 7-15
The method for preparing of depilation spray of the present invention, comprise the steps: A phase (oil phase) and B mutually (water) be heated to respectively more than 80 ℃, then B phase (water) is slowly added in the A phase (oil phase), stir, homogenizing; Add C phase (chemicals phase), D phase (medicine phase), E phase (plant extract phase/skin protection phase) successively; Quantitative filling is to aluminium pot, and evacuation charges into F phase (propellant), sealing.
The present invention also relates to a kind of disposable depilation spray suit on the other hand, and it comprises the above-mentioned medical depilation spray of 25ml-100ml, disposable glove, a pasteurization towelette.
The invention still further relates to the application of above-mentioned medical depilation spray in operation preserved skin (depilation, antibacterial).
The present invention can replace existing traditional preserved skin technology and product; It can be fast, effectively, safety, quickly the patient is carried out unconventional traditional preserved skin; Sterilization, preserved skin be success once, greatly reduces the infection rate of preserved skin position and operative incision, has also reduced the risk of operation simultaneously.
The specific embodiment:
Prescription: (%)
A phase (oil phase) B phase (water)
High viscosity white oil 2.0-5.0 carbamide 5.0-10.0
Silicone oil 1.0-4.0 sodium pyrosulfite 0.2-0.4
Emulsifying agent 4.0-8.0 60% potassium hydroxide solution 3.0-7.0
16-18 alcohol 4.0-8.0 carbomer Carbopol 934 0.1-0.3
Stearic acid 1.0-3.0 glycerol 3.0-7.0
Essence 0-0.4 propylene glycol 3.0-7.0
Methyl p-hydroxybenzoate 0.1-0.3 deionized water adds to 100
Ethyl hydroxybenzoate 0.5-1.0
C phase (chemical agent phase) D phase (biological agent phase)
Three hydration calcium mercaptoacetate 6.0-15.0 triclosan or quaternary ammonium salt 0.1-3
Calcium hydroxide 0.8-1.5 neutral red bisabolol 0.2-0.4
E phase (plant extract phase/skin protection phase)
Mentholum 0.1-0.3
Vitamin E 0.5-1.5
Aloe extraction solution 3.0-7.0
F phase (propellant)
Normal butane, iso-butane and/or n-propane 7-10 or Compressed Gas (nitrogen) 10-30 or dimethyl ether 20-25 or fluoric ether 7-15
Compound method: 1, A phase (oil phase) and B mutually (water) respectively be heated to 85 ℃, then B phase (water) is slowly added in the A phase (oil phase), stir, homogenizing;
2, add C phase (chemicals phase), D phase (medicine phase), E phase (plant extract phase/skin protection phase) successively;
3, quantitative filling is to aluminium pot, and evacuation charges into F phase (gas phase), sealing.
The unit of each composition is G, can be KG also, is the content of percentage ratio.Wherein A-F is mutually The order and the purpose classification that add successively
Research group use Dispoable medical depilation spray preserved skin, routine shave mao preserved skin respectively (every group of 50 rats) 100 rats have been carried out the experiment of animal preserved skin pain stimulation, preserved skin depilation experiment, preserved skin depilation hair growth experiment after ten days; Preserved skin depilation position is the back; Dispoable medical depilation spray using dosage is 8g, preserved skin area 5cm 2, be 8 minutes action time, experimentation is found:
Research group use Dispoable medical depilation spray preserved skin, routine shave mao preserved skin respectively (every group of 50 rats) 100 rats have been carried out the experiment of animal preserved skin pain stimulation, preserved skin depilation experiment, preserved skin depilation hair growth experiment after ten days; Preserved skin depilation position is the back; Dispoable medical depilation spray using dosage is 8g, preserved skin area 5cm 2, be 8 minutes action time, experimentation is found:
Adopt medical depilation spray of the present invention, the preserved skin position does not have pain, and the preserved skin position is thoroughly clean, does not stay the dead angle, does not seal hair follicle, only rupture hair, depilation back has no adverse effects to the hair follicle root of hair, and the depilation group grows new hair again after ten days, and physiological function is normal.
Figure BSA00000688252900072
Should be understood that; The above-mentioned specific embodiment only is the exemplary explanation, rather than limitation of the present invention, concerning those of ordinary skills; Can improve or conversion according to above-mentioned explanation, and all these improvement and conversion all should belong to the protection domain of accompanying claims of the present invention.

Claims (6)

1. medical depilation spray is characterized in that containing the composition of following weight volume ratio (g/mL):
A phase B phase
High viscosity white oil 2.0-5.0 carbamide 5.0-10.0
Silicone oil 1.0-4.0 sodium pyrosulfite 0.2-0.4
Emulsifying agent 4.0-8.0 60% potassium hydroxide solution 3.0-7.0
16-18 alcohol 4.0-8.0 carbomer Carbopol 934 0.1-0.3
Stearic acid 1.0-3.0 glycerol 3.0-7.0
Essence 0-0.4 propylene glycol 3.0-7.0
Methyl p-hydroxybenzoate 0.1-0.3 deionized water adds to 100
Ethyl hydroxybenzoate 0.5-1.0
C phase D phase
Three hydration calcium mercaptoacetate 6.0-15.0 triclosan or quaternary ammonium salt 0.1-3
Calcium hydroxide 0.8-1.5 neutral red bisabolol 0.2-0.4
The E phase
Mentholum 0.1-0.3
Vitamin E 0.5-1.5
Aloe extraction solution 3.0-7.0
The F phase
Normal butane, iso-butane and/or n-propane 7-10 or compressed nitrogen 10-30 or dimethyl ether 20-25 or fluoric ether 7-15.
2. medical depilation spray is characterized in that containing the composition of following weight volume ratio:
A phase B phase
High viscosity white oil 2.0-5.0 carbamide 5.0-10.0
Silicone oil 1.0-4.0 sodium pyrosulfite 0.2-0.4
Emulsifying agent 4.0-8.0 60% potassium hydroxide solution 3.0-7.0
16-18 alcohol 4.0-8.0 carbomer Carbopol 934 0.1-0.3
Stearic acid 1.0-3.0 glycerol 3.0-7.0
Essence 0-0.4 propylene glycol 3.0-7.0
Methyl p-hydroxybenzoate 0.1-0.3 deionized water adds to 100
Ethyl hydroxybenzoate 0.5-1.0
C phase D phase
Three hydration calcium mercaptoacetate 6.0-15.0 triclosan or quaternary ammonium salt 0.1-3
Calcium hydroxide 0.8-1.5 neutral red bisabolol 0.2-0.4
The E phase
Mentholum 0.1-0.3
Vitamin E 0.5-1.5
Aloe extraction solution 3.0-7.0
The F phase
Normal butane, iso-butane and/or n-propane 7-10 or compressed nitrogen 10-30 or dimethyl ether 20-25 or fluoric ether 7-15.
3. medical depilation spray according to claim 1 and 2 is characterized in that described emulsifying agent is A25.
4. Dispoable medical depilation spray suit, it comprises any described medical depilation spray of 25ml-100ml claim 1-3, disposable glove, a pasteurization towelette.
5. the application of any described medical depilation spray of claim 1-3 in the operation preserved skin.
6. the method for preparing of claim 1 or 2 described depilation sprays comprises the steps: that A is heated to respectively more than 80 ℃ with B mutually mutually, then with B slowly add mutually A mutually in, stirring, homogenizing; Add C phase, D phase, E phase successively; Quantitative filling is to aluminium pot, and evacuation charges into the F phase, sealing.
CN201210076954.1A 2012-03-22 2012-03-22 Medical unhairing spray and purpose of medical unhairing spray Expired - Fee Related CN102600049B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201210076954.1A CN102600049B (en) 2012-03-22 2012-03-22 Medical unhairing spray and purpose of medical unhairing spray

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201210076954.1A CN102600049B (en) 2012-03-22 2012-03-22 Medical unhairing spray and purpose of medical unhairing spray

Publications (2)

Publication Number Publication Date
CN102600049A true CN102600049A (en) 2012-07-25
CN102600049B CN102600049B (en) 2014-03-19

Family

ID=46518080

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201210076954.1A Expired - Fee Related CN102600049B (en) 2012-03-22 2012-03-22 Medical unhairing spray and purpose of medical unhairing spray

Country Status (1)

Country Link
CN (1) CN102600049B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988236A (en) * 2012-11-30 2013-03-27 哈尔滨医科大学 Skin preparation solution used when head skin is prepared before neurosurgery operation and preparation method and application thereof
RU2657520C2 (en) * 2016-11-07 2018-06-14 Павел Александрович Громенко Cosmetic composition for removal of undesirable hair on the body of a person
CN114767563A (en) * 2022-05-09 2022-07-22 广州睿新生物科技有限公司 Mild and mild quick-acting depilatory composition and application thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1968676A (en) * 2004-06-15 2007-05-23 雷克特本克斯尔(英国)有限公司 Improvements in or relating to depilatory compositions
CN101756816A (en) * 2008-11-12 2010-06-30 曲磊 Calcium thioglycollate hair removal foam
CN102058488A (en) * 2010-11-11 2011-05-18 广州市好迪化妆品有限公司 Low-pressure type propellant and application thereof
WO2011103233A1 (en) * 2010-02-17 2011-08-25 The Procter & Gamble Company Effective depilatory article
CN102166169A (en) * 2010-11-29 2011-08-31 吴克 Follicle shrinking and unhairing cream
CN102281921A (en) * 2009-01-15 2011-12-14 雷克特和科尔曼(海外)有限公司 Topical composition

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1968676A (en) * 2004-06-15 2007-05-23 雷克特本克斯尔(英国)有限公司 Improvements in or relating to depilatory compositions
CN101756816A (en) * 2008-11-12 2010-06-30 曲磊 Calcium thioglycollate hair removal foam
CN102281921A (en) * 2009-01-15 2011-12-14 雷克特和科尔曼(海外)有限公司 Topical composition
WO2011103233A1 (en) * 2010-02-17 2011-08-25 The Procter & Gamble Company Effective depilatory article
CN102058488A (en) * 2010-11-11 2011-05-18 广州市好迪化妆品有限公司 Low-pressure type propellant and application thereof
CN102166169A (en) * 2010-11-29 2011-08-31 吴克 Follicle shrinking and unhairing cream

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988236A (en) * 2012-11-30 2013-03-27 哈尔滨医科大学 Skin preparation solution used when head skin is prepared before neurosurgery operation and preparation method and application thereof
CN102988236B (en) * 2012-11-30 2015-06-24 哈尔滨医科大学 Skin preparation solution used when head skin is prepared before neurosurgery operation and preparation method and application thereof
RU2657520C2 (en) * 2016-11-07 2018-06-14 Павел Александрович Громенко Cosmetic composition for removal of undesirable hair on the body of a person
CN114767563A (en) * 2022-05-09 2022-07-22 广州睿新生物科技有限公司 Mild and mild quick-acting depilatory composition and application thereof

Also Published As

Publication number Publication date
CN102600049B (en) 2014-03-19

Similar Documents

Publication Publication Date Title
TWI407906B (en) Disinfectant
JP4418976B2 (en) Antiseptic disinfectant and cosmetic composition
CN104105472A (en) Topical oil composition for the treatment of fungal infections
CN104490630A (en) No-washing foam hand disinfection solution and preparation method thereof
CN104188849A (en) Mild and effective acne removing and oil control composition and preparation method thereof
WO2014131191A1 (en) A composition containing honokiol and/or magnolol and uses thereof
CN102600049B (en) Medical unhairing spray and purpose of medical unhairing spray
CN102920612A (en) Broad-spectrum antibacterial cosmetic antiseptic and application thereof
CN111228201A (en) Preparation method of hand-washing-free gel
CN118103037A (en) High concentration molecular iodine composition, pharmaceutical preparation, preparation and use
CN107519236A (en) A kind of topical agent for treating onychomycosis
JP2008510805A (en) Cosmetic composition comprising certain cyclohexane mono-, di- or triol, or cyclohexylmethane, ethane or propanol
Miller et al. Local treatment of tinea capitis
CN105899221A (en) Dermatological composition based on algae and olive leaf extracts
CN109276485B (en) Acne removing patch and preparation method thereof
CN108451799A (en) A kind of hand cleanser and preparation method thereof
CN104815096A (en) Nano composite skin disinfection emulsion and preparation method of same
JP4113614B2 (en) Gel-like product manufacturing method
WO2019115503A1 (en) Propanediol monoacetate mononitrate
EP3166582A1 (en) Use of spiculisporic acid and/or a salt thereof as antidandruff agent, and cosmetic treatment process employing same
WO2014190227A1 (en) Wound care product with egg shell membrane
JPWO2014045961A1 (en) Dermatomycosis treatment
JP5138299B2 (en) Dermal preparation
CN104083406B (en) A kind of compound disinfectant and preparation method thereof
CN107412337A (en) A kind of hyaluronic acid sterilization conception control gel and preparation method

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20160408

Address after: 211505 D7 building, Zhongshan Science Park, Liuhe District, Jiangsu, Nanjing

Patentee after: NANJING YAFANG PHARMACEUTICAL Co.,Ltd.

Address before: 210061, No. 3-3, salt transportation road, Yi Town, Guanyun County, Jiangsu

Patentee before: Xu Kezhi

DD01 Delivery of document by public notice

Addressee: Xu Kezhi

Document name: payment instructions

DD01 Delivery of document by public notice
DD01 Delivery of document by public notice

Addressee: Xu Kezhi

Document name: Notice of Termination of Patent Rights

DD01 Delivery of document by public notice
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140319

CF01 Termination of patent right due to non-payment of annual fee