CN102579909B - 一种治疗慢性乙型肝炎的药剂 - Google Patents

一种治疗慢性乙型肝炎的药剂 Download PDF

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CN102579909B
CN102579909B CN 201210076981 CN201210076981A CN102579909B CN 102579909 B CN102579909 B CN 102579909B CN 201210076981 CN201210076981 CN 201210076981 CN 201210076981 A CN201210076981 A CN 201210076981A CN 102579909 B CN102579909 B CN 102579909B
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chronic hepatitis
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CN102579909A (zh
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胡爱民
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Hebei Wumo Biotechnology Co.,Ltd.
Wuhan Jing'e Tongpu Hospital Co ltd
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Abstract

本发明涉及一种治疗慢性乙型肝炎的药剂，它是由下列原料药制成的：半枝莲、焦三仙、党参、泽泻、酸枣仁、板蓝根、桔梗、黄芪、当归、茵陈、金钱草、淫羊藿。本发明所述的药剂以纯中药配制，采用传统的制作方法，保留了药物的药性，疗效明确，可有效地治疗慢性乙型肝炎。

Description

一种治疗慢性乙型肝炎的药剂
技术领域
本发明涉及医药领域，具体地说，涉及一种治疗慢性乙型肝炎的药剂。
背景技术
乙肝病毒检测为阳性，病程超过半年或发病日期不明确而临床有慢性肝炎表现者均可诊断为慢性乙肝。临床表现为：乏力、畏食、恶心、腹胀、肝区疼痛等症状。肝大，质地呈中度硬度，有轻压痛。病情较重者可伴有慢性肝病面容、蜘蛛痣、肝掌、脾大，肝功能可时有异常或持续异常。目前慢性乙型肝炎且呈逐年上升的趋势，因此需要治疗慢性乙型肝炎的药物。
发明内容
本发明的目的是提供一种治疗慢性乙型肝炎的药剂。
为了实现本发明的目的，本发明提供一种治疗慢性乙型肝炎的药剂，它是由下列原料药按重量份计制成的：
优选地，它是由下列原料药按重量份计制成的：
Figure BSA00000688283900012
优选地，所述药剂为片剂、分散片、胶囊剂、汤剂或软胶囊。
本发明所述的药剂以纯中药配制，采用传统的制作方法，保留了药物的药性，疗效明确，可有效地治疗慢性乙型肝炎。
具体实施方式
以下通过具体实施方式的描述对本发明作进一步说明，但这并非是对本发明的限制，本领域技术人员根据本发明的基本思想，可以做出各种修改或改进，但是只要不脱离本发明的基本思想，均在本发明的范围之内。
实施例1本发明汤剂的制备
取半枝莲100克、焦三仙100克、党参30克、泽泻30克、酸枣仁100克、板蓝根50克、桔梗50克、黄芪100克、当归50克、茵陈50克、金钱草100克、淫羊藿100克，置于2000毫升水中，在100℃下加热回流2小时，过滤，得到滤渣和滤液。将所述滤液浓缩至500毫升，即得。实验例
纳入标准
①符合2000年《乙型肝炎基础与临床》(骆抗先.乙型肝炎基础与临床[M].3版.北京：人民卫生出版社，2005：245-246.)中CHB的诊断标准。②HBsAg(+)、HBeAg(+)、HBV-DNA＞105cps·/mL。③ALT是正常值的2倍。④本次治疗前1个月内未使用其他抗病毒药物。
排除标准
①排除合并甲型肝炎、丙型肝炎、丁型肝炎、戊型肝炎者；②排除合并有酒精性肝病、自身免疫性肝病等其他肝病者；③排除疑似肝癌者；④排除在本次治疗前6个月内接受干扰素、免疫调节剂治疗者。
选取符合上述标准的患者50例，其中男性25例，女性25例。年龄18-48岁，平均33.5岁，病程3月-6年.
治疗方案
使用实施例1中制备的汤剂。每天服用2次，每次20毫升。半年为1个疗程。
疗效标准
参照《病毒性肝炎防治方案》(刘玉红，刘凤斌逍遥散加味联合甘利欣治疗慢性乙型肝炎生存质量观察[J].现代医院，2010，10(10)：21-23.)拟定疗效评定标准。显效：临床症状明显改善或消失，ALT及总胆红素(TBiL)降至正常水平，血清HBV-DNA转阴，HBeAg/抗-HBe血清转换。有效：临床症状明显好转，HBV-DNA转阴，HBeAg/抗-HBe血清未转换，ALT及总胆红素(TBiL)降至正常。无效：临床症状无明显改善，甚至病情加重。
治疗的结果：
经过治疗后发现所有患者均符合显效的标准。并且治疗过程中未观察到明显的不良反应。

Claims (2)

1.一种治疗慢性乙型肝炎的药剂，其特征在于，它是由下列原料药按重量份计制成的：
Figure FSB00001034661300011
2.根据权利要求1所述的治疗慢性乙型肝炎的药剂，其特征在于，它是由下列原料药按重量份计制成的：
Figure FSB00001034661300012
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1203804A (zh) * 1998-05-04 1999-01-06 刘煌清 肝病康复全方药
CN1253830A (zh) * 1999-12-06 2000-05-24 黄培乐 治疗肝炎、胆管炎、胰腺炎、肝硬化的中药配方
CN101850072A (zh) * 2010-05-06 2010-10-06 彭焕庭 一种治疗乙肝的中成药

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1203804A (zh) * 1998-05-04 1999-01-06 刘煌清 肝病康复全方药
CN1253830A (zh) * 1999-12-06 2000-05-24 黄培乐 治疗肝炎、胆管炎、胰腺炎、肝硬化的中药配方
CN101850072A (zh) * 2010-05-06 2010-10-06 彭焕庭 一种治疗乙肝的中成药

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
包剑锋等.慢性乙型肝炎中医辨治思考.《中国中医药学刊》.2007,第25卷(第5期),996-998.
慢性乙型肝炎中医辨治思考;包剑锋等;《中国中医药学刊》;20070531;第25卷(第5期);996-998 *
肝炎合剂治疗慢性乙型肝炎50例分析;陈巧彬;《中国当代医药》;20091231;第16卷(第25期);58-59 *
陈巧彬.肝炎合剂治疗慢性乙型肝炎50例分析.《中国当代医药》.2009,第16卷(第25期),58-59.

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