CN102579834A - Chinese herbal preparation for treating periodontitis - Google Patents

Abstract

The invention discloses a Chinese herbal preparation for treating periodontitis. The Chinese herbal preparation comprises an oral medicament and an externally applied drug, wherein the oral medicament is prepared from the following traditional Chinese medicine raw materials by weight portion: rhizoma cimicifugae, flos eriocauli, erythrina bark, leonurus, indian nightshade root, notopterygium root, teasel root, eggplant root, radix stemonae, scandent schefflera stems and leaves, licorice, coptidis rhizoma, sheathed aconite root, lotus stamen, nidus vespa, fructus arctii, water chestnut, gingko, peppermint oil and clove oil; and the externally applied drug is prepared from the following traditional Chinese medicine raw materials by weight portion: gypsum, native copper, alum, calomel, minium, mirabilite, dragon bone, sambucus williamsii hance, phoenix-tail fern, Indian nightshade root, eriocarpous glochidion leaves, herbal ecliptae, arisaema consanguineum schott, peppermint leaves, honeysuckle, bletilla formosana, rhubarb, rose leaves, ophioglossum vulgatum and Chinese gooseberry root. The Chinese herbal preparation takes traditional Chinese medicines as raw materials and is developed and prepared on the basis of theories of traditional Chinese medicine.

Description

A kind of Chinese medicine preparation of treating periodontitis

Technical field

The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation of treating periodontitis.

Background technology

Periodontitis is to invade GingivaWith periodontal tissue Chronic inflammatory disease, be a kind of destructive disease, its principal character does Periodontal pocketFormation and the bag wall inflammation, Frontal resorptionLoosening gradually with tooth, it is the main cause that causes adult's loss of tooth.Primary disease is many because of bacterial plaque, tartar, Food impaction, bad dummy is stung wound etc. and is caused, and various focusing depths represented swelling makes bacterial plaque pile up simultaneously and increases the weight of, and is expanded down by gingivally on the gum and to prolong.Because microecological environment under the gum is growing a large amount of bigger periodontal pathogenic bacterium of virulence, like the gingiva bacteroid in the subgingival plaque; Intermediate bacillus, spirillums etc. increase the weight of the inflammation of gingiva and expand and prolong; Cause periodontal pocket to form and frontal resorption, cause periodontitis.

Physician of all times has created the medicine of a large amount of treatment periodontal diseases in continuous exploration, and most medicines all are " curing the symptoms, not the disease ".Some effective prescriptions can only be because of human side, and often the cause of disease is not suited the medicine to the illness and poor effect.

Summary of the invention

The present invention provides a kind of Chinese medicine preparation of treating periodontitis in order to solve the weak point that exists in the prior art.

A kind of Chinese medicine preparation of treating periodontitis of the present invention forms through clinic tests and repeated verification for many years configuration, meets the theory of Chinese medicine.Prescription is to be raw material with the Chinese herbal medicine, processes required composition through selection → oven dry → pulverizing etc., after composite, processes powder agent, medicament, tablet, capsule again; Periodontitis treatment needs from adjusting general body state; Very important to the treatment local patholoic change, Just because of this, the present invention's Therapeutic Method from inside to outside; Both guarantee curative effect, reached treating both the principal and secondary aspects of a disease again.

A kind of Chinese medicine preparation of treating periodontitis comprises medicine for external use and oral medicine, and wherein medicine for external use is to be processed by following parts by weight of Chinese traditional medicine material combination:

Gypsum Fibrosum 20-30 part, Pyritum 20-30 part, Alumen 20-30 part, Calomelas 20-30 part, Plumbum preparatium 20-30 part, Natrii Sulfas 10-20 part, Os Draconis 10-20 part, Ramulus Sambuci Williamsii 10-20 part, Herba Pteridis Multifidae 10-20 part, Radix Solani indici 10-20 part, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 5-15 part, Herba Ecliptae 5-15 part, Rhizoma Arisaematis 5-15 part, mentha leave 5-15 part, Flos Lonicerae 5-15 part, Rhizoma Pleiones Yunnanensis 1-10 part, Radix Et Rhizoma Rhei 1-10 part, Folium rosae multiflorae 1-10 part, Herba Ophioglossi 1-10 part, Radix Actinidiae Chinensis 1-10 part;

The method for preparing of medicine for external use:

According to formula proportion above raw material is chosen → is dried → be crushed to 200-300 order fine powder → mix homogeneously to get product;

Oral medicine is to be formed by following parts by weight of Chinese traditional medicine material combination:

Rhizoma Cimicifugae 20-30 part, Flos Eriocauli 20-30 part, Cortex erythrinae 20-30 part, Herba Leonuri 20-30 part, Radix Solani indici 20-30 part, Rhizoma Et Radix Notopterygii 10-20 part, Radix Dipsaci 10-20 part, white Radix Solani Melongenae 10-20 part, Radix Stemonae 10-20 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-20 part, Radix Glycyrrhizae 5-15 part, Rhizoma Coptidis 5-15 part, Radix Aconiti Vaginati 5-15 part, Stamen Nelumbinis 5-15 part, Nidus Vespae 5-15 part, Fructus Arctii 1-10 part, Corm Eleocharitis 1-10 part, Semen Ginkgo 1-10 part, Oleum menthae 1-10 part, Oleum Caryophylli 1-10 part;

The oral medicine method for preparing:

Above-mentioned Chinese medicine is chosen → dried → be crushed to incapsulate behind 300-400 order fine powder → mix homogeneously and get product by formula proportion.

A kind of Chinese medicine preparation of treating periodontitis comprises medicine for external use and oral medicine, and wherein medicine for external use is to be processed by following parts by weight of Chinese traditional medicine material combination:

Gypsum Fibrosum 22-28 part, Pyritum 22-28 part, Alumen 22-28 part, Calomelas 22-28 part, Plumbum preparatium 22-28 part, Natrii Sulfas 12-18 part, Os Draconis 12-18 part, Ramulus Sambuci Williamsii 12-18 part, Herba Pteridis Multifidae 12-18 part, Radix Solani indici 12-18 part, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 6-14 part, Herba Ecliptae 6-14 part, Rhizoma Arisaematis 6-14 part, mentha leave 6-14 part, Flos Lonicerae 6-14 part, Rhizoma Pleiones Yunnanensis 2-8 part, Radix Et Rhizoma Rhei 2-8 part, Folium rosae multiflorae 2-8 part, Herba Ophioglossi 2-8 part, Radix Actinidiae Chinensis 2-8 part;

Oral medicine is to be formed by following parts by weight of Chinese traditional medicine material combination:

Rhizoma Cimicifugae 22-28 part, Flos Eriocauli 22-28 part, Cortex erythrinae 22-28 part, Herba Leonuri 22-28 part, Radix Solani indici 22-28 part, Rhizoma Et Radix Notopterygii 12-18 part, Radix Dipsaci 12-18 part, white Radix Solani Melongenae 12-18 part, Radix Stemonae 12-18 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12-18 part, Radix Glycyrrhizae 6-14 part, Rhizoma Coptidis 6-14 part, Radix Aconiti Vaginati 6-14 part, Stamen Nelumbinis 6-14 part, Nidus Vespae 6-14 part, Fructus Arctii 2-8 part, Corm Eleocharitis 2-8 part, Semen Ginkgo 2-8 part, Oleum menthae 2-8 part, Oleum Caryophylli 2-8 part.

A kind of Chinese medicine preparation of treating periodontitis comprises medicine for external use and oral medicine, and wherein medicine for external use is to be processed by following parts by weight of Chinese traditional medicine material combination:

25 parts in Gypsum Fibrosum, 25 parts of Pyritums, 25 parts of Alumens, 25 parts of Calomelass, 25 parts of Plumbum preparatiums, 15 parts in Natrii Sulfas, 15 parts of Os Draconis, 15 parts of Ramulus Sambuci Williamsii, 15 parts of Herba Pteridis Multifidaes, 15 parts of Radix Solani indicis, 10 parts of Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi)s, 10 parts of Herba Ecliptaes, 10 parts of Rhizoma Arisaematiss, 10 parts of mentha leavves, 10 parts of Flos Loniceraes, 5 parts of Rhizoma Pleiones Yunnanensiss, 5 parts of Radix Et Rhizoma Rhei, 5 parts of Folium rosae multifloraes, 5 parts of Herba Ophioglossis, 5 parts of Radix Actinidiae Chinensiss;

Oral medicine is to be formed by following parts by weight of Chinese traditional medicine material combination:

25 parts of Rhizoma Cimicifugaes, 25 parts of Flos Eriocaulis, 25 parts of Cortex erythrinaes, 25 parts of Herba Leonuris, 25 parts of Radix Solani indicis, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Radix Dipsacis, 15 parts of white Radix Solani Melongenaes, 15 parts of the Radixs Stemonae, 15 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, 10 parts in Radix Glycyrrhizae, 10 parts of Rhizoma Coptidis, 10 parts of Radix Aconiti Vaginatis, 10 parts of Stamen Nelumbiniss, 10 parts of Nidus Vespaes, 5 parts of Fructus Arctiis, 5 parts of Corm Eleocharitiss, 5 parts of Semen Ginkgoes, 5 parts of Oleum menthae, 5 parts of Oleum Caryophyllis.

The herbal pharmacology and the property of medicine that the present invention relates to are following:

Rhizoma Cimicifugae:

[meridian distribution of property and flavor] is sweet, hot, cool.Return spleen, stomach, large intestine channel.

[drug effect] relieve internal heat anticancer, rash is analgesic, doctor's skin ulcer eliminating carbuncle.

Flos Eriocauli:

[meridian distribution of property and flavor] Xin Gan, cold.1. supplement to the Herbal: " sweet in the mouth, flat." 2. " Japan hanako materia medica ": " cold." go into liver, stomach warp." Bencao Jingshu ": " go into the sufficient bright warp of yin, yang of fainting.”

[effect] wind and heat eliminating, improving acuity of vision and removing nebula.

[curing mainly] controlled corneal nebula, night blindness, headache, toothache, sore throat, epistaxis.

Cortex erythrinae: wind-damp dispelling, the meridian dredging, parasite killing.Cure mainly: dispelling the wind and dampness pathogens arthralgia pain, dysentery, toothache, scabies.

Herba Leonuri:

[meridian distribution of property and flavor] is bitter, hot, is slightly cold; Return liver, pericardium channel.

[function cures mainly] promoting blood flow to regulate menstruation, inducing diuresis to remove edema.Be used for menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.

Radix Solani indici:

[nature and flavor] hardship, flat.1. " the SHENGCAO property of medicine is wanted fully ": bitter in the mouth.2. " south of the Five Ridges gather medicinal herbs record ": bitter in the mouth, cold in nature.3. " Nanning City's medicine will ": hardship, flat.4. Guangzhou air force " Chinese herbal medicine handbook commonly used: light, cold, slightly poisonous.

[function cures mainly] removing damp-heat, removing blood stasis to reduce swelling.The dispelling the wind and dampness pathogens arthralgia pain, eruptive disease stomachache, headache, toothache, pharyngitis, tonsillitis, infantile malnutrition, traumatic injury, scrofula.1. " the SHENGCAO property of medicine is wanted fully ": traumatic injury is checkmated, pot wine clothes.2. " Nanning City's medicine will ": heat clearing away, quench the thirst cough-relieving.Control the eruptive disease belly pain, five kinds of child malnutrition, fever of children, snakebite.3. Guangzhou air force " Chinese herbal medicine handbook commonly used: dissipating blood stasis for subsidence of swelling, anti-inflammatory analgetic.Control pharyngitis, tonsillitis, lymphadenitis, stomachache.

Rhizoma Et Radix Notopterygii:

[meridian distribution of property and flavor] acrid in the mouth, hardship, temperature.Go into bladder, kidney channel.

[function cures mainly] exterior cold of loosing, wind-damp dispelling, sharp joint.The wind and cold that cures cold, it is lossless to have a headache, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema.

Radix Dipsaci:

[meridian distribution of property and flavor] bitter in the mouth, suffering, tepor is returned liver, kidney channel.

[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, continuous folding is hindered, and ends metrorrhagia.Be used for soreness of the waist and knees, rheumatic arthralgia, metrorrhagia, vaginal bleeding during pregnancy, injury from falling down.Prepared RADIX DIPSACI with yellow rice wine is used for rheumatic arthralgia more, injury from falling down.Prepared RADIX DIPSACI with salt solution is used for soreness of the waist and knees more." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " meridians decide in tonifying liver, bone and muscle strengthening, end in the warp (muscles and bones) and ache, and are antiabortive, control the married woman leucorrhea, tissue regeneration promoting blood, and removing blood stasis with potent drugs blood, the stillborn fetus that falls, the cough-relieving hemoptysis of coughing is controlled red white turbid urine.”

White Radix Solani Melongenae:

[nature and flavor] are sweet, and are cold.

[effectiveness] invigorates blood circulation, detumescence, chilblain, arthralgia.

The Radix Stemonae:

[meridian distribution of property and flavor] is sweet, bitter, tepor.Return lung meridian.

The cough-relieving of [function cures mainly] nourishing the lung to keep the adverse QI downward, parasite killing.Be used for new chronic cough and cough, pulmonary tuberculosis cough, pertussis; Be used for head louse outward, body louse, enterobiasis, pudendal pruritus.Honey Radix Stemonae nourishing the lung to arrest cough.Be used for deficiency of YIN chronic cough.

Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae):

[nature and flavor] little hardship, temperature, 1. " Guangxi Chinese herbal medicine ": warm in nature, acrid in the mouth.2. Guangzhou army " Chinese herbal medicine handbook commonly used: bitter sweet, temperature.

[function cures mainly] expelling wind and removing dampness, promoting blood circulation and stopping pain.The dispelling the wind and dampness pathogens arthralgia pain, stomachache, injury and bone fracture, traumatic hemorrhage.

Radix Glycyrrhizae:

[meridian distribution of property and flavor] is sweet, and be flat, GUIXIN, lung, spleen, stomach warp.

[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription is used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

Rhizoma Coptidis:

[meridian distribution of property and flavor] hardship, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.

[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, the vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, the carbuncle furuncle is quenched one's thirst in toothache; External treatment eczema, eczema, auditory meatus is suppurated.The kind clear part of the body cavity above the diaphragm housing the heart and lungs of Rhizoma Coptidis (processed with wine) is burning hot.Be used for conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Be used for cold and heat and tie mutually, damp and hot middle resistance, feeling of fullness vomiting.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.Be used for incoordination between the liver and stomach, the vomiting acid regurgitation.

Radix Aconiti Vaginati:

[nature and flavor] " Guizhou folk medicine ": " warm in nature, acrid in the mouth, slightly poisonous."

[function cures mainly] controlled cough with asthma, menoxenia, traumatic injury.1. " Guizhou folk medicine ": " promoting blood flow to regulate menstruation, pain relieving." 2. control traumatic injury, reduce phlegm, cough-relieving is breathed heavily.Innominate toxic swelling is wiped in external.(" Acta Pharmaceutica Sinica " 10:692,1965)

Stamen Nelumbinis:

[nature and flavor] are sweet, puckery, and are flat.

[return through] GUIXIN, kidney channel.

[function cures mainly] reinforcing the kindey to control nocturnal emission.Be used for emission and spermatorrhea, leukorrhagia, UrineFrequently.

Nidus Vespae:

Flat, the mild toxicity of little sweet, the property of [meridian distribution of property and flavor] flavor; Return liver, stomach, kidney channel.

[function cures mainly] wind-expelling pain-stopping; The detumescence of rose poison; Killing parasites for relieving itching.Main air temperature arthralgia pain; The wind carious pain; The carbuncle malignant boil; Scrofula; Mouthpiece swells and ache; Anal fistula; The rubella pruritus; Skin stubborn dermatitis.

Fructus Arctii:

[nature and flavor] acrid in the mouth; Bitter; Cold in nature.Return lung; The stomach warp.

[function cures mainly] anemopyretic cold, epidemic febrile disease from the beginning of; Wind heat or cough due to lung-heat, cough up phlegm not smooth; Laryngopharynx swelling and painMacule is not passed through; At the measles initial stage, rash does not go out and freely reaches RubellaPruritus; Skin infectionToxic swelling and mumps etc.But give birth to loosening bowel to relieve constipation, the pyretic toxicity red swelling and pain of throat, it is suitable especially to have constipation with heat retention concurrently.The rats by intraperitoneal injection aminonucleoside causes nephropathy, and the lumbar injection aretigenin can suppress Urine proteinExcretory increase, and can improve SerumBiochemical indicator, prompting has anti- NephropathyEffect.

Corm Eleocharitis:

[meridian distribution of property and flavor] bulb: sweet, cold;

[function cures mainly] bulb: relieve heat and thirst, dampness removing reduces phlegm, blood pressure lowering.Be used for the consumption of body fluid caused by febrile disease excessive thirst, laryngopharynx swelling and pain, stomatitis is damp and hot Jaundice, hypertension, dysuria, measles, Lung-heatCough, Pneumosilicosis, HemorrhoidHemorrhage.The Corm Eleocharitis mouthfeel is sweet crisp, and is nutritious, contain protein, fat, Crude fibre, Carotene, Vitamin B, Vitamin C, Ferrum, Calcium, PhosphorusAnd carbohydrate.Can eat something rare, also can be used for cooking, can make Starch, also can do Chinese medicine

Semen Ginkgo:

[nature and flavor] are sweet; Bitter; Puckery; Property is put down; Mild toxicity.

[return through] Lung meridian Kidney channel

[function] astringing lung QI for relieving asthma; The leukorrhagia stopping reducing urination.

[curing mainly] asthma phlegmatic cough; Leucorrhea; Nebulousurine; Seminal emission; Frequent micturition; Innominate toxic swelling; The Zha nose; The tinea skin ulcer.

Oleum menthae:

[nature and flavor] " Chinese medicine voluminous dictionary ": " suffering, cold, nontoxic."

[function] aromatic drug, remedium corrigens and carminative.Function: can be used for skin or mucosa and produce refrigerant sense cannot not alleviate suitablely main pain.The irritation effect causes trachea to produce new secretion, and makes stiff mucus be easy to get rid of, so eliminate the phlegm, germ-resistant effect.

Oleum Caryophylli:

[meridian distribution of property and flavor] acrid in the mouth, sweet, hot in nature; Return spleen, stomach, kidney channel.

[function] warming the stomach; Sending down the abnormal ascending QI; Wet kidney.Main cold syndrome of the stomach pain with distension; Singultus; Vomit and diarrhoea; Arthralgia pain; Colic; Halitosis; Toothache.

Gypsum Fibrosum:

[meridian distribution of property and flavor] Xin Gan, cold.1. " Herbal classic": " acrid in the mouth is slightly cold." 2. " Lu not": " sweet, Great Cold, nontoxic." 3. " medicine origin ": " and " curing mainly secret formula " cloud, cold in nature, lightly seasoned." go into lung, stomach warp.1. " The Decoction and Material Medica": " lunar, few sun of starting with, sufficient Yangming Channel." 2. " Amplification on Materia Medica addendum ": " go into that sun is bright, hands is lunar, the few sun of hands.”

[function cures mainly] controlled the calentura high fever and do not moved back, vexed coma, and delirium is gone mad, thirsty and dry pharynx, the lung-heat dyspnea with rapid respiration, the heatstroke spontaneous perspiration, Stomach-fireHeadache, toothache, hyperactivity of toxic heat is sent out the speckle dermexanthesis, aphtha of the mouth and tongue.Forge deposited promoting tissue regeneration and ulcer healing.External treatment CarbuncleSkin infection is burst and is not closed up the burning hot wound of soup.Efficacy of drugs: expelling pathogenic factors from muscles for clearing heat, relieving restlessness quench the thirst, heat-clearing and toxic substances removing.

Pyritum:

[meridian distribution of property and flavor] acrid in the mouth is flat.Dissipating blood stasis, synthetism, pain relieving.

[function cures mainly] is used for treating swelling and pain by traumatic injury, and the muscles and bones folding is hindered.Go into the diffusing clothes of ball more; External is ground into powder to transfer and is applied.

Alumen:

[meridian distribution of property and flavor] sour in the mouth, cold.Go into spleen channel.

The sputum of [function] vomiting and diarrhea wind heat is got its sour and bitter flavors can cause of vomiting and diarrhea also; Control all disorders of blood, proctoptosis, the prolapse of the uterus, skin infection, get that it is sour and astringent and receive also; Control phlegm retention, let out profit, metrorrhagia and leukorrhagia, wind-eye, get its receipts and dampness also; Control sore throat, carbuncle of yin nature, middle legendary venomous insect, snakeworm and hinder Trionyx sinensis Wiegmann, get its detoxifcation also.

Calomelas:

[nature and flavor] are hot, cold, poisonous, go into liver, kidney channel;

[effect] counteracting toxic substances, diuretic, relieving constipation, control scabies, scrofula, syphilis, primary sore, skin ulcer, edema, tympanites, defecation is closed.

The Plumbum preparatium:

[meridian distribution of property and flavor] acrid in the mouth, little salty, little puckery is gone into the heart, spleen, Liver Channel;

[effect] detoxifcation, granulation promoting, eliminating phlegm down to arrest convulsion.Control carbuncle, ulcer, incised wound is hemorrhage, aphtha, and corneal nebula, the soup fire ， Jing Epilepsy of burning is demented, malaria, dysentery is told converse stomach.

Natrii Sulfas:

[meridian distribution of property and flavor] is cold in nature, and salty in the mouth, little hardship are gone into stomach, large intestine channel.

[function] has moistening for dryness and softening hard mass, purging heat to relax the bowels effect, and external also has heat-clearing and toxic substances removing, removing blood stasis promoting the circulation of blood, mass dissipating and swelling eliminating.

Os Draconis:

[nature and flavor] sweet in the mouth, puckery is flat.

[function cures mainly] astringing QI ends night sweat by wet, calms the nerves unsmoothing the sperm and stopping bleeding.Control the night sweat that crouches night, nocturnal emission, spermatorrhea, discharging fresh blood stool, dysentery is told epistaxis, metrorrhagia and leukorrhagia.External can be held back the open sore part.Decoct or go into ball and loose.Deposited affected part is ground in external into powder.

Ramulus Sambuci Williamsii:

[meridian distribution of property and flavor] sweet in the mouth, hardship, flat, return Liver Channel.

[function cures mainly] reunion of bone, promoting blood circulation and stopping pain, expelling wind and removing dampness.Be used for fracture, traumatic injury, rheumatic arthritis, gout, Kaschin-Beck disease, acute and chronic nephritis; Wound hemorrhage is controlled in external.

Herba Pteridis Multifidae:

[meridian distribution of property and flavor] light, little hardship, cold.

[function cures mainly] clearing away heat-damp and promoting diuresis, the detoxifcation dysentery relieving, cooling blood for hemostasis is used for dysentery, gastroenteritis, hepatitis, urinary system infection, cat fever, laryngopharynx swelling and pain, leucorrhea, metrorrhagia, pesticide intoxication; Traumatic hemorrhage is controlled in external, burn and scald.

Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi):

[meridian distribution of property and flavor] bitter but sweet flavor is puckery, and property is flat;

[effect] dispelling wind and dampness, dissipating blood stasis, hemostasis, detumescence.Cure mainly acute gastroenteritis, dysentery, rheumatic arthritis, traumatic injury, wound hemorrhage, dermatitis rhus, eczema, dermatitis; Control Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) allergy, paddy field dermatitis, skin pruritus, exfoliative dermatitis, urticaria, eczema: bright leaf of Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) or cured leaf, decoction being used as a lotion.

Herba Ecliptae:

[meridian distribution of property and flavor] is sweet, sour, and be cold.Return kidney, Liver Channel.1. Tang Materia Medica: " sweet in the mouth acid, flat, nontoxic." 2. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " and cold in nature, salty in the mouth." go into liver, kidney channel.1. " Bencao Jingshu ": " go into kidney, liver.Stomach, intestine and small intestine." 2. " must join book on Chinese herbal medicine ": " go into the meridian of Foot-SHAO YIN blood system.”

[function cures mainly] nourishing the liver and kidney, cooling blood for hemostasis.Be used for odontoseisis, early whitening of beard and hair, vertigo and tinnitus, the acid of waist knee joint, deficiency of YIN heat in blood, haematemesis, blood nosebleed, hematuria, dysentery, metrostaxis, traumatic hemorrhage.

Rhizoma Arisaematis:

[meridian distribution of property and flavor] is bitter, hot, temperature; Poisonous.Return lung, liver, spleen channel.

[function cures mainly] drying dampness to eliminate phlegm is expellingged wind and relieving convulsion mass dissipating and swelling eliminating.Be used for the pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia, epilepsy, infantile convulsion, tetanus.Give birth to and use external treatment carbuncle, snake bite and insect sting.

Mentha leave:

[meridian distribution of property and flavor] cool in nature, acrid in the mouth;

The effect of [function] irritation causes trachea to produce new secretion, and makes stiff mucus be easy to get rid of, so eliminate the phlegm, germ-resistant effect.

Flos Lonicerae:

[nature and flavor] property is sweet, cold;

[function] has heat clearing away, detoxifcation, antiinflammatory, antibiotic effect.Compendium of Material Medica is carried " Flos Lonicerae is good at removing toxic substances, so control carbuncle, toxic swelling, skin ulcer tinea ... ".Since ancient times, Flos Lonicerae is usually used in heat-clearing and toxic substances removing, the heating of treatment epidemic febrile disease, and toxic-heat and blood stasis, diseases such as carbuncle and ulcer also are used for diseases such as anemopyretic cold, bronchitis.Modern pharmacological research shows, that Flos Lonicerae has is antibacterial, antiviral, antiinflammatory, analgesic, regulate effect such as immunity.

Rhizoma Pleiones Yunnanensis:

[nature and flavor] " Yunnan Chinese herbal medicine ": hardship, flat.

[function cures mainly] tonifying the lung, relieving cough and resolving phlegm, hemostasia and promoting granulation.Control pneumosilicosis, pulmonary tuberculosis, pertussis, trachea, digestive tract hemorrhage, carbuncle, traumatic hemorrhage.1. " Yunnan Chinese herbal medicine ": relieving cough and resolving phlegm, tonifying the lung granulation promoting.2. " the Guizhou medicine is planted catalogue ": heat-clearing and toxic substances removing, cough-relieving.3. " choosing of Yunnan Chinese herbal medicine ": lung moistening, hemostasis.Control pneumosilicosis, pulmonary tuberculosis, tracheitis, digestive tract hemorrhage, traumatic hemorrhage, furuncle and phyma, traumatic injury.

Radix Et Rhizoma Rhei:

[meridian distribution of property and flavor] bitter in the mouth, cold; Return spleen, stomach, large intestine, liver, pericardium channel.

[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Be used for the excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.Be used for the conjunctival congestion pharyngeal swelling, gums is swollen.Radix Et Rhizoma Rhei rushes down exerts oneself to delay eliminating fire and detoxication.Be used for pathogenic fire,toxin and furuncles.The hemostasis of charred Radix Et Rhizoma Rhei cooling blood and removing stasis.Be used for heat in blood stasis of blood hemorrhage is arranged.

Folium rosae multiflorae:

[meridian distribution of property and flavor] puckery, flat spleen channel.

[function cures mainly] " Nanning City's medicine will ": " mash external application, promoting tissue regeneration and wound healing."

Herba Ophioglossi:

[nature and flavor] are little sweet, bitter, cold.

[function cures mainly] claimed Ophioglossum vulgatum again; Removing heat from blood, heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Cure mainly: laryngalgia, sore throat, diphtheria, oral disease, infantile pneumonia, abdominal distention, venom is treated pyogenic infections from tumour or sore; Acute conjunctivitis is controlled in external, corneal nebula, and margo palpebrae is scorching.

Radix Actinidiae Chinensis:

[nature and flavor] " Shaanxi Chinese herbal medicine ": " acid is little sweet, and cold is slightly poisonous."

[function cures mainly] heat clearing away, diuresis is invigorated blood circulation, detumescence.Treating the liver is scorching, edema, traumatic injury, rheumatic arthritis, stranguria with turbid discharge, leukorrhagia, furuncle, scrofula.1. " Guizhou side's medicine among the people collection ": " diuresis, cathartic.Control ascites; The external synthetism, wound disappears." 2. " Zhejiang medical herbs commonly used among the people ": " is good for the stomach, and invigorates blood circulation lactogenic, antiinflammatory." 3. " Shaanxi Chinese herbal medicine ": " heat-clearing and toxic substances removing, promoting blood circulation and detumescence, anticancer.Control furuncle, scrofula."

The practical implementation method:

Embodiment 1, prescription:

Medicine for external use is to be processed by following Chinese medicine raw materials by weight proportion compatibility:

Gypsum Fibrosum 20g, Pyritum 20g, Alumen 20g, Calomelas 20g, Plumbum preparatium 20g, Natrii Sulfas 10g, Os Draconis 10g, Ramulus Sambuci Williamsii 10g, Herba Pteridis Multifidae 10g, Radix Solani indici 10g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 5g, Herba Ecliptae 5g, Rhizoma Arisaematis 5g, mentha leave 5g, Flos Lonicerae 5g, Rhizoma Pleiones Yunnanensis 1g, Radix Et Rhizoma Rhei 1g, Folium rosae multiflorae 1g, Herba Ophioglossi 1g, Radix Actinidiae Chinensis 1g;

The method for preparing of medicine for external use:

According to formula proportion above raw material is chosen → is dried → be crushed to 200-300 order fine powder → mix homogeneously to get product;

Oral medicine is to be formed by following Chinese medicine raw materials by weight proportion compatibility:

Rhizoma Cimicifugae 20g, Flos Eriocauli 20g, Cortex erythrinae 20g, Herba Leonuri 20g, Radix Solani indici 20g, Rhizoma Et Radix Notopterygii 10g, Radix Dipsaci 10g, white Radix Solani Melongenae 10g, Radix Stemonae 10g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10g, Radix Glycyrrhizae 5g, Rhizoma Coptidis 5g, Radix Aconiti Vaginati 5g, Stamen Nelumbinis 5g, Nidus Vespae 5g, Fructus Arctii 1g, Corm Eleocharitis 1g, Semen Ginkgo 1g, Oleum menthae 1g, Oleum Caryophylli 1g;

The oral medicine method for preparing:

Above-mentioned Chinese medicine is chosen → dried → be crushed to incapsulate behind 300-400 order fine powder → mix homogeneously and get product by formula proportion.

Embodiment 2, prescription:

Medicine for external use is to be processed by following Chinese medicine raw materials by weight proportion compatibility:

Gypsum Fibrosum 22g, Pyritum 22g, Alumen 22g, Calomelas 22g, Plumbum preparatium 22g, Natrii Sulfas 12g, Os Draconis 12g, Ramulus Sambuci Williamsii 12g, Herba Pteridis Multifidae 12g, Radix Solani indici 12g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 6g, Herba Ecliptae 6g, Rhizoma Arisaematis 6g, mentha leave 6g, Flos Lonicerae 6g, Rhizoma Pleiones Yunnanensis 2g, Radix Et Rhizoma Rhei 2g, Folium rosae multiflorae 2g, Herba Ophioglossi 2g, Radix Actinidiae Chinensis 2g;

Oral medicine is to be formed by following Chinese medicine raw materials by weight proportion compatibility:

Rhizoma Cimicifugae 22g, Flos Eriocauli 22g, Cortex erythrinae 22g, Herba Leonuri 22g, Radix Solani indici 22g, Rhizoma Et Radix Notopterygii 12g, Radix Dipsaci 12g, white Radix Solani Melongenae 12g, Radix Stemonae 12g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12g, Radix Glycyrrhizae 6g, Rhizoma Coptidis 6g, Radix Aconiti Vaginati 6g, Stamen Nelumbinis 6g, Nidus Vespae 6g, Fructus Arctii 2g, Corm Eleocharitis 2g, Semen Ginkgo 2g, Oleum menthae 2g, Oleum Caryophylli 2g.

Method for preparing is identical with embodiment 1.

Embodiment 3, prescription:

Medicine for external use is to be processed by following Chinese medicine raw materials by weight proportion compatibility:

Gypsum Fibrosum 25g, Pyritum 25g, Alumen 25g, Calomelas 25g, Plumbum preparatium 25g, Natrii Sulfas 15g, Os Draconis 15g, Ramulus Sambuci Williamsii 15g, Herba Pteridis Multifidae 15g, Radix Solani indici 15g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 10g, Herba Ecliptae 10g, Rhizoma Arisaematis 10g, mentha leave 10g, Flos Lonicerae 10g, Rhizoma Pleiones Yunnanensis 5g, Radix Et Rhizoma Rhei 5g, Folium rosae multiflorae 5g, Herba Ophioglossi 5g, Radix Actinidiae Chinensis 5g;

Oral medicine is to be formed by following Chinese medicine raw materials by weight proportion compatibility:

Rhizoma Cimicifugae 25g, Flos Eriocauli 25g, Cortex erythrinae 25g, Herba Leonuri 25g, Radix Solani indici 25g, Rhizoma Et Radix Notopterygii 15g, Radix Dipsaci 15g, white Radix Solani Melongenae 15g, Radix Stemonae 15g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 15g, Radix Glycyrrhizae 10g, Rhizoma Coptidis 10g, Radix Aconiti Vaginati 10g, Stamen Nelumbinis 10g, Nidus Vespae 10g, Fructus Arctii 5g, Corm Eleocharitis 5g, Semen Ginkgo 5g, Oleum menthae 5g, Oleum Caryophylli 5g.

Method for preparing is identical with embodiment 1.

Embodiment 4, prescription:

Medicine for external use is to be processed by following Chinese medicine raw materials by weight proportion compatibility:

Gypsum Fibrosum 28g, Pyritum 28g, Alumen 28g, Calomelas 28g, Plumbum preparatium 28g, Natrii Sulfas 18g, Os Draconis 18g, Ramulus Sambuci Williamsii 18g, Herba Pteridis Multifidae 18g, Radix Solani indici 18g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 14g, Herba Ecliptae 14g, Rhizoma Arisaematis 14g, mentha leave 14g, Flos Lonicerae 14g, Rhizoma Pleiones Yunnanensis 8g, Radix Et Rhizoma Rhei 8g, Folium rosae multiflorae 8g, Herba Ophioglossi 8g, Radix Actinidiae Chinensis 8g;

Oral medicine is to be formed by following Chinese medicine raw materials by weight proportion compatibility:

Rhizoma Cimicifugae 28g, Flos Eriocauli 28g, Cortex erythrinae 28g, Herba Leonuri 28g, Radix Solani indici 28g, Rhizoma Et Radix Notopterygii 18g, Radix Dipsaci 18g, white Radix Solani Melongenae 18g, Radix Stemonae 18g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 18g, Radix Glycyrrhizae 14g, Rhizoma Coptidis 14g, Radix Aconiti Vaginati 14g, Stamen Nelumbinis 14g, Nidus Vespae 14g, Fructus Arctii 8g, Corm Eleocharitis 8g, Semen Ginkgo 8g, Oleum menthae 8g, Oleum Caryophylli 8g.

Method for preparing is identical with embodiment 1.

Embodiment 5, prescription:

Medicine for external use is to be processed by following Chinese medicine raw materials by weight proportion compatibility:

Gypsum Fibrosum 30g, Pyritum 30g, Alumen 30g, Calomelas 30g, Plumbum preparatium 30g, Natrii Sulfas 20g, Os Draconis 20g, Ramulus Sambuci Williamsii 20g, Herba Pteridis Multifidae 20g, Radix Solani indici 20g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 15g, Herba Ecliptae 15g, Rhizoma Arisaematis 15g, mentha leave 15g, Flos Lonicerae 15g, Rhizoma Pleiones Yunnanensis 10g, Radix Et Rhizoma Rhei 10g, Folium rosae multiflorae 10g, Herba Ophioglossi 10g, Radix Actinidiae Chinensis 10g;

Oral medicine is to be formed by following Chinese medicine raw materials by weight proportion compatibility:

Rhizoma Cimicifugae 30g, Flos Eriocauli 30g, Cortex erythrinae 30g, Herba Leonuri 30g, Radix Solani indici 30g, Rhizoma Et Radix Notopterygii 20g, Radix Dipsaci 20g, white Radix Solani Melongenae 20g, Radix Stemonae 20g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 20g, Radix Glycyrrhizae 15g, Rhizoma Coptidis 15g, Radix Aconiti Vaginati 15g, Stamen Nelumbinis 15g, Nidus Vespae 15g, Fructus Arctii 10g, Corm Eleocharitis 10g, Semen Ginkgo 10g, Oleum menthae 10g, Oleum Caryophylli 10g;

Method for preparing is identical with embodiment 1.

Treatment periodontal disease observation of curative effect:

The symptom of periodontitis mainly shows as red swelling of gingiva, hemorrhage, and is not only hemorrhage when brushing teeth, and also hemorrhage when speaking or stinging hard thing sometimes, idol also can have spontaneous hemorrhage.Therefore, control over bleeding, recurrence have crucial meaning to the treatment primary disease.We adopt the Chinese medicine preparation of treating the Asia inflammation in 2009-2011, and treatment periodontal disease 100 examples obtain good result, the existing summary as follows.

The health giving quality observation index

Main curative effect index: red swelling of gingiva, gingival hemorrhage, pyorrhea, Halitosis, odontoseisis, elongation, displacement, pain,

Secondary efficacy index: stool, urine, picture of the tongue, pulse condition.

The model case curative effect determinate standard:

Local disease is decreased evaluation criteria and is as the criterion with gingiva healing degree and the scorching hot degree of pain.

Clinical recovery: medication is transference cure after 5 days, and sign disappears basically, and periodontitis decreases all healings, and the leading indicator integration is 0 or 1.

Produce effects: medication is transference cure after 1 day, and sign all has clear improvement, and periodontal disease healing reaches 2/3 or hemorrhage dwindling, and it is 2 that the leading indicator integration is 1, two.

Effectively: medication is transference cure after 1 day, and sign all take a favorable turn, and periodontitis healing reaches 1/3 or hemorrhage dwindling, and it is 3 that the leading indicator integration is 2, two.

Invalid: medication cardinal symptom after 3 days, sign are improved not obvious, and the basic no change of Asia inflammation, leading indicator integration are 3 or 4.

Therapeutic outcome is seen table

Age	Recovery from illness	Produce effects	Invalid	Effective percentage (%)
					Below 10 years old	20	20	---	100%
10-35 year	40	40	---	100%
					35-55 year	36	25	4	96.6%
More than 55 years old	4	3	1	99%

In sum: recovery from illness clinical improvements rate >=95%; Produce effects clinical improvements rate＜95%, >=60%;

Invalid clinical improvements rate＜10%.

Claims (3)

1. a Chinese medicine preparation of treating periodontitis comprises medicine for external use and oral medicine, it is characterized in that, medicine for external use is to be processed by following parts by weight of Chinese traditional medicine material combination:

Gypsum Fibrosum 20-30 part, Pyritum 20-30 part, Alumen 20-30 part, Calomelas 20-30 part, Plumbum preparatium 20-30 part, Natrii Sulfas 10-20 part, Os Draconis 10-20 part, Ramulus Sambuci Williamsii 10-20 part, Herba Pteridis Multifidae 10-20 part, Radix Solani indici 10-20 part, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 5-15 part, Herba Ecliptae 5-15 part, Rhizoma Arisaematis 5-15 part, mentha leave 5-15 part, Flos Lonicerae 5-15 part, Rhizoma Pleiones Yunnanensis 1-10 part, Radix Et Rhizoma Rhei 1-10 part, Folium rosae multiflorae 1-10 part, Herba Ophioglossi 1-10 part, Radix Actinidiae Chinensis 1-10 part;

The method for preparing of medicine for external use:

According to formula proportion above raw material is chosen → is dried → be crushed to 200-300 order fine powder → mix homogeneously to get product;

Oral medicine is to be formed by following parts by weight of Chinese traditional medicine material combination:

Rhizoma Cimicifugae 20-30 part, Flos Eriocauli 20-30 part, Cortex erythrinae 20-30 part, Herba Leonuri 20-30 part, Radix Solani indici 20-30 part, Rhizoma Et Radix Notopterygii 10-20 part, Radix Dipsaci 10-20 part, white Radix Solani Melongenae 10-20 part, Radix Stemonae 10-20 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-20 part, Radix Glycyrrhizae 5-15 part, Rhizoma Coptidis 5-15 part, Radix Aconiti Vaginati 5-15 part, Stamen Nelumbinis 5-15 part, Nidus Vespae 5-15 part, Fructus Arctii 1-10 part, Corm Eleocharitis 1-10 part, Semen Ginkgo 1-10 part, Oleum menthae 1-10 part, Oleum Caryophylli 1-10 part;

The oral medicine method for preparing:

Above-mentioned Chinese medicine is chosen → dried → be crushed to incapsulate behind 300-400 order fine powder → mix homogeneously and get product by formula proportion.

2. a Chinese medicine preparation of treating periodontitis comprises medicine for external use and oral medicine, it is characterized in that, medicine for external use is to be processed by following parts by weight of Chinese traditional medicine material combination:

Gypsum Fibrosum 22-28 part, Pyritum 22-28 part, Alumen 22-28 part, Calomelas 22-28 part, Plumbum preparatium 22-28 part, Natrii Sulfas 12-18 part, Os Draconis 12-18 part, Ramulus Sambuci Williamsii 12-18 part, Herba Pteridis Multifidae 12-18 part, Radix Solani indici 12-18 part, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 6-14 part, Herba Ecliptae 6-14 part, Rhizoma Arisaematis 6-14 part, mentha leave 6-14 part, Flos Lonicerae 6-14 part, Rhizoma Pleiones Yunnanensis 2-8 part, Radix Et Rhizoma Rhei 2-8 part, Folium rosae multiflorae 2-8 part, Herba Ophioglossi 2-8 part, Radix Actinidiae Chinensis 2-8 part;

Oral medicine is to be formed by following parts by weight of Chinese traditional medicine material combination:

Rhizoma Cimicifugae 22-28 part, Flos Eriocauli 22-28 part, Cortex erythrinae 22-28 part, Herba Leonuri 22-28 part, Radix Solani indici 22-28 part, Rhizoma Et Radix Notopterygii 12-18 part, Radix Dipsaci 12-18 part, white Radix Solani Melongenae 12-18 part, Radix Stemonae 12-18 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12-18 part, Radix Glycyrrhizae 6-14 part, Rhizoma Coptidis 6-14 part, Radix Aconiti Vaginati 6-14 part, Stamen Nelumbinis 6-14 part, Nidus Vespae 6-14 part, Fructus Arctii 2-8 part, Corm Eleocharitis 2-8 part, Semen Ginkgo 2-8 part, Oleum menthae 2-8 part, Oleum Caryophylli 2-8 part.

3. a Chinese medicine preparation of treating periodontitis comprises medicine for external use and oral medicine, it is characterized in that, medicine for external use is to be processed by following parts by weight of Chinese traditional medicine material combination:

25 parts in Gypsum Fibrosum, 25 parts of Pyritums, 25 parts of Alumens, 25 parts of Calomelass, 25 parts of Plumbum preparatiums, 15 parts in Natrii Sulfas, 15 parts of Os Draconis, 15 parts of Ramulus Sambuci Williamsii, 15 parts of Herba Pteridis Multifidaes, 15 parts of Radix Solani indicis, 10 parts of Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi)s, 10 parts of Herba Ecliptaes, 10 parts of Rhizoma Arisaematiss, 10 parts of mentha leavves, 10 parts of Flos Loniceraes, 5 parts of Rhizoma Pleiones Yunnanensiss, 5 parts of Radix Et Rhizoma Rhei, 5 parts of Folium rosae multifloraes, 5 parts of Herba Ophioglossis, 5 parts of Radix Actinidiae Chinensiss;

Oral medicine is to be formed by following parts by weight of Chinese traditional medicine material combination:

25 parts of Rhizoma Cimicifugaes, 25 parts of Flos Eriocaulis, 25 parts of Cortex erythrinaes, 25 parts of Herba Leonuris, 25 parts of Radix Solani indicis, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Radix Dipsacis, 15 parts of white Radix Solani Melongenaes, 15 parts of the Radixs Stemonae, 15 parts of Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s, 10 parts in Radix Glycyrrhizae, 10 parts of Rhizoma Coptidis, 10 parts of Radix Aconiti Vaginatis, 10 parts of Stamen Nelumbiniss, 10 parts of Nidus Vespaes, 5 parts of Fructus Arctiis, 5 parts of Corm Eleocharitiss, 5 parts of Semen Ginkgoes, 5 parts of Oleum menthae, 5 parts of Oleum Caryophyllis.