Chinese medicine snuffing antiperspirant steams the immunotherapy of treatment tumor
Technical field
The invention belongs to the Chinese medicine ointment is medicine, adopts nasal administration, and antiperspirant steams the immunotherapy of toxin expelling treatment tumor.
Background technology
Tumor (Tumor) be body under various carcinogenic factor effects, some cells of local organization lose the normal regulation to its growth on gene level, cause its clonal abnormality hypertrophy and the neoplasm that forms.The cause of cancer at first is an equilibrium between yin and yang in the human body, and histiocyte is under different carcinogenic factor long terms, and cell mutation causes, it mainly show the unusual and over-drastic hypertrophy of histiocyte.Cancerous tissue also is the part of human body in fact, and only at this imbalance between YIN and YANG of people, generation-inhibition in five elements is taken advantage of and insulted under the prerequisite that changes, and the immune monitoring system of human body just can lose monitoring to it, develops as one pleases.In the course of time, cancerous cell is bred day by day, and tumor troop grows stronger day by day, and corrodes normal surrounding tissue at last, consumes significant amount of energy and nutrition, influences the body normal physiological metabolism, causes body depleted gradually, finally causes death.
Motherland's medical science thinks that human body structurally is indivisible, on function, refinforces each other, and is interactional on pathogenesis." element is asked. golden deficient the truth opinion " say: " the west redness of the skin or complexion goes into to lead in lung, has one's ideas straightened out in nose "; " element is asked. the five internal organs another matter " say: and " five gas are gone into nose, are hidden in cardiopulmonary, and cardiopulmonary are ill, and nose is also unfavorable for it." no matter explain that under physiology or pathologic condition, nose and cardiopulmonary are closely bound up.On the other hand, nose and brain are also closely related.Say like " skin infection book ": " nostril is the key of lung, leads in brain on its gas, and is descending in lung ".
Nose and whole body meridian also have very confidential relation.Meridians are passages of people's running body QI and blood, are to link up an inside and outside unique system up and down, belong to internal organs in it, and outer network is playing important effect in podomere aspect people's physiology, pathology and the disease preventing and treating.Nose is positioned at women's head-ornaments portion, and " all YANG-meridians meeting into the head ", all yang channels of whole body are all gone up in women's head-ornaments, and the yin channel of whole body is closed again in yang channel, and yang channel closes in herbal classic.In addition, the women's head-ornaments center is conception vessel and governor vessel boundary part just, and conception vessel is always appointed the yin channel of whole body, and the yang channel of governor vessel governor whole body is so nose also communicates with the whole body passages through which vital energy circulates.Said as Miraculous Pivot: " twelve regular channels, 365 networks, its QI and blood are all gone up from face and are walked the sky key ... be smelly from nose on its pectoral qi." unanswerable proof of clinical practice " the BITONG twelve regular channels and the vital organs of the human body " in several thousand years.And " passages through which vital energy circulates leads to, and cures mainly in one's power ".Therefore through the conduction and the Accommodation of meridians, nasal administration can be treated the various diseases of whole body.
Research now shows that though nasal cavity is little, the blood vessel under the bronchia mucosal is quite abundant, and numerous venule, tremulous pulse, blood capillary, lymphatic vessel are woven into net, extend in all direction.Particularly nasal membrane has many skies property characteristics, plays a part good to medicine to blood and tissue penetration.After medicine attaches to mucosa, be easy to see through mucosa and get into blood, and play a role through the circulation of normal pulse carotid artery entering systemic blood through intracranial very soon.Therefore nasal medication has better curative effect to the neoplastic hematologic disorder disease.In addition, on each cell of nose breathing district unnumbered fine hair is arranged, it is the same with intestinal villi to have very strong absorption function.The effective area of drug absorption is increased, and bioavailability increases thereupon, can better adjust the function balance of each tract of whole body, produces different pharmacological actions.So adopt the nasal cavity inhalation that many tumor patients are effectively treated.
Summary of the invention
One of the present invention aims to provide a kind of Chinese medicine ointment of treating tumor, it makes easily, easy to use, tumor is had definite curative effect reliably.
The present invention is used for tumor is implemented the Chinese medicine ointment of treatment; Used pharmacodynamic raw materials and weight proportion thereof are 0.2~1 part of Cordyceps, 0.001~0.005 part of arsenicum, 4~15 parts of Squama Manis, 8~23 of Scolopendras, 3~15 parts of Scorpios, 3~15 parts of Radix Salviae Miltiorrhizaes, 3~15 parts in Semen Persicae, 3~18 parts of Rhizoma Zingiberis Recens silkworms, 3~16 parts on Flos Carthami, 3~16 parts of Pseudobulbus Cremastrae seu Pleiones, 3~16 parts of Semen Sinapis Albaes, 3~16 parts of Cornu Bubali silks, 3~16 parts of Fructus Lycii, 3~16 parts in Radix Glycyrrhizae.
The optimum weight proportioning of the used pharmacodynamic raw materials of Chinese medicine ointment of the present invention does; The weight proportion of used pharmacodynamic raw materials is 0.5 part of Cordyceps, 0.003 part of arsenicum, 10 parts of Squama Manis, 15 of Scolopendras, 10 parts of Scorpios, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts in Semen Persicae, 10 parts of Rhizoma Zingiberis Recens silkworms, 10 parts on Flos Carthami, 10 parts of Pseudobulbus Cremastrae seu Pleiones, 10 parts of Semen Sinapis Albaes, 10 parts of Cornu Bubali silks, 10 parts of Fructus Lycii, 10 parts in Radix Glycyrrhizae.
Chinese medicine ointment of the present invention can also comprise Herba Alii fistulosi, Rhizoma Zingiberis Recens, Bulbus Allii on the basis of above solvent, be applicable to the bad person of taste.3~16 parts of Herba Alii fistulosis, 3~16 parts of Rhizoma Zingiberis Recens, 3~16 parts of weight portions of Bulbus Allii, optimum weight proportioning are 10 parts of Herba Alii fistulosis, 10 parts of Rhizoma Zingiberis Recens, 10 parts of Bulbus Alliis.
According to classic of TCM record and inventor observational study for many years, cancerous tissue also is the part of human body, and only at this imbalance between YIN and YANG of people, generation-inhibition in five elements is taken advantage of and insulted under the prerequisite that changes, and the immune monitoring system of human body just can lose monitoring to it, develops as one pleases.In the course of time, cancerous cell is bred day by day, and tumor troop grows stronger day by day, and corrodes normal surrounding tissue at last, consumes significant amount of energy and nutrition, influences the body normal physiological metabolism, causes body depleted gradually, finally causes death.
The present invention's two aims to provide the immunotherapy that a kind of Chinese medicine snuffing antiperspirant steams the treatment tumor; It is characterized in that; Its Therapeutic Method may further comprise the steps: A, get Cordyceps 1 gram, arsenicum 0.005 gram, Squama Manis 15 grams, 23 of Scolopendras, Scorpio 15 grams, Radix Salviae Miltiorrhizae 15 grams, Semen Persicae 15 grams, Rhizoma Zingiberis Recens silkworm 15 grams, Flos Carthami 16 grams, Pseudobulbus Cremastrae seu Pleiones 15 grams, Semen Sinapis Albae 15 grams, Cornu Bubali silk 15 grams, Fructus Lycii 15 grams, Radix Glycyrrhizae 15 grams, process Chinese medicine ointment; B, get two parts of Chinese medicine ointment and be divided into No. 1 bag and No. 2 bags, put into the medicine bottle of medicine absorber respectively, get the bag medicine absorber morning No. 2, suck through nasal cavity; Breathing out in the oral cavity, inhaled the morning medicine 3-4 hour, gets the bag medicine absorber afternoon No. 1; Nasal cavity is inhaled medicine and is got into the toxin expelling of perspiring in the sweat-steaming house after 2 hours, continues nasal cavity simultaneously and inhales medicine 1 hour, and drink the special-purpose drinking water of 100-250 milliliter; 3-4 month is a course of treatment, and the patient fully recovers and also took medication 45 days in back 1 year, in case recurrence.
The present invention sucks the medicine that tens flavor rare Chinese medicines are formed through nasal cavity, through mucosa absorption, make medicine directly act on human circulation blood, kills the cancerous cell in the blood; Excrete through the cancerous cell and the blood poison of perspire simultaneously apoptosis, the vicious cycle of avoiding the continuous operation of toxin to cause in vivo, thus reach thorough healing, prevent the purpose that recurs; Have the five internal organs of helping, beneficial vital essence, YIN nourishing is reinforced the kidney, the removing blood stasis with potent drugs knot; Remove the effect of heat in blood, it is few that the nasal-cavity administration therapy has dosage, and drug effect is fast, good absorbing; There are not liver and digestive tract first pass effect, advantage such as side effect is little, and is easy to use.
The specific embodiment
Below pharmaceutical composition of the present invention and formulation method are done further to detail through embodiment.
Embodiment processes Chinese medicine ointment
Get Cordyceps 1 gram, arsenicum 0.005 gram, Squama Manis 15 grams, 23 of Scolopendras, Scorpio 15 grams, Radix Salviae Miltiorrhizae 15 grams, Semen Persicae 15 grams, Rhizoma Zingiberis Recens silkworm 15 grams, Flos Carthami 16 grams, Pseudobulbus Cremastrae seu Pleiones 15 grams, Semen Sinapis Albae 15 grams, Cornu Bubali silk 15 grams, Fructus Lycii 15 grams, Radix Glycyrrhizae 15 grams, process Chinese medicine ointment.
Experimental example is used Drug therapy tumor 104 routine clinical efficacies of the present invention and is summed up
The inventor uses several 80 examples of Drug therapy tumor patient of the present invention in many decades, obtain good result.To select 104 complete routine final reports of term calendar year 2001 to 2008 interocclusal record following at present.
(1) physical data
This is organized in 104 examples, male 76 examples, women 28 examples; 9~76 years old age, The median age 51 years old; All cases all are diagnosed as tumor according to medical history, focal lesion characteristic, whole body performance, and 1 of the equal medication of all cases is more than the course of treatment, and treatment finishes the back and observes more than 3 months.Observe 3 months persons of less than after 1 course of treatment under medication, the drug withdrawal and do not include this group statistics in.This group 104 its Staging of course of disease of example and Clinical typing tabulation are as follows.
This group of table 1 104 routine tumor courses of disease distribute
The course of disease (moon) |
Total case |
~3 |
~5 |
~10 |
~20 |
~30 |
More than 30 |
Example |
104 |
18 |
20 |
32 |
20 |
10 |
4 |
Ratio (%) |
100 |
17.3 |
19.2 |
30.8 |
19.2 |
9.6 |
3.8 |
This group of table 2 104 routine clinical tumor typings
(2) Therapeutic Method
This group case gives the Chinese medicine ointment by the preparation of embodiment method.Get two parts of Chinese medicine ointment and be divided into No. 1 bag and No. 2 bags, put into the medicine bottle of medicine absorber respectively, get the bag medicine absorber morning No. 2, suck through nasal cavity; Breathing out in the oral cavity, inhaled the morning medicine 3-4 hour, gets the bag medicine absorber afternoon No. 1; Nasal cavity is inhaled medicine and is got into the toxin expelling of perspiring in the sweat-steaming house after 2 hours, continues nasal cavity simultaneously and inhales medicine 1 hour, and drink the special-purpose drinking water of 100-250 milliliter; 3-4 month is a course of treatment, and the patient fully recovers and also took medication 45 days in back 1 year, in case recurrence.
(3) therapeutic outcome
Curative effect judging standard:
Cure: focal lesion disappears fully, does not have pain, and follow-up observation does not have recurrence more than 3 months;
Produce effects: focal lesion 80% disappears, and idol has slight pain;
Take a turn for the better: focal lesion number of blocks and area reduce to some extent, but the amount that reduces does not reach 50% of the preceding focal lesion gross area of treatment, and the focus pain alleviates to some extent;
Invalid: focal lesion area and focus pain have no significant change before the treatment.
By above-mentioned curative effect judging standard, this is organized 104 routine oncologic application curative effect of medication of the present invention and analyzes like table 3.
The 104 routine tumor efficiency analyses of this group of table 3
The curative effect grade |
Total case |
Cure |
Produce effects |
Take a turn for the better |
Invalid |
Effective percentage |
Example |
104 |
83 |
11 |
5 |
5 |
99 |
Ratio (%) |
100 |
79.8 |
10.6 |
4.8 |
4.8 |
95.2 |
Table 3 shows that the effective percentage of the various tumor of Drug therapy of the present invention reaches 95.2%, and cure rate reaches 79.8%.Wherein healing person's 83 examples all are three courses of treatment of medication.