CN102579668B

CN102579668B - Chinese medicinal enema for treating infantile bacillary dysentery in clinical nursing

Info

Publication number: CN102579668B
Application number: CN2011104628482A
Authority: CN
Inventors: 邵常雪
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-12-31
Filing date: 2011-12-31
Publication date: 2013-07-17
Anticipated expiration: 2031-12-31
Also published as: CN102579668A

Abstract

The invention discloses a Chinese medicinal enema for treating infantile bacillary dysentery in clinical nursing. According to traditional Chinese medical science, bacillary dysentery is caused by catching pathogenic summer-heat and damp and pestilential pathogen or injury due to diet, and the pathogenetic characteristics of bacillary dysentery is presented with red-white purulent dysentery, abdominal pain, tenesmus and the like. A diagnostic remedy is adopted in traditional Chinese medical science, namely the treatment principle of clearing away heat, eliminating dampness, removing heat from blood and detoxicating is adopted. The Chinese medicinal enema is prepared by decocting cape jasmine fruit, ash bark, mongolian dandelion herb, common andrographis herb, purslane herb, rehmannia root, blackend swallowwort root, fennel fruit, green tangerine peel, combined spicebush root, cubeb and Chinese starjasmine stem in water. Clinical experiments prove that the total effective rate is 97.1 percent and is obvious superior to that of a control group, and particularly the average time of symptom disappearing is shorter than that of the symptom disappearing of the control group; and the Chinese medicinal enema is low in treatment cost and is worthy of popularizing and applying.

Description

A kind of clinical care herbal enema agent for the treatment of Pediatric bacterial dysentery

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of herbal enema agent for the treatment of Pediatric bacterial dysentery.

Background technology

Chronic bacillary dysentery is one of common intestinal infection disease of department of pediatrics, is infectious intestinal disease occurred frequently summer and autumn, and due to dysentery bacterium, diseased region is seen with rectum and sigmoid colon more.The prolonged and repeated diarrhoea of infant causes dehydration, nutrient malabsorption, thereby influences children's's growth promoter.The route of transmission mainly is by patient or bacillicarrier's feces and pollutes daily apparatus, tableware, toy for children, beverage etc. by the fly that carries disease germs and infect other people.The infant the lighter who suffers from bacillary dysentery is cardinal symptom to generate heat, suffer from abdominal pain, to have after an action of the bowels bearing down to reach with Mucous Stool or dense hemafecia often.Serious symptom person can happen suddenly hyperpyrexia, go into a coma, take out toxic encephalopthy symptoms such as convulsion, hypopnea, have in addition shock phenomenons such as pale complexion, cyanosis, cold limbs, pulse are thin and delicate can appear, send rescue to hospital as untimely, can cause life danger.

Owing to irregular medication, Resistant strain increases gradually in recent years, and quinolones and third generation cephamycin effect are more outstanding, but quinolones is influential to children's's cartilage development, and third generation cephamycin is expensive, must seek new antibacterials, selects new administering mode.

Summary of the invention

The purpose of this invention is to provide a kind of herbal enema agent for the treatment of Pediatric bacterial dysentery.The traditional Chinese medical science thinks that bacillary dysentery is owing to experience the heresy of heat-damp in summer epidemic disease poison, or injury due to diet and causing, and is pathogeneticing characteristic with the red white pus and blood of dysentery, stomachache, tenesmus etc.The traditional Chinese medical science is suited the remedy to the case, and is the rule for the treatment of with clearing away heat and eliminating dampness, removing pathogenic heat from blood and toxic substance from the body.

The objective of the invention is to be achieved through the following technical solutions, the herbal enema agent of this treatment Pediatric bacterial dysentery is made by following parts by weight of Chinese traditional medicine: Fructus Gardeniae 10-15 part, Cortex Fraxini 7-11 part, Herba Taraxaci 9-13 part, Herba Andrographis 7-9 part, Herba Portulacae 9-12 part, Radix Rehmanniae 9-15 part, Radix Cynanchi Atrati 7-10 part, Fructus Foeniculi 10-15 part, Pericarpium Citri Reticulatae Viride 9-13 part, Radix Linderae 7-9 part, Fructus Litseae 9-15 part, Caulis Trachelospermi 9-13 part.

Preferably, the herbal enema agent of this treatment Pediatric bacterial dysentery is made by following parts by weight of Chinese traditional medicine: 13 parts of Fructus Gardeniaes, 9 parts of Cortex Fraxinis, 11 parts of Herba Taraxacis, 8 parts of Herba Andrographis, 10 parts of Herba Portulacaes, 13 parts of Radix Rehmanniae, 9 parts of Radix Cynanchi Atratis, 13 parts of Fructus Foeniculi, 11 parts on Pericarpium Citri Reticulatae Viride, 8 parts of the Radixs Linderae, 12 parts of Fructus Litseae, 11 parts of Caulis Trachelospermis.

Above each medicine is made enema according to a conventional method.

Fructus Gardeniae pathogenic fire purging relieving restlessness in the side; Clearing away heat-damp and promoting diuresis; The removing pathogenic heat from blood and toxic substance from the body Fructus Gardeniae has inhibitory action, Cortex Fraxini heat clearing and damp drying, liver heat removing and eyesight improving, astringent therapy dysentery relieving to staphylococcus aureus, meningococcus, micrococcus catarrhalis etc.; The Herba Taraxaci heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Herba Taraxaci has stronger bactericidal action to staphylococcus aureus Resistant strain, Hemolytic streptococcus, and Diplococcus pneumoniae, meningococcus, diphtheria corynebacterium, bacillus pyocyaneus, Bacillus proteus, dysentery bacterium, Bacillus typhi etc. and micrococcus catarrhalis are also had certain bactericidal action; The Herba Andrographis heat-clearing and toxic substances removing, removing heat from blood, detumescence, dampness, heat-clearing and toxic substances removing, acute bacillary dysentery is controlled in the removing heat from blood detumescence; Effects such as Herba portulacae has heat-clearing and toxic substances removing, and it is treating stranguria to stop blooding.Radix Rehmanniae clearing away heat and promoting production of body fluid YIN nourishing nourishes blood; Radix Cynanchi Atrati clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome; Radix Linderae promoting the circulation of QI to relieve pain, warming kidney for dispelling cold; The Fructus Litseae warming the spleen and kidney, invigorating the stomach and promoting digestion; The Caulis Trachelospermi dispelling wind and removing obstruction in the collateral, the removing heat from blood detumescence.

Clinical data

1, physical data selected 128 routine cases are the acute bacillary dysentery infant that my institute is admitted to hospital from October, 2006～2008 year February.68 examples are organized in treatment, male 35 examples wherein, and women 33 examples, the age was from June～12 years old, average 5.5 years old; Matched group 60 examples, male 31 examples wherein, women 29 examples, the age was from July～11 years old, average 5 years old; Two groups of infants are at incidence, sex, age, the state of an illness etc. and treatment group no difference of science of statistics.

2, the whole cases of inclusion criteria all meet August nineteen ninety health ministry about " bacillary dysentery diagnostic criteria " (trying).

3, Therapeutic Method treatment group adopts enema retention enema of the present invention.Fang Xuan: Fructus Gardeniae 13g, Cortex Fraxini 9g, Herba Taraxaci 11g, Herba Andrographis 8g, Herba Portulacae 10g, Radix Rehmanniae 13g, Radix Cynanchi Atrati 9g, Fructus Foeniculi 13g, Pericarpium Citri Reticulatae Viride 11g, Radix Linderae 8g, Fructus Litseae 12g, Caulis Trachelospermi 11g.Place water purification to soak half an hour earlier, put into the 1000ml clear water and boil, change at a simmerly to 500ml, leave standstill its impurity, get supernatant 300ml, get 100ml at every turn, the deep retention enema was kept somewhere more than 1 hour at every turn, every day 3 times, 1 week of the course for the treatment of; Matched group is treated 1 week of the course for the treatment of with ampicillin 150mg/kg associating pipemidic acid sheet 40mg/kg.Nutritional support is given in two groups of Primary Cares, corrects water, electrolyte imbalance, and high hot person gives and bringing down a fever, and it is all identical that the violent person that suffers from abdominal pain gives relieving spasm to stop pain etc.

4, efficacy determination: cure: transference cure, the stool character recovers normal, and the drug withdrawal continuous culture of defecating after 3 days is negative for 3 times; Take a turn for the better: symptom takes a turn for the better, and stool is cultivated negative; Do not heal: symptom does not alleviate, and stool character and number of times do not have improvement, and cultivation is negative.

5, two groups of Comparison of therapeutic of therapeutic outcome: 68 examples are organized in treatment, cure 39 examples (59.1%), 27 examples that take a turn for the better (39.7%), 2 examples (2.9%) that do not heal, total effective rate 97.1%; Matched group 60 examples are cured 29 examples (48.3%), 22 examples that take a turn for the better (36.7%), 9 examples (15.0%) that do not heal, total effective rate 85.0%.Learn by statistics and handle, both have significant difference (P＜0.01).Two groups of transference cures compare average time: treatment group 2.5 days, and matched group 4.6 days, two groups have significant difference (P＜0.05).

The specific embodiment

Embodiment one: take by weighing Fructus Gardeniae 13g, Cortex Fraxini 9g, Herba Taraxaci 11g, Herba Andrographis 8g, Herba Portulacae 10g, Radix Rehmanniae 13g, Radix Cynanchi Atrati 9g, Fructus Foeniculi 13g, Pericarpium Citri Reticulatae Viride 11g, Radix Linderae 8g, Fructus Litseae 12g, Caulis Trachelospermi 11g.Place water purification to soak half an hour earlier, put into the 1000ml clear water and boil, change at a simmerly to 500ml, leave standstill its impurity, get supernatant 300ml, get 100ml at every turn, the deep retention enema was kept somewhere more than 1 hour at every turn, every day 3 times, 1 week of the course for the treatment of.

Embodiment two: take by weighing Fructus Gardeniae 15g, Cortex Fraxini 7g, Herba Taraxaci 9g, Herba Andrographis 7g, Herba Portulacae 12g, Radix Rehmanniae 9g, Radix Cynanchi Atrati 10g, Fructus Foeniculi 15g, Pericarpium Citri Reticulatae Viride 9g, Radix Linderae 7g, Fructus Litseae 15g, Caulis Trachelospermi 9g.Place water purification to soak half an hour earlier, put into the 900ml clear water and boil, change at a simmerly to 450ml, leave standstill its impurity, get supernatant 300ml, get 100ml at every turn, the deep retention enema was kept somewhere more than 1 hour at every turn, every day 3 times, 1 week of the course for the treatment of.

Embodiment three: take by weighing Fructus Gardeniae 10g, Cortex Fraxini 11g, Herba Taraxaci 13g, Herba Andrographis 9g, Herba Portulacae 9g, Radix Rehmanniae 15g, Radix Cynanchi Atrati 7g, Fructus Foeniculi 10g, Pericarpium Citri Reticulatae Viride 13g, Radix Linderae 9g, Fructus Litseae 9g, Caulis Trachelospermi 13g.Place water purification to soak half an hour earlier, put into the 950ml clear water and boil, change at a simmerly to 500ml, leave standstill its impurity, get supernatant 300ml, get 100ml at every turn, the deep retention enema was kept somewhere more than 1 hour at every turn, every day 3 times, 1 week of the course for the treatment of.

Claims

1. a clinical care is with the herbal enema agent for the treatment of Pediatric bacterial dysentery, it is characterized in that this herbal enema agent made by following parts by weight of Chinese traditional medicine: Fructus Gardeniae 13g, Cortex Fraxini 9g, Herba Taraxaci 11g, Herba Andrographis 8g, Herba Portulacae 10g, Radix Rehmanniae 13g, Radix Cynanchi Atrati 9g, Fructus Foeniculi 13g, Pericarpium Citri Reticulatae Viride 11g, Radix Linderae 8g, Fructus Litseae 12g, Caulis Trachelospermi 11g.