CN102578414B - Compound proplis feed additive capable of accelerating pig to grow and fatten and improving immunity and preparation method thereof - Google Patents

Compound proplis feed additive capable of accelerating pig to grow and fatten and improving immunity and preparation method thereof Download PDF

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Publication number
CN102578414B
CN102578414B CN201210041671.3A CN201210041671A CN102578414B CN 102578414 B CN102578414 B CN 102578414B CN 201210041671 A CN201210041671 A CN 201210041671A CN 102578414 B CN102578414 B CN 102578414B
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Prior art keywords
parts
feed additive
compound
proplis
preparation
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Expired - Fee Related
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CN201210041671.3A
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CN102578414A (en
Inventor
周庆福
刘文利
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Qingdao Lvman Bioengineering Co Ltd
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Qingdao Lvman Bioengineering Co Ltd
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Abstract

The invention discloses a compound proplis feed additive capable of accelerating pigs to grow and fatten and improving immunity and a preparation method thereof, belonging to the field of animal feed. The feed additive is prepared from the components in parts by weight: 15-45 parts of proplis, 10-30 parts of gynostemma pentaphylla, 15-45 parts of flower of poplar, 15-30 parts of echinacea purpurea, 15-35 parts of isomaltose hypgather and 10-20 parts of muramyl dipeptide. The compound proplis feed additive has the beneficial effects of reasonable formula and is simple to prepare. The compound does not have toxic and side effect, is free from pollution, is free from medicine residue, does not have medicine tolerance, is subjected to ultra-fine pulverization and has high bioavailability. After application, the compound proplis feed additive is proved to have special efficiency on accelerating pigs to grow and fatten and improving immunity.

Description

Promote the pig growing and fattening, improve compound bee-glue feed addictive of immunity and preparation method thereof
Technical field
The present invention relates to field of animal feed, particularly a kind of compound bee-glue green feed additive that is specifically designed to promotion pig growing and fattening, raising immunity and preparation method thereof.
Background technology
Piglet or growing-finishing pigs are slowly, hypoimmunity is relevant with many factors, and mainly relevant with weakness of the spleen and the stomach, the disease infection of pig etc., this disease all can occur throughout the year, is one of principal disease endangered pig industry.
Doctor trained in Western medicine prevents this disease mainly to take interpolation antimicrobial, vitamin, trace element etc. as main, and effect is not very desirable; And the traditional Chinese medical science thinks that this disease treatment should adopt the principle of beneficial gas stomach invigorating, raising immunity.
This disease almost spreads all over the world all livestock culturings country, is widely distributed.At present, treat this disease the most frequently used be Chinese medicine and Western medicine, Chinese medicine is because its prescription is unreasonable or simple pulverizing the just, particle diameter is excessive, medicine discharges slower, causes its bioavilability lower, clinical effectiveness is not fine; And in Western medicine, antimicrobial by force, easily produces the problems such as drug resistance and medicament residue due to its toxic and side effect, clinical practice is very limited.
Therefore researching and developing the having no side effect of compound bee-glue green feed additive, drug residue free, the specific medicament produced that has no drug resistance that a kind ofly promote the pig growing and fattening, improve immunity is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, ultramicro grinding, bioavilability are high, successful, have no side effect, have no drug resistance and effective promotion pig growing and fattening of medicament residue, improve compound bee-glue green feed additive of immunity and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of compound bee-glue green feed additive that promotes the pig growing and fattening, improves immunity, by following component by weight mixed preparing form: propolis 15-45 part, gynostemma pentaphylla 10-30 part, poplar flower 15-45 part, Echinacea 15-30 part, oligoisomaltose 15-35 part, muramyl dipeptide 10-20 part.
On the basis of such scheme, described various component optimum ratio amounts are: 30 parts of propolis, 20 parts of gynostemma pentaphylla, 30 parts of poplar flowers, 20 parts of Echinaceas, 25 parts of oligoisomaltoses, 15 parts of muramyl dipeptides.
A kind of preparation method who promotes the pig growing and fattening, improves the compound bee-glue green feed additive of immunity, carry out as follows:
(1) the various compositions in prescription are crossed to 700 mesh sieves after ultramicro grinding respectively;
(2) take by weight propolis 15-45 part, gynostemma pentaphylla 10-30 part, poplar flower 15-45 part, mix 5-10 minute to even;
(3) take by weight Echinacea 15-30 part, oligoisomaltose 15-35 part, muramyl dipeptide 10-20 part, mix 5-10 minute to even;
(4) merge the composition that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Propolis: bitter, acrid, cold, return spleen, lung, stomach warp, there is anti-bacteria and anti-virus, antalgesic-antipruritic, promotion regeneration, improve immunity, antiallergy oxidation, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa etc.
Gynostemma pentaphylla: distinguish the flavor of sweet, bitter, cold nature, return spleen, lung, kidney channel, there is benefiting qi for tranquillization, clearing heat and detoxicating, cough-relieving apophlegmatic, anti-inflammatory step-down, improve the function of immunity etc.
Poplar flower: bitter, cold, return liver, courage, large intestine channel, there is function clearing heat and detoxicating, dampness elimination antidiarrheal; Cure mainly damp-heat diarrhea, cub is had loose bowels etc.
Echinacea: main active is polyphenol, and caffeic acid derivative and polysaccharide etc. have and improve immunity, accelerate that tissue upgrades and the anti-infectious function such as antibiotic, antiviral.
Oligoisomaltose: be the compound sugar that glucose molecule connects with 1.4 glycosidic bonds, it can effectively promote the growth and breeding of beneficial bacteria-Bifidobacterium in human body, therefore be called again " positive growth factor for bifidus ", is called for short " Oilgosaccharkdes ".There is activated lymphocyte, promote the immune response of body, strengthen and the adjusting humoral immunity, strengthen generation and the reactivity of interleukins (IL-1, IL-2), improve peripheral white blood cell, improve the various biological functions such as resisting stress capability and anti-inflammatory, improve the resistance of body to various diseases, and can promote absorption and the utilization of animal to nutriment.Can be used for treating various illnesss that immunity function lowly causes, can treat repeated infection that various virus, pathogenic bacteria etc. cause etc.
Muramyl dipeptide: be the minimal structure unit that there is the immunologic adjuvant activity in the mycobacterium cytoskeleton, it has adjuvant effect, but the immunogen activity of enhancement antigen, stimulating expression of macrophage, promote lymphokine to discharge, promote bone-marrow-derived lymphocyte and the lymphocytic function of T.It can provide liver, the abundant nutrition of kidney, promote liver production albumen and immune protein to synthesize to have significantly and protect the liver, protect kidney, function of invigorating spleen by improving microcirculation decorporation toxin.And itself has the function of digestive ferment, can promote gastro-intestinal digestion, improve stomach power, in can also promoting when increasing exogenous digestive ferment, in the secretion of digestive ferment, promote to digest.Also can improve the balance of gut flora, promote the growth of the profitable strains such as Bifidobacterium Bifidum, lactic acid bacteria etc.
Above all herbal medicine compatibility combinations, for the various factors that affects pig growing and fattening and hypoimmunity, the effect that performance is treated both principal and secondary aspect of disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Chinese medicine composition is pollution-free, have no side effect, no drug residue, have no drug resistance, and cost is low, draws materials wide, and ultramicro grinding, bioavilability are high, the curative effect highly significant.Application attestation, to promoting the pig growing and fattening, improve immunity special efficacy is arranged, and make its product meat reach nuisanceless requirement, meets the export standard of product, effectively guaranteed that people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:
Embodiment 1
A kind of compound bee-glue green feed additive that promotes pig growing and fattening, raising immunity and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after ultramicro grinding respectively;
(2) take by weight 150 parts of propolis, 100 parts of gynostemma pentaphylla, 150 parts of poplar flowers, mix 5-10 minute to even;
(3) take by weight 150 parts of Echinaceas, 150 parts of oligoisomaltoses, 100 parts of muramyl dipeptides, mix 5-10 minute to even;
(4) merge the composition that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of compound bee-glue green feed additive that promotes pig growing and fattening, raising immunity and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after ultramicro grinding respectively;
(2) take by weight 300 parts of propolis, 200 parts of gynostemma pentaphylla, 300 parts of poplar flowers, mix 5-10 minute to even;
(3) take by weight 250 parts of Echinaceas, 250 parts of oligoisomaltoses, 150 parts of muramyl dipeptides, mix 5-10 minute to even;
(4) merge the composition that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of compound bee-glue green feed additive that promotes pig growing and fattening, raising immunity and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are crossed to 700 mesh sieves after ultramicro grinding respectively;
(2) take by weight 450 parts of propolis, 300 parts of gynostemma pentaphylla, 450 parts of poplar flowers, mix 5-10 minute to even;
(3) take by weight 300 parts of Echinaceas, 350 parts of oligoisomaltoses, 200 parts of muramyl dipeptides, mix 5-10 minute to even;
(4) merge the composition that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical testing:
Product day of the present invention, dose was: every 100g spice 1000kg feeds, every day 1-2 time.
Table is field application (30 days experimental periods) situation contrast that the present invention and other medicines promote the pig growing and fattening:
Numbering Group Average just starting weight (kg) Rate of body weight gain % The average whole story heavy (kg)
I The blank group 13.6 16.2 15.8
II The powder for improving appetite group 13.9 25.2 17.4
III Of the present invention group 13.5 39.3 18.8
This clinical effectiveness statistical analysis, comparing difference extremely significantly (P<0.01) with the powder for improving appetite group for of the present invention group aspect rate of body weight gain.
Above-mentioned detailed description of this promotion pig growing and fattening, the compound bee-glue green feed additive and preparation method thereof that improves immunity being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under general plotting of the present invention, within should belonging to protection scope of the present invention.

Claims (1)

1. a porcine compound propolis green feed additive, it is characterized in that by following component by weight mixed preparing form: 30 parts of propolis, 20 parts of gynostemma pentaphylla, 30 parts of poplar flowers, 20 parts of Echinaceas, 25 parts of oligoisomaltoses, 15 parts of muramyl dipeptides.
CN201210041671.3A 2012-02-23 2012-02-23 Compound proplis feed additive capable of accelerating pig to grow and fatten and improving immunity and preparation method thereof Expired - Fee Related CN102578414B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3474894A4 (en) * 2016-06-23 2020-02-19 Nutrivert LLC Methods to promote growth and improve feed conversion in animals

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103636945A (en) * 2013-12-06 2014-03-19 江苏威泰龙生物科技有限公司 Compound type biological active peptide product for livestock and poultry and application thereof
CN109497260A (en) * 2018-11-13 2019-03-22 南宁学院 A kind of health care Chinese medicine dreg fodder additive and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1887109A (en) * 2006-07-21 2007-01-03 叶庆丰 Propolis health food and its prepn
RU2353376C1 (en) * 2007-08-10 2009-04-27 Федеральное государственное образовательное учреждение высшего профессионального образования Кубанский государственный аграрный университет Method of bronchial pneumonia treatment and prevention in calves and piglets
CN101822734A (en) * 2009-03-04 2010-09-08 北京因科瑞斯医药科技有限公司 Chinese medicinal composition with function of deferring senility and preparation method thereof
CN102091321A (en) * 2009-12-15 2011-06-15 天津中敖生物科技有限公司 Medicament oral liquid for treating enteritis and diarrhea and preparation method thereof
CN102319288A (en) * 2011-08-31 2012-01-18 青岛绿曼生物工程有限公司 Pure traditional Chinese medicine composition for treating poultry infectious bursal disease and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1887109A (en) * 2006-07-21 2007-01-03 叶庆丰 Propolis health food and its prepn
RU2353376C1 (en) * 2007-08-10 2009-04-27 Федеральное государственное образовательное учреждение высшего профессионального образования Кубанский государственный аграрный университет Method of bronchial pneumonia treatment and prevention in calves and piglets
CN101822734A (en) * 2009-03-04 2010-09-08 北京因科瑞斯医药科技有限公司 Chinese medicinal composition with function of deferring senility and preparation method thereof
CN102091321A (en) * 2009-12-15 2011-06-15 天津中敖生物科技有限公司 Medicament oral liquid for treating enteritis and diarrhea and preparation method thereof
CN102319288A (en) * 2011-08-31 2012-01-18 青岛绿曼生物工程有限公司 Pure traditional Chinese medicine composition for treating poultry infectious bursal disease and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3474894A4 (en) * 2016-06-23 2020-02-19 Nutrivert LLC Methods to promote growth and improve feed conversion in animals

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