CN102574893A - 新的抗致病肽 - Google Patents

新的抗致病肽 Download PDF

Info

Publication number
CN102574893A
CN102574893A CN2010800283316A CN201080028331A CN102574893A CN 102574893 A CN102574893 A CN 102574893A CN 2010800283316 A CN2010800283316 A CN 2010800283316A CN 201080028331 A CN201080028331 A CN 201080028331A CN 102574893 A CN102574893 A CN 102574893A
Authority
CN
China
Prior art keywords
amino acid
carbon atoms
compound
side chain
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800283316A
Other languages
English (en)
Chinese (zh)
Inventor
A·吉尔勒尼
G·皮里
L·皮佐图
S·兰多尔弗
G·格里鲍多
D·勒姆伯
D·吉贝尔里尼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spiderbiotech S R L
Original Assignee
Spiderbiotech S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spiderbiotech S R L filed Critical Spiderbiotech S R L
Publication of CN102574893A publication Critical patent/CN102574893A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN2010800283316A 2009-08-05 2010-08-05 新的抗致病肽 Pending CN102574893A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2009A001425A IT1395137B1 (it) 2009-08-05 2009-08-05 Nuovi peptidi antipatogeni
ITMI2009A001425 2009-08-05
PCT/EP2010/061424 WO2011015628A1 (en) 2009-08-05 2010-08-05 Novel antipathogenic peptides

Publications (1)

Publication Number Publication Date
CN102574893A true CN102574893A (zh) 2012-07-11

Family

ID=42046263

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800283316A Pending CN102574893A (zh) 2009-08-05 2010-08-05 新的抗致病肽

Country Status (8)

Country Link
US (1) US8877738B2 (enExample)
EP (1) EP2462155B1 (enExample)
JP (1) JP2013501030A (enExample)
CN (1) CN102574893A (enExample)
AU (1) AU2010280682A1 (enExample)
CA (1) CA2768748A1 (enExample)
IT (1) IT1395137B1 (enExample)
WO (1) WO2011015628A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2803354B1 (de) 2013-05-14 2015-03-04 NajöPharm GmbH i.G. Kombination aus Polyacrylsäure und 2-Amino-2-methylpropanol zur Verwendung in der Behandlung von Herpesinfektionen
US10702572B2 (en) * 2015-07-28 2020-07-07 Carnegie Mellon University Methods and compounds to suppress viral genome release and packaging
RU2655763C2 (ru) * 2016-10-24 2018-05-29 Общество С Ограниченной Ответственностью "Айвикс" Фармацевтическая композиция и способ лечения женских сексуальных дисфункций
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria
CN120349386B (zh) * 2025-04-29 2025-11-28 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 人工合成多肽p2及其在抗疱疹病毒感染中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL131368A0 (en) * 1997-02-20 2001-01-28 Yeda Res & Dev Antipathogenic synthetic peptides and compositions comprising them
US6660843B1 (en) * 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
US20090087878A9 (en) * 1999-05-06 2009-04-02 La Rosa Thomas J Nucleic acid molecules associated with plants
AUPR412801A0 (en) 2001-03-30 2001-05-03 Starpharma Limited Agent for the prevention and treatment of sexually transmitted disease s - I
AU2003222069A1 (en) * 2002-03-29 2003-10-20 Centocor, Inc. Mammalian cdr mimetibodies, compositions, methods and uses
ES2323178T3 (es) * 2003-09-30 2009-07-08 Janssen Pharmaceutica Nv Compuestos de benzoimidazol.
US20060127404A1 (en) * 2003-09-30 2006-06-15 Chichi Huang Hinge core mimetibodies, compositions, methods and uses
JP2008505928A (ja) * 2004-07-08 2008-02-28 アムジェン　インコーポレーテッド 治療用ペプチド
DK1778271T3 (da) 2004-08-18 2009-02-16 Ipf Pharmaceuticals Gmbh Peptid til behandling af herpesvirusinfektioner
CA2660668C (en) * 2006-08-21 2016-06-28 The University Of British Columbia Small cationic antimicrobial peptides
US20110171233A1 (en) * 2007-08-22 2011-07-14 Ribovax Biotechnologies S.A. Antibodies Against Human Cytomegalovirus (HCMV)

Also Published As

Publication number Publication date
ITMI20091425A1 (it) 2011-02-06
US20120121623A1 (en) 2012-05-17
JP2013501030A (ja) 2013-01-10
EP2462155A1 (en) 2012-06-13
WO2011015628A1 (en) 2011-02-10
EP2462155B1 (en) 2015-05-27
AU2010280682A1 (en) 2012-01-19
CA2768748A1 (en) 2011-02-10
US8877738B2 (en) 2014-11-04
IT1395137B1 (it) 2012-09-05

Similar Documents

Publication Publication Date Title
US8748566B2 (en) Pharmacologically active antiviral peptides and methods of use
CN103429621B (zh) 抗微生物融合化合物及其用途
Röcker et al. Structure, function and antagonism of semen amyloids
WO2022256024A1 (en) Compositions and methods for treating sars-cov-2 infections
CN102574893A (zh) 新的抗致病肽
JP2016539922A (ja) 細胞透過性αヘリックスペプチド多量体、これの製造方法およびその用途
Hong et al. Design of histidine-rich peptides with enhanced bioavailability and inhibitory activity against hepatitis C virus
WO2024217209A1 (zh) 冠状病毒多肽类融合抑制剂的长效化的方法
EP2571524B1 (en) Anti-viral agents and compositions thereof
Chung et al. Preventive and therapeutic effects of a super-multivalent sialylated filamentous bacteriophage against the influenza virus
US7432045B2 (en) Method of inhibiting influenza infection with antiviral peptides
US8840875B2 (en) Anti-viral agents and compositions thereof
CN102596222B (zh) 作为肿瘤生长的抑制剂的皮抑菌肽b2
CN103709232B (zh) 一种抑制艾滋病病毒感染活性的多肽及其相关噬菌体
JP2020528072A (ja) ペプチドおよび抗ウイルス剤としてのその使用
CN101495505A (zh) 被膦酸酯或膦酸取代的手性化合物
WO2019032726A1 (en) METHODS OF TREATMENT AND PREVENTION OF VIRAL INFECTIONS
JP2020059662A (ja) 抗ウイルス性ペプチドおよびその利用
AU2006202024B2 (en) Pharmacologically active antiviral peptides and methods of their use
WO2023208812A1 (en) Novel antiviral compounds and use thereof
EP1862471A2 (en) Pharmacologically active antiviral peptides and methods of their use
WO2013023166A2 (en) Hapivirins and diprovirins

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20120711