CN102552091A - Liquid eyeliner with effect of promoting eyelash growth - Google Patents
Liquid eyeliner with effect of promoting eyelash growth Download PDFInfo
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- CN102552091A CN102552091A CN2012100274002A CN201210027400A CN102552091A CN 102552091 A CN102552091 A CN 102552091A CN 2012100274002 A CN2012100274002 A CN 2012100274002A CN 201210027400 A CN201210027400 A CN 201210027400A CN 102552091 A CN102552091 A CN 102552091A
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Abstract
The invention discloses a liquid eyeliner with an effect of promoting eyelash growth, comprising the following components: (1) cell growth factor components such as an acid or basic fibroblast growth factor, a dual-directional regulation growth promoting factor and an insulin-like growth factor; (2) a component for dilating the vessel such as Codariocalyx motorius saponin extract; (3) components for promoting the drug absorption such as propylene glycol, azone and menthol; (4) a component for regulating the acid-base balance; (5) bacterial growth inhibitor; and (6) the balance of deionized water. The liquid eyeliner is obtained through dissolving or mixing the above components in the deionized water and uniformly stirring. The liquid eyeliner disclosed by the invention has the advantages that the effect of promoting the eyelash growth is very obvious; the effect is very satisfying through wide trial because the eyelash growth can be seen in two weeks and the length, the thickness and the density can grow by about 1 time in four months; the growth effect is more satisfying to patients who have sparse eyelashes or lose eyelashes because of eyelash grafting; and certain effect on promoting the eyebrow growth is further provided.
Description
Technical field
The present invention relates to a kind of liquid that promotes human hair growth, especially have the eye-liner that promotes eyelashes growth effect.
Background technology
Long eyelashes have the effect that beautifies expansion human body eye, increase the third dimension of eyes, promote the view effect of human body face to a great extent; For this reason, people usually use mascara in cosmetic, and in mascara, add fiber, and fiber is stained with on the original eyelashes, make eyelashes seem than originally more slightly, longer.The black eye-liner also has similar effect, makes eyelashes seem denser.But these cosmetic methods are not long-term plans, and must cosmetic every day just such effect can be arranged, and this not only has damage to eyelashes, and has wasted the great amount of time cosmetic, the makeup removing of also will taking time, very trouble.For the people that can not use mascara to make up, bother more simultaneously, best method is to make eyelashes oneself long, long slightly, long close, forms natural length, thick, close eyelashes, plays the view effect effect that nature promotes human body face.But up to the present, there is not a real eye-liner that can make the eyelashes growth,
We know that eyelashes are a kind of of chaeta, and the growth cycle of hair is divided into three phases: from the growth (being active phase) through catagen excessively to resting stage.Complex interactions is relevant between the growth cycle of control hair and mao protruding and two tissues of hair papilla.Owing to contain the neural blood supply that nutrition is provided to hair that reaches in the hair papilla, therefore the protruding cell that has the whole hair follicle of regenerating of hair is the basic of hair growth.Hair is to grow from hair follicle, and hair follicle and hair all are by ball top bottom hair matrix cell differentiation.A hair follicle picture elongated pocket, corium and subcutaneous layer of fat are goed deep in the surface of opening and skin, bottom.Hair follicle is divided into three layers of inside and outside hair root sheath and connective tissue sheaths from inside to outside again, and inside and outside hair root sheath originates from epidermis, and connective tissue sheath originates from corium.Hair exposes skin surface and partly is hair shaft, is in hair follicle inside and is divided into Rhizoma Imperatae.The Rhizoma Imperatae lower end is expanded and is claimed ball top like Bulbus Allii Cepae, and the ball top basilar part caves inward and is hair papilla.The part that ball top lower floor and hair papilla are relative is a hair matrix, is the vitellarium of hair and hair follicle, and melanocyte is wherein arranged.Abundant blood vessel and nerve are arranged, with the nutrition and the growth of supply hair in the hair papilla.
The eyelashes position is very special, is positioned at the edge of eyes, so the eyelashes growth-promoting media not only requires skin is not stimulated, and can not injury effect be arranged to eyes simultaneously,
Summary of the invention
The present invention is directed to the eye-liner that do not have really to make the eyelashes growth in existing, make up to eyelashes damage is arranged, making up has wasted great amount of time, unusual deficiency such as trouble, and a kind of eye-liner with promotion eyelashes growth effect is provided.Have the effect of the eyelash growing of promotion, make eyelashes oneself long, long thick, long close, simultaneously can be easy to use as eye-liner, and cosmetic effect is arranged.
Technical scheme of the present invention: have the eye-liner that promotes eyelashes growth effect, it is characterized in that comprising following constituent:
(1) cell growth factor component: acid fibroblast growth factor, mass percent are 0.001-1%; Two-ways regulation somatomedin, mass percent are 0.001-1%; Insulin like growth factor, mass percent are 0.001-1%; Be among aforementioned three kinds of materials any, or any two, wantonly three kinds mixture;
Or basic fibroblast growth factor, mass percent is 0.001-1%; The two-ways regulation growth promotion because of
Son, mass percent are 0.001-1%; Insulin like growth factor, mass percent are 0.001-1%; Be among aforementioned three kinds of materials any, or any two mixture;
(2) component of blood vessel dilating; The careless Saponin class extract of dancing, mass percent is 5-20%;
Or in the nifedipine, diltiazem, phentolamine, prazosin, Phenoxybenzamine, nitroglycerin, nicotinic acid
Any, mass percent is 5-20%;
(3) promote the drug absorption component: propylene glycol, mass percent are 1-10%; Azone, mass percent are 0.5-5%, menthol, and mass percent is 0.1-2%; Among aforementioned three kinds of materials any, or any two mixture;
(4) component of adjustment acid-base balance: hydrophosphate solution, triethanolamine solution, Pehanorm solution, bicarbonate solution, citrate solution, acetate solution, barbiturates saline solution, mass percent is 1%-10%; Among aforementioned seven kinds of materials any;
(5) prevent the bacterial growth agent: methyl hydroxybenzoate, ethyl hydroxybenzoate, potassium sorbate, bromo geramine, sodium dehydroacetate, mass percent 0.1-2%; Among aforementioned five kinds of materials any, or any two mixture;
(6) surplus is a deionized water; Aforementioned component is dissolved or mixed in the deionized water, stirs.
Further characteristic is: also comprise the helper component pigment, mass percent 1-15%.
Also comprise the helper component film former, mass percent 0.5-5%.
Also comprise the helper component volatilizer, mass percent 1-10%.
Also comprise the helper component emulsifying agent, mass percent 0.5-5%.
The present invention has the eye-liner that promotes eyelashes growth effect, with respect to prior art, has following characteristics:
1, promotes that the eyelash growing effect is very obvious; On probation through extensively, effect is very satisfied, can see the eyelashes growth after 2 weeks, can length after April, thickness, density can grow into about original 1 times.
2, for the rare patient of eyelashes, perhaps because use grafting eyelashes cause deplumation, it is more satisfied to increase effect.
3, can be easy to use as eye-liner, and cosmetic effect is arranged.
4, to promoting the eyebrow growth that certain effect is also arranged.
The specific embodiment
The present invention has the eye-liner that promotes eyelashes growth effect, and it comprises following main component:
1, cell growth factor component: acid fibroblast growth factor (aFGF), mass percent are 0.001-1%; Two-ways regulation somatomedin (RGF), mass percent are 0.001-1%; Insulin like growth factor (IGF) mass percent is 0.001-1%; Be among aforementioned three kinds of materials any, or any two, wantonly three kinds mixture;
Or basic fibroblast growth factor (aFGF), mass percent is 0.001-1%; Two-ways regulation
Somatomedin (RGF), mass percent are 0.001-1%; Insulin like growth factor (IGF) mass percent is 0.001-1%; Be among aforementioned three kinds of materials any, or any two, wantonly three kinds mixture;
2, the component of blood vessel dilating; The careless Saponin class extract of dancing, mass percent is 5-20%;
Or in the nifedipine, diltiazem, phentolamine, prazosin, Phenoxybenzamine, nitroglycerin, nicotinic acid
Any, mass percent is 5-20%;
3, promote the drug absorption component: propylene glycol, mass percent are 1-10%; Azone, mass percent are 0.5-5%, menthol, and mass percent is 0.1-2%; Among aforementioned three kinds of materials any, or any two mixture;
4, the component of adjustment acid-base balance: hydrophosphate solution, triethanolamine solution, Pehanorm solution, bicarbonate solution, citrate solution, acetate solution, barbiturates saline solution, mass percent 1%-10%; Among aforementioned seven kinds of materials any; According to the needs of reality adjustment pH value, can behind acid overrich (pH value is low), add the saline solution of alkalescence, with the rising pH value to reach requirement; Equally, (pH value is high) adds tart saline solution, to reduce high pH value to reach requirement behind alkaline overrich;
5, prevent the bacterial growth agent: methyl hydroxybenzoate, ethyl hydroxybenzoate, potassium sorbate, bromo geramine, sodium dehydroacetate, mass percent all is 0.1-2%; Among aforementioned five kinds of materials any, or any two mixture; Certainly under situation about not reacting, can be two or more, mix mutually until whole five kinds;
6, surplus is a deionized water; Aforementioned component is dissolved or mixed in the deionized water, stirs;
Can also comprise (interpolation) helper component as the case may be: pigment (like iron oxide black, iron oxide red etc.), mass percent 1-15%; Film former, mass percent 0.5-5%; Volatilizer, mass percent 1-10%; Emulsifying agent, mass percent 0.5-5%; The mixture of any among aforementioned four kinds of materials or two kinds, three kinds, four kinds.Pigment, film former, volatilizer, emulsifying agent etc. are all selected the suitable medical material of prior art for use, do not detail at this.
The effect of cell growth factor is to promote hair follicle growth; The careless extract effect of dancing is to promote the hair follicle peripheral vasodilation; Also can use other vasodilation medicines to replace, like nifedipine, diltiazem, phentolamine, prazosin, Phenoxybenzamine, nitroglycerin, nicotinic acid etc.; Propylene glycol, azone, the effect of menthol is a Transdermal absorption, is that said medicine can arrive medicine hair follicle root, prevents that the bacterial growth agent from being in order to guarantee that informer's fluid power preserves for a long time, to be difficult for by germ contamination.Pigment has cosmetic effect, and film former guarantees that eye-liner keeps the long period on skin, is unlikelyly washed off easily, and volatilizer guarantees that eye-liner is dry rapidly, can not flow in the eyes, also is difficult for other places of making dirty.Emulsifying agent guarantees that eye-liner does not evenly precipitate.The effect of component of adjustment acid-base balance is to regulate the eye-liner acid-base balance, makes the ph value stabilization in technological requirement in normal range.
Embodiment 1: acid fibroblast growth factor aFGF 0.01%, two-ways regulation somatomedin RGF concentration (0.02%), the careless extract (10%) of dancing; Potassium phosphate buffer 5%, methyl hydroxybenzoate 0.5%, ethyl hydroxybenzoate 0.5%; As the volatile silicone oils 5% of volatilizer, be 2% as the sorbester p18 content of emulsifying agent, water solublity azone 1%; Propylene glycol 2%, carboxymethyl cellulose 2%, above-mentioned substance are dissolved in the deionized water respectively; Add 5% iron oxide black at last, stir at normal temperatures, and pH value is remained in the 6.5-7.2 scope promptly get.
Embodiment 2, basic fibroblast growth factor aFGF 0.01%, two-ways regulation somatomedin RGF concentration (0.02%); Insulin-like growth factor I GF (0.01%), triethanolamine buffer solution 4%, the careless extract (15%) of dancing; Hydroxyethyl-cellulose 3% is as the bromo geramine 0.1% of antiseptic, propylene glycol 2%; Azone 0.5%, menthol 1% is as the content 2% of the polysorbate40 of emulsifying agent; Above-mentioned substance is dissolved in respectively in the deionized water, adds 10% iron oxide black at last, stirs at normal temperatures, makes pH value remain in the 7-7.4 scope, promptly gets, and above-mentioned two embodiment also can not add pigment pigment, is fit to night or man and uses.
Method for using in the eye-liner pen, is applied to the eyelashes root with above-mentioned eye-liner fill, treats to dry in 1-2 minute to get final product.Mainly try not to flow in the eyes,, use the clear water flush away immediately if take place.Scribble 1-2 every day,
On probation through extensively; Effect is very satisfied, can see eyelashes growths after 2 weeks, can length after April, thickness, density can grow into about original 1 times; Rare for eyelashes; Perhaps because use grafting eyelashes cause deplumation, it is more satisfied to increase effect, is used on the eyebrow also to produce effect.
Claims (7)
1. have the eye-liner that promotes eyelashes growth effect, it is characterized in that comprising following constituent:
(1) cell growth factor component: acid fibroblast growth factor, mass percent are 0.001-1%; Two-ways regulation somatomedin, mass percent are 0.001-1%; Insulin like growth factor, mass percent are 0.001-1%; Be among aforementioned three kinds of materials any, or any two, three kinds mixture;
Or basic fibroblast growth factor, mass percent is 0.001-1%; The two-ways regulation growth promotion because of
Son, mass percent are 0.001-1%; Insulin like growth factor, mass percent are 0.001-1%; Be among aforementioned three kinds of materials any, or any two, three kinds mixture;
(2) component of blood vessel dilating; The careless Saponin class extract of dancing, mass percent is 5-20%;
Or in the nifedipine, diltiazem, phentolamine, prazosin, Phenoxybenzamine, nitroglycerin, nicotinic acid
Any, mass percent is 5-20%;
(3) promote the drug absorption component: propylene glycol, mass percent are 1-10%; Azone, mass percent are 0.5-5%, menthol, and mass percent is 0.1-2%; Among aforementioned three kinds of materials any, or any two mixture;
(4) component of adjustment acid-base balance: hydrophosphate solution, triethanolamine solution, Pehanorm solution, bicarbonate solution, citrate solution, acetate solution, barbiturates saline solution, mass percent is 1%-10%; Among aforementioned seven kinds of materials any;
(5) prevent the bacterial growth agent: methyl hydroxybenzoate, ethyl hydroxybenzoate, potassium sorbate, bromo geramine, sodium dehydroacetate, mass percent 0.1-2%; Among aforementioned five kinds of materials any, or any two mixture;
(6) surplus is a deionized water; Aforementioned component is dissolved or mixed in the deionized water, stirs.
2. according to the said eye-liner of claim 1, it is characterized in that: also comprise the helper component pigment, mass percent 1-15% with promotion eyelashes growth effect.
3. according to claim 1 or 2 said eye-liner, it is characterized in that: also comprise the helper component film former, mass percent 0.5-5% with promotion eyelashes growth effect.
4. according to claim 1 or 2 said eye-liner, it is characterized in that: also comprise the helper component volatilizer, mass percent 1-10% with promotion eyelashes growth effect.
5. according to claim 1 or 2 said eye-liner, it is characterized in that: also comprise the helper component emulsifying agent, mass percent 0.5-5% with promotion eyelashes growth effect.
6. according to the said eye-liner of claim 3, it is characterized in that: also comprise the helper component volatilizer, mass percent 1-10% with promotion eyelashes growth effect.
7. according to the said eye-liner of claim 6, it is characterized in that: also comprise the helper component emulsifying agent, mass percent 0.5-5% with promotion eyelashes growth effect.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100274002A CN102552091A (en) | 2012-02-08 | 2012-02-08 | Liquid eyeliner with effect of promoting eyelash growth |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100274002A CN102552091A (en) | 2012-02-08 | 2012-02-08 | Liquid eyeliner with effect of promoting eyelash growth |
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| CN102552091A true CN102552091A (en) | 2012-07-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2012100274002A Pending CN102552091A (en) | 2012-02-08 | 2012-02-08 | Liquid eyeliner with effect of promoting eyelash growth |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074201A (en) * | 2016-08-29 | 2016-11-09 | 何元凤 | A kind of eyebrow tattooing dye liquor and preparation method |
| CN106466505A (en) * | 2015-08-17 | 2017-03-01 | 陈丽娟 | Allow eyebrow renovation process in a short time |
| CN106963673A (en) * | 2017-02-16 | 2017-07-21 | 玉林祺钟商贸有限公司 | A kind of mascara solution and preparation method thereof |
| WO2020015377A1 (en) * | 2018-07-18 | 2020-01-23 | 温州医科大学 | Method for treating myopia and application thereof in preparing drug |
| CN111467264A (en) * | 2020-05-16 | 2020-07-31 | 青岛爱蕾诗假睫毛有限公司 | Eyelash eyeliner |
| CN112315879A (en) * | 2020-11-13 | 2021-02-05 | 罗彬相 | Biological factor eyelash nourishing liquid and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1160582A (en) * | 1996-12-27 | 1997-10-01 | 暨南大学生物工程研究所 | External-use composite containing cell growth factor |
-
2012
- 2012-02-08 CN CN2012100274002A patent/CN102552091A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1160582A (en) * | 1996-12-27 | 1997-10-01 | 暨南大学生物工程研究所 | External-use composite containing cell growth factor |
Non-Patent Citations (1)
| Title |
|---|
| 王勇等: "舞草的化学成分", 《中国天然药物》, vol. 5, no. 5, 30 September 2007 (2007-09-30), pages 357 - 359 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106466505A (en) * | 2015-08-17 | 2017-03-01 | 陈丽娟 | Allow eyebrow renovation process in a short time |
| CN106074201A (en) * | 2016-08-29 | 2016-11-09 | 何元凤 | A kind of eyebrow tattooing dye liquor and preparation method |
| CN106074201B (en) * | 2016-08-29 | 2019-01-22 | 何元凤 | A kind of eyebrow tattooing dye liquor and preparation method |
| CN106963673A (en) * | 2017-02-16 | 2017-07-21 | 玉林祺钟商贸有限公司 | A kind of mascara solution and preparation method thereof |
| WO2020015377A1 (en) * | 2018-07-18 | 2020-01-23 | 温州医科大学 | Method for treating myopia and application thereof in preparing drug |
| CN111467264A (en) * | 2020-05-16 | 2020-07-31 | 青岛爱蕾诗假睫毛有限公司 | Eyelash eyeliner |
| CN112315879A (en) * | 2020-11-13 | 2021-02-05 | 罗彬相 | Biological factor eyelash nourishing liquid and preparation method thereof |
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Application publication date: 20120711 |