CN102549430A - 表征细胞重编程的方法及其应用 - Google Patents
表征细胞重编程的方法及其应用 Download PDFInfo
- Publication number
- CN102549430A CN102549430A CN2010800430122A CN201080043012A CN102549430A CN 102549430 A CN102549430 A CN 102549430A CN 2010800430122 A CN2010800430122 A CN 2010800430122A CN 201080043012 A CN201080043012 A CN 201080043012A CN 102549430 A CN102549430 A CN 102549430A
- Authority
- CN
- China
- Prior art keywords
- cells
- cell
- biosensor
- marker
- molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23039809P | 2009-07-31 | 2009-07-31 | |
| US61/230,398 | 2009-07-31 | ||
| US23080109P | 2009-08-03 | 2009-08-03 | |
| US61/230,801 | 2009-08-03 | ||
| PCT/US2010/043336 WO2011014485A2 (en) | 2009-07-31 | 2010-07-27 | Methods to characterize cell reprogramming and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102549430A true CN102549430A (zh) | 2012-07-04 |
Family
ID=42556980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800430122A Pending CN102549430A (zh) | 2009-07-31 | 2010-07-27 | 表征细胞重编程的方法及其应用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20110028345A1 (https=) |
| EP (1) | EP2460008A2 (https=) |
| JP (1) | JP2013500718A (https=) |
| CN (1) | CN102549430A (https=) |
| IN (1) | IN2012DN00852A (https=) |
| WO (1) | WO2011014485A2 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111239130A (zh) * | 2018-11-28 | 2020-06-05 | 中国科学院大连化学物理研究所 | 一种无标记内皮素受体细胞模型构建和筛选的方法及应用 |
| CN113167793A (zh) * | 2018-11-20 | 2021-07-23 | 豪夫迈·罗氏有限公司 | 用于在传感器表面上接种细胞的方法 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11229789B2 (en) | 2013-05-30 | 2022-01-25 | Neurostim Oab, Inc. | Neuro activator with controller |
| EP3441109A1 (en) | 2013-05-30 | 2019-02-13 | Graham H. Creasey | Flexible dermal patch for a topical nerve stimulator system |
| US20170363614A1 (en) * | 2014-12-22 | 2017-12-21 | Enumeral Biomedical Holdings, Inc. | Methods For Screening Therapeutic Compounds |
| US11077301B2 (en) | 2015-02-21 | 2021-08-03 | NeurostimOAB, Inc. | Topical nerve stimulator and sensor for bladder control |
| WO2019094365A1 (en) | 2017-11-07 | 2019-05-16 | Neurostim Oab, Inc. | Non-invasive nerve activator with adaptive circuit |
| CA3144957A1 (en) | 2019-06-26 | 2020-12-30 | Neurostim Technologies Llc | Non-invasive nerve activator with adaptive circuit |
| CN112345745A (zh) * | 2019-08-07 | 2021-02-09 | 中国科学院大连化学物理研究所 | 无标记血管紧张素ⅱ受体细胞模型构建和筛选方法及应用 |
| WO2021126921A1 (en) | 2019-12-16 | 2021-06-24 | Neurostim Solutions, Llc | Non-invasive nerve activator with boosted charge delivery |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040147045A1 (en) * | 2002-10-29 | 2004-07-29 | Gentel Biosurfaces, Inc. | Signal molecule arrays |
| WO2008130488A1 (en) * | 2007-04-19 | 2008-10-30 | Corning Incorporated | Live-cell signals of pathogen intrusion and methods thereof |
| US20090181409A1 (en) * | 2008-01-10 | 2009-07-16 | Ye Fang | Optical biosensor method for cell-cell interaction |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8076090B2 (en) * | 2005-04-05 | 2011-12-13 | Corning Incorporated | Label free biosensors and cells |
-
2010
- 2010-07-16 US US12/837,729 patent/US20110028345A1/en not_active Abandoned
- 2010-07-27 JP JP2012522953A patent/JP2013500718A/ja active Pending
- 2010-07-27 WO PCT/US2010/043336 patent/WO2011014485A2/en not_active Ceased
- 2010-07-27 EP EP10738126A patent/EP2460008A2/en not_active Withdrawn
- 2010-07-27 CN CN2010800430122A patent/CN102549430A/zh active Pending
- 2010-07-27 IN IN852DEN2012 patent/IN2012DN00852A/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040147045A1 (en) * | 2002-10-29 | 2004-07-29 | Gentel Biosurfaces, Inc. | Signal molecule arrays |
| WO2008130488A1 (en) * | 2007-04-19 | 2008-10-30 | Corning Incorporated | Live-cell signals of pathogen intrusion and methods thereof |
| US20090181409A1 (en) * | 2008-01-10 | 2009-07-16 | Ye Fang | Optical biosensor method for cell-cell interaction |
Non-Patent Citations (4)
| Title |
|---|
| BUZANSKA等: "Neural stem cells from human cord blood on bioengineered surfaces—Novel approach to multiparameter bio-tests", 《TOXICOLOGY》 * |
| CHO等: "Chip-based time-continuous monitoring of toxic effects on stem cell differentiation", 《ANNALS OF ANATOMY》 * |
| FANG: "Label-free cell-based assays with optical biosensors in drug discovery", 《ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES》 * |
| NAGANO等: "Large-scale identification of proteins expressed in mouse embryonic stem cells", 《PROTEOMICS》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113167793A (zh) * | 2018-11-20 | 2021-07-23 | 豪夫迈·罗氏有限公司 | 用于在传感器表面上接种细胞的方法 |
| CN111239130A (zh) * | 2018-11-28 | 2020-06-05 | 中国科学院大连化学物理研究所 | 一种无标记内皮素受体细胞模型构建和筛选的方法及应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011014485A2 (en) | 2011-02-03 |
| US20110028345A1 (en) | 2011-02-03 |
| JP2013500718A (ja) | 2013-01-10 |
| IN2012DN00852A (https=) | 2015-07-10 |
| EP2460008A2 (en) | 2012-06-06 |
| WO2011014485A3 (en) | 2011-03-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102549430A (zh) | 表征细胞重编程的方法及其应用 | |
| Eglen et al. | Primary cells and stem cells in drug discovery: emerging tools for high-throughput screening | |
| CN110709092B (zh) | 用于产生人少突胶质细胞和研究体外髓鞘形成的个性化3d神经培养系统 | |
| Baumann et al. | Comparative human and rat “neurosphere assay” for developmental neurotoxicity testing | |
| CN102292636B (zh) | 鉴定分子的方法 | |
| Pistollato et al. | Protocol for the differentiation of human induced pluripotent stem cells into mixed cultures of neurons and glia for neurotoxicity testing | |
| CN102460171A (zh) | 细胞群和混合细胞群变化的检测 | |
| CN114630900A (zh) | 用于研究皮质-纹状体-中脑神经通路的人细胞模型 | |
| US8658353B2 (en) | Liver cell toxicity assay | |
| ES2701704T3 (es) | Sistemas de ensayo tisulares funcionales no invasivos in vitro | |
| JP2025184905A (ja) | 中脳ドーパミンニューロンの生成方法、中脳ニューロンおよびその使用 | |
| Kashyap et al. | Differentiating neurons derived from human umbilical cord blood stem cells work as a test system for developmental neurotoxicity | |
| Morte et al. | Evaluation of proliferation of neural stem cells in vitro and in vivo | |
| Fröhlich | Issues with cancer spheroid models in therapeutic drug screening | |
| Dionne et al. | Efficient generation of human induced pluripotent stem cells from urine samples of patients with Fragile X syndrome | |
| Zang et al. | An engineered mouse embryonic stem cell model with survivin as a molecular marker and EGFP as the reporter for high throughput screening of embryotoxic chemicals in vitro | |
| ES2988722T3 (es) | Un método para el perfilado de la expresión de proteínas de una sola célula de células progenitoras dopaminérgicas mesencefálicas de la placa del suelo | |
| Malik et al. | Establishment of a four‐cell in vitro blood‐brain barrier model with human primary brain cells | |
| Sharlow et al. | High content screening miniaturization and single cell imaging of mature human feeder layer-free iPSC-derived neurons | |
| WO2024071280A1 (ja) | 腎毒性評価方法 | |
| JP7752604B2 (ja) | 機能的神経調節性アセンブロイド | |
| CN102985820A (zh) | 使用细胞系筛选线粒体katp调节剂的方法 | |
| Harrill | Human-derived neurons and neural progenitor cells in high content imaging applications | |
| Bernard‐Trifilo et al. | Analyzing FAK and Pyk2 in early integrin signaling events | |
| US20260125652A1 (en) | Method for evaluating nephrotoxicity |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120704 |