CN102526675B

CN102526675B - Soup for treating primary dysmenorrhea

Info

Publication number: CN102526675B
Application number: CN 201210025528
Authority: CN
Inventors: 王海荣; 张爱霞; 王爱玉; 邵俊惠; 孙淑娥
Original assignee: 王海荣
Current assignee: Nantong San Intellectual Property Service Co ltd
Priority date: 2012-01-16
Filing date: 2012-01-16
Publication date: 2013-08-21
Anticipated expiration: 2032-01-16
Also published as: CN102526675A

Abstract

The invention relates to the field of medicine formulas, in particular to soup for treating primary dysmenorrheal. The soup is technically characterized by adopting the following raw medicines in percentage by weight: 10-13 percent of Chinese angelica, 8-10 percent of rhizoma corydalis, 8-10 percent of rhizoma cyperi, 6-9 percent of Chinese yam, 6-9 percent of radix paeoniae alba, 5-8 percent of fructus corni, 4-7 percent of liquorice, 5-7 percent of leonurus, 4-7 percent of caulis spatholobi, 3-5 percent of trogopterus dung, 3-5 percent of pericarpium zanthoxyli, 4-6 percent of ginger, 3-5 percent of ligusticum chuanxiong hort, 4-6 percent of carthamus tinctorius, 2-4 percent of peach kernel, 3-5 percent of cinnamon, and 3-5 percent of fructus aurantii, using water to soak, decocting, deslagging and obtaining filtrate. The soup has the advantages of exact curative effect, low cost and no toxic and side effect.

Description

The decoction that is used for the treatment of primary dysmenorrhea

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of decoction that is used for the treatment of primary dysmenorrhea.

Background technology

As everyone knows, dysmenorrhea is common gynecological disease and frequently-occurring disease, and the cause of disease is many, the pathogenesis complexity, repeatability is big, treat thorny, especially unmarried young woman and menarche the maiden more general.Show as female menstrual period or pass through front and back, hypogastric region distending pain, cold type of pain, causalgia, twinge, dull pain, bob pain, angor, spasmic pain, tearing property pain periodically take place, pain spreads to the sacrum lower back, even relate to thigh and foot, often with General Symptoms: symptoms such as the frightened insomnia of distending pain of the breast, rectal tenesmus, agitation uncomfortable in chest, sad irritability, the heart, headache and dizzy, nausea and vomiting, stomachache diarrhoea, fatigue and weakness, pale complexion, extremity are ice-cold, dripping cold sweat, collapse faintnesses.High, the scope of its morbidity wide, the cycle is near, painful big, has had a strong impact on numerous women's working and learning, has reduced the quality of life.Dysmenorrhea generally is divided into primary dysmenorrhea and secondary dysmenorrhea two classes.Fail to find that through detailed gynecological clinic inspection pelvic organ has obviously unusual person, claim primary dysmenorrhea, also claim primary dysmenorrhea.

The generation of the sick warp of constitutional is except body constitution, Nervous and Mental Factors, and is mainly too high relevant with interior prostaglandin (PG) the F2 alpha content of patient's secretory endometrium.So dysmenorrhea often occurs in the menstrual cycle of ovulation.PGF2 α is synthetic in the secretory endometrium under the progestogen action, and its receptor is in uterine muscular, the menstrual endometrium fragmentation, PGF2 α namely is released, and stimulates uterus muscle to shrink strongly, and intra-uterine pressure is increased, regional blood flow reduces, ischemia, anoxia, thus cause pain.In addition, cervical canal is narrow, and the uterus is excessively inclined in the wrong, causes the menses outflow not smooth, also can cause dysmenorrhea.

At present Western medicine does not still have the specific treatment ways and means, symptomatic treatment medicine commonly used: as analgesic: ibuprofen, aspirin, bucinnazine etc., but the part patient has gastrointestinal reaction even causes ulcer.Even there is the part young woman to be the strong analgesic of state control such as alleviating pain injection morphine, dolantin.

Summary of the invention

Purpose of the present invention is exactly in order to overcome above-mentioned existing technical deficiency, and a kind of determined curative effect is provided, and is with low cost, the decoction that is used for the treatment of primary dysmenorrhea that has no side effect.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of decoction that is used for the treatment of primary dysmenorrhea, adopt Radix Angelicae Sinensis, Rhizoma Corydalis, Rhizoma Cyperi, Rhizoma Dioscoreae, the Radix Paeoniae Alba, Fructus Corni, Radix Glycyrrhizae, Herba Leonuri, Caulis Spatholobi, Oletum Trogopterori, Fructus Zanthoxyli, Rhizoma Zingiberis Recens, Rhizoma Chuanxiong, Flos Carthami, Semen Persicae, Cortex Cinnamomi, Fructus Aurantii is crude drug, be soaked in water, remove slag after decocting filtrate, raw material is formed: Radix Angelicae Sinensis 10～13%, Rhizoma Corydalis 8～10%, Rhizoma Cyperi 8～10%, Rhizoma Dioscoreae 6～9%, the Radix Paeoniae Alba 6～9%, Fructus Corni 5～8%, Radix Glycyrrhizae 4～7%, Herba Leonuri 5～7%, Caulis Spatholobi 4～7%, Oletum Trogopterori 3～5%, Fructus Zanthoxyli 3～5%, Rhizoma Zingiberis Recens 4～6%, Rhizoma Chuanxiong 3～5%, Flos Carthami 4～6%, Semen Persicae 2～4%, Cortex Cinnamomi 3～5%, Fructus Aurantii 3～5%.

The invention has the beneficial effects as follows, determined curative effect, with low cost, have no side effect.

The specific embodiment

The invention will be further described below in conjunction with embodiment:

Embodiment 1:

Adopt Radix Angelicae Sinensis, Rhizoma Corydalis, Rhizoma Cyperi, Rhizoma Dioscoreae, the Radix Paeoniae Alba, Fructus Corni, Radix Glycyrrhizae, Herba Leonuri, Caulis Spatholobi, Oletum Trogopterori, Fructus Zanthoxyli, Rhizoma Zingiberis Recens, Rhizoma Chuanxiong, Flos Carthami, Semen Persicae, Cortex Cinnamomi, Fructus Aurantii is that feedstock production forms, and its component (weight %) is Radix Angelicae Sinensis 11.6, Rhizoma Corydalis 9.2, Rhizoma Cyperi 9.2, Rhizoma Dioscoreae 6.9, the Radix Paeoniae Alba 6.9, Fructus Corni 5.6, Radix Glycyrrhizae 5.6, Herba Leonuri 5.6, Caulis Spatholobi 5.6, Oletum Trogopterori 4.6, Fructus Zanthoxyli 4.6, Rhizoma Zingiberis Recens 4.6, Rhizoma Chuanxiong 4.2, Flos Carthami 4.2, Semen Persicae 2.8, Cortex Cinnamomi 4.6, Fructus Aurantii 4.2 is got 68 kilograms of above-mentioned 17 kinds of raw material gross weights, after cleaning, at room temperature steeped 3-4 hour with the 20000ml water logging, decoct 60 minutes then, through the routine filtration of removing slag, after the autoclaving technology, gained filtrate 9000ml, the sterile bag packing, sealing, every bag of 150ml.Early, late twice (medicine) being taken before meal, each oral one bag, 10 days is a course for the treatment of, begins to take in 3-5 days in the clean back of menstruation, takes decoction of the present invention continuously 3 months.

Therapeutic Principle of the present invention: the reason that causes primary dysmenorrhea mostly is psychentonia, hyperesthesia, can improve through doctor's advice; The more weak dysmenorrhea that also easily produces of body constitution, energy relief of symptoms after the raising body constitution; Because uterus position is bad, blindly tinyly cause the menses storage to stay also to be the common cause of dysmenorrhea, can to make transference cure after the pregnancy.But also have the part dysmenorrhea to be caused by genital lesion, the deformity of reproductive tract especially is so more serious and obstinate dysmenorrhea is wanted timely diagnosis and treatment.The traditional Chinese medical science thinks that dysmenorrhea is that menses are not smooth, caused by energy stagnation and blood stasis, and " stagnation of QI and blood may bring about pain " is the most basic viewpoint of the traditional Chinese medical science.Primary disease since feelings will do not relax, depression of liver-QI, obstruction of QI move not freely, the formation stagnation of QI is had a pain; Or menstrual period, puerperal because of positive QI-insufficiency, be subjected to the cold-evil again, or menstrual period by cold water or sewage is invaded and the lower part of the body, or the cold and cool raw food of surfeit, cold-evil's passages through which vital energy circulates that stagnates forms cold stagnating and have a pain, or because of physical weakness, insufficiency of vital energy and blood, vessels of the uterus lose is supported, not smooth not smooth through going, and causes continuously to have a pain.Can be divided into qi stagnation and blood stasis type, the sluggish type of cold-evil, QIXUELIANGXU type.Primary disease is normal various staggered cross-reference clinically.So it is principle that treatment is enriched blood with blood circulation promoting and blood stasis dispelling, depressed liver-energy dispersing and QI regulating, warming the meridian.In the component of the present invention: Radix Angelicae Sinensis promoting blood flow to regulate menstruation laxation, Rhizoma Corydalis promoting blood circulation to remove blood stasis, regulating QI to relieve pain, Rhizoma Cyperi promoting QI circulation for relieving depression, pain relieving regulating menstruation, the three is monarch drug.Modern pharmacological research shows that Radix Angelicae Sinensis has excited to the uterus and two kinds of effects of inhibition.Rhizoma Corydalis contains 15 kinds of alkaloids, and wherein Rhizoma Corydalis first element, second element, ugly element all have analgesia, sedation.Caulis Spatholobi, Rhizoma Chuanxiong, Rhizoma Dioscoreae, Herba Leonuri, Fructus Zanthoxyli, Fructus Corni are ministerial drug, share the strong muscle of then enriching blood, dredge the meridian passage, dissipating blood stasis for subsidence of swelling, warming spleen and stomach for dispelling cold.Modern pharmacological research Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain have the effect of excited uterus, bronchial smooth muscle, can make the kidney vasoconstriction, and renal blood flow reduces.Rhizoma Chuanxiong, Herba Leonuri blood circulation promoting and blood stasis dispelling, dispel the wind, the effect of promoting the circulation of QI to relieve pain, regulating menstruation dissipating blood stasis for subsidence of swelling.Caulis Spatholobi enrich blood strong muscle, dredge the meridian passage.Semen Persicae disperse blood stasis and dredge collateral, loosening bowel to relieve constipation, Fructus Zanthoxyli warming spleen and stomach for dispelling cold, pain relieving, Fructus Corni invigorating the liver and kidney, arresting seminal emission hidroschesis, the Radix Paeoniae Alba nourish blood yin fluid astringing, easing the affected liver to relieve pain, the Rhizoma Zingiberis Recens cold expelling that induces sweat, the Oletum Trogopterori eliminating stasis to stop pain, Cortex Cinnamomi warming and recuperating the gate of life kidney fire, dispersing cold for relieving pain, Fructus Aurantii has conducting blood to flow downwards, analgesic effect, is adjuvant drug altogether, and all medicines share then removing blood stasis and activating blood flow, depressed liver-energy dispersing and QI regulating, warming the meridian and enrich blood and make dysmenorrhea be dredged and separate.The present invention has that blood circulation promoting and blood stasis dispelling, warming the meridian are enriched blood, the effect of depressed liver-energy dispersing and QI regulating, pain relieving regulating menstruation, can alleviate the degree of hysterospasm effectively, is conducive to the rehabilitation of dysmenorrhea.Clinical practice treatment dysmenorrhea obtains good curative effect.

But each raw material of the present invention also embodiment of the listed ratio of according to the form below (percentage by weight) mixing is realized.Its processing technique is identical with embodiment 1.

Below in conjunction with my institute, i.e. the clinical trial carried out of Shandong Province Wendeng Central Hospital, Weihai City is done further, is described in detail the present invention:

1, case is selected: this organizes 182 examples, age 17-48 year, course of disease 1-27.

2, Therapeutic Method: early, late twice (medicine) being taken before meal, each oral one bag, one bag of 150ml, 10 days is a course for the treatment of, begins to take in 3-5 days in the clean back of menstruation, takes decoction of the present invention continuously 3 months.

3, diagnostic criteria 1. lower abdominal pain persistence or paroxysmal pain, is aggravated gradually or rapidly at a few hours before can or rising when menstrual onset, pain degree differs, and it is spastic that weight person is, and the position is on pubis, can be radiated to lumbosacral region and burst inboard, last 2～3, spontaneous remission.2. pain is often with lumbosacral region acid, and complexion is turned white, and is in a cold sweat, and fear of cold is felt sick, vomiting or diarrhoea, extreme cold of the limbs, frequent micturition and malaise sometimes.

4, criterion of therapeutical effect: clinical recovery: after the treatment, not recurrence of year is followed up a case by regular visits in the symptom complete obiteration; Produce effects: symptom disappears substantially, and menstrual period, abdominal part felt uncomfortable slightly; Effectively: sx, follow up a case by regular visits in 1 year and still have recurrence; Invalid: after the treatment, symptom is not seen improvement.

5, therapeutic outcome: control 182 examples altogether, clinical recovery 148 examples, produce effects 24 examples, effective 7 examples, invalid 3 examples, total effective rate is 98.4%.

Claims

1. decoction that is used for the treatment of primary dysmenorrhea, it is characterized in that: adopt Radix Angelicae Sinensis, Rhizoma Corydalis, Rhizoma Cyperi, Rhizoma Dioscoreae, the Radix Paeoniae Alba, Fructus Corni, Radix Glycyrrhizae, Herba Leonuri, Caulis Spatholobi, Oletum Trogopterori, Fructus Zanthoxyli, Rhizoma Zingiberis Recens, Rhizoma Chuanxiong, Flos Carthami, Semen Persicae, Cortex Cinnamomi, Fructus Aurantii is crude drug, be soaked in water, remove slag after decocting filtrate, raw material is formed and to be Radix Angelicae Sinensis 10～13% by weight percentage, Rhizoma Corydalis 8～10%, Rhizoma Cyperi 8～10%, Rhizoma Dioscoreae 6～9%, the Radix Paeoniae Alba 6～9%, Fructus Corni 5～8%, Radix Glycyrrhizae 4～7%, Herba Leonuri 5～7%, Caulis Spatholobi 4～7%, Oletum Trogopterori 3～5%, Fructus Zanthoxyli 3～5%, Rhizoma Zingiberis Recens 4～6%, Rhizoma Chuanxiong 3～5%, Flos Carthami 4～6%, Semen Persicae 2～4%, Cortex Cinnamomi 3～5%, Fructus Aurantii 3～5%.