CN103285368B - Chinese medicine composition for treating dysmenorrhea - Google Patents

Chinese medicine composition for treating dysmenorrhea Download PDF

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CN103285368B
CN103285368B CN201310276643.4A CN201310276643A CN103285368B CN 103285368 B CN103285368 B CN 103285368B CN 201310276643 A CN201310276643 A CN 201310276643A CN 103285368 B CN103285368 B CN 103285368B
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rhizoma
chinese medicine
medicine composition
pain
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CN103285368A (en
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魏茂芳
李德敏
刘敏
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Abstract

The invention discloses a Chinese medicine composition for treating dysmenorrhea. The Chinese medicine composition is prepared from ligusticum wallichii, pollen typhae, trogopterus dung, rhizoma corydalis, fructus evodiae, rhizoma zingiberis, cinnamon, rhizoma curculiginis, cassia twig, rose, parched white peony root, safflower carthamus, rhizoma cyperi, dogwood, radix linderae, leonurus, and honey-fried licorice root in a certain proportion by weight. The Chinese medicine composition has the efficacies of regulating menstruation, relieving pain, nourishing blood, regulating the liver, warming channel, expelling cold, promoting the circulation of Qi, and dispersing blood stasis, and can be used for effectively treating the dysmenorrhea.

Description

A kind of Chinese medicine composition for the treatment of dysmenorrhea
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of dysmenorrhea.
Background technology
Dysmenorrhea refer to gynecologic menstrual or through row before and after occur lower abdomen pain or pain draw waist sacrum, even severe pain is fainted, again claim " abdominal pain during menstruation ".Dysmenorrhea is divided into primary dysmenorrhea and secondary dysmenorrhea, and the former claims again primary dysmenorrhea, refers to that genitals is without organic disease.According to statistics, more than 50% can there is dysmenorrhea in postpubertal women, and 10%~20% symptom is quite serious, affected normal life, working and learning.The traditional Chinese medical science is called " abdominal pain during menstruation ", think that before and after gynecologic menstrual or menstrual period, the sea of blood is let out excessive by being completely full of, QI and blood changes hurried, at this moment paathogenic factor is hindered as feelings will, daily life accidentally or six climate exopathogens cause harm and wait and can seize the opportunity to worm one's way into, cause punching times stasis blocking or a cold accumulating in meridian, make QI-blood circulation not smooth, the circulation of uterus menses is obstructed, so that stagnation of QI and blood may bring about pain, or punching to appoint a uterus to lose in moistening foster, not Rong Ze pain.Main clinical manifestation is: before and after row or in menstrual period lower abdomen and waist and sacrum pain, very acute pain unbearably, and with pale complexion, be in a cold sweat, deadly cold hand and foot, nausea and vomiting etc.Doctor trained in Western medicine adopts the therapies such as analgesia, calmness, spasmolytic and hormone preparation more, though can respite pain, late result is unsatisfactory, and has dyspepsia, nauseating, heartburn, diarrhoea, constipation, headache, dizziness, the side effect such as drowsiness.Chinese medicine dysmenorrhea has unique advantage and rich experience, and clinical efficacy is remarkable and side effect is less.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition, this Chinese medicine composition has determined curative effect, safe without toxic side effect, taking convenience, cheap feature for treatment dysmenorrhea.
The present invention selects Rhizoma Chuanxiong, Pollen Tyjphae, Oletum Trogopterori, Rhizoma Corydalis, Fructus Evodiae, Rhizoma Zingiberis, Cortex Cinnamomi, Rhizoma Curculiginis, Ramulus Cinnamomi, Flos Rosae Rugosae, Radix Paeoniae Alba (parched), Flos Carthami, Rhizoma Cyperi, Fructus Corni, the Radix Linderae, Herba Leonuri, Radix Glycyrrhizae Preparata to combine, make each efficacy of drugs produce synergism these drug regimens, make it to there is menstruction regulating and pain relieving, nourish blood and adjust effect of liver, dispelling cold by warming the meridian, regulating qi to disperse stagnation, thereby can effectively treat dysmenorrhea.
The effect of Chinese medicine of the present invention:
Wherein:
Rhizoma Chuanxiong: be the rhizome of samphire Rhizoma Chuanxiong.Nature and flavor are pungent, temperature.Return liver, gallbladder, pericardium channel.Effect: blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping.
Pollen Tyjphae: be the dry pollen of Typhaceae plant Typha angustifolia Herba Typhae Typha angustifolia L., typha orientalis T.orientalis Presl or congener.Nature and flavor are sweet, micro-pungent, flat.Return liver, the heart, spleen channel.Effect: hemostasis; Blood stasis dispelling; Diuresis.
Oletum Trogopterori: for the animal trogopterus xanthipes Milne-Edwards Trogopterus xanthipes Milne-Edwards of flying squirrel section or fly the dry feces of the little flying squirrel Pteromys of murine volans L..Nature and flavor are sweet, temperature.Enter liver, spleen channel.Effect: promoting the circulation of blood pain relieving.Oletum Trogopterori compatibility Rhizoma Cyperi: Oletum Trogopterori activating blood and removing stasis pain relieving; The pain relieving of Rhizoma Cyperi depressed liver-energy dispersing and QI regulating, Papillary has effect of depressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain.Oletum Trogopterori compatibility Pollen Typhae: the two is activating blood and removing stasis all. but Oletum Trogopterori is bitter sweet warm in nature raw with promoting blood circulation to remove blood stasis, promoting the circulation of QI to relieve pain hemostasis of becoming silted up of dispelling for stir-fry; Pollen Typhae sweet pungent cool in nature raw with cooling blood for hemostasis, silts that disappear of invigorating blood circulation, hold concurrently can stop blooding stir-fry astringent therapy merit specially stop blooding, two medicines life product phases 5 be with there being promoting blood circulation, the merit of the silt pain relieving of dispelling.Oletum Trogopterori compatibility Rhizoma Zingiberis: Oletum Trogopterori activating blood circulation to dissipate blood stasis pain relieving; Rhizoma Zingiberis warming spleen and stomach for dispelling cold. the two 5 use is played the merit of warming spleen and stomach for dispelling cold, promoting blood circulation and stopping pain altogether.
Rhizoma Corydalis: be Papaveraceae Corydalis perennial herb.Nature and flavor temperature, bitter, pungent.Return liver, the heart, stomach warp.Effect: promoting the circulation of QI to relieve pain.
Fructus Evodiae: be rutaceae Fructus Evodiae Evodia rutaecarpa(Juss.) Benth., Shi Hu Evodia rutaecarpa(Juss.) Benth. var. officinalis (Dode) Huang or dredge a dry almost ripe fruit of hair Fructus Evodiae Evodia rutaecarpa (Juss.) Benth. var. bodinieri (Dode) Huang.Nature and flavor are pungent, bitter, heat; Slightly poisonous.Return liver, spleen, stomach, kidney channel.Effect: dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.
Rhizoma Zingiberis: be the dry rhizome of zingiber Zingiber officinale Rosc..Nature and flavor are pungent, heat.Return spleen, stomach, the heart, lung meridian.Effect: warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation.
Cortex Cinnamomi: be the bark of canella Cortex Cinnamomi.The large heat of nature and flavor, pungent, sweet.Return kidney, spleen, the heart, Liver Channel.Effect: dispersing cold for relieving pain, warming the spleen and stomach, removing accumulated cold.
Rhizoma Curculiginis: be the dry rhizome of amrallid Rhizoma Curculiginis Curculigo orchioides Gaertn..Nature and flavor are pungent, and temperature is poisonous.Enter kidney, Liver Channel.Effect: the kidney warming sun, strengthening bone and muscle.
Ramulus Cinnamomi: be the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.Nature and flavor acrid, sweet, warm.Enter bladder, the heart, lung meridian.Effect: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
Flos Rosae Rugosae: be the dry flower of rosaceous plant Flos Rosae Rugosae Rosa rugosa Thunb..Sweet, the micro-hardship of nature and flavor, temperature.Return liver, spleen channel.Effect: promoting QI circulation for relieving depression, and blood, pain relieving, strong liver and nourishing stomach, promoting blood flow to regulate menstruation, loosening bowel to relieve constipation, resolving stagnation for tranquilization.
Radix Paeoniae Alba (parched): be the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae (cultigen).Radix Paeoniae Alba sheet is fried to micro-Huang with slow fire with bran, slightly focal spot, and sieve removes Testa Tritici, dries in the air cool.Nature and flavor hardship, acid, cool.Return liver, spleen channel.Effect: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.
Flos Carthami: be the tubular corolla of feverfew Flos Carthami Carthamus tinctorius L..Nature and flavor are pungent, warm.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.
Rhizoma Cyperi: be the dry rhizome of sedge dried tuber Cyperus rotundus L..Pungent, the micro-bitter, sweet, flat of nature and flavor.Enter liver, tri-jiao channel.Effect: the resolving depression of regulating the flow of vital energy; Menstruction regulating and pain relieving; Antiabortive.
Fructus Corni: be the drying and ripening sarcocarp of Cornaceae plant Fructus Corni Cornus officinalis Sieb. et Zucc..Nature and flavor acid, puckery, tepor.Return liver, kidney channel.Effect: liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating, controlling nocturnal emission with astringent drugs reducing urination, leukorrhagia stopping only collapses, hidroschesis.
The Radix Linderae: be the dried root of canella Radix Linderae Lindera aggregata (Sims) Kosterm..Nature and flavor are pungent, temperature.Return lung, spleen, kidney, urinary bladder channel.Effect: promoting the circulation of QI to relieve pain, warming kidney for dispelling cold.
Herba Leonuri: be the fresh or dry aerial parts of labiate Herba Leonuri Leonurus japonicus Houtt..Nature and flavor are pungent, bitter, are slightly cold.Enter the heart, liver, urinary bladder channel.Effect: invigorate blood circulation, blood stasis dispelling, regulating menstruation, water disappears.
Radix Glycyrrhizae Preparata: for the honey of Radix Glycyrrhizae is smoked processed goods.Nature and flavor are flat, sweet.GUIXIN, lung, spleen, stomach warp.Effect: spleen reinforcing stomach function regulating, QI invigorating.
Medicine material consumption of the present invention is groped in a large number to sum up through inventor and is drawn, each raw material consumption is for all to have good curative effect in following weight parts scope: Rhizoma Chuanxiong 7-17 part, Pollen Tyjphae 10-20 part, Oletum Trogopterori 4-14 part, Rhizoma Corydalis 15-25 part, Fructus Evodiae 3-9 part, Rhizoma Zingiberis 25-35 part, Cortex Cinnamomi 7-17 part, Rhizoma Curculiginis 15-25 part, Ramulus Cinnamomi 15-25 part, Flos Rosae Rugosae 7-17 part, Radix Paeoniae Alba (parched) 13-23 part, Flos Carthami 7-17 part, Rhizoma Cyperi 10-20 part, Fructus Corni 7-17 part, Radix Linderae 4-14 part, Herba Leonuri 10-20 part, Radix Glycyrrhizae Preparata 7-17 part.
Wherein be preferably: 12 parts of Rhizoma Chuanxiongs, 15 parts of Pollen Tyjphae, 9 parts of Oletum Trogopteroris, 20 parts of Rhizoma Corydalis, 6 parts of Fructus Evodiaes, 30 parts of Rhizoma Zingiberiss, 12 parts of Cortex Cinnamomis, 20 parts of Rhizoma Curculiginises, 20 parts of Ramulus Cinnamomi, 12 parts of Flos Rosae Rugosaes, 18 parts of Radix Paeoniae Alba (parched)s, 12 parts, Flos Carthami, 15 parts of Rhizoma Cyperis, 12 parts of Fructus Corni, 9 parts of the Radixs Linderae, 15 parts of Herba Leonuris, 12 parts of Radix Glycyrrhizae Preparatas.
Medicine of the present invention can adopt the conventional preparation technology of Chinese medicine preparation, can be made into said dosage form on any pharmaceutics, as pill, powder, tablet, capsule, granule, syrup, oral liquid etc.For example these crude drug grind into fine powder mix homogeneously can be made to powder takes after mixing it with water; Can use decocting, obtain after filtration filtrate, add antiseptic to make oral liquid; Also can directly take if desired decoction.
Medicine of the present invention has menstruction regulating and pain relieving, effects such as adjusting liver, dispelling cold by warming the meridian, regulating qi to disperse stagnation nourishes blood, and determined curative effect, safe without toxic side effect, taking convenience, cheap, according to clinical 200 routine patients are observed to statistics, use 90%, two of one of the medicine of the present invention total effective rate course for the treatment of total effective rate course for the treatment of 99%.
Detailed description of the invention
Embodiment mono-, 7 parts of Rhizoma Chuanxiongs, 10 parts of Pollen Tyjphae, 4 parts of Oletum Trogopteroris, 15 parts of Rhizoma Corydalis, 3 parts of Fructus Evodiaes, 25 parts of Rhizoma Zingiberiss, 7 parts of Cortex Cinnamomis, 15 parts of Rhizoma Curculiginises, 15 parts of Ramulus Cinnamomi, 7 parts of Flos Rosae Rugosaes, 13 parts of Radix Paeoniae Alba (parched)s, 7 parts, Flos Carthami, 10 parts of Rhizoma Cyperis, 7 parts of Fructus Corni, 4 parts of the Radixs Linderae, 10 parts of Herba Leonuris, 7 parts of Radix Glycyrrhizae Preparatas.
Embodiment bis-, 12 parts of Rhizoma Chuanxiongs, 15 parts of Pollen Tyjphae, 9 parts of Oletum Trogopteroris, 20 parts of Rhizoma Corydalis, 6 parts of Fructus Evodiaes, 30 parts of Rhizoma Zingiberiss, 12 parts of Cortex Cinnamomis, 20 parts of Rhizoma Curculiginises, 20 parts of Ramulus Cinnamomi, 12 parts of Flos Rosae Rugosaes, 18 parts of Radix Paeoniae Alba (parched)s, 12 parts, Flos Carthami, 15 parts of Rhizoma Cyperis, 12 parts of Fructus Corni, 9 parts of the Radixs Linderae, 15 parts of Herba Leonuris, 12 parts of Radix Glycyrrhizae Preparatas.
Embodiment tri-, 17 parts of Rhizoma Chuanxiongs, 20 parts of Pollen Tyjphae, 14 parts of Oletum Trogopteroris, 25 parts of Rhizoma Corydalis, 9 parts of Fructus Evodiaes, 35 parts of Rhizoma Zingiberiss, 17 parts of Cortex Cinnamomis, 25 parts of Rhizoma Curculiginises, 25 parts of Ramulus Cinnamomi, 17 parts of Flos Rosae Rugosaes, 23 parts of Radix Paeoniae Alba (parched)s, 17 parts, Flos Carthami, 20 parts of Rhizoma Cyperis, 17 parts of Fructus Corni, 14 parts of the Radixs Linderae, 20 parts of Herba Leonuris, 17 parts of Radix Glycyrrhizae Preparatas.
The clinical statistics data that patient uses medicine of the present invention below:
One, physical data
Accept patient's totally 200 examples for medical treatment, 21 years old mean age.
Two, tcm diagnosis standard
1, menstrual period or before and after row lower abdomen pain, pain and waist sacrum, very faint.Be periodical attack.
2, be apt to occur in young maiden.
3, due to eliminating pelvic cavity organic disease, suffer from abdominal pain.
Three, Therapeutic Method
According to drug weight proportioning of the present invention (taking embodiment bis-as standard), weighting raw materials (daily dose), filter and remove residue after decocting, services once decoction being taken warmly sooner or later.Premenstrual 1 week oral, and extremely through only withdrawing, serveing on 3 menstrual cycle is a course for the treatment of.
Four, efficacy assessment standard
Cure: pain disappears, and recurrence is seen at continuous 3 menstrual cycle ends.
Take a turn for the better: pain relief or pain disappear, but can not maintain more than 3 months.
Do not heal: pain has no improvement.
Five, therapeutic outcome statistics
Wherein: total effective rate=cure rate+improvement rate
Model case and curative effect:
Case one, Zhang, 23 years old, dysmenorrhea half a year.Since patient half a year, often to menstrual period and the 1st day cold and pain in the lower abdomen of passing through, desire for warm and being pressed, obtains warm alleviation of pain, and with lumbus sacrum pain, cold, the bearing down of acid, when serious with nausea and vomiting.Hypomenorrhea, color is dark, has clot and film sample to strip off.Pass through at every turn and need take ibuprofen, affect orthobiosis and work.The symptom of this time passing through while examining aggravation, waist abdomen cold type of pain is hard to bear, and cold sweat occurs frequently, and leucorrhea is on the high side, and rare clearly, light red tongue is dark, white and moist fur, deep pulse.Patient took after the course for the treatment of of Chinese medicine of the present invention, before menstrual period and pass through that waist stomachache is basic to disappear, discharged a small amount of clot, had no film sample thing, did not use analgesic.
Case two, Wu, 36 years old, dysmenorrhea was more than 6 years.Patient's lower abdomen pain in each menstrual period, Hypomenorrhea, dark through color, there is clot, distention and pain of breast before menstruation, stringy and thready pulse, the dark tongue of light red tongue is white, and yellowish urine is defecated partially dry.Patient is irascible temperament usually, and before passing through, temper is large at every turn, easily irritated, irritability.Patient took after two courses for the treatment of of Chinese medicine of the present invention, and while passing through, stomachache disappears, and disposition takes a turn for the better.
Case three, Liu, 22 years old, dysmenorrhea 5 years.When patient is serious, can not do anything, must eat tablet for alleviating pain bed, first day pain is serious, less through measuring when pain, crossed first day after pain alleviate gradually.Patient took after two courses for the treatment of of Chinese medicine of the present invention, pain relief.

Claims (2)

1. treat the Chinese medicine composition of dysmenorrhea for one kind, it is characterized in that, this Chinese medicine composition is the ingredients by following weight portion: Rhizoma Chuanxiong 7-17 part, Pollen Tyjphae 10-20 part, Oletum Trogopterori 4-14 part, Rhizoma Corydalis 15-25 part, Fructus Evodiae 3-9 part, Rhizoma Zingiberis 25-35 part, Cortex Cinnamomi 7-17 part, Rhizoma Curculiginis 15-25 part, Ramulus Cinnamomi 15-25 part, Flos Rosae Rugosae 7-17 part, Radix Paeoniae Alba (parched) 13-23 part, Flos Carthami 7-17 part, Rhizoma Cyperi 10-20 part, Fructus Corni 7-17 part, Radix Linderae 4-14 part, Herba Leonuri 10-20 part, Radix Glycyrrhizae Preparata 7-17 part.
2. according to the Chinese medicine composition of the treatment dysmenorrhea described in claims 1, it is characterized in that the ingredients by following weight portion: 12 parts of Rhizoma Chuanxiongs, 15 parts of Pollen Tyjphae, 9 parts of Oletum Trogopteroris, 20 parts of Rhizoma Corydalis, 6 parts of Fructus Evodiaes, 30 parts of Rhizoma Zingiberiss, 12 parts of Cortex Cinnamomis, 20 parts of Rhizoma Curculiginises, 20 parts of Ramulus Cinnamomi, 12 parts of Flos Rosae Rugosaes, 18 parts of Radix Paeoniae Alba (parched)s, 12 parts, Flos Carthami, 15 parts of Rhizoma Cyperis, 12 parts of Fructus Corni, 9 parts of the Radixs Linderae, 15 parts of Herba Leonuris, 12 parts of Radix Glycyrrhizae Preparatas.
CN201310276643.4A 2013-07-03 2013-07-03 Chinese medicine composition for treating dysmenorrhea Expired - Fee Related CN103285368B (en)

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CN104544586A (en) * 2015-02-04 2015-04-29 南安市荣兴专利技术转移中心有限公司 Healthcare underwear for preventing and treating women dysmenorrhea
CN105169338A (en) * 2015-10-10 2015-12-23 临沂草之美医药科技有限公司 Medicine composition for treating female climacteric syndromes and preparation method thereof
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