CN103285368A - Chinese medicine composition for treating dysmenorrhea - Google Patents

Chinese medicine composition for treating dysmenorrhea Download PDF

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CN103285368A
CN103285368A CN2013102766434A CN201310276643A CN103285368A CN 103285368 A CN103285368 A CN 103285368A CN 2013102766434 A CN2013102766434 A CN 2013102766434A CN 201310276643 A CN201310276643 A CN 201310276643A CN 103285368 A CN103285368 A CN 103285368A
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rhizoma
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魏茂芳
李德敏
刘敏
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魏茂芳
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Abstract

The invention discloses a Chinese medicine composition for treating dysmenorrhea. The Chinese medicine composition is prepared from ligusticum wallichii, pollen typhae, trogopterus dung, rhizoma corydalis, fructus evodiae, rhizoma zingiberis, cinnamon, rhizoma curculiginis, cassia twig, rose, parched white peony root, safflower carthamus, rhizoma cyperi, dogwood, radix linderae, leonurus, and honey-fried licorice root in a certain proportion by weight. The Chinese medicine composition has the efficacies of regulating menstruation, relieving pain, nourishing blood, regulating the liver, warming channel, expelling cold, promoting the circulation of Qi, and dispersing blood stasis, and can be used for effectively treating the dysmenorrhea.

Description

A kind of Chinese medicine composition for the treatment of dysmenorrhea
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of dysmenorrhea.
Background technology
Dysmenorrhea refers to gynecologic menstrual or lower abdomen pain occurs or pain is drawn the waist sacrum before and after row, even severe pain faints, and claims again " abdominal pain during menstruation ".Dysmenorrhea is divided into primary dysmenorrhea and secondary dysmenorrhea, and the former claims primary dysmenorrhea again, refers to that the genitals does not have organic disease.According to statistics, dysmenorrhea can take place in postpubertal women more than 50%, and 10%~20% symptom is quite serious, has influenced normal life, working and learning.The traditional Chinese medical science is called " abdominal pain during menstruation ", think that the sea of blood is let out excessive before and after gynecologic menstrual or menstrual period by completely being full of, QI and blood changes hurried, at this moment paathogenic factor such as feelings will are hindered, daily life accidentally or six climate exopathogens cause harm and wait and can seize the opportunity to worm one's way into, cause dashing and appoint the stasis of blood to hinder or a cold accumulating in meridian, make QI-blood circulation not smooth, the circulation of uterus menses is obstructed, so that stagnation of QI and blood may bring about pain, or foster towards appointing a uterus to lose in moistening, and Rong Ze is bitterly.Main clinical manifestation is: before and after row or in menstrual period lower abdomen and waist and sacrum pain, very then acute painful unbearably, and with pale complexion, be in a cold sweat, deadly cold hand and foot, nausea and vomiting etc.Doctor trained in Western medicine adopts therapies such as analgesia, calmness, spasmolytic and hormone preparation more, though can respite pain, late result is unsatisfactory, and dyspepsia, nauseating, heartburn, diarrhoea, constipation, headache, dizziness, side effect such as drowsiness are arranged.The Chinese medicine dysmenorrhea has special advantages and rich experience, and clinical efficacy is remarkable and side effect is less.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition, this Chinese medicine composition has determined curative effect, safe without toxic side effect, taking convenience, cheap characteristics for the treatment dysmenorrhea.
The present invention selects Rhizoma Chuanxiong, Pollen Tyjphae, Oletum Trogopterori, Rhizoma Corydalis, Fructus Evodiae, Rhizoma Zingiberis, Cortex Cinnamomi, Rhizoma Curculiginis, Ramulus Cinnamomi, Flos Rosae Rugosae, Radix Paeoniae Alba (parched), Flos Carthami, Rhizoma Cyperi, Fructus Corni, the Radix Linderae, Herba Leonuri, Radix Glycyrrhizae Preparata to make up, make each efficacy of drugs produce synergism these drug regimens, make it to have menstruction regulating and pain relieving, nourish blood and transfer the effect of liver, dispelling cold by warming the meridian, regulating qi to disperse stagnation, thereby can effectively treat dysmenorrhea.
The effect of Chinese medicine of the present invention:
Wherein:
Rhizoma Chuanxiong: be samphire Rhizoma Chuanxiong rhizome.The nature and flavor suffering, temperature.Return liver, gallbladder, pericardium channel.Effect: blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping.
Pollen Tyjphae: be the dry pollen of Typhaceae plant raupo Herba Typhae Typha angustifolia L., typha orientalis T.orientalis Presl or congener.Sweet, the little suffering of nature and flavor, flat.Return liver, the heart, spleen channel.Effect: hemostasis; Blood stasis dispelling; Diuresis.
Oletum Trogopterori: be the dry feces of the animal trogopterus xanthipes Milne-Edwards Trogopterus xanthipes Milne-Edwards of flying squirrel section or the little flying squirrel Pteromys of flying squirrel section animal volans L..Nature and flavor are sweet, temperature.Go into liver, spleen channel.Effect: promoting the circulation of blood pain relieving.Oletum Trogopterori compatibility Rhizoma Cyperi: Oletum Trogopterori activating blood and removing stasis pain relieving; The pain relieving of Rhizoma Cyperi depressed liver-energy dispersing and QI regulating, the two has share the effect of depressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain.Oletum Trogopterori compatibility Pollen Typhae: the two is activating blood and removing stasis all. but bitter sweet warm in nature the giving birth to promoting blood circulation to remove blood stasis, promoting the circulation of QI to relieve pain of Oletum Trogopterori fried with the hemostasis of becoming silted up of then dispelling; The sweet suffering of Pollen Typhae is cool in nature gives birth to cooling blood for hemostasis, silts that disappear of invigorating blood circulation, hold concurrently can stop blooding stir-fry with astringent therapy then merit specially stop blooding, the living product phase 5 of two medicines be with promoting blood circulation is arranged, the merit of the silt pain relieving of dispelling.Oletum Trogopterori compatibility Rhizoma Zingiberis: Oletum Trogopterori activating blood circulation to dissipate blood stasis pain relieving; The Rhizoma Zingiberis warming spleen and stomach for dispelling cold. the two 5 usefulness is played the merit of warming spleen and stomach for dispelling cold, promoting blood circulation and stopping pain altogether.
Rhizoma Corydalis: be Papaveraceae Corydalis perennial herb.The nature and flavor temperature, bitter, hot.Return liver, the heart, stomach warp.Effect: promoting the circulation of QI to relieve pain.
Fructus Evodiae: be rutaceae Fructus Evodiae Evodia rutaecarpa(Juss.) Benth., Shi Hu Evodia rutaecarpa(Juss.) Benth. var. officinalis (Dode) Huang or dredge the dry almost ripe fruit of hair Fructus Evodiae Evodia rutaecarpa (Juss.) Benth. var. bodinieri (Dode) Huang.Nature and flavor suffering, hardship, heat; Slightly poisonous.Return liver, spleen, stomach, kidney channel.Effect: dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.
Rhizoma Zingiberis: be the dry rhizome of zingiber Zingiber officinale Rosc..The nature and flavor suffering, heat.Return spleen, stomach, the heart, lung meridian.Effect: warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation.
Cortex Cinnamomi: be the bark of canella Cortex Cinnamomi.The big heat of nature and flavor, hot, sweet.Return kidney, spleen, the heart, Liver Channel.Effect: dispersing cold for relieving pain, warming the spleen and stomach, removing accumulated cold.
Rhizoma Curculiginis: be the dry rhizome of amrallid Rhizoma Curculiginis Curculigo orchioides Gaertn..The nature and flavor suffering, temperature, poisonous.Go into kidney, Liver Channel.Effect: the kidney warming sun, strengthening bone and muscle.
Ramulus Cinnamomi: be the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.Nature and flavor suffering, sweet, temperature.Go into bladder, the heart, lung meridian.Effect: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
Flos Rosae Rugosae: be the dry flower of rosaceous plant Flos Rosae Rugosae Rosa rugosa Thunb..Sweet, the little hardship of nature and flavor, temperature.Return liver, spleen channel.Effect: promoting QI circulation for relieving depression, and blood, pain relieving, strong liver and nourishing stomach, promoting blood flow to regulate menstruation, loosening bowel to relieve constipation, resolving stagnation for tranquilization.
Radix Paeoniae Alba (parched): be the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae (cultigen).Radix Paeoniae Alba sheet is fried to little Huang with slow fire with bran, and slightly focal spot sieves and removes Testa Tritici, the cold of drying in the air.Nature and flavor hardship, acid, cold.Return liver, spleen channel.Effect: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.
Flos Carthami: be the tubular corolla of feverfew Flos Carthami Carthamus tinctorius L..Nature and flavor suffering, temperature.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.
Rhizoma Cyperi: be the dry rhizome of sedge dried tuber Cyperus rotundus L..Nature and flavor suffering, little hardship, sweet, flat.Go into liver, tri-jiao channel.Effect: the resolving depression of regulating the flow of vital energy; Menstruction regulating and pain relieving; Antiabortive.
Fructus Corni: be the drying and ripening sarcocarp of Cornaceae plant Fructus Corni Cornus officinalis Sieb. et Zucc..Nature and flavor acid, puckery, tepor.Return liver, kidney channel.Effect: liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating, the controlling nocturnal emission with astringent drugs reducing urination, leukorrhagia stopping only collapses, hidroschesis.
The Radix Linderae: be the dried root of canella Radix Linderae Lindera aggregata (Sims) Kosterm..The nature and flavor suffering, temperature.Return lung, spleen, kidney, urinary bladder channel.Effect: promoting the circulation of QI to relieve pain, warming kidney for dispelling cold.
Herba Leonuri: be the fresh or dry aerial parts of labiate Herba Leonuri Leonurus japonicus Houtt..Nature and flavor suffering, hardship are slightly cold.Go into the heart, liver, urinary bladder channel.Effect: invigorate blood circulation, blood stasis dispelling, regulating menstruation, water disappears.
Radix Glycyrrhizae Preparata: for the honey of Radix Glycyrrhizae is smoked processed goods.Nature and flavor are flat, and are sweet.GUIXIN, lung, spleen, stomach warp.Effect: spleen reinforcing stomach function regulating, QI invigorating.
Medicine material consumption of the present invention is groped to sum up to draw through the inventor in a large number, and each raw material consumption is for all to have curative effect preferably in the following weight parts scope: Rhizoma Chuanxiong 7-17 part, Pollen Tyjphae 10-20 part, Oletum Trogopterori 4-14 part, Rhizoma Corydalis 15-25 part, Fructus Evodiae 3-9 part, Rhizoma Zingiberis 25-35 part, Cortex Cinnamomi 7-17 part, Rhizoma Curculiginis 15-25 part, Ramulus Cinnamomi 15-25 part, Flos Rosae Rugosae 7-17 part, Radix Paeoniae Alba (parched) 13-23 part, Flos Carthami 7-17 part, Rhizoma Cyperi 10-20 part, Fructus Corni 7-17 part, Radix Linderae 4-14 part, Herba Leonuri 10-20 part, Radix Glycyrrhizae Preparata 7-17 part.
Wherein be preferably: 12 parts of Rhizoma Chuanxiongs, 15 parts of Pollen Tyjphae, 9 parts of Oletum Trogopteroris, 20 parts of Rhizoma Corydalis, 6 parts of Fructus Evodiaes, 30 parts of Rhizoma Zingiberiss, 12 parts of Cortex Cinnamomis, 20 parts of Rhizoma Curculiginises, 20 parts of Ramulus Cinnamomi, 12 parts of Flos Rosae Rugosaes, 18 parts of Radix Paeoniae Alba (parched)s, 12 parts on Flos Carthami, 15 parts of Rhizoma Cyperis, 12 parts of Fructus Corni, 9 parts of the Radixs Linderae, 15 parts of Herba Leonuris, 12 parts of Radix Glycyrrhizae Preparatas.
Medicine of the present invention can adopt the conventional preparation technology of Chinese medicine preparation, can be made into said dosage form on any pharmaceutics, as pill, powder, tablet, capsule, granule, syrup, oral liquid etc.For example these crude drug grind into fine powder mix homogeneously can be made powder takes after mixing it with water; Can use decocting, get filtrate after filtration, add antiseptic and make oral liquid; Also can directly take decoction in case of necessity.
Medicine of the present invention has menstruction regulating and pain relieving, effects such as transferring liver, dispelling cold by warming the meridian, regulating qi to disperse stagnation nourishes blood, and determined curative effect, safe without toxic side effect, taking convenience, cheap, according to clinical 200 routine patients are observed statistics, use medicine total effective rate course for the treatment of total effective rate 90%, two course for the treatment of 99% of the present invention.
The specific embodiment
Embodiment one, 7 parts of Rhizoma Chuanxiongs, 10 parts of Pollen Tyjphae, 4 parts of Oletum Trogopteroris, 15 parts of Rhizoma Corydalis, 3 parts of Fructus Evodiaes, 25 parts of Rhizoma Zingiberiss, 7 parts of Cortex Cinnamomis, 15 parts of Rhizoma Curculiginises, 15 parts of Ramulus Cinnamomi, 7 parts of Flos Rosae Rugosaes, 13 parts of Radix Paeoniae Alba (parched)s, 7 parts on Flos Carthami, 10 parts of Rhizoma Cyperis, 7 parts of Fructus Corni, 4 parts of the Radixs Linderae, 10 parts of Herba Leonuris, 7 parts of Radix Glycyrrhizae Preparatas.
Embodiment two, 12 parts of Rhizoma Chuanxiongs, 15 parts of Pollen Tyjphae, 9 parts of Oletum Trogopteroris, 20 parts of Rhizoma Corydalis, 6 parts of Fructus Evodiaes, 30 parts of Rhizoma Zingiberiss, 12 parts of Cortex Cinnamomis, 20 parts of Rhizoma Curculiginises, 20 parts of Ramulus Cinnamomi, 12 parts of Flos Rosae Rugosaes, 18 parts of Radix Paeoniae Alba (parched)s, 12 parts on Flos Carthami, 15 parts of Rhizoma Cyperis, 12 parts of Fructus Corni, 9 parts of the Radixs Linderae, 15 parts of Herba Leonuris, 12 parts of Radix Glycyrrhizae Preparatas.
Embodiment three, 17 parts of Rhizoma Chuanxiongs, 20 parts of Pollen Tyjphae, 14 parts of Oletum Trogopteroris, 25 parts of Rhizoma Corydalis, 9 parts of Fructus Evodiaes, 35 parts of Rhizoma Zingiberiss, 17 parts of Cortex Cinnamomis, 25 parts of Rhizoma Curculiginises, 25 parts of Ramulus Cinnamomi, 17 parts of Flos Rosae Rugosaes, 23 parts of Radix Paeoniae Alba (parched)s, 17 parts on Flos Carthami, 20 parts of Rhizoma Cyperis, 17 parts of Fructus Corni, 14 parts of the Radixs Linderae, 20 parts of Herba Leonuris, 17 parts of Radix Glycyrrhizae Preparatas.
Be the clinical statistics data that the patient uses medicine of the present invention below:
One, physical data
Accept patient's totally 200 examples for medical treatment, 21 years old mean age.
Two, tcm diagnosis standard
1, menstrual period or before and after row lower abdomen pain, pain and waist sacrum are very then fainted.Be periodical attack.
2, good sending out in young maiden.
3, suffer from abdominal pain due to the eliminating pelvic cavity organic disease.
Three, Therapeutic Method
According to drug weight proportioning of the present invention (be standard with embodiment two), weighting raw materials (daily dose), the decocting after-filtration removes slag, and sooner or later services once decoction being taken warmly.Rise orally through preceding 1 week, to through withdrawing only, serveing on 3 menstrual cycle is a course for the treatment of.
Four, efficacy assessment standard
Cure: pain disappears, and recurrence is seen at continuous 3 menstrual cycle ends.
Take a turn for the better: pain relief or pain disappear, but can not keep more than 3 months.
Do not heal: pain is not seen improvement.
Five, therapeutic outcome statistics
Figure 2013102766434100002DEST_PATH_IMAGE001
Wherein: total effective rate=cure rate+improvement rate
Model case and curative effect:
Case one, Zhang, 23 years old, dysmenorrhea half a year.The patient is since half a year, and whenever to menstrual period and the 1st day cold and pain in the lower abdomen of passing through, desire for warm and being pressed gets warm alleviation of pain, and with lumbus sacrum pain, cold, the bearing down of acid, when serious with nausea and vomiting.Menstrual blood volume is few, and color is dark, has clot and film sample to strip off.Pass through needs the clothes ibuprofen at every turn, influences orthobiosis and work.The symptom of this time passing through when examining aggravation, waist abdomen cold type of pain is hard to bear, and cold sweat occurs frequently, and leucorrhea is on the high side, and rare clearly, light red tongue is dark, white and moist fur, deep pulse.The patient takes Chinese medicine of the present invention after course for the treatment of, before menstrual period and pass through that waist stomachache is basic to disappear, discharges a small amount of clot, does not see film sample thing, does not use analgesic.
Case two, Wu, 36 years old, dysmenorrhea was more than 6 years.Patient's lower abdomen pain in each menstrual period, menstrual blood volume is few, and is dark through color, and clot is arranged, distention and pain of breast before menstruation, stringy and thready pulse, the dark tongue of light red tongue is white, yellowish urine, it is dried partially to defecate.The patient is irascible temperament usually, and temper is big before passing through at every turn, and is irritated easily, irritability.The patient takes Chinese medicine of the present invention after two courses for the treatment of, and stomachache disappears when passing through, and disposition takes a turn for the better.
Case three, Liu, 22 years old, dysmenorrhea 5 years.Can not do anything when the patient is serious, must eat tablet for alleviating pain bed, pain was serious in first day, and is less through measuring during pain, spent first day after pain alleviate gradually.The patient takes Chinese medicine of the present invention after two courses for the treatment of, pain relief.

Claims (2)

1. Chinese medicine composition for the treatment of dysmenorrhea, it is characterized in that this Chinese medicine composition is made up of following medicaments in part by weight: Rhizoma Chuanxiong 7-17 part, Pollen Tyjphae 10-20 part, Oletum Trogopterori 4-14 part, Rhizoma Corydalis 15-25 part, Fructus Evodiae 3-9 part, Rhizoma Zingiberis 25-35 part, Cortex Cinnamomi 7-17 part, Rhizoma Curculiginis 15-25 part, Ramulus Cinnamomi 15-25 part, Flos Rosae Rugosae 7-17 part, Radix Paeoniae Alba (parched) 13-23 part, Flos Carthami 7-17 part, Rhizoma Cyperi 10-20 part, Fructus Corni 7-17 part, Radix Linderae 4-14 part, Herba Leonuri 10-20 part, Radix Glycyrrhizae Preparata 7-17 part.
2. according to the Chinese medicine composition of claims 1 described treatment dysmenorrhea, it is characterized in that, formed by following medicaments in part by weight: 12 parts of Rhizoma Chuanxiongs, 15 parts of Pollen Tyjphae, 9 parts of Oletum Trogopteroris, 20 parts of Rhizoma Corydalis, 6 parts of Fructus Evodiaes, 30 parts of Rhizoma Zingiberiss, 12 parts of Cortex Cinnamomis, 20 parts of Rhizoma Curculiginises, 20 parts of Ramulus Cinnamomi, 12 parts of Flos Rosae Rugosaes, 18 parts of Radix Paeoniae Alba (parched)s, 12 parts on Flos Carthami, 15 parts of Rhizoma Cyperis, 12 parts of Fructus Corni, 9 parts of the Radixs Linderae, 15 parts of Herba Leonuris, 12 parts of Radix Glycyrrhizae Preparatas.
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CN104544586A (en) * 2015-02-04 2015-04-29 南安市荣兴专利技术转移中心有限公司 Healthcare underwear for preventing and treating women dysmenorrhea
CN105169338A (en) * 2015-10-10 2015-12-23 临沂草之美医药科技有限公司 Medicine composition for treating female climacteric syndromes and preparation method thereof
CN106913898A (en) * 2017-04-24 2017-07-04 赖新展 A kind of dysmenorrhoea panty liner and preparation method thereof
CN107411461A (en) * 2017-03-30 2017-12-01 戴万华 A kind of gynaecology's thermotherapy Chinese medicinal pillow
CN115120661A (en) * 2022-08-15 2022-09-30 冯玲 A topical Chinese medicinal composition for treating dysmenorrhea, and its preparation method

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Publication number Priority date Publication date Assignee Title
CN104544586A (en) * 2015-02-04 2015-04-29 南安市荣兴专利技术转移中心有限公司 Healthcare underwear for preventing and treating women dysmenorrhea
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CN107411461A (en) * 2017-03-30 2017-12-01 戴万华 A kind of gynaecology's thermotherapy Chinese medicinal pillow
CN106913898A (en) * 2017-04-24 2017-07-04 赖新展 A kind of dysmenorrhoea panty liner and preparation method thereof
CN115120661A (en) * 2022-08-15 2022-09-30 冯玲 A topical Chinese medicinal composition for treating dysmenorrhea, and its preparation method
CN115120661B (en) * 2022-08-15 2024-04-02 冯玲 A topical Chinese medicinal composition for treating dysmenorrhea, and its preparation method

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