CN102526531A - Rehmannia root, prepared rehmannia root and Chinese wolfberry root-bark yin-nourishing and pulse-regulating paste for treating menopausal syndrome - Google Patents
Rehmannia root, prepared rehmannia root and Chinese wolfberry root-bark yin-nourishing and pulse-regulating paste for treating menopausal syndrome Download PDFInfo
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Abstract
The invention relates to a rehmannia root, prepared rehmannia root and Chinese wolfberry root-bark yin-nourishing and pulse-regulating paste for treating menopausal syndrome. According to the traditional medical theories, a treatment method for invigorating kidney yin and suppressing yang is provided. The paste is prepared from rehmannia root, prepared rehmannia root, Chinese wolfberry root-bark, gromwell root, eclipta alba, glossy privet fruit, tortoise-plastron glue, turtle shell glue, medical dogwood, silktree albizia bark, thinleaf milkwort root-bark, dendrobium, dwarf lilyturf tuber, fragrant solomonseal rhizome, tangerine peel, rose, spina date seed, platycladi seed, root of red-rooted salvia, blighted wheat, fried liquoric root, black soybean, honey, Chinese rice wine, and the like. Clinical results show that the effective rate is over 97.00 percent, and the paste can comprehensively regulate the whole body of a patient, and has high pertinence and an obvious curative effect. The invention has the characteristics that: the paste is not required to be decocted when taken, is easy to carry and store and is delicious; the potency is mild, stable, lasting and can be taken in all seasons.
Description
Technical field:
The present invention relates to a kind of three locations YIN nourishing of treating perimenopausal syndrome transfers towards cream.
Background technology:
Perimenopausal syndrome (menopausal syndrome; MPS) practise title " climacteric syndrome "; Be the women before and after menopause since the estrogen level fluctuation or descend due to be main with the autonomic nervous system dysfunction, with one group of syndrome of neural mental symptoms.The traditional Chinese medicine of China does not have this name of disease, but cardinal symptoms such as its hectic fever, hyperhidrosis, agitation are had detailed argumentation, and modern TCM belongs to primary disease " menopausal syndrome " category.Along with the development of society, the quickening of rhythm of life and the enhancing of competitive spirit, the incidence rate of climacteric syndrome day by day increases; And Along with people's life-span significant prolongation, the average life process prolongs greatly behind the postmenopausal women.At present oneself has 1/5th to step into climacteric to China women, wherein has 2/3rds women's federation symptom to occur approximately.Therefore the research treatment to climacteric syndrome has great social significance and realistic meaning.To the treatment of perimenopausal syndrome, Chinese medicine is different with Hormone Replacement Therapy (HRT) starting point, and HRT pays attention to replenishing of hormone, as deals with improperly, possibly bring out breast carcinoma, carcinoma of endometrium, and possibly cause vagina irregular hemorrhage, side effect such as weight increase.From present research, Chinese medicine has good curative effect and has advantages such as side effect is little, no carcinogenic danger the treatment of perimenopausal syndrome, and therefore to the treatment of perimenopausal syndrome, Chinese medicine has the trend of alternative or additional HRT.
Summary of the invention:
The objective of the invention is to transfer towards cream for the treatment perimenopausal syndrome provides the YIN nourishing of a kind of three locations.
For realizing above purpose, technical scheme of the present invention is:
Motherland's medical science thinks, the woman is in seventy-seven year, the kidney qi degradation, and menses will exhaust; Lose towards conception vessel empty, asthenia of essence and blood, imbalance between YIN and YANG, thereby be prone to cause the generation of this disease; So traditional view is with the argument that declines of kidney void, and the branch of deficiency of the kidney yin, insufficiency of kidney-YANG is arranged, with deficiency of the kidney yin for seeing more.Proposed the nourishing kidney yin, assistant is with the Therapeutic Method of YANG hyperactivity suppressing for this reason.Its raw material is formed:
The Radix Rehmanniae 240~270g Radix Rehmanniae Preparata 240~270g Cortex Lycii 240~270g Radix Arnebiae (Radix Lithospermi) 240~270g
Herba Ecliptae 240~270g Fructus Ligustri Lucidi 240~270g Colla Plastri Testudinis 240~270g
Colla carapax Trionycis 240~270g Fructus Corni 130~160g Cortex Albiziae 130~160g
Cortex et Radix Polygalae (processed) 130~160g Herba Dendrobii 240~270g 240~270g Radix Ophiopogonis Rhizoma Polygonati Odorati 240~270g
Pericarpium Citri Reticulatae 80~120g Flos Rosae Rugosae 80~120g Semen Ziziphi Spinosae 240~270g Semen Platycladi 180~220g Radix Salviae Miltiorrhizae 240~270g Fructus Tritici Levis 480~520g Radix Glycyrrhizae Preparata 80~120g Semen sojae atricolor 480~520g Mel 480~520g yellow wine 500ml.
Method for making: above 20 four Chinese medicine things, wherein Colla Plastri Testudinis, Colla carapax Trionycis add yellow wine and dissolve, and Mel is subsequent use, and 20 flavors such as all the other Radix Rehmanniae were soaked 1 hour; Decoct secondary, each 2 hours, filter, merging filtrate left standstill 24 hours; Getting supernatant concentration to relative density is the clear paste of 1.10~1.20 (50~55 ℃), adds Mel, boils, and filters; The dissolving liquid of filtrating and Colla Plastri Testudinis, Colla carapax Trionycis and yellow wine is concentrated into the relative density of regulation, makes 1000g, promptly gets.
Instructions of taking: every day 2 times, each 20g; Boiled water is taken after mixing with liquid.
Theoretical foundation: the women is generally in the year of " seventy-seven ", and menstruation stops, and is called " menopause " or " cracked ends ", and some women is followed before and after " menopause " and some diseases relevant with menopause occurred, as warms sweating; Malaise, palpitation and insomnia, irritated irritability, vertigo and tinnitus; Or appearance, edema of lower limbs, indigestion and loss of appetite, loose stool, or menoxenia; Metrorrhagia and metrostaxis is referred to as " menopausal syndrome ", also is " menopausal syndrome ", and modern medicine is called " perimenopausal syndrome ".At present most doctor family thinks that the pathogenesis of primary disease is main to suffer from a deficiency of the kidney, and clinically sees with deficiency of the kidney yin more.
" Thorough Knowledge of Medicine Xuezheng Lun, On Blood Syndromes " pointed out: " people is able to the survivor, is the door of upright life, and the unit of meaning is refreshing, invisible fire, and the vigour of meaning, invisible water, the primordial essence of meaning is posted in the middle of two kidneys, so say among the five internal organs, only kidney is true ... ".
Kidney storing essence, kidney essense come from congenital being supported the day after tomorrow, change and give birth to kidney qi; The Kidney-Yin kidney-Yang of residing is the basic of human body negative and positive, so speech " non-this of the moon of the five internal organs can not be grown; non-this of YANG of five ZANG-organs can not be sent out " in the Jing-Yue Complete Works, it is thus clear that the kidney yin kidney yang is vigorous, then the negative and positive of whole body are vigorous; The decline of kidney yin kidney yang, then the negative and positive of whole body also fail." interior through ancient times innocent opinion " cloud: " woman ... seventy-seven, conception vessel is empty, and taichong channel declines few, exhaustion of kidney-essence with promoting reproductive function, menopause is so senile appearance and loss of fecundity are also." can find out that by containing to the change procedure that declines, the strong old variation of growth has taken place body in kidney qi, menses gradually exhausts, and kidney yin is just seen deficiency, and sun loses hiding.
The kidney being the origin of congenital constitution, the root of vigour, and main store essential substances, interior residence nephroyin and nephroyang, basic for the whole body yang-energy, cloudy liquid, the kidney qi prosperity and decline is concerning variations such as the growth, reproduction, decline of human body.With advancing age, women's kidney qi arrives by containing degradation and exhausts, and dashes and appoints loss, and menses gradually exhausts, the imbalance of YIN and YANG of kidney.Because the kidney yin kidney yang is the body root of YIN and YANG, itself in case occur not enough, must cause whole body internal organs meridians lose in nourish, warm and functional disorder, so " suffering from a deficiency of the kidney " for this disease originally.Deficiency of kidney-essence, essence can not activating QI, so also decline more of kidney qi.Kidney is hidden the essence of five ZANG-organs and six FU-organs, suffers from a deficiency of the kidney that it is foster then the vital organs of the human body to be lost in moistening, and causes visceral dysfunction such as the heart, liver, spleen and sends out and be primary disease.
In the side: the Radix Rehmanniae, Radix Rehmanniae Preparata, Cortex Lycii, Radix Arnebiae (Radix Lithospermi), Herba Ecliptae, Fructus Corni, Fructus Ligustri Lucidi, Herba Dendrobii, Radix Ophiopogonis, Rhizoma Polygonati Odorati YIN nourishing and the production of body fluid promoting, clearing away heat and cooling blood, vital essence replenishing and marrow benifiting.Fructus Ligustri Lucidi, cool in nature, bitter but sweet flavor, liver and kidney tonifying; Existing estrogen-like product in the Fructus Ligustri Lucidi also has the material of androgenic to exist, and promptly same medicine has dual regulation.Test the large follicle of the rabbit ovary that shows one group of clothes Fructus Ligustri Lucidi and count showed increased, estrogen raises.Herba Ecliptae, cold in nature, sweet in the mouth acid, the merit of tool the kidney invigorating tonifying YIN, Compendium of Material Medica " black moustache is sent out, and kidney tonifying is cloudy ", modern medicine study confirms the raising immunologic function is arranged, coronary blood flow increasing and sedation.Radix Arnebiae (Radix Lithospermi), bitter in the mouth is cold, and GUIXIN Liver Channel, " Bencao Jingshu " are claimed its " for the key medicine of removing heat from blood ", and " medical center usurp will " be said can " reinforcing the heart be delayed liver, dissipating blood stasis, removing heat from blood ".Prove that according to modern pharmacological research Radix Arnebiae (Radix Lithospermi) has the effect of anti-pituitary gonadotropic hormone and chorionic-gonadotropin hormone.Colla Plastri Testudinis, Colla carapax Trionycis kidney tonifying nourish blood, nourishing YIN for suppressing the hyperactive YANG.Cortex Albiziae, Cortex et Radix Polygalae (processed), Semen Ziziphi Spinosae, Semen Platycladi, Fructus Tritici Levis mind tranquilizing and the heart calming, resolving depression heat extraction are held concurrently with arresting sweating.Fructus Tritici Levis, sweet in the mouth is cool in nature, Compendium of Material Medica " the QI invigorating heat extraction ends spontaneous sweating, hectic fever due to YIN-deficiency consumptive fever, married woman's consumptive fever ".Pericarpium Citri Reticulatae, Flos Rosae Rugosae, Radix Salviae Miltiorrhizae regulating the flow of QI to alleviate depression, nourishing blood to tranquillize the mind.Radix Glycyrrhizae Preparata, the invigorating middle warmer of Mel QI invigorating, coordinating the actions of various ingredients in a prescription.Semen sojae atricolor, Compendium of Material Medica is said: " bean has the five colors, each treating disorders in five ZANG-organs, it is cold that the thought Semen sojae atricolor belongs to aqueous, can go into kidney ".Research shows that the osajin composition in the Semen sojae atricolor has clear and definite estrogen-like effects, is used to treat climacteric syndrome.Yellow wine has promoting blood circulation, and the intestines and stomach, is supported board gas, held up therapeutical effect such as liver at profit skin, can remove the smell of mutton of animal glue class simultaneously.All medicines are made a concerted effort, Heibei provincial opera negative and positive, YIN nourishing and not hinder stomach to be given birth to wet, heat clearing away and bitter cold too not.
As a kind of traditional Chinese medicines dosage form, embodied the wholistic therapy idea of traditional medicine, patient's whole body is nursed one's health comprehensively.And can dialectically combine with differential diagnosis of diseases, with strong points.Need not when taking to decoct, portable is prone to deposit, and taste is pleasant, and the efficacy of a drug relaxes, stable and durable, and the four seasons are suitable.
Through clinical use: the treatment group is taken the three locations YIN nourishing and is transferred towards cream.Matched group is taken GENGNIANAN PIAN.Treatment group total effective rate is compared with matched group more than 97.00%, and difference has significance (P < 0.05); Treatment group Syndrome in TCM marquis total effective rate 98.00% is compared with matched group, and difference has significance (P < 0.05).Treatment back Kupperman integration and all significantly reductions of tcm symptom integration (P < 0.01) are compared with matched group, and difference has significance (P < 0.01); Each individual event symptom of the traditional Chinese medical science is obviously improved, and compares with matched group, and difference has significance (P < 0.05); Each item Clinical detection index is obviously improved (P < 0.01), compares with matched group, and difference has significance (P < 0.01).
The specific embodiment:
The present invention is that a kind of three locations YIN nourishing of treating perimenopausal syndrome is transferred towards cream.Its raw material is formed:
The Radix Rehmanniae 240~270g Radix Rehmanniae Preparata 240~270g Cortex Lycii 240~270g Radix Arnebiae (Radix Lithospermi) 240~270g
Herba Ecliptae 240~270g Fructus Ligustri Lucidi 240~270g Colla Plastri Testudinis 240~270g
Colla carapax Trionycis 240~270g Fructus Corni 130~160g Cortex Albiziae 130~160g
Cortex et Radix Polygalae (processed) 130~160g Herba Dendrobii 240~270g 240~270g Radix Ophiopogonis Rhizoma Polygonati Odorati 240~270g
Pericarpium Citri Reticulatae 80~120g Flos Rosae Rugosae 80~120g Semen Ziziphi Spinosae 240~270g Semen Platycladi 180~220g Radix Salviae Miltiorrhizae 240~270g Fructus Tritici Levis 480~520g Radix Glycyrrhizae Preparata 80~120g Semen sojae atricolor 480~520g Mel 480~520g yellow wine 500ml.
Instructions of taking: every day 2 times, each 20g; Boiled water is taken after mixing with liquid.
Method for making: above 20 four Chinese medicine things, wherein Colla Plastri Testudinis, Colla carapax Trionycis add yellow wine and dissolve, and Mel is subsequent use, and 20 flavors such as all the other Radix Rehmanniae were soaked 1 hour; Decoct secondary, each 2 hours, filter, merging filtrate left standstill 24 hours; Getting supernatant concentration to relative density is the clear paste of 1.10~1.20 (50~55 ℃), adds Mel, boils, and filters; The dissolving liquid of filtrating and Colla Plastri Testudinis, Colla carapax Trionycis and yellow wine is concentrated into the relative density of regulation, makes 1000g, promptly gets.
Clinical operating position:
Collect 200 routine patients altogether as observing case.Be divided into treatment group and matched group at random, every group of each 100 routine patient, the treatment group is taken the three locations YIN nourishing and is transferred towards cream.Matched group is taken GENGNIANAN PIAN.
Serveing on for 4 weeks is a course of treatment, treats three courses of treatment continuously.
According to clinical symptoms improvement Kupperman standards of grading and tcm syndrome curative effect determinate standard, judge clinical efficacy.
People's Republic of China's traditional Chinese medical science industry standard that the tcm symptom standards of grading were implemented with reference to nineteen ninety-five " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " is formulated.
The treatment group is evident in efficacy, and wherein the clinical efficacy cure rate 45.00%, obvious effective rate 36.00%, and effective percentage 16.00%, total effective rate 97.00% is compared with matched group, and difference has significance (P < 0.05); Treatment group Syndrome in TCM marquis curative effect cure rate 44.00%, obvious effective rate 37.00%, effective percentage 17.00%, total effective rate 98.00% is compared with matched group, and difference has significance (P < 0.05).Treatment back Kupperman integration and all significantly reductions of tcm symptom integration (P < 0.01) are compared with matched group, and difference has significance (P < 0.01); Each individual event symptom of the traditional Chinese medical science is obviously improved, and compares with matched group, and difference has significance (P < 0.05); Each item Clinical detection index is obviously improved (P < 0.01), compares with matched group, and difference has significance (P < 0.01).
Therefore, the present invention has and can nurse one's health patient's whole body comprehensively, and is with strong points, evident in efficacy; Need not when taking to decoct, portable is prone to deposit, and taste is pleasant, and the efficacy of a drug relaxes, stable and durable, characteristics such as the four seasons are suitable.
Claims (1)
1. a treatment climacteric is comprehensive
DiseaseThe three locations YIN nourishing transfer towards cream, it is characterized in that: raw material is formed and by its weight ratio is:
The Radix Rehmanniae 240~270g Radix Rehmanniae Preparata 240~270g Cortex Lycii 240~270g Radix Arnebiae (Radix Lithospermi) 240~270g
Herba Ecliptae 240~270g Fructus Ligustri Lucidi 240~270g Colla Plastri Testudinis 240~270g
Colla carapax Trionycis 240~270g Fructus Corni 130~160g Cortex Albiziae 130~160g
Cortex et Radix Polygalae (processed) 130~160g Herba Dendrobii 240~270g 240~270g Radix Ophiopogonis Rhizoma Polygonati Odorati 240~270g
Pericarpium Citri Reticulatae 80~120g Flos Rosae Rugosae 80~120g Semen Ziziphi Spinosae 240~270g Semen Platycladi 180~220g Radix Salviae Miltiorrhizae 240~270g Fructus Tritici Levis 480~520g Radix Glycyrrhizae Preparata 80~120g Semen sojae atricolor 480~520g
Mel 480~520g yellow wine 500ml.
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CN104107336A (en) * | 2014-07-30 | 2014-10-22 | 马振芹 | Traditional Chinese medicament for treating amenorrhea-galactorrhea syndrome and preparation method of traditional Chinese medicament |
CN105194521A (en) * | 2015-11-09 | 2015-12-30 | 陈慧珊 | Traditional Chinese medicine oral liquid for relieving premature ovarian failure and preparation method thereof |
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CN1806840A (en) * | 2005-01-21 | 2006-07-26 | 中国科学院上海药物研究所 | Chinese medicinal compound preparation and its preparing process |
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CN1806840A (en) * | 2005-01-21 | 2006-07-26 | 中国科学院上海药物研究所 | Chinese medicinal compound preparation and its preparing process |
Non-Patent Citations (1)
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山东省淄博市古方中医疑难病研究所: "《古方中医网》", 1 May 2001 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104107336A (en) * | 2014-07-30 | 2014-10-22 | 马振芹 | Traditional Chinese medicament for treating amenorrhea-galactorrhea syndrome and preparation method of traditional Chinese medicament |
CN105194521A (en) * | 2015-11-09 | 2015-12-30 | 陈慧珊 | Traditional Chinese medicine oral liquid for relieving premature ovarian failure and preparation method thereof |
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Application publication date: 20120704 |