CN102512652B - Medicinal composition for treating peptic ulcer - Google Patents

Medicinal composition for treating peptic ulcer Download PDF

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Publication number
CN102512652B
CN102512652B CN 201210005612 CN201210005612A CN102512652B CN 102512652 B CN102512652 B CN 102512652B CN 201210005612 CN201210005612 CN 201210005612 CN 201210005612 A CN201210005612 A CN 201210005612A CN 102512652 B CN102512652 B CN 102512652B
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CN
China
Prior art keywords
parts
peptic ulcer
rhizoma
medicinal composition
radix
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Expired - Fee Related
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CN 201210005612
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Chinese (zh)
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CN102512652A (en
Inventor
宋学平
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Yueyang Pengcheng Technology Development Co Ltd
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Individual
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Abstract

Te invention relates to a medicinal composition for treating peptic ulcer. The medicinal composition is a preparation which is prepared from the following raw material medicines in parts by weight: 1-10 parts of dwarf lilyturf root, 1-10 parts of inula flower, 1-5 parts of rhubarb, 1-5 parts of pinellia tuber, 1-5 parts of ginger, 1-5 parts of tuckahoe, 1-20 parts of clematis root, 1-10 parts of corydalis tuber and 1-10 parts of gallnut. The medicinal composition provided by the invention has a rational prescription and a clear curative effect, can be used for effectively treating the peptic ulcer and has the advantages of preventing and treating the effect of the peptic ulcer, along with no adverse reaction and low price.

Description

A kind of pharmaceutical composition for the treatment of peptic ulcer
Technical field
The present invention relates to field of medicaments, specifically, relate to a kind of pharmaceutical composition for the treatment of peptic ulcer.
Background technology
Adopt clinically H 2The short term effect of receptor antagonist treatment peptic ulcer gains public acceptance, but owing to can not continue to take medicine to the serious order of hepatic and renal function injure, therefore still have the patient about 20% need change his method treatment, the little medicine of side effect seems very necessary so select good effect clinically.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition for the treatment of peptic ulcer.
In order to realize purpose of the present invention, the invention provides a kind of pharmaceutical composition for the treatment of peptic ulcer, it is the medicament of being made by weight by following bulk drugs: 1~10 part of 1~10 part of Radix Ophiopogonis, 1~10 part of Flos Inulae, 1~5 part of Radix Et Rhizoma Rhei, 1~5 part of the Rhizoma Pinelliae, 1~5 part in Rhizoma Zingiberis Recens, 1~5 part in Poria, 1~20 part of Radix Clematidis, 1~10 part of Rhizoma Corydalis and Galla Chinensis.
Preferably, it is the medicament of being made by weight by following bulk drugs: 6 parts of 5 parts of Radix Ophiopogonis, 5 parts of Flos Inulae, 3 parts of Radix Et Rhizoma Rhei, 3 parts of the Rhizoma Pinelliaes, 2 parts in Rhizoma Zingiberis Recens, 2 parts in Poria, 15 parts of Radix Clematidis, 6 parts of Rhizoma Corydalis and Galla Chinensiss.
Pharmaceutical composition of the present invention can be made various dosage forms with pharmaceutically acceptable carrier, such as tablet, dispersible tablet, buccal tablet, capsule, pill, granule, powder or decoction etc.Can adopt preparation technique means well known in the art to finish the preparation of pharmaceutical composition of the present invention.
Described pharmaceutically acceptable carrier is well known, is usual excipients or the adjuvant for the preparation of above-mentioned preparation.Excipient or adjuvant commonly used comprise (but being not limited to) filler, lubricant, dispersant, wetting agent, binding agent, antioxidant etc., for example, syrup, arabic gum, sorbitol, lactose, dextrin, starch, calcium carbonate, Pulvis Talci, Polyethylene Glycol, carboxymethyl starch sodium, magnesium stearate etc.
The reasonable recipe of pharmaceutical composition of the present invention, curative effect is clear and definite, can effectively treat peptic ulcer, have the prevention and the treatment peptic ulcer effect, have no adverse reaction, low-cost advantage.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 medicinal composition tablets of the present invention
Take by weighing gram Radix Ophiopogonis 50, Flos Inulae 50 grams, Radix Et Rhizoma Rhei 30 grams, the Rhizoma Pinelliae 30 grams, Rhizoma Zingiberis Recens 20 grams, Poria 20 grams, Radix Clematidis 150 grams, Rhizoma Corydalis 60 grams and Galla Chinensis 60 grams, chopping, the water of 12 times of crude drug weight of adding, 100 ℃ of heating decocted 3 hours, filter, collect filtrate.It is 1.4 (50 ℃) thick paste that filtrate is concentrated into relative density, and drying is pulverized, add microcrystalline Cellulose 150 grams, mannitol 60 grams, carboxymethyl starch sodium 20 grams, mixing adds the amidin soft material processed of 8% (w/w), granulate, make 200 in tablet.
Experimental example
Diagnostic criteria:
All cases are all diagnosed about the diagnostic criteria of peptic ulcer with reference to the higher medical institution teaching material " internal medicine " of People's Health Publisher's publication in 1996.Its clinical manifestation has that the upper abdomen stomach headquarters or seat of leading organs of an institute like the Chinese Academy of Sciences is painful to be disclosed, nausea and vomiting, and heating installation pantothenic acid, inappetence, abdominal distention etc., the visible activeness ulcer of gastroscopy focus exists, and checks the epigastrium pain that the pathological changes of internal organs such as getting rid of livers, gallbladder, pancreas causes through other.
Close case 50 examples of the standard of stating of selector, male's 25 examples wherein, 38.7 years old mean age, women's 25 examples, 34.2 years old mean age.
Therapeutic scheme
Use the tablet of preparation among the embodiment 1 to treat, one day three times, each two, treating continuously seven days is a course for the treatment of.
Efficacy assessment standard
The criterion of therapeutical effect of " the clinical common disease diagnosis and treatment standard " of publishing with reference to Beijing Medical University in 1993, combined publication society of China Concord Medical Science University is drafted.Cure: sings and symptoms disappears, and gastroscope check ulcer healing enters cicatricial phase; Take a turn for the better: sings and symptoms obviously alleviates or substantially disappears, and gastroscope check ulcer is dwindled more than 1/2 the attenuation of tongue film; Invalid: sings and symptoms is without improvement, and gastroscope check ulcer is not dwindled or is front enlarger.
Therapeutic outcome:
Through the treatment of a course for the treatment of, whole 50 routine patients all meet the standard of healing.
Untoward reaction
In therapeutic process, do not find obvious untoward reaction.

Claims (2)

1. pharmaceutical composition for the treatment of peptic ulcer, it is characterized in that it is the medicament of being made by weight by following bulk drugs: 1~10 part of 1~10 part of Radix Ophiopogonis, 1~10 part of Flos Inulae, 1~5 part of Radix Et Rhizoma Rhei, 1~5 part of the Rhizoma Pinelliae, 1~5 part in Rhizoma Zingiberis Recens, 1~5 part in Poria, 1~20 part of Radix Clematidis, 1~10 part of Rhizoma Corydalis and Galla Chinensis.
2. the pharmaceutical composition for the treatment of peptic ulcer according to claim 1, it is characterized in that it is the medicament of being made by weight by following bulk drugs: 6 parts of 5 parts of Radix Ophiopogonis, 5 parts of Flos Inulae, 3 parts of Radix Et Rhizoma Rhei, 3 parts of the Rhizoma Pinelliaes, 2 parts in Rhizoma Zingiberis Recens, 2 parts in Poria, 15 parts of Radix Clematidis, 6 parts of Rhizoma Corydalis and Galla Chinensiss.
CN 201210005612 2012-01-10 2012-01-10 Medicinal composition for treating peptic ulcer Expired - Fee Related CN102512652B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201210005612 CN102512652B (en) 2012-01-10 2012-01-10 Medicinal composition for treating peptic ulcer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201210005612 CN102512652B (en) 2012-01-10 2012-01-10 Medicinal composition for treating peptic ulcer

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CN102512652A CN102512652A (en) 2012-06-27
CN102512652B true CN102512652B (en) 2013-03-13

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105617085A (en) * 2015-12-23 2016-06-01 高长忠 Composition for treating peptic ulcer and preparation method thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
中医药治疗消化性溃疡研究近况;贺俭;《中医药信息》;19981231(第4期);14-16 *
吴连恩等.自拟合欢愈疡汤治疗消化性溃疡108例.《河北中医》.1999,第21卷(第5期),271-272.
自拟合欢愈疡汤治疗消化性溃疡108例;吴连恩等;《河北中医》;19990930;第21卷(第5期);270-271 *
贺俭.中医药治疗消化性溃疡研究近况.《中医药信息》.1998,(第4期),14-16.

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Owner name: TIANJIANG PHARMACEUTICAL INDUSTRY CO., LTD., JIANG

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Address after: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8

Patentee after: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin

Address before: 272100 Department of Gastroenterology, Yanzhou people's Hospital, 1 health Road, Shandong, Yanzhou, China

Patentee before: Song Xueping

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Inventor after: Li Peng

Inventor before: Song Xueping

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Effective date of registration: 20170425

Address after: 414000 Yunxi Industrial Park, Yunxi District, Hunan, Yueyang

Patentee after: Yueyang Pengcheng Technology Development Co., Ltd.

Address before: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8

Patentee before: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130313

Termination date: 20180110