CN102205086A - Chinese medicinal composition for treating gastric and duodenal ulcer and preparation method thereof - Google Patents
Chinese medicinal composition for treating gastric and duodenal ulcer and preparation method thereof Download PDFInfo
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- CN102205086A CN102205086A CN2011101324004A CN201110132400A CN102205086A CN 102205086 A CN102205086 A CN 102205086A CN 2011101324004 A CN2011101324004 A CN 2011101324004A CN 201110132400 A CN201110132400 A CN 201110132400A CN 102205086 A CN102205086 A CN 102205086A
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Abstract
The invention relates to the field of traditional Chinese medicines, in particular to a Chinese medicinal composition for treating gastric and duodenal ulcer. The Chinese medicinal composition contains the following components in parts by weight: 12-20 parts of angelica dahurica, 15-20 parts of bletilla striata, 12-15 parts of atractylis ovate, 3-5 parts of roud cardamon seed, 12-15 parts of baikal skullcap root, 12-15 parts of phellodendron amurense, 15-20 parts of cuttlebone, 15-20 parts of rhizoma cyperi, 15-20 parts of rhizoma corydalis, 3-5 parts of asarum and 12-15 parts of Chinese date. The Chinese medicinal composition has the effects of harmonizing stomach, invigorating the spleen, regulating qi to alleviate pain, relieving hyperacidity, stopping bleeding, resisting inflammation forcibly, restoring ulcer, relieving pain and promoting gastric motility. Symptoms are eliminated by 5-15 doses in 60 patients, and 41 patients are cured by 25-45 doses. The Chinese medicinal composition is completely effective on 42 patients, excellent on 12 patients and effective on 6 patients, and has the total effective rate of100 percent.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly be used for the treatment of Chinese medicine composition of gastric and duodenal ulcers and preparation method thereof.
Background technology
Gastric and duodenal ulcers is gastral commonly encountered diseases, this disease is commonly considered as because after the pessimal stimulation in the cerebral cortex acceptance external world, cause harmonization of the stomach duodenum parietal vessel and muscle generation spasm, the resistance of gastrointestinal wall cytotrophy generation obstacle and gastrointestinal mucosa is reduced, cause gastrointestinal mucosa to be subject to gastric juice digestion and formation ulcer; Also the someone thinks due to the cyrtosis bacillus infection.Ulcer is single property often, but a plurality of ulcer are also arranged, and the harmonization of the stomach duodenal bulbar ulcer claims plyability ulcer when existing simultaneously.
The main clinical manifestation of duodenal ulcer is an epigastrium pain, can be dull pain, causalgia, distending pain or severe pain, also can show as only dull pain discomfort when hunger.Typical case person shows as rest pain under slight or the moderate xiphoid-process, can be alleviated by antacid or feed.Have 2/3 pain to be rhythmicity clinically approximately: early 1-3 hour after the meal begins to occur upper abdominal pain, then will continue to just alleviation after the lunch as not taking medicine or taking food.Also must have meal and alleviate in the food back in 2-4 hour again bitterly.About half patient has the pain at midnight, and patient often can be awake bitterly.Rhythmicity pain continues several weeks mostly, along with alleviating the several months, can take place repeatedly.
A kind of Chinese medicine composition is disclosed in " " soup of more bursting " treatment gastroduodenal ulcer 40 routine observation of curative effect " literary composition, by Radix Astragali 30g, Radix Codonopsis 15g, Rhizoma Atractylodis Macrocephalae 10g, Ramulus Cinnamomi 10g, Radix Glycyrrhizae 6g, Os Sepiae 15g, Bulbus Fritillariae Thunbergii 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g, Colla Corii Asini 10g, Rhizoma Corydalis 10g, Radix Notoginseng powder 3g, Cacumen Platycladi 30g forms.The effect of full side is that negative and positive of qi and blood develops simultaneously, Wen Tong with restrain mutually 5, the merit of playing replenishing QI to invigorate the spleen, promoting tissue regeneration and ulcer healing, dredging collateral to stop pain altogether.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition, said composition has powerful antiinflammatory, repairing ulcer, analgesia, hemostasis, the effect of stomach motility enhancing.
For achieving the above object, technical scheme of the present invention is:
Chinese medicine composition, composed of the following components by weight:
12 ~ 20 parts of the Radixs Angelicae Dahuricae
15 ~ 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s
12 ~ 15 parts of the Rhizoma Atractylodis Macrocephalaes
3 ~ 5 parts of Fructus Amomi Rotundus
12 ~ 15 parts of Radix Scutellariaes
12 ~ 15 parts of Cortex Phellodendris
15 ~ 20 parts of sea Octopus ocellatus Gray
15 ~ 20 parts of Rhizoma Cyperis
15 ~ 20 parts of Rhizoma Corydalis
3 ~ 5 parts of Herba Asaris
12 ~ 15 parts in Fructus Jujubae.
Further, described Chinese medicine composition, composed of the following components by weight:
17 parts of the Radixs Angelicae Dahuricae
18 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s
13 parts of the Rhizoma Atractylodis Macrocephalaes
4 parts of Fructus Amomi Rotunduss
13 parts of Radix Scutellariaes
14 parts of Cortex Phellodendris
18 parts of Endoconcha Sepiaes
18 parts of Rhizoma Cyperis
17 parts of Rhizoma Corydalis
4 parts of Herba Asaris
13 parts in Fructus Jujubae.
Further, described compositions is an oral formulations.
Further, described compositions decoction liquor, extractum or capsule.
Two of purpose of the present invention is to provide the preparation method of what thing of two kinds of Chinese medicines, and this manufacture method is simple to operate, is applicable to large-scale production.
For achieving the above object, technical scheme of the present invention is:
The preparation method of described Chinese medicine composition with each component porphyrize of Chinese medicine composition and after mixing in proportion, is made capsule in the capsulae vacuus of packing into.
Another kind of technical scheme is:
The preparation method of described Chinese medicine composition with each component porphyrize of Chinese medicine composition and after mixing in proportion, decocts with water 1-3 time, each 30-120 minute, decoction liquor.
Further, after described decoction liquor is concentrated extractum.
Three of purpose of the present invention is to provide a kind of new application of Chinese medicine composition, and this is applied as the treatment gastric and duodenal ulcers new approaches are provided.
For achieving the above object, technical scheme of the present invention is:
Described Chinese medicine composition is used for the treatment of application in the medicine of gastric and duodenal ulcers in preparation.
Beneficial effect of the present invention is: the spleen invigorating of this Chinese medicine composition stomach function regulating, the analgesia of regulating the flow of vital energy, antacid hemostasis.Modern pharmacology shows, the Radix Angelicae Dahuricae, Radix Scutellariae, Cortex Phellodendri broad-spectrum antiseptic and antiinflammatory, the Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae repairing ulcer, Fructus Amomi Rotundus stomach motility enhancing, the Radix Angelicae Dahuricae, Rhizoma Corydalis, Fructus Amomi Rotundus, Herba Asari, Rhizoma Cyperi powerful pain-stopping.Comprehensively above-mentioned, this compositions has powerful antiinflammatory, repairing ulcer, analgesia, hemostasis, the effect of stomach motility enhancing.
60 examples are all eliminated symptom, 25-45 doses of recoveries from illness of 41 examples at 5-15 doses.42 examples of fully recovering, produce effects 12
Example, effective 6 examples.Total effective rate 100%.
The specific embodiment
The preparation and the use of embodiment 1 Chinese medicine composition
Prescription 1: Chinese medicine composition, composed of the following components: Radix Angelicae Dahuricae 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Rhizoma Atractylodis Macrocephalae 12g, Fructus Amomi Rotundus 3g, Radix Scutellariae 12g, Cortex Phellodendri 12g, Endoconcha Sepiae 20g, Rhizoma Cyperi 20g, Rhizoma Corydalis 20g, Herba Asari 5g, Fructus Jujubae 15g.With each component porphyrize of described Chinese medicine composition and after mixing in proportion, make capsule in the capsulae vacuus of packing into, be potion, after every day, potion was eliminated to the gastric and duodenal ulcers symptom, change per two days potions into.
Prescription 2: Chinese medicine composition, composed of the following components: Radix Angelicae Dahuricae 20g, Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Rhizoma Atractylodis Macrocephalae 15g, Fructus Amomi Rotundus 5g, Radix Scutellariae 15g, Cortex Phellodendri 15g, Endoconcha Sepiae 15g, Rhizoma Cyperi 15g, Rhizoma Corydalis 15g, Herba Asari 3g, Fructus Jujubae 12g.With each component porphyrize of described Chinese medicine composition and after mixing in proportion, decoct with water 1 time, 120 minutes, the potion decoction liquor.Potion unboiled water on the one decoction, three fry in shallow oil mixing divides clothes three times; After the gastric and duodenal ulcers symptom is eliminated, potion on the two.
Prescription 3: described Chinese medicine composition, composed of the following components: Radix Angelicae Dahuricae 17g, Pseudobulbus Bletillae (Rhizoma Bletillae) 18g, Rhizoma Atractylodis Macrocephalae 13g, Fructus Amomi Rotundus 4g, Radix Scutellariae 13g, Cortex Phellodendri 14g, Endoconcha Sepiae 18g, Rhizoma Cyperi 18g, Rhizoma Corydalis 17g, Herba Asari 4g, Fructus Jujubae 13g.With each component porphyrize of described Chinese medicine composition and after mixing in proportion, decoct with water 3 times, each 30 minutes, merge decoction liquor and concentrate, potion extractum.After every day, potion was eliminated to the gastric and duodenal ulcers symptom, change per two days potions into.
The application of embodiment 2 Chinese medicine compositions in preparation treatment gastric and duodenal ulcers medicine
Clinical data
In recent years observe the gastric and duodenal ulcers that 60 examples are made a definite diagnosis through the barium agent of X line or gastroscopy.Man's 36 examples,
Woman's 24 examples; Minimum 19 years old of mean age, maximum 56 years old, average 35 years old; The course of disease is the shortest 9 months, and is the longest 24 months; Gastric ulcer 23 examples, duodenal ulcer 37 examples, companion's upper gastrointestinal hemorrhage 9 examples, pyloric obstruction 1 example.Cardinal symptom: Upper abdominal pain or " heartburn " sense, alleviate after meal, or acid regurgitation, 2 example is asymptomatic finds that because of melena 1 example is fallen in a swoon because of anemia and found.
Criterion of therapeutical effect
Symptomatology is eliminated, and do not recur more than 12 months, or the agent of X line barium, the no abnormal person of gastroscopy is for fullying recover from an illness
More; Symptomatology is eliminated, and does not recur more than 6 months, is produce effects; Full symptom is eliminated, and does not recur more than 3 months for effectively; 10 doses of symptoms are not eliminated to invalid.
Therapeutic effect
60 examples are all eliminated symptom, 25-45 doses of recoveries from illness of 41 examples at 5-15 doses.42 examples of fully recovering, produce effects 12
Example, effective 6 examples.Total effective rate 100%
The prescription effect
The stomach infections must the spleen invigorating of Kang Fang stomach function regulating, the analgesia of regulating the flow of vital energy, antacid hemostasis.Modern pharmacology shows, the Radix Angelicae Dahuricae, Radix Scutellariae,
Cortex Phellodendri broad-spectrum antiseptic and antiinflammatory, the Pseudobulbus Bletillae (Rhizoma Bletillae), Endoconcha Sepiae repairing ulcer, Fructus Amomi Rotundus stomach motility enhancing, the Radix Angelicae Dahuricae, Rhizoma Corydalis, Fructus Amomi Rotundus, Herba Asari, Rhizoma Cyperi powerful pain-stopping.Comprehensively above-mentioned, the present invention has powerful antiinflammatory, repairing ulcer, analgesia, hemostasis, the effect of stomach motility enhancing.
The no any untoward reaction of clinical observation we.
Subordinate list is lifted 6 examples for the gastric and duodenal ulcers of making a definite diagnosis through the barium agent of X line or gastroscopy and is listed as follows:
| Name | Sex | Age | The course of disease (moon) | Upper abdominal pain | It is heartburn to starve the back | Alleviate after meal | Have blood in stool | Hematemesis | Symptom is eliminated (agent) | The total agent number (agent) of fully recovering |
| King * gives birth to | The man | 19 | 9 | + | - | + | ++ | ++ | 15 | 35 |
| The virtuous * of section | The man | 56 | 30 | + | + | + | + | - | 10 | 45 |
| Liu Wen * | The man | 25 | 18 | ++ | + | + | - | - | 5 | 25 |
| Ran Miao * | The woman | 21 | 12 | ++ | + | + | - | - | 5 | 25 |
| Xu Sheng * | The man | 38 | Unknown | - | - | - | ++ | - | 10 | 30 |
| Yang De * | The woman | 43 | 24 | ++ | + | + | - | - | 5 | 25 |
In the table, "+" indicates slight, and " ++ " indicates severe, and "-" indicates not to be had
Explanation is at last, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although by invention has been described with reference to the preferred embodiments of the present invention, but those of ordinary skill in the art is to be understood that, can make various changes to it in the form and details, and the spirit and scope of the present invention that do not depart from appended claims and limited.
Claims (8)
1. Chinese medicine composition is characterized in that, and is composed of the following components by weight:
12 ~ 20 parts of the Radixs Angelicae Dahuricae
15 ~ 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s
12 ~ 15 parts of the Rhizoma Atractylodis Macrocephalaes
3 ~ 5 parts of Fructus Amomi Rotunduss
12 ~ 15 parts of Radix Scutellariaes
12 ~ 15 parts of Cortex Phellodendris
15 ~ 20 parts of Endoconcha Sepiaes
15 ~ 20 parts of Rhizoma Cyperis
15 ~ 20 parts of Rhizoma Corydalis
3 ~ 5 parts of Herba Asaris
12 ~ 15 parts in Fructus Jujubae.
2. Chinese medicine composition according to claim 1 is characterized in that, and is composed of the following components by weight:
17 parts of the Radixs Angelicae Dahuricae
18 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s
13 parts of the Rhizoma Atractylodis Macrocephalaes
4 parts of Fructus Amomi Rotunduss
13 parts of Radix Scutellariaes
14 parts of Cortex Phellodendris
18 parts of Endoconcha Sepiaes
18 parts of Rhizoma Cyperis
17 parts of Rhizoma Corydalis
4 parts of Herba Asaris
13 parts in Fructus Jujubae.
3. Chinese medicine composition according to claim 1 is characterized in that: described compositions is an oral formulations.
4. Chinese medicine composition according to claim 3 is characterized in that: described compositions decoction liquor, extractum or capsule.
5. the preparation method of each described Chinese medicine composition of claim 1-4 is characterized in that: with each component porphyrize of Chinese medicine composition and after mixing in proportion, make capsule in the capsulae vacuus of packing into.
6. the preparation method of each described Chinese medicine composition of claim 1-4 is characterized in that: with each component porphyrize of Chinese medicine composition and after mixing in proportion, decoct with water 1-3 time, each 30-120 minute, decoction liquor.
7. the preparation method of Chinese medicine composition according to claim 6 is characterized in that: get extractum after described decoction liquor is concentrated.
8. each described Chinese medicine composition of claim 1-4 is used for the treatment of application in the medicine of gastric and duodenal ulcers in preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011101324004A CN102205086B (en) | 2011-05-23 | 2011-05-23 | Chinese medicinal composition for treating gastric and duodenal ulcer and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011101324004A CN102205086B (en) | 2011-05-23 | 2011-05-23 | Chinese medicinal composition for treating gastric and duodenal ulcer and preparation method thereof |
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| Publication Number | Publication Date |
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| CN102205086A true CN102205086A (en) | 2011-10-05 |
| CN102205086B CN102205086B (en) | 2013-01-23 |
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| CN2011101324004A Expired - Fee Related CN102205086B (en) | 2011-05-23 | 2011-05-23 | Chinese medicinal composition for treating gastric and duodenal ulcer and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106109956A (en) * | 2016-07-22 | 2016-11-16 | 雷兴业 | Chinese medicine composition for the treatment of gastritis, gastric ulcer and duodenal ulcer and preparation method thereof |
| CN106110013A (en) * | 2016-07-22 | 2016-11-16 | 铜陵宏正网络科技有限公司 | A kind of Chinese medicine decoction treating duodenal ulcer |
-
2011
- 2011-05-23 CN CN2011101324004A patent/CN102205086B/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| 康承君: "李家邦教授治疗消化性溃疡经验", 《湖南中医杂志》 * |
| 黄传萍: "运用活血化瘀法治疗疑难证探讨", 《内蒙古中医药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106109956A (en) * | 2016-07-22 | 2016-11-16 | 雷兴业 | Chinese medicine composition for the treatment of gastritis, gastric ulcer and duodenal ulcer and preparation method thereof |
| CN106110013A (en) * | 2016-07-22 | 2016-11-16 | 铜陵宏正网络科技有限公司 | A kind of Chinese medicine decoction treating duodenal ulcer |
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| Publication number | Publication date |
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| CN102205086B (en) | 2013-01-23 |
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