CN102488864B - Medicinal composition for treating herpes zoster - Google Patents
Medicinal composition for treating herpes zoster Download PDFInfo
- Publication number
- CN102488864B CN102488864B CN 201110407154 CN201110407154A CN102488864B CN 102488864 B CN102488864 B CN 102488864B CN 201110407154 CN201110407154 CN 201110407154 CN 201110407154 A CN201110407154 A CN 201110407154A CN 102488864 B CN102488864 B CN 102488864B
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- Prior art keywords
- weight portion
- weight
- radix
- herpes zoster
- flos
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 208000007514 Herpes zoster Diseases 0.000 title claims abstract description 18
- 239000000203 mixture Substances 0.000 title abstract description 9
- 241001092371 Bergenia Species 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims description 14
- 241000628997 Flos Species 0.000 claims description 9
- 229940079593 drug Drugs 0.000 claims description 8
- 239000008194 pharmaceutical composition Substances 0.000 claims description 8
- 230000000694 effects Effects 0.000 abstract description 7
- 241000173529 Aconitum napellus Species 0.000 abstract 1
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 241000510654 Bupleurum chinense Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 240000009138 Curcuma zedoaria Species 0.000 abstract 1
- 235000003405 Curcuma zedoaria Nutrition 0.000 abstract 1
- 241000096284 Gynochthodes officinalis Species 0.000 abstract 1
- 240000006079 Schisandra chinensis Species 0.000 abstract 1
- 235000008422 Schisandra chinensis Nutrition 0.000 abstract 1
- 241000246044 Sophora flavescens Species 0.000 abstract 1
- 244000297179 Syringa vulgaris Species 0.000 abstract 1
- 235000004338 Syringa vulgaris Nutrition 0.000 abstract 1
- 239000001812 curcuma zedoaria berg. rosc. Substances 0.000 abstract 1
- 235000019509 white turmeric Nutrition 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 206010054786 Skin burning sensation Diseases 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 235000009392 Vitis Nutrition 0.000 description 1
- 241000219095 Vitis Species 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000007919 dispersible tablet Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 150000002333 glycines Chemical class 0.000 description 1
- 239000007902 hard capsule Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 210000001937 intercostal nerve Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 206010034754 petechiae Diseases 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 206010040882 skin lesion Diseases 0.000 description 1
- 231100000444 skin lesion Toxicity 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a medicinal composition for treating herpes zoster. The medicinal composition is prepared from angelica sinensis, schisandra chinensis, bergenia, zedoary, morinda officinalis, lilac daphne flower bud, monkshood, trollflower, bupleurum chinense, sophora flavescens, rhizoma acori graminei, safflower, dried tangerine, fructus ligustri lucidi and rhizoma sparganii. The components of the medicinal composition for treating herpes zoster are obtained easily, and the medicinal composition for treating herpes zoster has an obvious curative effect, and does not have obvious side effects.
Description
Technical field
The present invention relates to field of medicaments, particularly, the present invention relates to a kind of pharmaceutical composition for the treatment of herpes zoster.
Background technology
Herpes zoster is a kind of dermatosis that is caused by virus, and any position of health can occur.Be apt to occur in the areal area of nervi trigeminus, nervi vertebralis, intercostal nerves and waist sacral nerves, because it invades nerve, patient's sufferings are in time treated particularly important unbearably.Herpes zoster belongs to " herpes zoster ", " skirt-roof dragon ", " Fructus Vitis viniferae stream " category.How because of feelings will internal injury, stagnation of QI due to depression of the liver, fire-transformation with the passing of time, the liver and gall fire is contained, and is subjected to poison evil and send out outward, and with purging liver and gallbladder, detoxification and promoting urination, reducing swelling and alleviating pain are the rule for the treatment of.These become the newtype drug basis of seeking the treatment herpes zoster.Finished on this basis the present invention.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition for the treatment of herpes zoster.
In order to realize purpose of the present invention, the invention provides a kind of pharmaceutical composition for the treatment of herpes zoster, it is the medicament of being made according to weight proportion by following bulk drugs:
Preferably, the pharmaceutical composition for the treatment of herpes zoster of the present invention is the medicament of being made according to weight proportion by following bulk drugs:
The pharmaceutical composition for the treatment of herpes zoster of the present invention can be made various dosage forms according to technological means well-known to those skilled in the art, such as tablet (dispersible tablet), capsule, hard capsule, decoction etc.
The drug regimen composition formula for the treatment of herpes zoster of the present invention is reasonable, and composition is simple and easy to, and is evident in efficacy, and do not have an obvious side effect.
The specific embodiment
The following examples will be further described the present invention, but not thereby limiting the invention.
Embodiment 1
Get Radix Angelicae Sinensis 500 grams, Fructus Schisandrae Chinensis 300 grams, Rhizoma Seu Herba Bergeniae 2000 grams, Radix Curcumae 500 grams, Radix Morindae Officinalis 2000 grams, Flos Genkwa 500 grams, Radix Aconiti Lateralis Preparata 300 grams, Flos Trollii 1000 grams, Radix Bupleuri 1500 grams, Radix Sophorae Flavescentis 300 grams, Rhizoma Acori Graminei 1500 grams, Flos Carthami 300 grams, Pericarpium Citri Reticulatae 1000 grams, Fructus Ligustri Lucidi 300 grams, rhizoma sparganic 300 grams, pulverizer is pulverized, cross 80 mesh sieves, add microcrystalline Cellulose 3000 grams, mannitol 1000 grams, mix homogeneously, amidin pelletize with 10 % by weight, dry rear and crospolyvinylpyrrolidone 500 gram mix homogeneously are pressed 1000.
Test example
Diagnostic criteria
Clinical diagnosis all meets the diagnostic criteria of " traditional Chinese medical science disease Standardization of diagnosis and curative effect " middle herpes zoster of State Administration of Traditional Chinese Medicine's issue.1. skin lesion mostly is the water scar of Semen phaseoli radiati or Semen Glycines size, assembles in threes and fours a place or many places, is arranged in band shape, and the substrate flushing is even the petechia can occur when serious, the blood scar is downright bad; 2. from the beginning of skin rubefaction, and companion's skin irritation or burning sensation, can be with slight heating, the General Symptomies such as tired discomfort, inappetence.Conscious pain is obvious, and unbearably severe pain and rear something lost pain symptom are arranged.
Choose patient's 40 examples that meet above-mentioned diagnostic criteria, wherein, male 20 examples, women 20 examples, the oldest person is 60 years old, reckling is 28 years old, average 41 years old.
Use the tablet of embodiment 1 preparation to treat every day 3 times, each 3.7 days courses for the treatment of.
The observation of curative effect standard
" Chinese medicine card Standardization of diagnosis and curative effect " with reference to State Administration of Traditional Chinese Medicine's issue drafted.Recovery from illness: deflorescence, clinical symptom disappearance is without the pain sequela; Take a turn for the better: deflorescence approximately 50%, pain obviously alleviates; Do not heal: deflorescence less than 30% still has the pain malaise symptoms.
Therapeutic outcome
After treatment course for the treatment of, all patients' curative effect all meets the standard of recovery from illness, and in therapeutic process without any untoward reaction.
Claims (2)
1. a pharmaceutical composition for the treatment of herpes zoster is characterized in that, it is the medicament of being made according to weight proportion by following bulk drugs:
Radix Angelicae Sinensis 1～10 weight portion Fructus Schisandrae Chinensis 1～5 weight portion Rhizoma Seu Herba Bergeniae 10～30 weight portions
Radix Curcumae 1～10 weight portion Radix Morindae Officinalis 10～30 weight portion Flos Genkwas 1～10 weight portion
Radix Aconiti Lateralis Preparata 1～5 weight portion Flos Trollii 5～15 weight portion Radix Bupleuri 10～20 weight portions
Radix Sophorae Flavescentis 1～5 weight portion Rhizoma Acori Graminei 10～20 weight portion Flos Carthamis 1～5 weight portion
Pericarpium Citri Reticulatae 5～15 weight portion Fructus Ligustri Lucidi 1～5 weight portion rhizoma sparganic 1～5 weight portion.
2. the pharmaceutical composition for the treatment of herpes zoster according to claim 1 is characterized in that, it is the medicament of being made according to weight proportion by following bulk drugs:
Radix Angelicae Sinensis 5 weight portion Fructus Schisandrae Chinensis 3 weight portion Rhizoma Seu Herba Bergeniaes 20 weight portions
Radix Curcumae 5 weight portion Radix Morindae Officinaliss 20 weight portion Flos Genkwas 5 weight portions
Radix Aconiti Lateralis Preparata 3 weight portion Flos Trolliis 10 weight portion Radix Bupleuri 15 weight portions
Radix Sophorae Flavescentis 3 weight portion Rhizoma Acori Graminei 15 weight portion Flos Carthamis 3 weight portions
Pericarpium Citri Reticulatae 10 weight portion Fructus Ligustri Lucidi 3 weight portion rhizoma sparganic 3 weight portions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110407154 CN102488864B (en) | 2011-12-09 | 2011-12-09 | Medicinal composition for treating herpes zoster |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110407154 CN102488864B (en) | 2011-12-09 | 2011-12-09 | Medicinal composition for treating herpes zoster |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102488864A CN102488864A (en) | 2012-06-13 |
| CN102488864B true CN102488864B (en) | 2013-05-01 |
Family
ID=46180759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110407154 Expired - Fee Related CN102488864B (en) | 2011-12-09 | 2011-12-09 | Medicinal composition for treating herpes zoster |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102488864B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105311416A (en) * | 2015-12-02 | 2016-02-10 | 卢雨萍 | Externally applied traditional Chinese medicine for treating herpes zoster |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129425A (en) * | 2007-09-21 | 2008-02-27 | 黄铨明 | Traditional Chinese medicine for treating zoster |
| CN102038788A (en) * | 2009-10-15 | 2011-05-04 | 张俊安 | Medicament for treating herpes zoster |
-
2011
- 2011-12-09 CN CN 201110407154 patent/CN102488864B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129425A (en) * | 2007-09-21 | 2008-02-27 | 黄铨明 | Traditional Chinese medicine for treating zoster |
| CN102038788A (en) * | 2009-10-15 | 2011-05-04 | 张俊安 | Medicament for treating herpes zoster |
Non-Patent Citations (2)
| Title |
|---|
| 带状疱疹中医药治疗研究进展;王一飞等;《江苏中医药》;20051005;第26卷(第10期);76-78 * |
| 王一飞等.带状疱疹中医药治疗研究进展.《江苏中医药》.2005,第26卷(第10期),76-78. |
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| Publication number | Publication date |
|---|---|
| CN102488864A (en) | 2012-06-13 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: TIANJIANG PHARMACEUTICAL INDUSTRY CO., LTD., JIANG Free format text: FORMER OWNER: ZHENG LIXIA Effective date: 20130808 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 272000 JINING, SHANDONG PROVINCE TO: 214400 WUXI, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20130808 Address after: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee after: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin Address before: 272000 infectious diseases office, first people's Hospital of Shandong, Jining Province, 6 health Road, Shandong, Jining Patentee before: Zheng Lixia |
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| CB03 | Change of inventor or designer information |
Inventor after: Li Peng Inventor before: Zheng Lixia |
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| CB03 | Change of inventor or designer information | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170411 Address after: 414000 Yunxi Industrial Park, Yunxi District, Hunan, Yueyang Patentee after: Yueyang Pengcheng Technology Development Co., Ltd. Address before: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee before: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin |
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| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130501 Termination date: 20171209 |
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| CF01 | Termination of patent right due to non-payment of annual fee |