CN102488768B - Traditional Chinese medicine for treating gout - Google Patents

Traditional Chinese medicine for treating gout Download PDF

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CN102488768B
CN102488768B CN201110409099.7A CN201110409099A CN102488768B CN 102488768 B CN102488768 B CN 102488768B CN 201110409099 A CN201110409099 A CN 201110409099A CN 102488768 B CN102488768 B CN 102488768B
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王宝香
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Abstract

The invention relates to a traditional Chinese medicine for treating gout, and the traditional Chinese medicine for treating gout is prepared from the following components: 12 grams of mulberry branches, 9 grams of caulis spatholobi, 9 grams of sarcandra glabra, 6 grams of radix clematidis, 9 grams of tetrapanax papyriferus, 9 grams of magnolia obavata, 9 grams of the root of three-nerved spicebush, 9 grams of rhizoma chuanxiong, 9 grams of roots of common peony, 6 grams of scorpio, 9 grams of lumbricus, 6 grams of notopterygium roots, 9 grams of lovage, 9 grams of salvia miltiorrhiza, 15 grams of selfheal, 6 grams of licorice roots, 6 grams of angelica dahurica, 9 grams of divaricate saposhnikovia roots, 6 grams of Rubia tinctorum Madder roots and 9 grams of asarum. The method for taking the medicine comprises the following steps: acquiring the medicine, adding water (1500 ml) into the medicine, decocting the obtained mixture for 45 minutes by using a slow fire, removing dregs in the mixture, and filtering the obtained product so as to obtain a decoction; and taking a dose of the decoction everyday, wherein 14 days are set as a period of treatment. By using the traditional Chinese medicine for treating gout, the pathogenesis can be fitted, and an effect of treating both principal and secondary aspects of a disease can be achieved; and meanwhile, the medicine is rich in medicinal herbs resource, low in price and less in side effect.

Description

The Chinese medicine for the treatment of gout
Technical field
The present invention relates to technical field of Chinese medicines, specifically treats the Chinese medicine of gout.
Background technology
Gout is that synthetic increase or the discharge of uric acid in human body reduces, and causes hyperuricemia, and during uric acid in blood excessive concentration, uric acid, along with the circulation of blood is deposited in joint, cartilage and kidney with the form of sodium salt, causes and organizes foreign body inflammatory reaction, i.e. gout.Due to uric acid excessive concentration in blood of human body, at soft tissue, form acicular crystal in as membrana articulata or tendon, cause health immune system overreaction and the inflammation that causes suffering.General gout outbreak position is thumb joint, ankle joint, knee joint etc.Long-term patient with gout has and shows effect in finger-joint, and even auricle is containing the case of soft tissue portion.Gouty attack,acute position occur red, swollen, hot, have an intense pain.At the gout initial stage, lower limb are more common in outbreak.The normal phase outbreak of gout can produce infringement to kidney.From gout pathogeny, treatment and prevent that gout from must control or reduce the concentration of uric acid in blood, prevents the crystallization of uric acid in joint or soft tissue, reduces clinically uric acid concentration and adopts Western medicine control more, uric acid is mainly by renal excretion, and long-term taking can damage kidney.The side effect for the treatment of by Chinese herbs gout is little, and therapeutic effect is stable, progressively by Most patients, is approved.
Summary of the invention
The object of the present invention is to provide one to treat gout effective, instant effect, the Chinese medicine that side effect is little.
Technical solution of the present invention: the Chinese medicine for the treatment of gout, formulated by following ingredients: 12 grams of Ramulus Moris, 9 grams of Caulis Spatholobis, 9 grams, Psychotria rubra (Lour.) Poir. maple, 6 grams of Radix Clematidis, 9 grams of Medulla Tetrapanaciss, 9 grams of Cortex Magnoliae Officinalis, 9 grams of the Radixs Linderae, 9 grams of Rhizoma Chuanxiongs, 9 grams of Radix Paeoniae Rubra, 6 grams of Scorpios, 9 grams of Pheretimas, 6 grams of Rhizoma Et Radix Notopterygiis, 9 grams of Radix Angelicae Pubescentiss, 9 grams of Radix Salviae Miltiorrhizaes, 15 grams of Spica Prunellaes, 6 grams, Radix Glycyrrhizae, 6 grams of the Radixs Angelicae Dahuricae, 9 grams of Radix Saposhnikoviaes, 6 grams of Radix Rubiae, 9 grams of Herba Asaris.Instructions of taking: get above-mentioned Chinese medicine, add water 1500ml, slow fire boiling 45 minutes, drags for slag filtration and make decoction; Every day potion, 14 days courses for the treatment of.
In the present invention's formula, each crude drug effect is as follows:
Ramulus Mori: wind-damp dispelling, sharp joint, row aqueous vapor.Control anemofrigid-damp arthralgia, spasm of the limbs, beriberi edema, human body pruritus due to wind pathogen.
Caulis Spatholobi: relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation.Main numb hand and foot; Quadriplegia; Rheumatic arthralgia; The modern Practical Chinese medicinal > of < < >: be the hematonic of robustness, be applicable to the neural paralysis disease of anemia, as limbs and soreness of waist and knee joint, apathetic etc.Again for menoxenia, menstruation apolipsis etc., have the effect of invigorating blood circulation analgesia.
Psychotria rubra (Lour.) Poir. maple: anti-inflammation, dispelling wind and removing obstruction in the collateral, blood circulation promoting and dispersing pathogen accumulation.For pneumonia, appendicitis, cellulitis, rheumatic arthralgia, traumatic injury, tumor.< < classification medical herbs > >: control all traumatic injury, rheumatic numbness, bones and muscles pain.
Radix Clematidis: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the loose hypochondriac lump.Cure mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, chills and pain of the waist and kness, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.
Medulla Tetrapanacis: clear snobbish water; Lactogenesis.The just > > of < < book on Chinese herbal medicine: this thing depletion of QI is tasteless, with light, act, the meridians therefore can pass through, clearing away heat and promoting diuresis, property is similar to Caulis Akebiae, but covers with mat without it, the power of drop-down is slow and without high strict fraud, though can tonneau, not impairment of YIN very, damp and hot not very person should it.If heat is very closed the disease of knot, can not and the victory effect of Caulis Akebiae, Dong Yuan calls sharp yin orifice, controls five types of stranguria, except edema infirmity, also light disease the being ear of gaining merit only.
Cortex Magnoliae Officinalis: have another name called Cortex Magnoliae Officinalis, energy circulation of qi promoting removing food stagnancy; Dampness is except full; Lowering the adverse QI to relieve asthma.Experiment showed, that Magnolol and Honokiol suppresses in all cases TXB2 and forms, in the cell being caused by arachidonic acid or collagen, Ca raises and also by both, is suppressed.The antiplatelet effects of Magnolol and Honokiol is due to the mobile inhibition of Ca in TXB2 and cell.
The Radix Linderae: promoting the circulation of QI to relieve pain, warming kidney for dispelling cold.The Radix Linderae has excitation to cardiac muscle, its volatile oil is for oral administration excited cardiac muscle, accelerate reflux cycle, boost and perspiration, also there is excited cerebral cortex, promote Repiration, local be coated with can distend the blood vessels, blood circulation quickening, alleviate the effect of compound muscle spasm pain.< < explaining abstruseness of the canon of materia medica > >: the pent-up of reason seven emotions, QI and blood is solidifying stops, and cholera is vomited and diarrhoea, and expectorant food is delaied.The beautiful Chinese catalpa medicine of < < solution > >: removing blood stasis with potent drugs is let out full, pain relieving relieving distension.
Rhizoma Chuanxiong: blood circulation promoting and blood stasis dispelling effect is extensive, the various diseases of suitable stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is the gas medicine in blood that former times people calls Rhizoma Chuanxiong, nearly says the functions such as pungent loose, the resolving depression of its residence, sensible, pain relieving.
Radix Paeoniae Rubra: clearing away heat and cooling blood, eliminating stasis to stop pain.Anti-thrombosis function, Radix Paeoniae Rubra decoct 15-20g (crude drug)/kg, to rat oral gavage, obviously extends thrombus formation time, contraction in length, weight saving; Prothrombin time and KPTT extend, and euglobulin lysis time shortens, and showing has remarkable inhibitory action to blood clotting.Antiplatelet aggregative activity, Radix Paeoniae Rubra extract all has remarkable inhibitory action to the platelet aggregation of epinephrine, adenosine diphosphate (ADP) (ADP), Trimeresurus (TMVA) and arachidonic acid (AA) induction in vitro, and making platelet adhesion and platelet factor III activity decreased, platelet intensive amount raises.The mechanism of Radix Paeoniae Rubra arteriosclerosis may with improve lipoprotein component ratio, reduce plasma lipid peroxide, reduce calcium be deposited on arterial wall, anticoagulant, regulates TXA2/PGI2 balance and activated adenyl cyclase and to increase in arterial wall concentration etc. relevant.
Scorpio: endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.< < Shandong Chinese herbal medicine handbook > >: endogenous wind stopping dredging collateral, spasmolytic.Control blood and fasten thromboangiitis obliterans, tuberculous lymphadenitis, tuberculosis of bone and joint, mumps.
Pheretima: current meridians, the available swollen swelling pain of pyretic arthralgia joint of controlling; Suitably compatibility also can be controlled arthralgia due to cold; Compatibility replenishing qi and promoting blood flow medicine is usually used in blood stasis due to qi deficiency, and meridians are unfavorable, hemiplegia aphasiac.Experimental results show that: Pheretima has the effect of thrombolytic and anticoagulant have and can obviously extend platelet thrombus and fibrinous thrombus formation time, thrombosis length and dry weight are reduced, and reduce blood viscosity.
Rhizoma Et Radix Notopterygii: diaphoretic medicine; Medicine for rheumatism.Control affection of exogenous wind-cold; Have a headache lossless; Mimeograph cold-damp numbness; Edema due to wind pathogen edema; Sore swollen toxin.。< < medicine origin > >: control arthrodynia of extremities, brothers' sun herbal classic wind medicine also.Add Rhizoma Chuanxiong and control the sufficient sun, SHAO YIN headache, saturating profit joint, the dispelling the wind and dampness pathogens again of closing.< < cures mainly secret formula > > cloud: it is with having five: brothers' sun tying-in, and one also; Rheumatism is held concurrently mutually, and two also; Remove arthrodynia of the extremities, three also; Except carbuncle deteriorated blood, four also; Dispelling the wind and dampness pathogens headache, five also.
Radix Angelicae Pubescentis: expelling wind and dampness; Dispersing cold for relieving pain.For anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, headache toothache.< < book on Chinese herbal medicine converges says > >: Radix Angelicae Pubescentis, and benefaction blood system, the medicine of the wet cold expelling of row that dispels the wind is also.The card of all sick wind, can not pitching as head term, and waist knee joint can not bend and stretch, or arthralgia pain is difficult to walk, numbness need not, all wind with cold due to, summer-heat is hindered also with wet institute; Must be by the toil of Radix Angelicae Pubescentis and temperature, activity QI and blood, the cold expelling heresy of dispelling, therefore < < book on Chinese herbal medicine > > says the beriberi of faling apart, change renal mass, treat hernia abdominal mass, subduing inflammation, control harmful wind hundred joints and attack pain, surely lack the strongly fragrant headache of YIN-cold, be intended to this.
Radix Salviae Miltiorrhizae: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.Antithrombotic forms, and improves plasmin activity; Extend, clotting time; Anticoagulant; Improve hemorheological properties.
Spica Prunellae: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, and goiter, swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension, hyperglycemia, hyperlipidemia and high blood viscosity.。< < explaining abstruseness of the canon of materia medica > >: Spica Prunellae, take a tonic or nourishing food to build up one's health the cloudy blood vessels of fainting, can dredge again stagnation of QI.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The Radix Angelicae Dahuricae: wind-damp dispelling, the evacuation of pus of invigorating blood circulation, granulation promoting pain relieving.Antipyretic, analgesia and antiinflammatory action: the Radix Angelicae Dahuricae or Radix angelicae dahuricae decoct 15g (crude drug)/kg gavage, the rabbit generating heat due to the subcutaneous injection peptone of back is had to trivial solution heat effect, its effect is better than the aspirin of 0.1g/kg. Radix Angelicae Dahuricae decoct, ether extract and water extract 8g (crude drug)/kg gavage, suppression ratio to the reaction of mice acetic acid twisting is respectively 69.6%, 52.86% and 40.53%; Hot plate method in mice test also makes pain approve obviously improve, Radix Angelicae Dahuricae decoct 4g (crude drug)/kg gavage, and xylol Suo Gu mice ear inflammation also has obvious inhibitory action. and separately have report, the Radix Angelicae Dahuricae is to folder tail and boiling hot tail induced pain unrestraint effect.
Radix Saposhnikoviae: expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion is jerked surely.There are the effects such as antipyretic, analgesia, calmness and convulsion, antiinflammatory, resisting pathogenic microbes.
Radix Rubiae; Promoting the circulation of blood hemostasis, dredge the meridian passage, eliminating phlegm and stopping cough.< < book on Chinese herbal medicine converges says > >: Radix Rubiae is controlled blood, can manage it and can stop.The gas of invigorating blood circulation, dredges meridians, controls all diseases of blood stagnation arthralgia due to stagnation of blood the most wonderful, and harmless vim and vigour also.
Herba Asari: cold expelling induces sweat; Wind-expelling pain-stopping; Warming the lung to resolve fluid-retention; Sensible.Calm, analgesic activity Herba Asari volatile oil has obvious central inhibitory action, and low dose can make animal peace and quiet, taming, autonomic activities minimizing; Heavy dose can make animal sleep, and has obvious anticonvulsant action.Herba Asari decoct gavages also analgesic activity.Its stronger analgesic activity is the valuable pharmacological basis of its treatment general pain, toothache etc.
Above-mentioned all medicine compatibilities, dispelling wind and removing obstruction in the collateral, blood circulation promoting and dispersing pathogen accumulation, anti-inflammatory analgetic, treatment gout suits pathogenesis, treating both the principal and secondary aspects of a disease.The present invention's formula, medicine source is abundant, and cheap, toxic and side effects is little.
The specific embodiment:
Below in conjunction with embodiment, the invention will be further described:
Embodiment: the Chinese medicine for the treatment of gout, is formed by following ingredients formulated in combination: 12 grams of Ramulus Moris, 9 grams of Caulis Spatholobis, 9 grams, Psychotria rubra (Lour.) Poir. maple, 6 grams of Radix Clematidis, 9 grams of Medulla Tetrapanaciss, 9 grams of Cortex Magnoliae Officinalis, 9 grams of the Radixs Linderae, 9 grams of Rhizoma Chuanxiongs, 9 grams of Radix Paeoniae Rubra, 6 grams of Scorpios, 9 grams of Pheretimas, 6 grams of Rhizoma Et Radix Notopterygiis, 9 grams of Radix Angelicae Pubescentiss, 9 grams of Radix Salviae Miltiorrhizaes, 15 grams of Spica Prunellaes, 6 grams, Radix Glycyrrhizae, 6 grams of the Radixs Angelicae Dahuricae, 9 grams of Radix Saposhnikoviaes, 6 grams of Radix Rubiae, 9 grams of Herba Asaris.Instructions of taking: get above-mentioned Chinese medicine, add water 1500ml, slow fire boiling 45 minutes, drags for slag filtration and make decoction; Every day potion, 14 days courses for the treatment of.
Model case:
Case 1: king so-and-so, man, 42 years old, certain corporate business person.Go on business, treat with courtesy many, often heavy drinking, feels that toes swell and ache while starting at the beginning of 2009, starts to think to be due to fatigue, does not take notice of.Pain increased the weight of afterwards, and after particularly drinking, catch a cold, catching cold, pain is more violent, starts by arthritis treatment, with the medicines such as piroxicam one wheat harvesting period, starts to take a favourable turn, and just loses afterwards effect.Examination in hospital afterwards, blood uric acid, up to 898umol/L, is diagnosed as " gout ".Take Chinese medicine of the present invention 14 days, pain relief, blood uric acid declines, continues to take after 30 days, the above transference cure of patient, blood uric acid has approached normal, within 1 year, pays a return visit, not recurrence.
Case 2: field so-and-so, man, 45 years old, certain business manager.Communicative occasion is many at ordinary times, often heavy drinking, and before half a year, patient feels that toe, ankle repeatability swell and ache, the aggravation of often swelling and ache after drinking, local scorching hot redness, originally thinks due to fatigue.In March, 2010, seizure of disease is to examination in hospital.Have a medical check-up: flushing, red, swollen, the bending pain of left foot toe, function limitation.Red tongue,, yellow and greasy fur, stringy and rolling pulse number.Chemical examination: erythrocyte sedimentation rate: 88mm/h, blood uric acid: 726umol/L.X-ray shows: toe joint has distortion damaged, is diagnosed as gout.Take a course for the treatment of of Chinese medicine decoction of the present invention, pain relief, continued to take after 2 courses for the treatment of, the above transference cure of patient, and blood uric acid has approached normal, continues to strengthen the rehabilitation course for the treatment of.
Case 3: Yan so-and-so, 37 years old, female.Within 2007, suffer from goat, the state of an illness has involved whole body, hurt like hell, and trick joint deforms, inconvenient activity, regular whole body trick joint congestion and swelling pain, overwhelmed with sorrow when serious.Once seen Duo Jia hospital, used multiple Drug therapy, symptom is recurrence again after slightly alleviating, and never has thorough rehabilitation.In August, 2010, starts trial edition invention Chinese medicine preparation, one the course for the treatment of pain relief, continue to take after 2 courses for the treatment of, pain disappears, redness and swelling of joints alleviates, and adheres to treating rehabilitation in three months, pays a return visit without recurrence.
Case 4: Dong so-and-so, man, 49 years old.Inspection in 2006 suffers from goat, has seen Duo Jia hospital, and the state of an illness is controlled.Disease relapse in 2010, once once increased the weight of, and carried out examination in hospital, health check-up uric acid 690mol/ml, ankle arthrosis congestion and swelling pain, moving difficulty.After take a course for the treatment of of Chinese medicine preparation of the present invention, pain relief, blood uric acid declines, and continues to take after 2 courses for the treatment of, pain disappears, blood uric acid has approached normal, takes continuously rehabilitation after three months, can normally work, so far not recurrence.
Case 5: Zhang, man, suffered from goat more than 5 years, and left hand swelling pain unbearably, by western medical treatment, once once controlled always by the state of an illness, but not thoroughly rehabilitation.In February, 2010, the state of an illness was shown effect again, check left hand swelling, blood uric acid 650mol/ml, takes a course for the treatment of of Chinese medicine preparation of the present invention, pain relief, blood uric acid declines, and continues to take after 2 courses for the treatment of, and patient's symptom disappears substantially, blood uric acid has approached normal, take continuously rehabilitation after three months, can normally work, so far not recurrence.
Case 6: king so-and-so, man, 40 years old, certain driver of unit, 2008 suffer from goat, right foot and shank pain, toe joint enlargement, increases the weight of after drinking.Once many hospitalizes, all do not cure, take a course for the treatment of of Chinese medicine decoction of the present invention, pain relief, continue to take after 2 courses for the treatment of, the above transference cure of patient, checks that blood uric acid has approached normal, take continuously rehabilitation after three months, can normally work, so far not recurrence.

Claims (1)

1. the Chinese medicine for the treatment of gout, is characterized in that being formed by following ingredients formulated in combination: 12 grams of Ramulus Moris, 9 grams of Caulis Spatholobis, 9 grams, Psychotria rubra (Lour.) Poir. maple, 6 grams of Radix Clematidis, 9 grams of Medulla Tetrapanaciss, 9 grams of Cortex Magnoliae Officinalis, 9 grams of the Radixs Linderae, 9 grams of Rhizoma Chuanxiongs, 9 grams of Radix Paeoniae Rubra, 6 grams of Scorpios, 9 grams of Pheretimas, 6 grams of Rhizoma Et Radix Notopterygiis, 9 grams of Radix Angelicae Pubescentiss, 9 grams of Radix Salviae Miltiorrhizaes, 15 grams of Spica Prunellaes, 6 grams, Radix Glycyrrhizae, 6 grams of the Radixs Angelicae Dahuricae, 9 grams of Radix Saposhnikoviaes, 6 grams of Radix Rubiae, 9 grams of Herba Asaris; Get above-mentioned Chinese medicine, add water 1500ml, slow fire boiling 45 minutes, drags for slag filtration and makes decoction.
CN201110409099.7A 2011-12-03 2011-12-03 Traditional Chinese medicine for treating gout Expired - Fee Related CN102488768B (en)

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CN103211976B (en) * 2013-05-03 2014-08-20 蔡光正 External-applied traditional medicine preparation for treating gout
CN105079306A (en) * 2014-05-21 2015-11-25 严新兰 Medicinal wine for treating gout
CN105168683A (en) * 2015-08-31 2015-12-23 孟祥来 Medicated wine for treating gout
CN111494546B (en) * 2019-01-31 2021-12-21 西南医科大学附属中医医院 Pharmaceutical composition with effect of relieving gouty pain

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CN1054773C (en) * 1996-06-11 2000-07-26 李文明 Chinese patent drug "Bizhengning" for treatment of arthralgia-syndrome
US6939571B2 (en) * 2002-07-16 2005-09-06 Xiao-Feng Zuo Process of making an osteopathy solution
CN1207024C (en) * 2002-09-08 2005-06-22 许忠文 Chinese medicine composite for treating gouty arthropathy
CN100352465C (en) * 2005-06-02 2007-12-05 高佩贞 Medicinal liquor for treating rheumatic arthrolithiasis and its preparing method
CN100586460C (en) * 2007-08-17 2010-02-03 秦维昌 Oral Chinese medicine composition for treating gout
CN101987150A (en) * 2009-07-31 2011-03-23 天津市公博科技开发有限公司 Chinese medicinal herb preparation for treating gout and preparation method thereof
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