CN102488758B - Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating allergic rhinitis and a preparation method thereof. The traditional Chinese medicine composition comprises the following bulk drugs, by weight: 10-30 parts of cassia twig, 8-25 parts of white peony root, 6-20 parts of radix bupleuri, 10-30 parts of Magnolia liliflora Desr, 10-30 parts of cocklebur, 8-25 parts of Chinese angelica, 5-18 parts of Rorippa indica, 6-20 parts of ligusticum sinense oliver, 3-10 parts of periostracum cicadae, 3-10 parts of windproof, 3-10 parts of polygala root, 3-10 parts of mint and 2-8parts of honey-fried licorice root. The invention also discloses a preparation method of the traditional Chinese medicine composition and clinic curative effect thereof. Clinic curative effect observation test results show that the traditional Chinese medicine composition of the invention has substantial curative effect and fast effectiveness on allergic rhinitis; according to security observation, no clinic adverse reaction is observed, so that the traditional Chinese medicine composition is safe for clinic application and has no toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to Chinese medicine composition of a kind for the treatment of of allergic rhinitis and preparation method thereof, belong to the treatment by Chinese herbs field of allergic rhinitis.
Background technology
Allergic rhinitis (allergic rhinitis) claims allergic rhinitis again, is the allergic disease of nasal membrane, can cause multiple complications.The traditional Chinese medical science is called the nose ware or ware is sneezed." Liu's interchannel medical science six scripts, element ask arcane truth former sick formula " said: " nose person, the nose nose running with watery discharge also ", " sneeze, make in sound also because of the gas blowout of itching in the nose ".Its cardinal symptom of allergic rhinitis clinical findings is that nasal cavity is itched, and sneeze is done frequently, and the thin nasal discharge permanent current is not healed repeatedly.Meet cooler temperature or dust atmosphere etc., Chang Yi brings out primary disease.Allergic rhinitis is common clinical, frequently-occurring disease, can seasonality or perennial onset, and easily outbreak repeatedly is difficult to radical cure.In recent years along with the fast development of process of industrialization, environmental pollution is serious day by day, and anaphylactic disease has the trend that increases day by day, and the allergic rhinitis sickness rate also increases year by year.
Allergic rhinitis causes following complication easily:
1. bronchial asthma: be the allergic rhinitis most common complication, the disease of nasal cavity causes its virus defense disabler, invasion and attack bronchus and even abdominal part.
2. allergic sinusitis: because hole oral mucous membrane edema, the drain that causes having a stuffy nose is obstructed, and the hole intracavity gradually gives birth to negative pressure, and this moment, the patient had headache more, as with infection, can have the allergic sinusitis to produce.
3. secretory otitis media: throat is got involved and then edema is taken place, and makes pharynx stenostomy, obstruction, causes the tympanum negative pressure, and the exudative liquid of middle ear produces.
4. anaphylaxis pharyngolaryngitis: the patient throat also can occur and itch, coughs or have that epiglottis can appear in slight hoarseness, severe patient, the vocal cords myxedema causes dyspnea.
5. nasal polyp: the nasal membrane congestion and edema causes nasal polyp and forms repeatedly, blocks nasal cavity and causes dysfunction of ventilation.
6. olfactory disorder: nasal mucosa edema or nasal cavity infect and injure nervi olfactory.
7. insomnia: long-term nasal obstruction, make that the people is not easy to fall asleep more, cause dyssomnia to cause that spirit is not good, absent minded.
8. feel suffocated and suffocate: the regular big quantity of fluid of nasal cavity stops up, and when the people fell asleep, oral area was habitual closed, can cause that human body feels suffocated, and seriously can cause suffocating.
Because upper respiratory tract and lower respiratory tract have the seriality in the dissection, comprise mucosa continuously, the communicating of tube chamber, the upper respiratory tract infection of allergic rhinitis spreads very easily downwards, present many patient Chang Xianhou or suffer from allergic rhinitis and bronchial asthma simultaneously.Asthma prevalence is than the high 4-20 of normal person times in the Allergic Rhinitis, and asthma prevalence is about 2%-5% in the normal population, and asthma prevalence is about 20%-40% in the Allergic Rhinitis, even 60% allergic rhinitis patient may develop into asthma.
The Therapeutic Method of allergic rhinitis mainly is Drug therapy, comprises that with H2 receptor blocking agent and spraying hormone, the former gets instant result to remove the representative medicine of watery nasal discharge sneeze, but stablizing and alleviating of the state of an illness all do not had too many help; The latter can reduce the hypersusceptibility of nasal membrane to a great extent, but life-time service might cause the fungal infection of nasal cavity regrettably.
Mostly there is slow, the curative effect defective such as remarkable inadequately that takes effect in the existing Chinese patent medicine that is used for the treatment of rhinitis, nasal sinusitis, and haves much room for improvement.
Summary of the invention
Technical problem to be solved by this invention is to overcome the deficiencies in the prior art, and the Chinese medicine composition of a kind of instant effect, evident in efficacy, treatment of allergic rhinitis that safety is good is provided.
Technical problem to be solved by this invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of of allergic rhinitis comprises that each crude drug of following weight portion is made: Ramulus Cinnamomi 10-30 part, Radix Paeoniae Alba 8-25 part, Radix Bupleuri 6-20 part, Flos Magnoliae 10-30 part, Herba Xanthii 10-30 part, Radix Angelicae Sinensis 8-25 part, Semen Lepidii 5-18 part, Rhizoma Ligustici 6-20 part, Periostracum Cicadae 3-10 part, Radix Saposhnikoviae 3-10 part, Radix Polygalae 3-10 part, Herba Menthae 3-10 part, Radix Glycyrrhizae Preparata 2-8 part;
Preferably, the weight portion of each crude drug is: Ramulus Cinnamomi 20-30 part, Radix Paeoniae Alba 10-20 part, Radix Bupleuri 8-15 part, Flos Magnoliae 12-25 part, Herba Xanthii 12-25 part, Radix Angelicae Sinensis 10-20 part, Semen Lepidii 8-14 part, Rhizoma Ligustici 8-18 part, Periostracum Cicadae 5-8 part, Radix Saposhnikoviae 5-8 part, Radix Polygalae 5-8 part, Herba Menthae 5-8 part, Radix Glycyrrhizae Preparata 3-6 part;
Most preferred, the weight portion of each crude drug is: 25 parts of Ramulus Cinnamomi, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 20 parts of Flos Magnoliae, 20 parts of Herba Xanthiis, 15 parts of Radix Angelicae Sinensis, 10 parts of Semen Lepidii, 15 parts of Rhizoma Ligustici, 7 parts of Periostracum Cicadaes, 7 parts of Radix Saposhnikoviaes, 7 parts of Radix Polygalaes, 7 parts of Herba Menthaes, 4 parts of Radix Glycyrrhizae Preparatas.
Chinese medicine composition of the present invention is based on the inventor to the cause of disease of allergic rhinitis, be the rule for the treatment of with awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus, simultaneously according to inventor clinical experience and pharmaceutical research achievement for many years, filter out blood circulation promoting and blood stasis dispelling, the sharp key of nourishing the stomach, promoting flow of QI and blood, sensible, the invigorating spleen to remove dampness of supplementing the brain, QI invigorating body-building, because showing sensible crude drug, according to certain weight proportion prescription, be prepared from.
Ramulus Cinnamomi: be the dry twig of Lauraceae aiphyllium plant Cortex Cinnamomi.Hot, sweet, temperature.GUIXIN, lung, urinary bladder channel.Attending effectiveness: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
The Radix Paeoniae Alba: be the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae (cultigen).Picric acid, cold.Go into liver, spleen channel.Nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Radix Bupleuri: nature and flavor: hardship is slightly cold; Return Liver Channel, gallbladder meridian.Have to evacuate and bring down a fever the effect of yang invigorating soothing liver-QI.Cure mainly: cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, the uterus comes off, menoxenia.
Flos Magnoliae: Magnoliaceae Magnolia liliiflora (Flos Magnoliae) Magnolia liliflora Desr.The property suffering, temperature.Attach to the lung and stomach meridians; Has dispersing wind and cold, the function of clearing the nasal passage.Cure mainly headche due to wind-cold, nasal obstruction, nasal sinusitis, diseases such as turbid nasal discharge.
Herba Xanthii: the fruit of the drying and ripening band involucre of feverfew Herba Xanthii.Property suffering, hardship, temperature, slightly poisonous, return lung meridian.Has wind and heat eliminating, detoxifcation parasite killing, arthralgia chiefly caused by damp pathogen contracture, the wind dehumidifying of loosing, the effect of understand things pain-stopping.Cure mainly flu, wind syndrome of head, dizziness, nasal sinusitis, conjunctival congestion, corneal nebula, pathogenic wind-warm arthralgia pain, contracture numbness etc.
Radix Angelicae Sinensis: warm in nature, sweet in the mouth, suffering.Return liver, the heart, spleen channel.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Semen Lepidii: Cruciferae Semen Lepidii Draba nemorosa L.; Be used as medicine with seed, return lung meridian; The property suffering, hardship, cold; Main function is detumescence expectorant, relieving cough and relieving asthma.
Rhizoma Ligustici: latin name: Ligusticum sinense Oliv; Be distributed in ground such as Henan, Shaanxi, Gansu, Jiangxi, Hunan, Hubei, Sichuan, Yunnan.The property suffering, temperature.Go into urinary bladder channel.Effect: expelling wind and cold, removing dampness to relieve pain.
Periostracum Cicadae (Periostracum Cicadae): exuviae shell when sprouting wings for the larva of cicada Cryptotympana atrata Fabr. Cryptotympana pustulata Fabricius.Summer, Qiu Erji collect, and remove silt, dry.The property sweet, cold.Return lung, Liver Channel.Function cures mainly: the wind heat extraction that looses, sore-throat relieving, rash, nebula removing, spasmolytic.Be used for anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, tetanus.
Radix Saposhnikoviae: the dry root of Saposhnikovia divaricata (Turcz.) Schischk..Nature and flavor suffering, sweet, slightly warm in nature.Return bladder, liver, spleen channel.The effect expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion is jerked surely.Cure mainly the diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus.
Radix Polygalae: property hardship, suffering, tepor.GUIXIN, kidney, lung meridian.Function cures mainly: the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm detumescence.Be used for the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Herba Menthae: the stem and leaf of Labiatae herbaceous plant Herba Menthae.The nature and flavor suffering, cool in nature.The energy dispelling wind and heat pathogens, the clear sharp head, throat is regulated the flow of vital energy.
Radix Glycyrrhizae Preparata: for the honey of Radix Glycyrrhizae is smoked processed goods.The property sweet, flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
In order to reach better therapeutic effect, when patient's pattern of syndrome is the pattern of fever pattern of syndrome, can in above-mentioned Chinese medicine composition, add each crude drug of following weight portion: Radix Scutellariae 5-12 part, Fructus Forsythiae 5-12 part; Preferably, the weight portion of each crude drug is: 10 parts of Radix Scutellariaes, 10 parts of Fructus Forsythiaes.
Radix Scutellariae: Radix Scutellariae another name Radix Scutellariae, tsuchikane tea root.For labiate Radix Scutellariae (Scutellaria baicalensis Georgi), be used as medicine with root.Heat clearing and damp drying is arranged, and removing heat from blood is antiabortive, detoxicating functions.Cure mainly diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.
Fructus Forsythiae: bitter in the mouth, cold nature.Heat-clearing and toxic substances removing, mass dissipating and swelling eliminating.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens;
In order to reach better therapeutic effect, when patient's pattern of syndrome is cold type pattern of syndrome, can in above-mentioned Chinese medicine composition, add following bulk drugs: Radix Aconiti Lateralis Preparata 4-10 part, Rhizoma Zingiberis 3-8 part, Folium Perillae 4-10 part; Preferably, the weight portion of each crude drug is: 8 parts of Radix Aconiti Lateralis Preparatas, 6 parts of Rhizoma Zingiberiss, 8 parts of Folium Perillaes.
Radix Aconiti Lateralis Preparata: be the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx. aconitum carmichaeli debx..Meridian distribution of property and flavor: hot, sweet, big heat; Poisonous.GUIXIN, kidney, spleen channel.Function: recuperating depleted YANG and rescuing the patient from collapse, it is supporing yang to mend fire, dispersing cold for relieving pain.Cure mainly: be used for excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea is fainted contrary, the cold extremities faint pulse, trusted subordinate's cold type of pain, cold-dysentery, the beriberi edema, anemofrigid-damp arthralgia, sexual impotence, cold womb, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, the disease of carbuncle of yin nature skin infection and all chronic diseaseses.
Rhizoma Zingiberis: be zingiberaceous plant Rhizoma Alpiniae Officinarum rhizome.Suffering, heat.Return spleen, stomach warp; Dispersing cold for relieving pain, warming middle-JIAO to arrest vomiting.
Folium Perillae: for Labiatae Perilla plant Folium Perillae [Perilla frutescens (L.) Brltt.var.arguta Benth.Hand.-Mazz. " band leaf twig.The property suffering, temperature.Return lung, spleen channel.Function cures mainly: relieving the exterior syndrome by diaphoresis, regulating the flow of QI to ease the stomach, solving toxin of fish and crab.Be used for anemofrigid cold, headache, cough, distension and fullness of the chest and abdomen, the fish Eriocheir sinensis poisons.
In order to reach better therapeutic effect, when the patient has the headache symptom, can in above-mentioned Chinese medicine composition, add following bulk drugs: Rhizoma Chuanxiong 5-12 part, Herba Asari 5-12 part, Rhizoma Et Radix Notopterygii 4-10 part; Preferably, the weight portion of each crude drug is: 8 parts of Rhizoma Chuanxiongs, 8 parts of Herba Asaris, 6 parts of Rhizoma Et Radix Notopterygiis.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for pacifying nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Herba Asari: effect: cold expelling induces sweat; Wind-expelling pain-stopping; Warming the lung to resolve fluid-retention; Sensible.Gui Jing: lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel.Cure mainly: exterior syndrome due to wind-cold; Headache, toothache; Rheumatic arthralgia; The phlegm retention cough with asthma; Nasal obstruction; Nasal sinusitis; Aphtha.
Rhizoma Et Radix Notopterygii: acrid in the mouth; Bitter; Warm in nature.Effect: the exterior cold of loosing; Wind-damp dispelling; Sharp joint; Pain relieving.Cure mainly: affection of exogenous wind-cold; It is lossless to have a headache; Mimeograph cold-damp numbness; The edema due to wind pathogen edema; Sore swollen toxin.
When patient's pattern of syndrome is deficiency of vital energy pattern of syndrome, in order to reach better therapeutic effect, can in above-mentioned Chinese medicine composition, add following bulk drugs: Radix Astragali 5-12 part and Fructus Jujubae 5-12 part; Preferably, the weight portion of each crude drug is: 8 parts of the Radixs Astragali, 8 parts in Fructus Jujubae.
The Radix Astragali: the Radix Astragali is the root of leguminous herbaceous plant's Radix Astagali, Radix Astragali, nature and flavor: sweet, and tepor.Have effects such as invigorating QI to consolidate the body surface resistance, diuretic detumescent, expelling pus and toxin by strengthening QI, granulation promoting.
Fructus Jujubae: sweet, temperature.Return spleen, stomach warp; The spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid transfers battalion to defend, and separates poison of drug.Control the insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid deficiency, disharmony of nutrient QI with defensive QI, severe palpitation.
The specification of the crude drug of respectively distinguishing the flavor of that the present invention is used all meets national medical standard, can buy at pharmacy to obtain.
Chinese medicine composition of the present invention can be prepared into any acceptable oral preparation clinically by this area conventional formulation method; Described oral formulations includes but not limited to tablet, capsule, granule, powder, pill, oral liquid, syrup or drop pill etc.
A kind of preparation method of Chinese medicine composition of the present invention: after each crude drug of the present invention taken by weighing by described weight portion proportioning, pulverize, sieve (for example can be the 400-1000 mesh sieve), namely.Certainly, after also each crude drug can being pulverized, add required adjuvant or the excipient of preparations shaping, be prepared into capsule, tablet or pill according to conventional method.
Preferably, a kind of method for preparing above-mentioned Chinese medicine composition may further comprise the steps:
(1) takes by weighing each crude drug by described weight proportion;
(2) get each crude drug and decoct with water, decoction liquor filters, and merging filtrate is condensed into thick paste, and drying gets dry extract, and is standby;
(3) with dry extract and the pharmaceutical preparation auxiliary materials and mixing of step (2) gained, make the preparation semi-finished product, make the preparation finished product through preparations shaping technology again.
Preferably, in the step (2) each crude drug is decocted with water 2 times, the decocting that wherein adds 3-8 times of weight for the 1st time boiled 1-2.5 hour, and the decocting that adds 3-5 times of weight for the 2nd time boiled 1-2.5 hour;
Preferably, in the step (2) filtrate being condensed into 55 ℃ of relative densities when measuring is 1.06～1.10 thick paste;
Drying described in the step (2) can be spray drying, lyophilization or vacuum drying, is preferably spray drying.
Clinical efficacy evidence, Chinese medicine composition of the present invention have sensible, the invigorating spleen to remove dampness of supplementing the brain, and be fast for responding well to treatment of allergic rhinitis because showing effects such as sensible, determined curative effect, and clinical application do not see any toxic and side effects, safety is good.
The usage of Chinese medicine composition of the present invention and consumption: dosage of the present invention depends on factors such as concrete dosage form, patient's age, health status.As guidance: for capsule, oral: calculate with contained crude drug amount in the Chinese medicine composition, 3 times on the one, each 2.7g-5.4g.
The specific embodiment
Further describe the present invention below in conjunction with specific embodiment, advantage of the present invention and characteristics will be more clear along with description.But these embodiment only are exemplary, scope of the present invention are not constituted any restriction.It will be understood by those skilled in the art that and down can make amendment or replace the details of technical solution of the present invention and form without departing from the spirit and scope of the present invention, but these modifications and replacing all fall within the scope of protection of the present invention.
The preparation of embodiment 1 capsule
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 25, the Radix Paeoniae Alba 15, Radix Bupleuri 10, Flos Magnoliae 20, Herba Xanthii 20, Radix Angelicae Sinensis 15, Semen Lepidii 10, Rhizoma Ligustici 15, Periostracum Cicadae 7, Radix Saposhnikoviae 7, Radix Polygalae 7, Herba Menthae 7, Radix Glycyrrhizae Preparata 4;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 2 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 10, the Radix Paeoniae Alba 8, Radix Bupleuri 6, Flos Magnoliae 10, Herba Xanthii 10, Radix Angelicae Sinensis 8, Semen Lepidii 5, Rhizoma Ligustici 6, Periostracum Cicadae 3, Radix Saposhnikoviae 3, Radix Polygalae 3, Herba Menthae 3, Radix Glycyrrhizae Preparata 2;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 3 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 30, the Radix Paeoniae Alba 25, Radix Bupleuri 20, Flos Magnoliae 30, Herba Xanthii 30, Radix Angelicae Sinensis 25, Semen Lepidii 18, Rhizoma Ligustici 20, Periostracum Cicadae 10, Radix Saposhnikoviae 10, Radix Polygalae 10, Herba Menthae 10, Radix Glycyrrhizae Preparata 8;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 4 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 20, the Radix Paeoniae Alba 10, Radix Bupleuri 8, Flos Magnoliae 12, Herba Xanthii 12, Radix Angelicae Sinensis 10, Semen Lepidii 8, Rhizoma Ligustici 8, Periostracum Cicadae 5, Radix Saposhnikoviae 5, Radix Polygalae 5-8, Herba Menthae 5, Radix Glycyrrhizae Preparata 3;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 5 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 30, the Radix Paeoniae Alba 20, Radix Bupleuri 15, Flos Magnoliae 25, Herba Xanthii 25, Radix Angelicae Sinensis 20, Semen Lepidii 14, Rhizoma Ligustici 18, Periostracum Cicadae 8, Radix Saposhnikoviae 8, Radix Polygalae 8, Herba Menthae 8, Radix Glycyrrhizae Preparata 6;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 6 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 25, the Radix Paeoniae Alba 15, Radix Bupleuri 10, Flos Magnoliae 20, Herba Xanthii 20, Radix Angelicae Sinensis 15, Semen Lepidii 10, Rhizoma Ligustici 15, Periostracum Cicadae 7, Radix Saposhnikoviae 7, Radix Polygalae 7, Herba Menthae 7, Radix Glycyrrhizae Preparata 4, Radix Scutellariae 10, Fructus Forsythiae 10;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 7 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 10, the Radix Paeoniae Alba 8, Radix Bupleuri 6, Flos Magnoliae 10, Herba Xanthii 10, Radix Angelicae Sinensis 8, Semen Lepidii 5, Rhizoma Ligustici 6, Periostracum Cicadae 3, Radix Saposhnikoviae 3, Radix Polygalae 3, Herba Menthae 3, Radix Glycyrrhizae Preparata 2, Radix Scutellariae 5, Fructus Forsythiae 5;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 8 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 30, the Radix Paeoniae Alba 25, Radix Bupleuri 20, Flos Magnoliae 30, Herba Xanthii 30, Radix Angelicae Sinensis 25, Semen Lepidii 18, Rhizoma Ligustici 20, Periostracum Cicadae 10, Radix Saposhnikoviae 10, Radix Polygalae 10, Herba Menthae 10, Radix Glycyrrhizae Preparata 8, Radix Scutellariae 12, Fructus Forsythiae 12;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 9 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 25, the Radix Paeoniae Alba 15, Radix Bupleuri 10, Flos Magnoliae 20, Herba Xanthii 20, Radix Angelicae Sinensis 15, Semen Lepidii 10, Rhizoma Ligustici 15, Periostracum Cicadae 7, Radix Saposhnikoviae 7, Radix Polygalae 7, Herba Menthae 7, Radix Glycyrrhizae Preparata 4, Radix Aconiti Lateralis Preparata 8, Rhizoma Zingiberis 6, Folium Perillae 8;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 10 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 10, the Radix Paeoniae Alba 8, Radix Bupleuri 6, Flos Magnoliae 10, Herba Xanthii 10, Radix Angelicae Sinensis 8, Semen Lepidii 5, Rhizoma Ligustici 6, Periostracum Cicadae 3, Radix Saposhnikoviae 3, Radix Polygalae 3, Herba Menthae 3, Radix Glycyrrhizae Preparata 2, Radix Aconiti Lateralis Preparata 4, Rhizoma Zingiberis 3, Folium Perillae 4;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 11 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 30, the Radix Paeoniae Alba 25, Radix Bupleuri 20, Flos Magnoliae 30, Herba Xanthii 30, Radix Angelicae Sinensis 25, Semen Lepidii 18, Rhizoma Ligustici 20, Periostracum Cicadae 10, Radix Saposhnikoviae 10, Radix Polygalae 10, Herba Menthae 10, Radix Glycyrrhizae Preparata 8, Radix Aconiti Lateralis Preparata 10, Rhizoma Zingiberis 8, Folium Perillae 10;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 12 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 25, the Radix Paeoniae Alba 15, Radix Bupleuri 10, Flos Magnoliae 20, Herba Xanthii 20, Radix Angelicae Sinensis 15, Semen Lepidii 10, Rhizoma Ligustici 15, Periostracum Cicadae 7, Radix Saposhnikoviae 7, Radix Polygalae 7, Herba Menthae 7, Radix Glycyrrhizae Preparata 4, Rhizoma Chuanxiong 8, Herba Asari 8, Rhizoma Et Radix Notopterygii 6;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 13 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 10, the Radix Paeoniae Alba 8, Radix Bupleuri 6, Flos Magnoliae 10, Herba Xanthii 10, Radix Angelicae Sinensis 8, Semen Lepidii 5, Rhizoma Ligustici 6, Periostracum Cicadae 3, Radix Saposhnikoviae 3, Radix Polygalae 3, Herba Menthae 3, Radix Glycyrrhizae Preparata 2, Rhizoma Chuanxiong 5, Herba Asari 5, Rhizoma Et Radix Notopterygii 4;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 14 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 30, the Radix Paeoniae Alba 25, Radix Bupleuri 20, Flos Magnoliae 30, Herba Xanthii 30, Radix Angelicae Sinensis 25, Semen Lepidii 18, Rhizoma Ligustici 20, Periostracum Cicadae 10, Radix Saposhnikoviae 10, Radix Polygalae 10, Herba Menthae 10, Radix Glycyrrhizae Preparata 8, Rhizoma Chuanxiong 12, Herba Asari 12, Rhizoma Et Radix Notopterygii 10;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 15 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 25, the Radix Paeoniae Alba 15, Radix Bupleuri 10, Flos Magnoliae 20, Herba Xanthii 20, Radix Angelicae Sinensis 15, Semen Lepidii 10, Rhizoma Ligustici 15, Periostracum Cicadae 7, Radix Saposhnikoviae 7, Radix Polygalae 7, Herba Menthae 7, Radix Glycyrrhizae Preparata 4, the Radix Astragali 8, Fructus Jujubae 8;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 16 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 10, the Radix Paeoniae Alba 8, Radix Bupleuri 6, Flos Magnoliae 10, Herba Xanthii 10, Radix Angelicae Sinensis 8, Semen Lepidii 5, Rhizoma Ligustici 6, Periostracum Cicadae 3, Radix Saposhnikoviae 3, Radix Polygalae 3, Herba Menthae 3, Radix Glycyrrhizae Preparata 2, the Radix Astragali 5, Fructus Jujubae 5;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The preparation of embodiment 17 capsules
(1) takes by weighing clean medical material (unit: g): Ramulus Cinnamomi 30, the Radix Paeoniae Alba 25, Radix Bupleuri 20, Flos Magnoliae 30, Herba Xanthii 30, Radix Angelicae Sinensis 25, Semen Lepidii 18, Rhizoma Ligustici 20, Periostracum Cicadae 10, Radix Saposhnikoviae 10, Radix Polygalae 10, Herba Menthae 10, Radix Glycyrrhizae Preparata 8, the Radix Astragali 12, Fructus Jujubae 12;
(2) preparation of dry extract
Decoct with water twice after above-mentioned each crude drug mixed, the decocting that adds for the first time 10 times of weight boiled 2.5 hours, the decocting that adds for the second time 8 times of weight boiled 1.5 hours, decoction liquor filters, merging filtrate, filtrate are concentrated into the thick paste that relative density is 1.06～1.10 (55 ℃), spray drying, get dry extract, standby;
(3) preparation of capsule
Get it filled material fine powder and dry extract add an amount of lactose, mixing, and dry-pressing becomes granule, incapsulates, namely; Containing effective crude drug amount in every capsules is 1.33g.
The hypersensitive clinical observation on the therapeutic effect test of test example 1 traditional Chinese medicine composition for treating of the present invention
One, clinical physical data
Accept 225 routine Allergic Rhinitis altogether for medical treatment; Patient age 6-69 year, 38 years old mean age.With between twenty and fifty number in the majority between 18～40 years old; The course of disease the shortest half a year reaches 12 years most, and the overwhelming majority is 2～4 years outbreak, cureless patients repeatedly; All the clinical manifestation of cases all has nasal cavity in various degree to itch, and sneeze is done frequently, thin nasal discharge permanent current, and symptom such as the slight dizzy headache of companion.
Two, trial drug
The capsule that embodiment of the invention 1-17 is prepared.
Three, Therapeutic Method
225 routine patients are divided into 5 groups at random, that is: test 1 group, 2 groups of tests, 3 groups of tests, test 4 groups and test 5 groups, every group of each 45 example; Test 1 group and adopt the prepared capsule treatment of embodiment 1-5, test 2 groups and adopt the prepared capsule treatment of embodiment 6-8; Test 3 groups and adopt the prepared capsule treatment of embodiment 9-11, test 4 groups and adopt the prepared capsule treatment of embodiment 12-14; Test 5 groups and adopt the prepared capsule treatment of embodiment 15-17; Oral, one time 8 (0.6g crude drug/grain), 3 times on the one, 15 days is a course for the treatment of, treats 3 courses for the treatment of altogether; Period in a medicine is withdrawn other related drugs and other treatment.
Four, efficacy assessment standard
Efficacy assessment standard and foundation: 1. produce effects: BITONG gas is good, transference cures such as nasal cavity is itched, sneeze is done frequently, thin nasal discharge permanent current; 2. effective: nasal cavity is itched, and sneeze is done frequently, and symptoms such as thin nasal discharge permanent current take a turn for the better, and the pus tears disappear, and headache alleviates; 3. invalid: treat 3 more than the course for the treatment of, symptom does not have the improver.
Five, therapeutic outcome
Clinical observation on the therapeutic effect the results are shown in Table 1.
The clinical observation on the therapeutic effect result of the test of table 1 traditional Chinese medicine composition for treating allergic rhinitis of the present invention
Clinical observation on the therapeutic effect is the result show, Chinese medicine composition of the present invention has significant curative effect and instant effect for allergic rhinitis; Safety observe to be found, does not observe any clinical adverse, show Chinese medicine composition clinical practice of the present invention safely, have no side effect.
Claims (12)
1. the Chinese medicine composition of a treatment of allergic rhinitis, it is characterized in that, made by each crude drug of following weight portion: Ramulus Cinnamomi 10-30 part, Radix Paeoniae Alba 8-25 part, Radix Bupleuri 6-20 part, Flos Magnoliae 10-30 part, Herba Xanthii 10-30 part, Radix Angelicae Sinensis 8-25 part, Semen Lepidii 5-18 part, Rhizoma Ligustici 6-20 part, Periostracum Cicadae 3-10 part, Radix Saposhnikoviae 3-10 part, Radix Polygalae 3-10 part, Herba Menthae 3-10 part, Radix Glycyrrhizae Preparata 2-8 part, Radix Scutellariae 5-12 part and Fructus Forsythiae 5-12 part.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that the weight portion of each crude drug is: 25 parts of Ramulus Cinnamomi, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 20 parts of Flos Magnoliae, 20 parts of Herba Xanthiis, 15 parts of Radix Angelicae Sinensis, 10 parts of Semen Lepidii, 15 parts of Rhizoma Ligustici, 7 parts of Periostracum Cicadaes, 7 parts of Radix Saposhnikoviaes, 7 parts of Radix Polygalaes, 7 parts of Herba Menthaes, 4 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Scutellariaes, 10 parts of Fructus Forsythiaes.
3. the Chinese medicine composition of a treatment of allergic rhinitis, it is characterized in that, made by each crude drug of following weight portion: Ramulus Cinnamomi 10-30 part, Radix Paeoniae Alba 8-25 part, Radix Bupleuri 6-20 part, Flos Magnoliae 10-30 part, Herba Xanthii 10-30 part, Radix Angelicae Sinensis 8-25 part, Semen Lepidii 5-18 part, Rhizoma Ligustici 6-20 part, Periostracum Cicadae 3-10 part, Radix Saposhnikoviae 3-10 part, Radix Polygalae 3-10 part, Herba Menthae 3-10 part, Radix Glycyrrhizae Preparata 2-8 part, Radix Aconiti Lateralis Preparata 4-10 part, Rhizoma Zingiberis 3-8 part and Folium Perillae 4-10 part.
4. according to the described Chinese medicine composition of claim 3, it is characterized in that the weight portion of each crude drug is: 25 parts of Ramulus Cinnamomi, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 20 parts of Flos Magnoliae, 20 parts of Herba Xanthiis, 15 parts of Radix Angelicae Sinensis, 10 parts of Semen Lepidii, 15 parts of Rhizoma Ligustici, 7 parts of Periostracum Cicadaes, 7 parts of Radix Saposhnikoviaes, 7 parts of Radix Polygalaes, 7 parts of Herba Menthaes, 4 parts of Radix Glycyrrhizae Preparatas, 8 parts of Radix Aconiti Lateralis Preparatas, 6 parts of Rhizoma Zingiberiss, 8 parts of Folium Perillaes.
5. the Chinese medicine composition of a treatment of allergic rhinitis, it is characterized in that, made by each crude drug of following weight portion: Ramulus Cinnamomi 10-30 part, Radix Paeoniae Alba 8-25 part, Radix Bupleuri 6-20 part, Flos Magnoliae 10-30 part, Herba Xanthii 10-30 part, Radix Angelicae Sinensis 8-25 part, Semen Lepidii 5-18 part, Rhizoma Ligustici 6-20 part, Periostracum Cicadae 3-10 part, Radix Saposhnikoviae 3-10 part, Radix Polygalae 3-10 part, Herba Menthae 3-10 part, Radix Glycyrrhizae Preparata 2-8 part, Rhizoma Chuanxiong 5-12 part, Herba Asari 5-12 part and Rhizoma Et Radix Notopterygii 4-10 part.
6. according to the described Chinese medicine composition of claim 5, it is characterized in that the weight portion of each crude drug is: 25 parts of Ramulus Cinnamomi, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 20 parts of Flos Magnoliae, 20 parts of Herba Xanthiis, 15 parts of Radix Angelicae Sinensis, 10 parts of Semen Lepidii, 15 parts of Rhizoma Ligustici, 7 parts of Periostracum Cicadaes, 7 parts of Radix Saposhnikoviaes, 7 parts of Radix Polygalaes, 7 parts of Herba Menthaes, 4 parts of Radix Glycyrrhizae Preparatas, 8 parts of Rhizoma Chuanxiongs, 8 parts of Herba Asaris, 6 parts of Rhizoma Et Radix Notopterygiis.
7. the Chinese medicine composition of a treatment of allergic rhinitis, it is characterized in that, made by each crude drug of following weight portion: Ramulus Cinnamomi 10-30 part, Radix Paeoniae Alba 8-25 part, Radix Bupleuri 6-20 part, Flos Magnoliae 10-30 part, Herba Xanthii 10-30 part, Radix Angelicae Sinensis 8-25 part, Semen Lepidii 5-18 part, Rhizoma Ligustici 6-20 part, Periostracum Cicadae 3-10 part, Radix Saposhnikoviae 3-10 part, Radix Polygalae 3-10 part, Herba Menthae 3-10 part, Radix Glycyrrhizae Preparata 2-8 part, Radix Astragali 5-12 part and Fructus Jujubae 5-12 part.
8. according to the described Chinese medicine composition of claim 7, it is characterized in that the weight portion of each crude drug is: 25 parts of Ramulus Cinnamomi, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 20 parts of Flos Magnoliae, 20 parts of Herba Xanthiis, 15 parts of Radix Angelicae Sinensis, 10 parts of Semen Lepidii, 15 parts of Rhizoma Ligustici, 7 parts of Periostracum Cicadaes, 7 parts of Radix Saposhnikoviaes, 7 parts of Radix Polygalaes, 7 parts of Herba Menthaes, 4 parts of Radix Glycyrrhizae Preparatas, 8 parts of the Radixs Astragali, 8 parts in Fructus Jujubae.
9. according to any one described Chinese medicine composition of claim 1-8, it is characterized in that: it is prepared into any acceptable oral drug preparation clinically.
10. according to the described Chinese medicine composition of claim 9, it is characterized in that: described oral drug preparation is pill, powder, granule, capsule, tablet or oral liquid.
11. a method for preparing any one described Chinese medicine composition of claim 1-8 may further comprise the steps:
(1), takes by weighing each crude drug by described weight proportion;
(2), each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, preparations shaping, namely.
12. the purposes of any one described Chinese medicine composition of claim 1-8 in preparation treatment of allergic rhinitis medicine.
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| CN105168694A (en) * | 2015-09-30 | 2015-12-23 | 吴淑芬 | Traditional Chinese medicine composition for treating nasal polyps |
| CN107582655A (en) * | 2017-08-29 | 2018-01-16 | 成都泠汐尚品科技有限公司 | A kind of preparation method for being used to treat the Chinese medicine composition of allergic rhinitis |
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| Title |
|---|
| 李云鹏.过敏性鼻炎中医治疗概况.《甘肃中医学院学报》.2007,第24卷(第4期),第49-52页. |
| 过敏性鼻炎中医治疗概况;李云鹏;《甘肃中医学院学报》;20070831;第24卷(第4期);第49-52页 * |
| 郭静,等.中医治疗过敏性鼻炎研究概况.《实用中西医结合临床》.2004,第4卷(第6期),第84-85页. * |
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