CN102488756B - 一种治疗干眼症的药剂 - Google Patents
一种治疗干眼症的药剂 Download PDFInfo
- Publication number
- CN102488756B CN102488756B CN 201110407147 CN201110407147A CN102488756B CN 102488756 B CN102488756 B CN 102488756B CN 201110407147 CN201110407147 CN 201110407147 CN 201110407147 A CN201110407147 A CN 201110407147A CN 102488756 B CN102488756 B CN 102488756B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- medicament
- herba
- dry eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 17
- 206010013774 Dry eye Diseases 0.000 title abstract description 6
- 208000003556 Dry Eye Syndromes Diseases 0.000 title abstract description 5
- 241001646826 Isodon rubescens Species 0.000 claims abstract description 6
- 208000005494 xerophthalmia Diseases 0.000 claims description 11
- 241000756943 Codonopsis Species 0.000 claims description 5
- 210000000582 semen Anatomy 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 241000522254 Cassia Species 0.000 claims description 2
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims description 2
- 229940079593 drug Drugs 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 2
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 235000014722 Aralia cordata Nutrition 0.000 abstract 1
- 244000294554 Aralia racemosa Species 0.000 abstract 1
- 235000004446 Aralia racemosa Nutrition 0.000 abstract 1
- 241000758794 Asarum Species 0.000 abstract 1
- 244000201986 Cassia tora Species 0.000 abstract 1
- 235000014552 Cassia tora Nutrition 0.000 abstract 1
- 241000007126 Codonopsis pilosula Species 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 235000010658 Lavandula latifolia Nutrition 0.000 abstract 1
- 235000003805 Musa ABB Group Nutrition 0.000 abstract 1
- 240000008790 Musa x paradisiaca Species 0.000 abstract 1
- 235000015266 Plantago major Nutrition 0.000 abstract 1
- 244000153955 Reynoutria sachalinensis Species 0.000 abstract 1
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 abstract 1
- 244000272264 Saussurea lappa Species 0.000 abstract 1
- 235000006784 Saussurea lappa Nutrition 0.000 abstract 1
- 240000003705 Senecio vulgaris Species 0.000 abstract 1
- 241000205578 Thalictrum Species 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000004043 dyeing Methods 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 208000007775 Congenital alacrima Diseases 0.000 description 1
- 206010015958 Eye pain Diseases 0.000 description 1
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 description 1
- 208000012902 Nervous system disease Diseases 0.000 description 1
- 206010034960 Photophobia Diseases 0.000 description 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 description 1
- 206010048222 Xerosis Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000001387 anti-histamine Effects 0.000 description 1
- 239000000739 antihistaminic agent Substances 0.000 description 1
- 239000000812 cholinergic antagonist Substances 0.000 description 1
- 208000036549 congenital autosomal dominant alacrima Diseases 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000007919 dispersible tablet Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003560 epithelium corneal Anatomy 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
本发明涉及一种治疗干眼症的药剂，它是由下述重量配比的物质制成：车前草5-10份、甘松1-5份、马尾连3-10份、千里光5-10份、冬凌草1-5份、木香1-5份、虎杖5-15份、党参1-3份、决明子3-5份、当归1-5份和细辛1-5份。本发明所述的治疗干眼症的药剂都采用天然药物制成，疗效明确，可有效地治疗干眼症，因此十分适宜在临床上推广。
Description
技术领域
本发明涉及医药领域，具体来说涉及一种治疗干眼症的药剂。
背景技术
干燥症是由于眼泪的数量不足或者质量差，导致的眼部干燥的综合症。严重的干眼可以导致角膜上皮的损伤。眼泪的数量不足：正常人，每只眼分泌泪液的速度是：1μL/分钟。分泌不足或者蒸发量过大都会造成眼泪数量的不足。眼泪的质量差：正常的泪液在眼表形成一层泪膜，泪膜从外到内分为三层：脂质层、水层、粘蛋白层，任何一层出现异常泪液的质量都会降低。目前，需要不断研发新的治疗干眼症的方法。
发明内容
本发明的目的是提供一种治疗干眼症的药剂。
为了实现本发明的目的，本发明提供一种治疗干眼症的药剂，它是由下述重量配比的物质制成：车前草5-10份、甘松1-5份、马尾连3-10份、千里光5-10份、冬凌草1-5份、木香1-5份、虎杖5-15份、党参1-3份、决明子3-5份、当归1-5份和细辛1-5份。
优选地，本发明所述的治疗干眼症的药剂是由下述重量配比的物质制成：车前草5份、甘松3份、马尾连5份、千里光8份、冬凌草3份、木香3份、虎杖10份、党参2份、决明子5份、当归3份和细辛5份。
更优选地，本发明所述的药剂为片剂、分散片、汤剂、或搽剂。
本发明所述的治疗干眼症的药剂都采用天然药物制成，疗效明确，可有效地治疗干眼症，因此十分适宜在临床上推广。
具体实施方式
下面通过实施例进一步说明本发明。应该理解的是，本发明的实施例是用于说明本发明而不是对本发明的限制。根据本发明的实质对本发明进行的简单改进都属于本发明要求保护的范围。除非另有说明，否则本发明中的百分数是重量百分数。
实施例1汤剂的制备
取车前草50克、甘松30克、马尾连50克、千里光80克、冬凌草30克、木香30克、虎杖100克、党参20克、决明子50克、当归30克和细辛50克，加入2000毫升水，在80℃下加热2小时，过滤。将滤液浓缩至500毫升，冷却中室温，即得本发明的汤剂。
实验例
选择干眼症患者50例，其中男性25例，年龄36-68岁，女性25例，年龄38-70岁。纳入标准：有眼干涩感、异物感、疲劳、眼红、畏光、烧灼感、眼酸胀、眼痛，泪液功能检查：SCHER MER I＜10mm，BUT＜10s。排除先天性无泪症、无泪腺、神经障碍等，用药期间禁用全身性抗组胺、抗胆碱药物。
使用实施例1制备的汤剂进行治疗，一日两次，每次服用20毫升，连续治疗一个星期为一个疗程。
疗效评定标准
治愈：症状消失，角膜染色减少，Schirmer试验多次测定＞10mm/5min；好转：症状减轻，角膜染色减少，Schirmer试验多次测定泪液分泌量有所增加；无效：症状无改善，角膜染色无变化或增多，Schirmer试验多次测定泪液的分泌未增加。
结果
在共50例患者中，全部符合治愈标准。
不良反应
对于50例患者在治疗过程中进行跟踪观察，未发现明显的不良反应。
Claims (2)
1.一种治疗干眼症的药剂，其特征在于，它是由下述重量配比的物质制成：车前草5-10份、甘松1-5份、马尾连3-10份、千里光5-10份、冬凌草1-5份、木香1-5份、虎杖5-15份、党参1-3份、决明子3-5份、当归1-5份和细辛1-5份。
2.根据权利要求1所述的治疗干眼症的药剂，其特征在于，它是由下述重量配比的物质制成：车前草5份、甘松3份、马尾连5份、千里光8份、冬凌草3份、木香3份、虎杖10份、党参2份、决明子5份、当归3份和细辛5份。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110407147 CN102488756B (zh) | 2011-12-09 | 2011-12-09 | 一种治疗干眼症的药剂 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110407147 CN102488756B (zh) | 2011-12-09 | 2011-12-09 | 一种治疗干眼症的药剂 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102488756A CN102488756A (zh) | 2012-06-13 |
| CN102488756B true CN102488756B (zh) | 2013-04-17 |
Family
ID=46180657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110407147 Expired - Fee Related CN102488756B (zh) | 2011-12-09 | 2011-12-09 | 一种治疗干眼症的药剂 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102488756B (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961466A (zh) * | 2014-04-24 | 2014-08-06 | 青岛市市立医院 | 一种治疗干眼症的口服方剂 |
| CN105125924A (zh) * | 2015-09-22 | 2015-12-09 | 淄博齐鼎立专利信息咨询有限公司 | 一种用于治疗干眼症的药物制剂 |
| KR20180136039A (ko) * | 2017-06-13 | 2018-12-24 | 한국 한의학 연구원 | 호장근 추출물 또는 이의 분획물을 포함하는 안구건조증 예방 및 치료용 조성물 |
| KR102317829B1 (ko) * | 2018-11-28 | 2021-11-24 | 삼일제약주식회사 | 안정성이 증진된 경구투여용 호장근 추출물을 포함하는 고형제제 및 이의 제조방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1146907A (zh) * | 1995-10-05 | 1997-04-09 | 隋振明 | 治疗眼疾用药物的配方及工艺 |
| CN101185700B (zh) * | 2007-12-19 | 2010-09-29 | 王崇才 | 一种治疗白内障的药物 |
| CN101306125A (zh) * | 2008-06-10 | 2008-11-19 | 王芳 | 一种治疗急性结膜炎的汤剂药物 |
| CN101647947A (zh) * | 2008-09-24 | 2010-02-17 | 内蒙古库伦蒙药厂 | 一种治疗眼病的蒙药制剂 |
| CN101773653B (zh) * | 2010-04-20 | 2011-04-27 | 泰一和浦（北京）中医药研究院有限公司 | 一种治疗目盲的中药组合物及其制备方法 |
| CN101940769A (zh) * | 2010-06-09 | 2011-01-12 | 郭向荣 | 近视远视丸 |
| CN101869640A (zh) * | 2010-07-02 | 2010-10-27 | 李岩 | 一种治疗近视的中药 |
| CN101972427A (zh) * | 2010-10-19 | 2011-02-16 | 毛成艺 | 一种治疗慢性青光眼的中药 |
-
2011
- 2011-12-09 CN CN 201110407147 patent/CN102488756B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN102488756A (zh) | 2012-06-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103142968B (zh) | 一种治疗干眼症的药剂 | |
| CN102488756B (zh) | 一种治疗干眼症的药剂 | |
| CN102698079A (zh) | 一种治疗干眼症的药物组合物及其制备方法和用途 | |
| CN102302686B (zh) | 一种治疗干眼症的药剂 | |
| CN104043045A (zh) | 治疗视神经萎缩的药物组合物 | |
| CN103142959A (zh) | 一种治疗荨麻疹的药剂 | |
| CN101332268B (zh) | 一种治疗鼻炎、鼻窦炎的药物 | |
| CN102940867A (zh) | 一种治疗干眼症的中药组合物 | |
| CN102526307A (zh) | 用于治疗带状疱疹的中药组合物 | |
| CN101411770B (zh) | 一种治疗瘀血阻滞型多发性硬化症的药物 | |
| CN104940516B (zh) | 一种治疗慢性再生障碍性贫血的中药组合物及其制备方法与应用 | |
| CN103055055A (zh) | 一种治疗皮肤病的中药 | |
| CN102949555B (zh) | 一种治疗糖尿病足的药物 | |
| CN102379925A (zh) | 一种治疗糖尿病性皮肤瘙痒的中药 | |
| CN101953892A (zh) | 一种治疗糖尿病性皮肤瘙痒的中药 | |
| CN103191397B (zh) | 一种治疗医院信息人员的干眼症的药剂 | |
| CN102380017A (zh) | 一种治疗糖尿病的药物及其制备方法 | |
| CN101961387A (zh) | 一种治疗糖尿病性皮肤瘙痒的中药 | |
| CN101313955B (zh) | 抗皮肤真菌复方制剂 | |
| CN102397336A (zh) | 一种治疗糖尿病性皮肤瘙痒的中药 | |
| CN102389460A (zh) | 一种治疗糖尿病性皮肤瘙痒的中药 | |
| CN105168503A (zh) | 一种用于防治放射性皮炎的外用中药组合物及其制备方法 | |
| CN103202992B (zh) | 治愈心增大的药物 | |
| CN104435881A (zh) | 一种治疗肾病综合症的药物 | |
| CN103142972A (zh) | 一种治疗小儿皮肤病的药剂 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: TIANJIANG PHARMACEUTICAL INDUSTRY CO., LTD., JIANG Free format text: FORMER OWNER: TIAN MINGXIA Effective date: 20130802 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 272111 JINING, SHANDONG PROVINCE TO: 214400 WUXI, JIANGSU PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20130802 Address after: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee after: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin Address before: 272111 Department of Ophthalmology, the first people's Hospital of Shandong, Jining Province, 6 health Road, Shandong, Jining Patentee before: Tian Mingxia |
|
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Li Peng Inventor before: Tian Mingxia |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170411 Address after: 414000 Yunxi Industrial Park, Yunxi District, Hunan, Yueyang Patentee after: Yueyang Pengcheng Technology Development Co., Ltd. Address before: 214400 Jiangyin Economic Development Zone, Jiangsu, Qin Shan Road, No. 8 Patentee before: Tianjiang Pharmaceutical Industry Co., Ltd., Jiangyin |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130417 Termination date: 20171209 |