CN102485269A - Medicinal composition for food digesting and stomach strengthening and preparation method thereof - Google Patents

Medicinal composition for food digesting and stomach strengthening and preparation method thereof Download PDF

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CN102485269A
CN102485269A CN2010105785363A CN201010578536A CN102485269A CN 102485269 A CN102485269 A CN 102485269A CN 2010105785363 A CN2010105785363 A CN 2010105785363A CN 201010578536 A CN201010578536 A CN 201010578536A CN 102485269 A CN102485269 A CN 102485269A
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parts
concentrated solution
obtains
fructus
stomach
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潘勤
李燕钰
闫晓楠
宋立平
李侠
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Tianjin Darentang Pharmaceutical Factory Zhongxin Pharmaceutical Group Co Ltd
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Tianjin Darentang Pharmaceutical Factory Zhongxin Pharmaceutical Group Co Ltd
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Abstract

The invention which discloses a medicinal composition for food digesting and stomach strengthening and a preparation method thereof belongs to the traditional Chinese medicine modernization field. Active components of the medicinal composition for food digesting and stomach strengthening are prepared from the following raw materials, by weight, 200 parts of medicated leaven (stir-fried with bran), 200 parts of haw, 200 parts of (fried) radish seed, 200 parts of Poria cocos, 200 parts of dried orange peel, 200 parts of Weeping Forsythia, 200 parts of Fructus Aurantii (stir-fried with bran), 200 parts of Fructus Amomi, 120 parts of Pogostemon cablin, 120 parts of Rhizoma Pinelliae Preparata, and 200 parts of cortex magnoliae officinalis (prepared with ginger). The medicinal composition, which has the advantages of stable and controllable quality, curative effect substantially higher than curative effects of present market medicines, and less dosage taken by a patient, has substantial economic and social benefits.

Description

A kind of pharmaceutical composition of promoting digestion and invigorating the stomach and method for preparing
Technical field
The present invention relates to a kind of pharmaceutical composition and method for preparing of promoting digestion and invigorating the stomach, belong to modern Chinese traditional medicine field.
Background technology
The child food digesting stomach fortifying ball is at present commercially available a kind of promoting digestion and purgation, the Chinese medicine of removing dampness to restore normal function of the stomach, and it is processed by Massa Medicata Fermentata (parched with bran), Fructus Crataegi, Semen Raphani (stir-fry), Poria, Pericarpium Citri Reticulatae, Fructus Forsythiae, Fructus Aurantii (parched with bran), Fructus Amomi, Herba Pogostemonis, Rhizoma Pinelliae, Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens).But child food digesting stomach fortifying ball promoting digestion and purgation, removing dampness to restore normal function of the stomach.Be used for meat stagnation, feeling of oppression and fullness in the chest and epigastrium, abdominal distention and pain, belching and acid regurgitation, thick fur and anorexia, loose stool and diarrhea.
Fructus Crataegi, Massa Medicata Fermentata, the Semen Raphani stomach function regulating that helps digestion in the side; Cortex Magnoliae Officinalis, Rhizoma Pinelliae promoting qi circulation, resolving food retention, dissolving lump and resolving mass; Fructus Forsythiae heat clearing away suppressing the hyperactive liver, relieving convulsion relieving restlessness; Pericarpium Citri Reticulatae, Fructus Aurantii, Herba Pogostemonis, Poria, Fructus Amomi regulating QI to expel dampness, stagnant the removing that disappear are expanded.All medicines are harmonious, and play the merit of the intestinal stasis relieving that is good for the stomach altogether.
The food stagnation traditional Chinese medical science is claimed " stagnating " again, belongs to the peculiar name of disease of Pediatrics of Chinese Medicine.It comprises diseases such as the chronic indigestion of modern medicine, slight malnutrition, is the digestive system chronic functional disorder that multiple factor causes.
Food stagnation of child, the traditional Chinese medical science think it mainly is because the food of the greasy savoury of surfeit is built up and do not changed, due to the stagnation of QI is not all right, be also referred to as get ill from overeating, dyspepsia.If malpractice, stagnant with the passing of time delay is lost and is controlled, and the spleen and stomach function grievous injury can cause nutrition and dysplasia and is converted into " infantile malnutrition disease ".
Current society, people's dietary structure, living condition, living environment, family composition have all had very big change, make a lot of spectrum of disease, syndrome spectrum that variation all take place.The children life condition is especially superior, so the spectrum of disease of department of pediatrics has also had very about-face.What supernutrition produced now is stagnant, the major reason of the multiple disease incidence of children's Cheng Liao.After food stagnation forms, injure taste, cause dysfunction of spleen and stomach, a series of digestive system diseases can occur.And stay in the gastrointestinal food stagnation, and become new paathogenic factor again, can bring out multiple pediatric disease.
The prescription of child food digesting stomach fortifying ball and method for making are: Massa Medicata Fermentata (parched with bran) 200g, Fructus Crataegi 200g, Semen Raphani (stir-fry) 200g, Poria 200g, Pericarpium Citri Reticulatae 200g, Fructus Forsythiae 200g, Fructus Aurantii (parched with bran) 200g, Fructus Amomi 200g, Herba Pogostemonis 120g, Rhizoma Pinelliae 120g, Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens) 200g.With ten medical materials simply, be ground into fine powder, sieve mixing.Every 100g powder adds refined honey 130~150g and processes big honeyed pills, promptly gets.
This medicine method for making is simple, but former prescription type is a honeyed pill, goes mouldy easily and microbiological contamination.Take and carry inconvenience, mouthfeel is not good, and every ball weighs 3 grams, and every dose of dose is excessive, and children's's dysphagia is taken inconvenience, and patient's acceptance level is poor.And from oral slow to the gastrointestinal absorption process.These factors directly influence child food digesting stomach fortifying ball applying clinically.
Summary of the invention
First technical problem that the present invention will solve provides a kind of pharmaceutical composition of promoting digestion and invigorating the stomach.
Another technical problem that the present invention will solve provides manufacturing method for above mentioned medicine.
For realizing above-mentioned purpose, the present invention adopts following technical scheme:
A kind of pharmaceutical composition of promoting digestion and invigorating the stomach, its active component is processed by the raw material of following parts by weight: 200 parts of Massa Medicata Fermentatas (parched with bran), 200 parts of Fructus Crataegis, 200 parts of Semen Raphanis (stir-fry), 200 parts in Poria, 200 parts of Pericarpium Citri Reticulataes, 200 parts of Fructus Forsythiaes, 200 parts of Fructus Aurantiis (parched with bran), 200 parts of Fructus Amomis, 120 parts of Herba Pogostemonis, 120 parts of Rhizoma Pinelliae, 200 parts of Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens).
Said active component adopts following method to prepare: take by weighing each raw material by proportioning raw materials, Quan Fangshui carries, and water is carried 2-3 time, extracts 1-3 hour with 6-12 times of water gaging at every turn; Merge extractive liquid, is concentrated into that relative density is 1.03-1.10 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.Dry thing I is the active component of medicine of the present invention.
Said active component adopts following method to prepare: take by weighing each raw material by proportioning raw materials; Quan Fangshui carries, and water is carried 2-3 time, extracts 2-3 hour with 8-10 times of water gaging at every turn; Merge extractive liquid, is concentrated into that relative density is 1.05-1.08 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
Said active component adopts following method to prepare: take by weighing each raw material by proportioning raw materials; Quan Fangshui carries, and water is carried 2 times, extracts 1.5 hours with 10 times of water gagings at every turn; Merge extractive liquid, is concentrated into that relative density is 1.05-1.08 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
Said pharmaceutical composition also contains the pharmaceutics acceptable auxiliary.
Said pharmaceutics acceptable auxiliary is selected from any one or a few in starch, microcrystalline Cellulose, sucrose, aspartame, dextrin, lactose, Icing Sugar, glucose, sodium chloride, sodium carboxymethyl cellulose, crospolyvinylpyrrolidone, magnesium stearate, micropowder silica gel, vitamin C, cysteine, citric acid and the sodium sulfite.
Said Chinese medicine composition is a peroral dosage form, comprises pill, tablet, capsule or oral liquid.The selection of dosage form and the consumption of adjuvant all belong to prior art.
A kind of preparation of drug combination method of promoting digestion and invigorating the stomach takes by weighing 200 parts of Massa Medicata Fermentatas (parched with bran), 200 parts of Fructus Crataegis, 200 parts of Semen Raphanis (stir-fry), 200 parts in Poria, 200 parts of Pericarpium Citri Reticulataes, 200 parts of Fructus Forsythiaes, 200 parts of Fructus Aurantiis (parched with bran), 200 parts of Fructus Amomis, 120 parts of Herba Pogostemonis, 120 parts of Rhizoma Pinelliae, 200 parts of Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens); Quan Fangshui carries, and water is carried 2-3 time, extracts 1-3 hour with 6-12 times of water gaging at every turn; Merge extractive liquid, is concentrated into that relative density is 1.03-1.10 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
Preferred manufacturing procedure is: take by weighing each raw material by proportioning raw materials, Quan Fangshui carries, and water is carried 2-3 time, extracts 2-3 hour with 8-10 times of water gaging at every turn; Merge extractive liquid, is concentrated into that relative density is 1.05-1.08 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
Most preferred method for preparing is: take by weighing each raw material by proportioning raw materials; Quan Fangshui carries, and water is carried 2 times, extracts 1.5 hours with 10 times of water gagings at every turn; Merge extractive liquid, is concentrated into that relative density is 1.05-1.08 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
Chinese medicine composition that technical scheme of the present invention is related and preparation thereof all have good promoting digestion and purgation, removing dampness to restore normal function of the stomach effect.Can be used for treating meat stagnation, feeling of oppression and fullness in the chest and epigastrium, abdominal distention and pain, belching and acid regurgitation, thick fur and anorexia, loose stool and diarrhea.
Through zoopery, we find that unexpectedly the pharmaceutical composition of prepared of the present invention is compared with former dosage form, have more excellent promotion gastrointestinal motility effect.
Advantage of the present invention is: the present invention uses theory of Chinese medical science analysis prescription to form, and according to the physicochemical property and the Pharmacological action study result of each flavour of a drug ingredient, research has obtained the method for preparing of reasonable, stable active component.Adopt technical scheme of the present invention, prepared pharmaceutical preparation stable and controllable for quality, that curative effect is compared with existing commercially available dosage form and significantly improved, patient's taking dose reduces, bioavailability improves, have remarkable economical and social benefit.
Below specify technical scheme of the present invention through embodiment, do not limit practical range of the present invention with this.
The specific embodiment
Embodiment 1: the preparation Chinese medicine extract
One. prescription: Massa Medicata Fermentata (parched with bran) 200g, Fructus Crataegi 200g, Semen Raphani (stir-fry) 200g, Poria 200g, Pericarpium Citri Reticulatae 200g, Fructus Forsythiae 200g, Fructus Aurantii (parched with bran) 200g, Fructus Amomi 200g, Herba Pogostemonis 120g, Rhizoma Pinelliae 120g, Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens) 200g.
Two. method for making:
Take by weighing each raw material by proportioning raw materials, full side carries each 2 hours 2 times with 10 times of amounts, 8 times of water gagings; Merge extractive liquid, is concentrated into that relative density is 1.05 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I 850 grams.Dry thing I is the active component of medicine of the present invention.
Embodiment 2: the preparation Chinese medicine extract
One. prescription: Massa Medicata Fermentata (parched with bran) 2000g, Fructus Crataegi 2000g, Semen Raphani (stir-fry) 2000g, Poria 2000g, Pericarpium Citri Reticulatae 2000g, Fructus Forsythiae 2000g, Fructus Aurantii (parched with bran) 2000g, Fructus Amomi 2000g, Herba Pogostemonis 1200g, Rhizoma Pinelliae 1200g, Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens) 2000g
Two. method for making:
Take by weighing each raw material by proportioning raw materials, full side carries each 3 hours 2 times with 10 times of amounts, 12 times of water gagings; Merge extractive liquid, is concentrated into that relative density is 1.07 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I 1870 grams.Dry thing I is the active component of medicine of the present invention
Embodiment 3: the preparation Chinese medicine extract
One. prescription: Massa Medicata Fermentata (parched with bran) 200g, Fructus Crataegi 200g, Semen Raphani (stir-fry) 200g, Poria 200g, Pericarpium Citri Reticulatae 200g, Fructus Forsythiae 200g, Fructus Aurantii (parched with bran) 200g, Fructus Amomi 200g, Herba Pogostemonis 120g, Rhizoma Pinelliae 120g, Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens) 200g
Two. method for making:
Take by weighing each raw material by proportioning raw materials, full side carries 2 times each 1.5 hours with 10 times of water gagings; Merge extractive liquid, is concentrated into that relative density is 1.08 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I 750 grams.Dry thing I is the active component of medicine of the present invention.
Embodiment 4: the preparation Chinese medicine extract
One. prescription: Massa Medicata Fermentata (parched with bran) 200g, Fructus Crataegi 200g, Semen Raphani (stir-fry) 200g, Poria 200g, Pericarpium Citri Reticulatae 200g, Fructus Forsythiae 200g, Fructus Aurantii (parched with bran) 200g, Fructus Amomi 200g, Herba Pogostemonis 120g, Rhizoma Pinelliae 120g, Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens) 200g
Two. method for making:
Take by weighing each raw material by proportioning raw materials, full side carries 3 times each 1 hour with 8 times of water gagings; Merge extractive liquid, is concentrated into that relative density is 1.10 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I 800 grams.Dry thing I is the active component of medicine of the present invention.
Embodiment 5: the preparation Chinese medicine extract
One. prescription: Massa Medicata Fermentata (parched with bran) 200g, Fructus Crataegi 200g, Semen Raphani (stir-fry) 200g, Poria 200g, Pericarpium Citri Reticulatae 200g, Fructus Forsythiae 200g, Fructus Aurantii (parched with bran) 200g, Fructus Amomi 200g, Herba Pogostemonis 120g, Rhizoma Pinelliae 120g, Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens) 200g
Two. method for making:
Take by weighing each raw material by proportioning raw materials, full side carries 2 times each 2 hours with 6 times of water gagings; Merge extractive liquid, is concentrated into that relative density is 1.03 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I 760 grams.Dry thing I is the active component of medicine of the present invention.
Embodiment 6: the preparation Chinese medicine extract
One. prescription: Massa Medicata Fermentata (parched with bran) 200g, Fructus Crataegi 200g, Semen Raphani (stir-fry) 200g, Poria 200g, Pericarpium Citri Reticulatae 200g, Fructus Forsythiae 200g, Fructus Aurantii (parched with bran) 200g, Fructus Amomi 200g, Herba Pogostemonis 120g, Rhizoma Pinelliae 120g, Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens) 200g
Two. method for making:
Take by weighing each raw material by proportioning raw materials, full side carries 2 times each 1.5 hours with 10 times of water gagings; Merge extractive liquid, is concentrated into that relative density is 1.07 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I750 gram.Dry thing I is the active component of medicine of the present invention.
Embodiment 7: the preparation Chinese medicine extract
One. prescription: Massa Medicata Fermentata (parched with bran) 200g, Fructus Crataegi 200g, Semen Raphani (stir-fry) 200g, Poria 200g, Pericarpium Citri Reticulatae 200g, Fructus Forsythiae 200g, Fructus Aurantii (parched with bran) 200g, Fructus Amomi 200g, Herba Pogostemonis 120g, Rhizoma Pinelliae 120g, Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens) 200g
Two. method for making:
Take by weighing each raw material by proportioning raw materials, full side carries each 2 hours 2 times with 8 times of amounts, 12 times of water gagings; Merge extractive liquid, is concentrated into that relative density is 1.06 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I 690 grams.Dry thing I is the active component of medicine of the present invention.
Embodiment 8: the preparation tablet
The active component 100g that embodiment 1 obtains adds xylitol 50g, dextrin 50g, and aspartame 0.1g, tabletting gets buccal tablet, and every is 0.6g.
Embodiment 9: the preparation granule
The active component 100g that embodiment 2 obtains, with sucrose 80g, dextrin 20g, citric acid 2g, aspartame 0.1g, the system granule gets granule, and every bag is 5g.
Embodiment 10: zoopery one: extract of the present invention is to the influence of mouse small intestine progradation
One. material and method
The child food digesting stomach fortifying ball reaches core hall pharmaceutical factory by new Pharmaceutical limited company in the Tianjin and produces
Animal: the ICR mice is provided credit number by Beijing Vital River Experimental Animals Technology Co., Ltd.: SCXK (capital) 2006-0009.
Cisapride is produced by Xian-Janssen Pharmaceutical Ltd., and carbon powder is produced by Tianjin pharmaceuticals by northization glass purchase and sale center, Tianjin product arabic gum
Get 60 of healthy ICR mices, body weight 18~22g is divided into 6 groups at random, i.e. blank control group, cisapride positive controls, basic, normal, high group of child food digesting stomach fortifying ball group, child food digesting stomach fortifying extract.Dosage is: blank control group is irritated with purified water; Cisapride positive drug group is irritated with 10mg/kg cisapride medicinal liquid; Child food digesting stomach fortifying ball group is irritated with 3g crude drug/kg child food digesting stomach fortifying pill liquid; Basic, normal, high group of child food digesting stomach fortifying extract (preparation of embodiment 3 methods) is irritated with 0.75,1.5 respectively, 3g crude drug/kg child food digesting stomach fortifying extract medicinal liquid, and the administration volume is 20ml/kg, and gastric infusion is 7 days continuously; Fasting is 16 hours before the last administration, and 60 minutes every mouse stomaches only give 5% carbon powder (10% arabic gum) suspension 0.3ml/ after the administration, take off cervical vertebra after 15 minutes and put to death animal; Cut open the belly immediately, separate mesentery, the clip upper end is to pylorus; Lower end to ileocecal intestinal tube; Be tiled on the glass plate, draw gently linearly, measuring intestinal tube length is " small intestinal total length "; From the distance conduct " carbon powder is at the enteral advance distance " in pylorus to carbon powder forward position, calculate and advance percentage rate.
Two. result: see table 1.
Table 1 extract administration seven days is to the propulsive influence of mouse small intestine
Figure BSA00000377863400062
Figure BSA00000377863400063
Compare with the blank group *P<0.05, *P<0.01
The result shows: the child food digesting stomach fortifying extract promotes the propulsive length specification child food digesting stomach fortifying of small intestinal carbon powder extract 1.5, under the dosage of 3g crude drug/kg the good propulsive function of promotion mouse small intestine to be arranged 1.5, under the dosage of 3g crude drug/kg.
Embodiment 11: zoopery two: extract of the present invention is to the influence of mice gastric emptying
One. method:
Get 60 of healthy ICR mices, body weight 18~22g is divided into 6 groups at random, i.e. blank control group, cisapride positive controls, basic, normal, high group of child food digesting stomach fortifying ball group, child food digesting stomach fortifying extract.Dosage is: blank control group is irritated with purified water; Cisapride positive drug group is irritated with 10mg/kg cisapride medicinal liquid; Child food digesting stomach fortifying ball group is irritated with 3g crude drug/kg child food digesting stomach fortifying pill liquid; Basic, normal, high group of child food digesting stomach fortifying extract (preparation of embodiment 3 methods) is irritated with 0.75,1.5 respectively, 3g crude drug/kg child food digesting stomach fortifying extract medicinal liquid; The administration volume is 20ml/kg, and gastric infusion is 7 days continuously, and fasting is 16 hours before the last administration; 60 minutes every mouse stomaches give the semi-solid paste of trophism (by milk powder after the administration; Sugar, starch is formed) 0.8ml/ only, take off cervical vertebra after 20 minutes and put to death mice.Open abdomen and get stomach, claim stomach full weight and net weight, calculate the gastric residue and account for institute to irritate the percentage by weight of semisolid paste be the gastric residual rate.
Figure BSA00000377863400071
Two. result: see table 2.
The table 2 extract successive administration influence to the mice gastric emptying in seven days
Figure BSA00000377863400072
Figure BSA00000377863400073
Compare with the blank group, *P<0.05, *P<0.01
The result shows: the result shows: the child food digesting stomach fortifying extract reduces mice gastric residual quantity 1.5, under the dosage of 3g crude drug/kg, explains that the child food digesting stomach fortifying extract has the function of good promotion mice gastric emptying 1.5, under the dosage of 3g crude drug/kg.

Claims (10)

1. the pharmaceutical composition of a promoting digestion and invigorating the stomach, it is characterized in that: its active component is processed by the raw material of following parts by weight: 200 parts of Massa Medicata Fermentatas (parched with bran), 200 parts of Fructus Crataegis, 200 parts of Semen Raphanis (stir-fry), 200 parts in Poria, 200 parts of Pericarpium Citri Reticulataes, 200 parts of Fructus Forsythiaes, 200 parts of Fructus Aurantiis (parched with bran), 200 parts of Fructus Amomis, 120 parts of Herba Pogostemonis, 120 parts of Rhizoma Pinelliae, 200 parts of Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens).
2. the pharmaceutical composition of a kind of promoting digestion and invigorating the stomach according to claim 1, it is characterized in that said active component adopts following method to prepare: take by weighing each raw material by proportioning raw materials, Quan Fangshui carries, and water is carried 2-3 time, extracts 1-3 hour with 6-12 times of water gaging at every turn; Merge extractive liquid, is concentrated into that relative density is 1.03-1.10 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
3. the pharmaceutical composition of a kind of promoting digestion and invigorating the stomach according to claim 2 is characterized in that: saidly take by weighing each raw material by proportioning raw materials; Quan Fangshui carries, and water is carried 2-3 time, extracts 2-3 hour with 8-10 times of water gaging at every turn; Merge extractive liquid, is concentrated into that relative density is 1.05-1.08 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
4. the pharmaceutical composition of a kind of promoting digestion and invigorating the stomach according to claim 3 is characterized in that: saidly take by weighing each raw material by proportioning raw materials; Quan Fangshui carries, and water is carried 2 times, extracts 1.5 hours with 10 times of water gagings at every turn; Merge extractive liquid, is concentrated into that relative density is 1.05-1.08 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
5. according to the Chinese medicine composition of any one described a kind of promoting digestion and purgation removing dampness to restore normal function of the stomach in the claim 1 to 4, it is characterized in that: said pharmaceutical composition also contains the pharmaceutics acceptable auxiliary.
6. the pharmaceutical composition of a kind of promoting digestion and invigorating the stomach according to claim 5, it is characterized in that: said pharmaceutics acceptable auxiliary is selected from any one or a few in starch, microcrystalline Cellulose, sucrose, aspartame, dextrin, lactose, Icing Sugar, glucose, sodium chloride, sodium carboxymethyl cellulose, crospolyvinylpyrrolidone, magnesium stearate, micropowder silica gel, vitamin C, cysteine, citric acid and the sodium sulfite.
7. the pharmaceutical composition of a kind of promoting digestion and invigorating the stomach according to claim 5, it is characterized in that: said Chinese medicine composition is a peroral dosage form, comprises pill, tablet, capsule or oral liquid.
8. the preparation of drug combination method of the described a kind of promoting digestion and invigorating the stomach of claim 1 is characterized in that: take by weighing 200 parts of Massa Medicata Fermentatas (parched with bran), 200 parts of Fructus Crataegis, 200 parts of Semen Raphanis (stir-fry), 200 parts in Poria, 200 parts of Pericarpium Citri Reticulataes, 200 parts of Fructus Forsythiaes, 200 parts of Fructus Aurantiis (parched with bran), 200 parts of Fructus Amomis, 120 parts of Herba Pogostemonis, 120 parts of Rhizoma Pinelliae, 200 parts of Cortex Magnoliae Officinalis (processed with Rhizoma Zingiberis Recens); Quan Fangshui carries, and water is carried 2-3 time, extracts 1-3 hour with 6-12 times of water gaging at every turn; Merge extractive liquid, is concentrated into that relative density is 1.03-1.10 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
9. the preparation of drug combination method of the described a kind of promoting digestion and invigorating the stomach of claim 8 is characterized in that: saidly take by weighing each raw material by proportioning raw materials, Quan Fangshui carries, and water is carried 2-3 time, extracts 2-3 hour with 8-10 times of water gaging at every turn; Merge extractive liquid, is concentrated into that relative density is 1.05-1.08 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
10. the preparation of drug combination method of the described a kind of promoting digestion and invigorating the stomach of claim 9 is characterized in that: saidly take by weighing each raw material by proportioning raw materials; Quan Fangshui carries, and water is carried 2 times, extracts 1.5 hours with 10 times of water gagings at every turn; Merge extractive liquid, is concentrated into that relative density is 1.05-1.08 under the 50-60 ℃ of condition, obtains concentrated solution A, and concentrated solution A is dry, obtains dry thing I.
CN2010105785363A 2010-12-03 2010-12-03 Medicinal composition for food digesting and stomach strengthening and preparation method thereof Pending CN102485269A (en)

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CN102698173A (en) * 2012-06-15 2012-10-03 李良 Medicated leaven Chinese medicinal decoction for treating abdominal pain and preparation method thereof
CN113559192A (en) * 2021-07-30 2021-10-29 北京斯利安健康科技有限公司 Digestion-aiding powder suitable for loss of appetite

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CN1785397A (en) * 2005-07-28 2006-06-14 江西汇仁药业有限公司 Child food digesting stomach fortifying fast dispersion solid preparation and its preparation method

Cited By (3)

* Cited by examiner, † Cited by third party
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CN102698173A (en) * 2012-06-15 2012-10-03 李良 Medicated leaven Chinese medicinal decoction for treating abdominal pain and preparation method thereof
CN102698173B (en) * 2012-06-15 2013-10-09 李良 Medicated leaven Chinese medicinal decoction for treating abdominal pain and preparation method thereof
CN113559192A (en) * 2021-07-30 2021-10-29 北京斯利安健康科技有限公司 Digestion-aiding powder suitable for loss of appetite

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Application publication date: 20120606