CN102481353B - 用作疫苗的金黄色葡萄球菌DivIB - Google Patents

用作疫苗的金黄色葡萄球菌DivIB Download PDF

Info

Publication number
CN102481353B
CN102481353B CN201080039459.2A CN201080039459A CN102481353B CN 102481353 B CN102481353 B CN 102481353B CN 201080039459 A CN201080039459 A CN 201080039459A CN 102481353 B CN102481353 B CN 102481353B
Authority
CN
China
Prior art keywords
polypeptide
vaccine
infection
nucleotide sequence
staphylococcus aureus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080039459.2A
Other languages
English (en)
Chinese (zh)
Other versions
CN102481353A (zh
Inventor
J·加西亚拉腊
S·福斯特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Absynth Biologics Ltd
Original Assignee
Absynth Biologics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Absynth Biologics Ltd filed Critical Absynth Biologics Ltd
Publication of CN102481353A publication Critical patent/CN102481353A/zh
Application granted granted Critical
Publication of CN102481353B publication Critical patent/CN102481353B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201080039459.2A 2009-10-09 2010-09-13 用作疫苗的金黄色葡萄球菌DivIB Expired - Fee Related CN102481353B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0917685.0 2009-10-09
GBGB0917685.0A GB0917685D0 (en) 2009-10-09 2009-10-09 Antigenic polypeptide
PCT/GB2010/001722 WO2011042681A1 (en) 2009-10-09 2010-09-13 Staphylococcus aureus divi1b for use as vaccine

Publications (2)

Publication Number Publication Date
CN102481353A CN102481353A (zh) 2012-05-30
CN102481353B true CN102481353B (zh) 2015-01-14

Family

ID=41402763

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080039459.2A Expired - Fee Related CN102481353B (zh) 2009-10-09 2010-09-13 用作疫苗的金黄色葡萄球菌DivIB

Country Status (8)

Country Link
US (2) US8691242B2 (https=)
EP (1) EP2485757A1 (https=)
JP (1) JP5963674B2 (https=)
CN (1) CN102481353B (https=)
AU (1) AU2010304915B2 (https=)
CA (1) CA2775997A1 (https=)
GB (1) GB0917685D0 (https=)
WO (1) WO2011042681A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201206366D0 (en) * 2012-04-11 2012-05-23 Absynth Biologics Ltd Bacterial vaccine
GB201417214D0 (en) 2014-09-30 2014-11-12 Absynth Biologics Ltd Vaccine
CN116904356A (zh) * 2022-06-22 2023-10-20 浙江省农业科学院 模仿葡萄球菌hz01菌剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002094868A2 (en) * 2001-03-27 2002-11-28 Chiron Srl. Staphylococcus aureus proteins and nucleic acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6022706A (en) * 1997-04-09 2000-02-08 Smithkline Beecham Corporation Div1b
US5955304A (en) * 1997-01-02 1999-09-21 Smithkline Beecham Corporation DivIB
AU2002306849A1 (en) * 2001-03-21 2002-10-08 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
ES2504166T3 (es) * 2002-09-13 2014-10-08 Novartis Vaccines And Diagnostics, Inc. Vacuna de estreptococo del grupo B
GB0409559D0 (en) * 2004-04-29 2004-06-02 Univ Sheffield Polypeptide
GB0505949D0 (en) * 2005-03-23 2005-04-27 Univ Sheffield Polypeptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002094868A2 (en) * 2001-03-27 2002-11-28 Chiron Srl. Staphylococcus aureus proteins and nucleic acids

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Anti-Staphylococcus aureus immunotherapy:current status and prospects;JORGE ET AL;《CURRENT OPINION IN PHARMACOLOGY》;20090903;第9卷(第5期);全文 *
Straphylococcus aureus:the search for novel targets;GARCIA-LARA J ET AL;《Drug discovery today》;20050501;第9卷(第10期);全文 *

Also Published As

Publication number Publication date
AU2010304915B2 (en) 2014-06-12
US20120195920A1 (en) 2012-08-02
JP5963674B2 (ja) 2016-08-03
US8691242B2 (en) 2014-04-08
AU2010304915A1 (en) 2012-03-22
GB0917685D0 (en) 2009-11-25
EP2485757A1 (en) 2012-08-15
JP2013507116A (ja) 2013-03-04
WO2011042681A1 (en) 2011-04-14
CA2775997A1 (en) 2011-04-14
US20140161835A1 (en) 2014-06-12
CN102481353A (zh) 2012-05-30

Similar Documents

Publication Publication Date Title
CN118480136B (zh) 一种预防和治疗金黄色葡萄球菌感染的免疫原性组合物
CN102481353B (zh) 用作疫苗的金黄色葡萄球菌DivIB
CN102292104A (zh) 用于诱导抗金黄色葡萄球菌的保护性免疫应答的多肽
CN102292105A (zh) 用于诱导抗金黄色葡萄球菌的保护性免疫应答的多肽
US8124108B2 (en) Polypeptides for inducing a protective immune response against Staphylococcus epidermidis
US9233150B2 (en) Combination vaccine
CN101636493A (zh) 用于诱导针对表皮葡萄球菌的保护性免疫反应的多肽
JP2015515486A (ja) 抗原および抗原の組み合わせ
ES2369087T3 (es) Phep, una permeasa de aminoácido de staphylococcus aureus.
US9610341B2 (en) Bacterial vaccine
RU2285539C2 (ru) Молекулярная бивалентная вакцина для профилактики бруцеллеза и диарей, вызванных энтеропатогенными бактериями

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150114

Termination date: 20170913