CN102448484A - 调节角质化细胞增生和分化的方法 - Google Patents

调节角质化细胞增生和分化的方法 Download PDF

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Publication number
CN102448484A
CN102448484A CN2010800240522A CN201080024052A CN102448484A CN 102448484 A CN102448484 A CN 102448484A CN 2010800240522 A CN2010800240522 A CN 2010800240522A CN 201080024052 A CN201080024052 A CN 201080024052A CN 102448484 A CN102448484 A CN 102448484A
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China
Prior art keywords
igfbp7
keratinocytes
expression
cells
polypeptide
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Pending
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CN2010800240522A
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English (en)
Chinese (zh)
Inventor
埃利·施普雷舍尔
简纳·努斯贝克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rappaport Family Institute for Research in the Medical Sciences
Medical Research Infrastructure and Health Services Fund of the Tel Aviv Medical Center
Original Assignee
Rappaport Family Institute for Research in the Medical Sciences
Medical Research Infrastructure and Health Services Fund of the Tel Aviv Medical Center
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Publication of CN102448484A publication Critical patent/CN102448484A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CN2010800240522A 2009-04-01 2010-02-28 调节角质化细胞增生和分化的方法 Pending CN102448484A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20276009P 2009-04-01 2009-04-01
US61/202,760 2009-04-01
PCT/IL2010/000167 WO2010113146A1 (en) 2009-04-01 2010-02-28 A method of regulating proliferation and differentiation of keratinocyes

Publications (1)

Publication Number Publication Date
CN102448484A true CN102448484A (zh) 2012-05-09

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CN2010800240522A Pending CN102448484A (zh) 2009-04-01 2010-02-28 调节角质化细胞增生和分化的方法

Country Status (8)

Country Link
US (1) US8912142B2 (https=)
EP (1) EP2344179A1 (https=)
JP (1) JP2012522762A (https=)
CN (1) CN102448484A (https=)
AU (1) AU2010231514A1 (https=)
CA (1) CA2759201A1 (https=)
MX (1) MX2011010401A (https=)
WO (1) WO2010113146A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107881240A (zh) * 2017-12-27 2018-04-06 北京泱深生物信息技术有限公司 骨肉瘤的诊治标志物
CN109689867A (zh) * 2016-07-02 2019-04-26 富荣吉有限责任公司 利用基于肌动蛋白的肽调节细胞生物活性和细胞对胞内病原体易感性的组合物和方法
CN115212302A (zh) * 2022-08-03 2022-10-21 中国人民解放军空军军医大学 抗igfbp7抗体在治疗皮肤病中的应用

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AU2010231514A1 (en) 2009-04-01 2011-11-03 Rappaport Family Institute For Research In The Medical Sciences A method of regulating proliferation and differentiation of keratinocytes
US20130123647A1 (en) 2011-05-03 2013-05-16 The Research Foundation Of State University Of New York Methods Useful in Optimizing the Treatment of Neuropathies and Targeting Tissues with Cosmetic Botulinum Injections
US9687669B2 (en) 2011-11-09 2017-06-27 John Stephan Wearable light therapy apparatus
JP6273272B2 (ja) * 2012-07-04 2018-01-31 ジージー バイオテック エルエルシー 炎症性皮膚障害の治療
DE102013213252A1 (de) * 2013-07-05 2015-01-08 Schülke & Mayr GmbH Verwendung eines Isopropanol enthaltenden Mittels zur Bekämpfung von Caliciviridae
EP3113849B1 (en) * 2014-02-26 2019-06-12 Luma Therapeutics, Inc. Ultraviolet phototherapy apparatus
US20190083809A1 (en) 2016-07-27 2019-03-21 Z2020, Llc Componentry and devices for light therapy delivery and methods related thereto
US11147618B2 (en) 2017-01-11 2021-10-19 Medtronic Advanced Energy Llc Electrosurgical unit and system
GB201808723D0 (en) * 2018-05-29 2018-07-11 Univ Birmingham Treatment of hyperproliferative disorders
SG11202108022RA (en) 2019-01-30 2021-08-30 Agency Science Tech & Res Use of igfbp7 for treating malaria
US20230022117A1 (en) * 2019-12-04 2023-01-26 Musc Foundation For Research Development RNAi-BASED TARGETING COMPOUNDS AND USES THEREOF TO PREVENT ACQUIRED HEARING LOSS
KR102453894B1 (ko) * 2020-09-15 2022-10-11 (주)아모레퍼시픽 캄페롤 배당체 화합물을 포함하는 피부 보호용 조성물
EP4454663A4 (en) * 2021-12-21 2026-04-08 Univ Tokyo THERAPEUTIC OR PROPHYLACTIC AGENT FOR HEART ATTACK, CARDIAC FIBROSIS OR HEART FAILURE, IN WHICH HTRA3 IS THE THERAPEUTIC TARGET

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109689867A (zh) * 2016-07-02 2019-04-26 富荣吉有限责任公司 利用基于肌动蛋白的肽调节细胞生物活性和细胞对胞内病原体易感性的组合物和方法
CN107881240A (zh) * 2017-12-27 2018-04-06 北京泱深生物信息技术有限公司 骨肉瘤的诊治标志物
CN107881240B (zh) * 2017-12-27 2018-10-02 北京泱深生物信息技术有限公司 骨肉瘤的诊治标志物
CN115212302A (zh) * 2022-08-03 2022-10-21 中国人民解放军空军军医大学 抗igfbp7抗体在治疗皮肤病中的应用

Also Published As

Publication number Publication date
MX2011010401A (es) 2012-01-20
WO2010113146A1 (en) 2010-10-07
JP2012522762A (ja) 2012-09-27
US20110207665A1 (en) 2011-08-25
AU2010231514A1 (en) 2011-11-03
US8912142B2 (en) 2014-12-16
EP2344179A1 (en) 2011-07-20
CA2759201A1 (en) 2010-10-07

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Application publication date: 20120509