CN102423429A

CN102423429A - Small intestine and large intestine two-channel non-exterior relieving traditional Chinese medicine injection and production method

Info

Publication number: CN102423429A
Application number: CN2011104150860A
Authority: CN
Inventors: 王建友
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-12-08
Filing date: 2011-12-08
Publication date: 2012-04-25

Abstract

A small intestine and large intestine two-channel non-exterior relieving traditional Chinese medicine injection and a production method. The formula comprises 1 g of common lophatherum herbs, 0.5 g of commelina communis, 1 g of scutellaria baicalensis, 0.5 g of coptis chinensis, 0.5 g of fructus forsythiae, 1 g of oldenlandia diffusa, 1 g of semen pruni, 1 g of mangnolia officinalis, 1 g of mole cricket, 0.5 g of pepper, 1 g of pericarpium arecae, 1 g of chicken gizzard membrane, 1 g of sophora flowers, 1 g of snakegourd fruits, 1 g of semen boitae, 1 g of honey, 1 g of cynomorium songaricum, 1 g of walnut kernels, 1 g of black sesame, and 1 g of hedgehog hide; the production links comprise: material preparation, cleaning treatment, drying and sterilization, crushing, cell breakage, multiple filtration, filling, rubber plug filling, cover pressing, lamp detection, specification pasting, packaging, storage, and examination; the injection has the advantage that the injection does not need decoction, does not pass through digestive tracts, and does not pass through hair pores or sweat pores, and is applicable to the treatment of patients with hyperhidrosis, polyuria, multiple stagnation caused by tissue diseases of the two channels of the small intestine channel and the large intestine channel; and the production can ensure all the medicinal components in the traditional Chinese medicine prescription, and is production for a small intestine and large intestine two-channel prescription traditional Chinese medicine all-medicine injection.

Description

Small intestinal, large intestine two are through non-Chinese medicine injection and the production method of inducing sweat

Technical field the present invention relates to a kind of not through inducing sweat, can treat small intestinal, large intestine two Chinese medicine injection and the production method through tissue disease.

Background technology is known do not need high temperature decoct, need not be through digestive tract, can treat small intestinal, large intestine two through the Chinese medicine of tissue disease inducing sweat property all; These Chinese medicines are through being got in the human body by pore, pore the inducing sweat effect of pore, pore; And then human small intestine, large intestine two treated through tissue disease; It can bring hyperhidrosis, polyuria, phenomenon such as stagnate more, thereby it is not suitable for the patient of hyperhidrosis, polyuria, symptoms such as stagnate more.

Summary of the invention the object of the invention is exactly in order to solve the shortcoming that above-mentioned Chinese medicine exists, and provide a kind of and need not decoct, not need through digestive tract, not need to the inducing sweat of pore, pore, can direct injection to intravenous, can treat small intestinal, large intestine two Chinese medicine injection and production method through tissue disease.

Chinese medicine preparation of the present invention is: Herba Lophatheri 1g, Herba Commelinae 0.5g, Radix Scutellariae 1g, Rhizoma Coptidis 0.5g, Fructus Forsythiae 0.5g, Herba Hedyotidis Diffusae 1g, Semen Pruni 1g, Cortex Magnoliae Officinalis 1g, Gryllotalpa 1g, Fructus Piperis 0.5g, Pericarpium Arecae 1g, Endothelium Corneum Gigeriae Galli 1g, Flos Sophorae 1g, Fructus Trichosanthis 1g, Semen Platycladi 1g, Mel 1g, Herba Cynomorii 1g, Semen Juglandis 1g, Semen Sesami Nigrum 1g, Corium Erinacei Seu Hemiechianus 1g, production link of the present invention comprise batching, cleaningization processing, drying and sterilizing, flour, cell rupture, multi-filtering, fill, filler plug, gland, lamp inspection, subsides description, packing, storage, check etc., and house of the present invention, facility, equipment comprise: a, batching use the room, prepare burden with equipment such as electronic scale, b, cleaningization processing room are arranged in the room; Equipment such as ultrasonic washing unit are arranged in the cleaningization processing room, and c, drying and sterilizing are used the room, and drying and sterilizing is with there being equipment such as microwave drying room in the room, and d, flour are used the room, and flour is with equipment such as Chinese medicine powder beater are arranged in the room; E, cell rupture are used the room, and cell rupture is with there being equipment such as ultrasonic cell disruptor in the room, and there are equipment such as particulate filter, liquid medicine filter, g, fill room in f, multi-filtering room in the multi-filtering room; Equipment such as automatic filling machine are arranged in the fill room, and there are equipment such as automatic filler plug machine in h, filler plug room in the filler plug room, and there are equipment such as automatic capping machine in i, gland room in the gland room; There are equipment such as computer lamp inspection machine in j, lamp inspection room in the lamp inspection room, k, paste the explanation study, and pasting in the explanation study has the equipment that pastes description, l, packing room; Equipment such as automatic packing machine are arranged in the packing room, m, warehouse, n, check room, concrete production method is: in batch house, take by weighing the various Chinese medicines in the above-mentioned prescription in proportion with electronic scale, various Chinese medicines are rubbed with the hands and are mixed; Be placed in the container, reached in the ultrasonic washing unit in the cleaningization processing room by conveyer belt, and in ultrasonic washing unit, pour pure water into, Chinese medicine is fully immersed in the pure water, opens ultrasonic washing unit; Clean after 20-30 minute, pour out pure water, put into distilled water again, Chinese medicine is carried out fine purifiation; After the Chinese medicine fine purifiation is clean, refund in the clean container, be sent in the microwave drying room in the drying and sterilizing room, the temperature in microwave drying room is transferred to 60 ℃ by conveyer belt; Open, drying and sterilizing is after 24 hours again, and Chinese medicine is reached in the Chinese medicine powder beater in the flour room by conveyer belt, opens; Repeat to pulverize 3-5 time, Chinese medicine is ground into Chinese medicine medicated powder, is sent to cell rupture with in the ultrasonic cell disruptor in the room by conveyer belt again, and pours distilled water in a small amount into; Open ultrasonic cell disruptor, after 24 hours, Chinese medicine cell rupture, intracellular matter dissolve in the water; Pour the distilled water of requirement again into, process middle drug solns, be sent in the multi-filtering room by pipeline again, through the multi-filtering of particulate filter, liquid medicine filter; Filtered granule in the middle drug solns, broken cell wall, and some antibacterials, virus, insoluble substance, middle drug solns has just become Chinese medicine injection, in pipeline is sent to the fill room, carries out fill by automatic filling machine again; After in Chinese medicine injection fill to the infusion bottle, mouth of infusion bottle is sealed by plastic sheeting, is transferred in the filler plug room by conveyer belt again, on plastic sheeting, fills in plug by automatic filler plug machine; And then be sent to the gland room by conveyer belt, and by automatic capping machine easy-open lid is covered on plug, be sent in the lamp inspection room by conveyer belt again, carry out lamp inspection by computer lamp inspection machine; Qualified products are reached by conveyer belt and paste in the explanation study, paste the Chinese medicine description that has lot number, are reached in the packing room, after the vanning by conveyer belt again; By the automatic packing machine packing, send into storehouse reservation again after packing is good, the inspection machine in the check room is tested to each link in this process, and each link in this process all meets the requirement of GMP.

Compare through the Chinese medicine of tissue with present treatment small intestinal, large intestine two; It with non-inducing sweat property small intestinal, large intestine two through medicine, process injection and replace, make it to be applicable to treatment hyperhidrosis, polyuria, the small intestinal that stagnates, large intestine two patient through tissue disease more, decoct without high temperature; Do not pass through digestive tract; Through pore, pore, its production can be saved all pharmaceutical compositions in the Chinese medicine from damage, is the production through the full medicine injection of prescription Chinese medicine of a kind of small intestinal, large intestine two.

Specific embodiment production of the present invention is the production through the full medicine injection of prescription Chinese medicine of a kind of small intestinal, large intestine two, and production of the present invention is the improvement of present Chinese medicine injection production on prescription and method for distilling, and prescription of the present invention is: Herba Lophatheri 1g, Herba Commelinae 0.5g, Radix Scutellariae 1g, Rhizoma Coptidis 0.5g, Fructus Forsythiae 0.5g, Herba Hedyotidis Diffusae 1g, Semen Pruni 1g, Cortex Magnoliae Officinalis 1g, Gryllotalpa 1g, Fructus Piperis 0.5g, Pericarpium Arecae 1g, Endothelium Corneum Gigeriae Galli 1g, Flos Sophorae 1g, Fructus Trichosanthis 1g, Semen Platycladi 1g, Mel 1g, Herba Cynomorii 1g, Semen Juglandis 1g, Semen Sesami Nigrum 1g, Corium Erinacei Seu Hemiechianus 1g, production link of the present invention comprise batching, cleaningization processing, drying and sterilizing, flour, cell rupture, multi-filtering, fill, filler plug, gland, lamp inspection, subsides description, packing, storage, check etc., and house of the present invention, facility, equipment comprise: a, batching are used the room; Batching is with there being equipment such as electronic scale in the room, there are equipment such as ultrasonic washing unit in b, cleaningization processing room in the cleaningization processing room, and c, drying and sterilizing are used the room, and drying and sterilizing is with equipment such as microwave drying room is arranged in the room; D, flour are used the room, and flour is with there being equipment such as Chinese medicine powder beater in the room, and e, cell rupture are used the room, and cell rupture is with equipment such as ultrasonic cell disruptor, f, multi-filtering room are arranged in the room; Particulate filter, the aperture equipment such as liquid medicine filter less than 2um are arranged in the multi-filtering room, and there are equipment such as automatic filling machine in g, fill room in the fill room, and there are equipment such as automatic filler plug machine in h, filler plug room in the filler plug room; There are equipment such as automatic capping machine in i, gland room in the gland room, there are equipment such as computer lamp inspection machine in j, lamp inspection room in the lamp inspection room, k, subsides explanation study; Pasting in the explanation study has the equipment that pastes description, and there are equipment such as automatic packing machine in l, packing room, m, warehouse, n, check room in the packing room; These rooms all are clean rooms, and structure meets the related request of GMP, in batch house, take by weighing the various Chinese medicines in the above-mentioned prescription in proportion with electronic scale, and various Chinese medicines are rubbed with the hands and mixed, and are placed in the container; Reached in the ultrasonic washing unit in the cleaningization processing room by conveyer belt, and in ultrasonic washing unit, pour pure water into, Chinese medicine is fully immersed in the pure water, opens ultrasonic washing unit, cleans after 20-30 minute; Pour out pure water, put into distilled water again, Chinese medicine is carried out fine purifiation, after the Chinese medicine fine purifiation is clean, refund in the clean container; Be sent in the microwave drying room in the drying and sterilizing room by conveyer belt, the temperature in microwave drying room is transferred to 60 ℃, open, drying and sterilizing is after 24 hours, and Chinese medicine is reached in the Chinese medicine powder beater in the flour room by conveyer belt; Open, repeat to pulverize 3-5 time, Chinese medicine is ground into Chinese medicine medicated powder, is sent to cell rupture with in the ultrasonic cell disruptor in the room by conveyer belt again, and pours distilled water in a small amount into; Open ultrasonic cell disruptor, after 24 hours, Chinese medicine cell rupture, intracellular matter dissolve in the water; Pour the distilled water of requirement again into, process middle drug solns, be sent in the multi-filtering room by pipeline again, through the multi-filtering of particulate filter, liquid medicine filter; Filtered granule in the middle drug solns, broken cell wall, and some antibacterials, virus, insoluble substance, middle drug solns has just become Chinese medicine injection, in pipeline is sent to the fill room, carries out fill by automatic filling machine again; After in Chinese medicine injection fill to the infusion bottle, mouth of infusion bottle is sealed by plastic sheeting, is transferred in the filler plug room by conveyer belt again, on plastic sheeting, fills in plug by automatic filler plug machine; And then be sent to the gland room by conveyer belt, and by automatic capping machine easy-open lid is covered on plug, be sent in the lamp inspection room by conveyer belt again, carry out lamp inspection by computer lamp inspection machine; Qualified products are reached by conveyer belt and paste in the explanation study, paste the Chinese medicine description that has lot number, are reached in the packing room, after the vanning by conveyer belt again; By the automatic packing machine packing, send into storehouse reservation again after packing is good, the inspection machine in the check room is tested to each link in this process, and each link in this process all meets the requirement of GMP.

Claims

1. small intestinal, large intestine two are through non-Chinese medicine injection and the production method of inducing sweat, and prescription is: Herba Lophatheri 1g, Herba Commelinae 0.5g, Radix Scutellariae 1g, Rhizoma Coptidis 0.5g, Fructus Forsythiae 0.5g, Herba Hedyotidis Diffusae 1g, Semen Pruni 1g, Cortex Magnoliae Officinalis 1g, Gryllotalpa 1g, Fructus Piperis 0.5g, Pericarpium Arecae 1g, Endothelium Corneum Gigeriae Galli 1g, Flos Sophorae 1g, Fructus Trichosanthis 1g, Semen Platycladi 1g, Mel 1g, Herba Cynomorii 1g, Semen Juglandis 1g, Semen Sesami Nigrum 1g, Corium Erinacei Seu Hemiechianus 1g, and production link comprises: batching, cleaningization processing, drying and sterilizing, flour, cell rupture, multi-filtering, fill, filler plug, gland, lamp inspection, subsides description, packing, storage, check, house and equipment comprise: a, batching are used the room, and batching is with electronic scale is arranged in the room; B, cleaningization processing room, the cleaningization processing has ultrasonic washing unit in the room, and c, drying and sterilizing are used the room, and drying and sterilizing is with there being the microwave drying room in the room, and d, flour are used the room; Flour is with there being the Chinese medicine powder beater in the room, e, cell rupture are used the room, and cell rupture is with there being ultrasonic cell disruptor in the room, and there are particulate filter, liquid medicine filter in f, multi-filtering room in the multi-filtering room; G, fill room, fill has automatic filling machine in the room, and there is automatic filler plug machine in h, filler plug room, i, gland room in the filler plug room; Gland has automatic capping machine in the room, and there is computer lamp inspection machine in j, lamp inspection room in the lamp inspection room, k, subsides explanation study, and pasting in the explanation study has the equipment that pastes description; L, packing room, packing has automatic packing machine in the room, m, warehouse, n, check room is characterized in that: in batch house, take by weighing the various Chinese medicines in the above-mentioned prescription in proportion with electronic scale; Various Chinese medicines are rubbed with the hands and are mixed, and are placed in the container, are reached in the ultrasonic washing unit in the cleaningization processing room by conveyer belt, and in ultrasonic washing unit, pour pure water into, and Chinese medicine is fully immersed in the pure water; Open ultrasonic washing unit, clean after 20-30 minute, pour out pure water, put into distilled water again, Chinese medicine is carried out fine purifiation; After the Chinese medicine fine purifiation is clean, refund in the clean container, be sent in the microwave drying room in the drying and sterilizing room, the temperature in microwave drying room is transferred to 60 ℃ by conveyer belt; Open, drying and sterilizing is after 24 hours again, and Chinese medicine is reached in the Chinese medicine powder beater in the flour room by conveyer belt, opens; Repeat to pulverize 3-5 time, Chinese medicine is ground into Chinese medicine medicated powder, is sent to cell rupture with in the ultrasonic cell disruptor in the room by conveyer belt again, and pours distilled water in a small amount into; Open ultrasonic cell disruptor, after 24 hours, Chinese medicine cell rupture, intracellular matter dissolve in the water; Pour the distilled water of requirement again into, process middle drug solns, be sent in the multi-filtering room by pipeline again, through the multi-filtering of particulate filter, liquid medicine filter; Filtered granule in the middle drug solns, broken cell wall, and some antibacterials, virus, insoluble substance, middle drug solns has just become Chinese medicine injection, in pipeline is sent to the fill room, carries out fill by automatic filling machine again; After in Chinese medicine injection fill to the infusion bottle, mouth of infusion bottle is sealed by plastic sheeting, is transferred in the filler plug room by conveyer belt again, on plastic sheeting, fills in plug by automatic filler plug machine; And then be sent to the gland room by conveyer belt, and by automatic capping machine easy-open lid is covered on plug, be sent in the lamp inspection room by conveyer belt again, carry out lamp inspection by computer lamp inspection machine; Qualified products are reached by conveyer belt and paste in the explanation study, paste the Chinese medicine description that has lot number, are reached in the packing room, after the vanning by conveyer belt again; By the automatic packing machine packing, send into storehouse reservation again after packing is good, the inspection machine in the check room is tested to each link in this process, and each link in this process all meets the requirement of GMP.