CN102413854B - 剂量设定机构 - Google Patents

剂量设定机构 Download PDF

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Publication number
CN102413854B
CN102413854B CN200980158951.9A CN200980158951A CN102413854B CN 102413854 B CN102413854 B CN 102413854B CN 200980158951 A CN200980158951 A CN 200980158951A CN 102413854 B CN102413854 B CN 102413854B
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CN
China
Prior art keywords
dose
far
distal
housing
intended
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Active
Application number
CN200980158951.9A
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English (en)
Chinese (zh)
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CN102413854A (zh
Inventor
A.威塞尔布拉德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Estral Medical Co
Original Assignee
SHL Medical AB
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Publication of CN102413854A publication Critical patent/CN102413854A/zh
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Publication of CN102413854B publication Critical patent/CN102413854B/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A61M2005/3126—Specific display means related to dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536—Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • A61M2005/3154—Blocking means to immobilize a selected dose, e.g. to administer equal doses limiting maximum permissible dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31561—Mechanically operated dose setting member using freely adjustable volume steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN200980158951.9A 2009-02-26 2009-07-31 剂量设定机构 Active CN102413854B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15576509P 2009-02-26 2009-02-26
US61/155,765 2009-02-26
PCT/EP2009/059963 WO2010097125A1 (en) 2009-02-26 2009-07-31 Dose setting mechanism

Publications (2)

Publication Number Publication Date
CN102413854A CN102413854A (zh) 2012-04-11
CN102413854B true CN102413854B (zh) 2013-08-28

Family

ID=41611266

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980158951.9A Active CN102413854B (zh) 2009-02-26 2009-07-31 剂量设定机构

Country Status (10)

Country Link
US (1) US8372042B2 (enExample)
EP (1) EP2401010B1 (enExample)
CN (1) CN102413854B (enExample)
AU (1) AU2009341040B2 (enExample)
DK (1) DK2401010T3 (enExample)
ES (1) ES2672668T3 (enExample)
NO (1) NO2401010T3 (enExample)
PL (1) PL2401010T3 (enExample)
TR (1) TR201807257T4 (enExample)
WO (1) WO2010097125A1 (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0307589A (pt) 2002-02-11 2005-02-01 Antares Pharma Inc Dispositivo de injeção intradérmica
DK3590569T3 (da) 2004-12-31 2021-04-06 Ypsomed Ag Apparat til doseret levering af et flydende produkt med adskillelsesmulighed for skift af beholder
DE102004063645A1 (de) 2004-12-31 2006-07-20 Tecpharma Licensing Ag Vorrichtung zur dosierten Verabreichung eines fluiden Produkts mit Entkopplung für einen Behältniswechsel
EP3495009B2 (en) 2005-01-24 2025-01-15 Antares Pharma, Inc. An injector with prefilled syringe
WO2007131025A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Injector with adjustable dosing
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
JP5731829B2 (ja) 2008-03-10 2015-06-10 アンタレス・ファーマ・インコーポレーテッド 注射器安全装置
AU2009279719B2 (en) 2008-08-05 2015-07-23 Antares Pharma, Inc. Multiple dosage injector
ES2988196T3 (es) 2009-03-20 2024-11-19 Antares Pharma Inc Sistema de inyección de agentes peligrosos
WO2010140974A1 (en) * 2009-06-05 2010-12-09 Shl Group Ab Medicament delivery device
GB0918145D0 (en) 2009-10-16 2009-12-02 Owen Mumford Ltd Injector apparatus
SG186865A1 (en) 2010-07-02 2013-02-28 Carebay Holding Ltd Company No 681498 Preservative-free follicle stimulating hormone solution delivery device
AU2011347652B2 (en) * 2010-12-21 2015-03-26 Sanofi-Aventis Deutschland Gmbh Injection device with dose setting mechanism having maximum dose stop
ES2871477T3 (es) * 2011-05-19 2021-10-29 Becton Dickinson Co Dispositivo de inyección con varias ventanas de ajuste de dosis
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
CN103974732B (zh) * 2011-12-14 2016-08-24 诺沃—诺迪斯克有限公司 具有包括大数字码的机械剂量显示部的注射笔
PT2822618T (pt) 2012-03-06 2024-03-04 Antares Pharma Inc Seringa pré-cheia com característica de força de rutura
US9950125B2 (en) 2012-04-06 2018-04-24 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
WO2013169800A1 (en) 2012-05-07 2013-11-14 Antares Pharma, Inc. Injection device with cammed ram assembly
EP2953667B1 (en) 2013-02-11 2019-10-23 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
ES2742046T3 (es) 2013-03-11 2020-02-12 Antares Pharma Inc Inyector de dosis con sistema de piñón
WO2014165136A1 (en) 2013-03-12 2014-10-09 Antares Pharma, Inc. Constant volume prefilled syringes and kits thereof
US10099015B2 (en) * 2013-04-10 2018-10-16 Sanofi Drive mechanism for a drug delivery device
WO2014166920A1 (en) * 2013-04-10 2014-10-16 Sanofi Drive mechanism for a drug delivery device
CN105530970B (zh) * 2013-09-10 2021-04-06 赛诺菲 用于药物输送装置的剂量指示机构
DE202014001135U1 (de) * 2014-02-05 2015-05-06 Haselmeier Gmbh Injektionsgerät
DE202014001136U1 (de) * 2014-02-05 2015-05-06 Haselmeier Gmbh Injektionsgerät
US10589032B2 (en) * 2014-05-26 2020-03-17 Sanofi Display arrangement for an injection device
CN106413780B (zh) * 2014-05-28 2020-07-10 赛诺菲-安万特德国有限公司 用于药物输送装置的剂量指示机构和药物输送装置
CN106999658A (zh) * 2014-11-24 2017-08-01 赛诺菲 用于可变剂量药物输送装置的药剂最大剂量设定机构
WO2016110561A1 (en) * 2015-01-08 2016-07-14 Novo Nordisk A/S Drug injection device with visual end-of-contents indicator system
WO2016193157A1 (en) * 2015-06-01 2016-12-08 Novo Nordisk A/S A housing for a medical injection device
JP6910355B2 (ja) * 2015-12-10 2021-07-28 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 取り外し可能に取り付け可能なセンサデバイスを備える薬物送達デバイス
US11318257B2 (en) 2016-12-01 2022-05-03 Novo Nordisk A/S Drug delivery device with clutch feature
EP3348298A1 (en) 2017-01-16 2018-07-18 Novo Nordisk A/S Drug delivery device with rotationally geared piston rod driver
US10688247B2 (en) 2017-07-13 2020-06-23 Haselmeier Ag Injection device with flexible dose selection
CN111315430A (zh) * 2017-11-07 2020-06-19 赛诺菲-安万特德国有限公司 带有预选器的注射装置
EP3706835A1 (en) * 2017-11-07 2020-09-16 Sanofi-Aventis Deutschland GmbH Injection device with a dose limiter
WO2019091878A1 (en) * 2017-11-07 2019-05-16 Sanofi-Aventis Deutschland Gmbh Injection device with a preselector
US11969583B2 (en) 2018-07-17 2024-04-30 Medmix Switzerland Ag Injection device with dose interruption fail safe
CN113613694B (zh) * 2019-02-19 2024-04-30 迈德米斯瑞士股份公司 具有用户友好的剂量选择器的注射装置
JP7713472B2 (ja) * 2020-05-11 2025-07-25 サノフイ 注射デバイス
CN119136864A (zh) * 2022-04-21 2024-12-13 赛诺菲 用于注射装置的驱动机构
CN115501426B (zh) * 2022-10-20 2025-11-28 江苏德尔福医疗器械有限公司 注射笔

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591136A (en) * 1991-04-15 1997-01-07 Medico Development Investment Company Injection device
WO2001072361A1 (en) * 2000-03-24 2001-10-04 Bernard Sams One-way clutch mechanisms and injector devices
WO2002030495A2 (en) * 2000-10-09 2002-04-18 Eli Lilly And Company Pen device for administration of parathyroid hormone
CN101035579A (zh) * 2004-10-04 2007-09-12 塞诺菲—安万特德国有限公司 用于药物输送装置的剂量显示机构

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH680904A5 (enExample) 1988-10-19 1992-12-15 Disetronic Ag
CN100506801C (zh) 2000-09-06 2009-07-01 诺华疫苗和诊断公司 糖元合成酶激酶3的抑制剂
US8875700B2 (en) * 2006-03-21 2014-11-04 Shl Group Ab Dose information device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591136A (en) * 1991-04-15 1997-01-07 Medico Development Investment Company Injection device
WO2001072361A1 (en) * 2000-03-24 2001-10-04 Bernard Sams One-way clutch mechanisms and injector devices
WO2002030495A2 (en) * 2000-10-09 2002-04-18 Eli Lilly And Company Pen device for administration of parathyroid hormone
CN101035579A (zh) * 2004-10-04 2007-09-12 塞诺菲—安万特德国有限公司 用于药物输送装置的剂量显示机构

Also Published As

Publication number Publication date
NO2401010T3 (enExample) 2018-09-15
US20110313365A1 (en) 2011-12-22
TR201807257T4 (tr) 2018-06-21
PL2401010T3 (pl) 2018-08-31
WO2010097125A1 (en) 2010-09-02
ES2672668T3 (es) 2018-06-15
CN102413854A (zh) 2012-04-11
DK2401010T3 (en) 2018-07-23
EP2401010B1 (en) 2018-04-18
AU2009341040B2 (en) 2013-01-10
US8372042B2 (en) 2013-02-12
AU2009341040A1 (en) 2011-09-29
EP2401010A1 (en) 2012-01-04

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Legal Events

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20190627

Address after: Swiss Swiss

Patentee after: Estral Medical Company

Address before: Swedish narka

Patentee before: SHL Medical AB

TR01 Transfer of patent right