CN102406658A - Paste plaster for treating psoriasis and preparation method thereof - Google Patents

Abstract

The invention discloses a paste plaster for treating psoriasis. The paste plaster comprises the following raw materials in parts by weight: 20-28 parts of white alum, 21-27 parts of mirabilite, 20-28 parts of sulphur, 4-7 parts of borneol, 200-300 parts of vaseline and 80-120 parts of paraffin. The paste plaster for treating psoriasis is prepared according to the following steps: a, weighting the raw materials in parts by weight; b, grinding white alum, mirabilite, sulphur and borneol into fine powder, and screening by a 100-meshed screen for later use; and c, putting the mixture obtained in the step b in a mortar for uniform stirring, adding vaseline to blend uniformly, and then adding liquid paraffin to regulate uniformly. The components are mutually matched to dispel disease mainly, and relieve wind heat, relieve dampness and turbidity, activate collaterals, harmonize qi and blood to realize metabolism, clarify skin, smooth blood vessel and remove stasis to promote tissue regeneration. The paste plaster plays effects mainly by using local skin administration, and has no adverse effect when in use. The paste plaster can take effect after being used once to twice by a patient with mild symptom generally, skin can gradually become soft and thin, the symptom can be relieved within 10-25 days and skin is gradually improved to be normal; and patients with long course of disease and serious symptoms can be recovered in 1-2 months usually.

Description

A kind of antipsoriatics cream and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine ointment, specifically, relate to a kind of antipsoriatics cream and preparation method thereof usefulness that is used for, belong to tcm field.

Background technology

The traditional Chinese medical science is thought: psoriasis is from the beginning of the heresy retardance skin that is mostly rheumatic fever, or the neck hyperhidrosis, due to the stiffened cloth friction etc., is that a kind of pathogenic factor smoulders in table, numbness plug skin network, the pathological manifestations that turbid blood is detained; The sick impairment of YIN of consumption for a long time liquid, nutrient QI and blood being insufficient, wind syndrome due to blood-deficiency is given birth to dry, and failure of skin and muscle to be nourished forms; Blood-deficiency leading to hyperactivity of the liver, feelings will is unsuccessful, gloomyly do not relax, or nervous tired, flaming up of heart-fire, so that QI-blood circulation dereliction of duty, the skin that stagnates whenever be prone to the key factor that becomes to bring out, and pathogenic feelings is shown effect repeatedly.

Modern medicine thinks that psoriasis is a neurodermatitis, is the chronic skin inflammation that turns to primary symptom with paroxysmal skin pruritus and skin lichen.Many with spirituality stimulations, physical property stimulation, sun exposure, scratch, wearing and tearing etc. are relevant, the clinical treatment method is a lot, but it is slow often to prove effective, and is regarded as one of department of dermatologry pertinacious disease, and is present, still do not have the efficacious therapy means.

Summary of the invention

The problem that invention will solve is to above deficiency, and good antipsoriatics cream of a kind of therapeutic effect and preparation method thereof is provided.

For solving above technical problem, the technical scheme that the present invention adopted is: a kind of antipsoriatics cream is characterized in that: said ointment is made up of the raw material of following weight portion:

Alumen 20-28 part, Natrii Sulfas 21-27 part, sulfur 20-28 part, Borneolum Syntheticum 4-7 part, vaseline 200-300 part and paraffin 80-120 part.

Further improvement as technique scheme:

Said ointment is made up of the raw material of following weight portion:

Alumen 22-26 part, Natrii Sulfas 23-25 part, sulfur 22-26 part, Borneolum Syntheticum 4-6 part, vaseline 230-270 part and paraffin 90-110 part.

Said ointment is made up of the raw material of following weight portion:

100 parts in 24 parts in Alumen, 24 parts in Natrii Sulfas, 24 parts in sulfur, 6 parts of Borneolum Syntheticums, 250 parts in vaseline and paraffin.

A kind of antipsoriatics cream, method for preparing may further comprise the steps:

A, get each raw material according to said weight portion;

B, Alumen, Natrii Sulfas, sulfur and Borneolum Syntheticum are ground into fine powder, cross 100 mesh sieves, subsequent use;

C, the mixture that step b is obtained place in the mortar and stir, and add vaseline and are in harmonious proportion evenly, add liquid paraffin again and regulate evenly, and psoriasic ointment obtains medical treatment.

In the above composition,

Alumen is claimed again: Alumen, Alumen, arcanite, potassium aluminium alum, potassium alum.Sour in the mouth, puckery, cold in nature, poisonous is gone into lung, liver, spleen, stomach, large intestine channel.Function: detoxifcation parasite killing, dampness removing to stop itchin, antidiarrheal, hemostasis, heat clearing away expectorant.Cure mainly; Epilepsy is gone mad, sore throat, accumulation and obstruction of sputum, hepatitis, jaundice, stomach, duodenal ulcer, uterine prolapse, leucorrhea, dysentery, aphtha of the mouth and tongue, eczema pruritus, skin ulcer hemorrhoid scabies etc.

Natrii Sulfas, another name sodium sulfate, nature and flavor with return through: salty, bitter, cold.Return the stomach warp; Lung meridian; Spleen channel; Kidney channel; Small intestine meridian; Tri-jiao channel; Large intestine channel.Function with cure mainly: purging heat to relax the bowels, moistening for dryness and softening hard mass, the detumescence of relieving inflammation or internal heat.Be used for the excess-heat constipation, constipation due to dry stool, stagnant stomachache, acute appendicitis swells and ache; The external treatment acute mastitis, swelling and pain of hemorrhoid.

Sulfur, acid, temperature; Poisonous.Go into kidney, large intestine channel.The external use anti pruritic parasite killing is treated skin ulcer; The fiery supporing yang relieving constipation of benefit for oral administration.External treatment is used for scabies, tinea alba, carbuncle of yin nature malignant boil; Take orally and be used for the sexual impotence cold foot, dyspnea due to deficiency cold asthma, deficiency and coldness constipation.

Borneolum Syntheticum, acrid in the mouth, hardship, cold nature.Go into the heart, lung meridian.The refreshment of having one's ideas straightened out, clearing heat for detumescence, analgesic function are arranged.Be used for coma, epidemic febrile disease unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm, lose consciousness, attacked by pestiferous factors, skin infection swell and ache, aphtha, laryngopharynx swelling and pain, conjunctival congestion and swelling pain, ophthalmic, gingival swelling and pain etc.

Vaseline is a kind of mineral wax, can form protecting film one in skin surface, very is fit to dry skin and uses.Can be used to be used as lip-stick, hand cream, wiping face or the body of rubbing one's body with a towel, is the extraordinary articles for use of preserving moisture.Nonirritant, stable not perishable, also be difficult for causing human body responsive.

Paraffin, bitter in the mouth, puckery, cool, heat clearing and inflammation relieving cure mainly otitis media, skin pruritus etc.Belong to medicinal additive, be used for curative cream base matter.

The present invention adopts above technical scheme; Compared with prior art, have the following advantages: various compositions cooperatively interact, and are main to get rid of illness; The wind heat, turbid, active, the smooth QI and blood of removing dampness of loosing with bar reach, skin Rong Run; Declare smooth blood vessels, promoting tissue regeneration by removing blood stasis mainly produces effects through the local skin administration, does not in use have any untoward reaction; The symptom difference, generally to use and take effect for 1-2 time, skin deliquescing gradually, attenuation can symptom be removed in 10-25 days, and skin is improved to normally gradually; Recovery from illness in the general 1-2 of the heavier person of course of disease skin skin month.

Below in conjunction with embodiment the present invention is described further.

The specific embodiment

Embodiment 1: a kind of antipsoriatics cream, form by the raw material of following weight portion: 80 parts in 20 parts in Alumen, 27 parts in Natrii Sulfas, 20 parts in sulfur, 7 parts of Borneolum Syntheticums, 300 parts in vaseline and paraffin.

Embodiment 2: a kind of antipsoriatics cream, form by the raw material of following weight portion: 120 parts in 28 parts in Alumen, 21 parts in Natrii Sulfas, 28 parts in sulfur, 4 parts of Borneolum Syntheticums, 200 parts in vaseline and paraffin.

Embodiment 3: a kind of antipsoriatics cream, form by the raw material of following weight portion:

90 parts in 22 parts in Alumen, 25 parts in Natrii Sulfas, 26 parts in sulfur, 4 parts of Borneolum Syntheticums, 230 parts in vaseline and paraffin.

Embodiment 4: a kind of antipsoriatics cream, form by the raw material of following weight portion:

110 parts in 26 parts in Alumen, 23 parts in Natrii Sulfas, 22 parts in sulfur, 6 parts of Borneolum Syntheticums, 270 parts in vaseline and paraffin.

Embodiment 5: a kind of antipsoriatics cream, form by the raw material of following weight portion:

100 parts in 24 parts in Alumen, 24 parts in Natrii Sulfas, 24 parts in sulfur, 6 parts of Borneolum Syntheticums, 250 parts in vaseline and paraffin.

The ointment of above embodiment prepares according to following steps respectively:

A, get each raw material according to said weight portion;

B, Alumen, Natrii Sulfas, sulfur and Borneolum Syntheticum are ground into fine powder, cross 100 mesh sieves, subsequent use;

C, the mixture that step b is obtained place in the mortar and stir, and add vaseline and are in harmonious proportion evenly, add liquid paraffin again and regulate evenly, and psoriasic ointment obtains medical treatment.

Above embodiment prepares the method for using of ointment: some chronic plump dermatoses such as psoriasis, neurodermatitis, chronic eczema, keratosis pilaris, knuckle pad, dip in ointment with cotton rod and be applied to the affected part, every day 1-2 time, the next day once, a week is a course of treatment.

The ointment of above embodiment preparation is used to treat psoriasic test, during year October in March, 2009-2011, chooses psoriatic 257 people and treat; Picked at random 40 example composition treatment groups 1,40 examples are formed treatment groups 2,40 routine treatment group 3,40 routine treatment groups 4,40 example composition treatment groups 5 and the 40 example composition matched groups formed of forming.

Treatment group 1 is used embodiment 1 gained ointment, and treatment group 2 is used embodiment 2 gained ointment, and treatment group 3 is used embodiment 3 gained ointment; Treatment group 4 is used embodiment 4 gained ointment; Treatment group 5 is used embodiment 5 gained ointment, dips in ointment with cotton rod and is applied to the affected part, every day 1-2 time; The next day once, a week is a course of treatment; Matched group is used Miconazole Nitrate Cream, i.e. daktarin external application, and every day 1 time, 7 days was 1 course of treatment.

Curative effect judging standard

Recovery from illness: symptom complete obiteration, skin lesion healing;

Produce effects: symptom is most of to disappear, and the skin lesion healing rate reaches more than 90%;

Invalid: symptom duration exists, and skin lesion changes not obvious.

Result such as following table that test obtains:

Can find out that from above data use ointment treatment psoriasis of the present invention, effect is apparent in view; Effective percentage reaches more than 90%, and therapeutic effect obviously is superior to matched group, treats after back 2 months and follows up a case by regular visits to; The treatment group does not have 1 example recurrence, and matched group recurs 8 examples and accounts for 16%, and the effect of embodiment 5 gained ointment is best.

Concrete case:

Poplar, the woman, 38 years old, cervical region both sides skin pruritus first quarter moon was surplus, intensive pimple occurred; The disgruntled sx of spirit, the surface scratching has vestige, and slight flushing is examined to psoriasis is coated with ointment every day 1-2 time; Symptom was clearly better on 2nd, used the first quarter moon transference cure, and color of the leather is normal, paid a return visit and did not have recurrence.

Zhang, the man, 40 years old, the workman, the plump skin lesion in back 2 years, pruritus is serious, and fatigue increases the weight of, and color is light white, and drying is examined and is psoriasis.Use ointment to be coated with outward, treat a week, sx was treated one month continuously, and symptom is eliminated recovery from illness, paid a return visit and did not have recurrence.

Zhao so-and-so, the man, 51 years old, suffered from psoriasis 10 years, serious pruritus, a large amount of desquamation are accompanied in erubescence, incrustation simultaneously, women's head-ornaments portion is many or the secondary infection squama is thicker greasy because of sebum. cooperate acupuncture, use ointment to be coated with outward, treatment recovery from illness in February does not have recurrence.

The king so-and-so, man, 48 years old.Made a definite diagnosis psoriasis 6 years.Find that the year before upper limb convexity property speckle pimple occurs with large stretch of squama.Head one yuan coin-size speckle.Lower limb are for increasing the speckle shape, and surperficial squama thickens, and the companion petechia comes off.Congestion and swelling pain occurs, idol has and feels run-down and the performance of ankylosis.Then go to local institute of traditional Chinese medicine to go to a doctor, be diagnosed as psoriasis, give intravenous drip, bad during the effect fashion, increase the weight of in the recent period, come me to go to a doctor and use ointment to be coated with outward, treat 1 first quarter moon recovery from illness, there is not recurrence.

Lee so-and-so, the woman, 45 years old, the patient was diagnosed as psoriasis, with heating, fear of cold, headache, discomfort such as weak, subcutaneous lymphadenectasis.Epidermis has squama, and small red dot appears in extremity, and begins to extend to other positions of health, with the moderate pruritus.White scales appears falling in epidermis, is diagnosed as psoriasis through local hospital, comes here to use ointment about 20 days, and recovery from illness is paid a return visit does not have recurrence.

Pueraria lobota so-and-so, the woman, 38 years old, come here to go to a doctor, patient shirtfront back, the point-like red pimple, pruritus is serious, and increases the weight of before coming with menstruation, comes here to use the moxibustion of ointment treatment gating, treats recovery from illness in 15 days.

Claims (4)

1. antipsoriatics cream, it is characterized in that: said ointment is made up of the raw material of following weight portion:

Alumen 20-28 part, Natrii Sulfas 21-27 part, sulfur 20-28 part, Borneolum Syntheticum 4-7 part, vaseline 200-300 part and paraffin 80-120 part.

2. a kind of antipsoriatics cream as claimed in claim 1, it is characterized in that: said ointment is made up of the raw material of following weight portion:

Alumen 22-26 part, Natrii Sulfas 23-25 part, sulfur 22-26 part, Borneolum Syntheticum 4-6 part, vaseline 230-270 part and paraffin 90-110 part.

3. a kind of antipsoriatics cream as claimed in claim 1, it is characterized in that: said ointment is made up of the raw material of following weight portion:

100 parts in 24 parts in Alumen, 24 parts in Natrii Sulfas, 24 parts in sulfur, 6 parts of Borneolum Syntheticums, 250 parts in vaseline and paraffin.

4. like claim 1,2 or 3 described a kind of antipsoriatics cream, it is characterized in that: said method for preparing may further comprise the steps:

A, get each raw material according to said weight portion;

B, Alumen, Natrii Sulfas, sulfur and Borneolum Syntheticum are ground into fine powder, cross 100 mesh sieves, subsequent use;

C, the mixture that step b is obtained place in the mortar and stir, and add vaseline and are in harmonious proportion evenly, add liquid paraffin again and regulate evenly, and psoriasic ointment obtains medical treatment.