CN102389538B - Traditional Chinese medicine capsule preparation for treating nasopharyngitis - Google Patents
Traditional Chinese medicine capsule preparation for treating nasopharyngitis Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine capsule preparation for treating nasopharyngitis, which is prepared by clinical test and repeated verification, and complies with theory of traditional Chinese medical science. The traditional Chinese medicine preparation is prepared by the following raw herbs: cocklebur fruit, asarum, cassia twig, coix seed, codonopsis pilosula, schizonepeta,platycodon grandiflorum, raspberry, smoked plum, mint, radix bupleuri, angelica root, houttuynia cordata, white atractylodes rhizome, radices sileris and liquorice. The traditional Chinese medicine capsule preparation has good treatment effect on clinical symptoms of rhinitis and pharyngitis, such as nasal obstruction, rhinorrhoea, sneezing, poor ventilation, cough, much phlegm, headache, dizziness, easy cold and the like, according to great and profound traditional theory of Chinese medical and medicine of China. The traditional Chinese medicine capsule preparation is convenient to prepare, quick-action after being taken, along with no toxic side effect and no adverse reaction after being taken.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, specifically a kind of Chinese medicinal capsule preparation for the treatment of rhinitis.
Background technology
Rhinitis is that the inflammatory disorders of nasal membrane mainly can be divided into acute rhinitis, chronic rhinitis, allergic rhinitis, rhinitis sicca, medicamentous rhinitis, chronic pharyngitis etc., its clinical symptoms mainly contains: nasal obstruction, watery nasal discharge, cough, abundant expectoration, sneeze, ventilate not smooth, headache, giddy, easy to catch cold etc.
Doctor trained in Western medicine mainly adopts antibiosis usually to carry out bactericidal antiphlogistic and treats, but medical expense is relatively high and the rear easily recurrence for the treatment of; The traditional Chinese medical science is lower but it need to adhere to multiplexing Chinese medicine for a long time with medical expense, has brought great inconvenience to people.
Summary of the invention
The purpose of this invention is to provide a kind of internal organs to human body not injury, medicining cycle is short especially with strengthening vital QI to eliminate pathogenic factors, lung qi dispersing is sensible, expelling wind and clearing away heat is main a kind of Chinese medicinal capsule preparation for the treatment of rhinitis and pharyngitis disease.
Medicine of the present invention is to use the traditional Chinese herbal medicine of China to be raw material, passes through the prescription of science, and formulated by repeatedly verifying of clinical trial, meets the theory of Chinese medicine.
The property of medicine of the selected Chinese herbal medicine of the present invention and function cure mainly and are respectively:
Herba Houttuyniae: suffering is slightly cold.Enter lung, kidney, urinary bladder channel.Relieving heat toxin, subduing inflammation, inducing diuresis for treating stranguria syndrome.Effect with heat clearing away, detoxifcation, dampness removing is used for lung abscess, phlegm-heat cough, leucorrhea, urinary tract infection, carbuncle furuncle etc.
The Rhizoma Atractylodis Macrocephalae: [meridian distribution of property and flavor] is bitter, sweet, temperature.Return spleen, stomach warp.[curing mainly function]: invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.Be used for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.Be used for insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, frequent fetal movement.
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature; Return bladder, liver, spleen channel.Function: expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.The diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus.
Radix Glycyrrhizae: sweet, flat.Enter 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate again the toxicity of all medicines, therefore for making medicine.
Fructus Xanthii: [meridian distribution of property and flavor] bitter in the mouth; Sweet; Hot; Warm in nature; Mild toxicity enters lung, Liver Channel.[function cures mainly] dispersing wind and cold; Clearing the nasal passage; Wind-damp dispelling; Antipruritic.Nasal sinusitis; Headche due to wind-cold; Rheumatic arthralgia; Rubella; Eczema; Scabies.
Herba Asari: nature and flavor are hot, warm, GUIXIN, lung meridian, and having dispels the heat dispels the wind, the effect of pain relieving, is used for the affection of exogenous wind-cold exterior syndrome;
Ramulus Cinnamomi: [meridian distribution of property and flavor] acrid in the mouth, sweet, temperature; GUIXIN, lung, urinary bladder channel.[function cures mainly :] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Be used for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Semen Coicis: [meridian distribution of property and flavor] is sweet; Light; Be slightly cold, [function cures mainly] spleen invigorating, eliminating dampness by diuresis, antidiarrheal, evacuation of pus.Be used for insufficiency of the spleen diarrhoea, muscle acid is heavy, arthralgia, and edema, beriberi, leucorrhea, lung abscess, it can promote the metabolism of body inner blood and moisture appendicitis, and promoting blood flow to regulate menstruation pain relieving, diuresis, anthydropic effect are arranged.
Radix Codonopsis: [meridian distribution of property and flavor] is sweet, and be flat.Return spleen, lung meridian.[curing mainly function]: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Herba Schizonepetae: [meridian distribution of property and flavor] suffering, tepor.Return lung, Liver Channel.Function cures mainly: the loose wind that induces sweat, rash, the skin ulcer that disappears, hemostasis.Radix Platycodonis: the flat tepor of [nature and flavor] property, hide hardship.Enter lung meridian.[function cures mainly] lung qi dispersing, sore-throat relieving eliminates the phlegm, evacuation of pus.
Fructus Rubi: [meridian distribution of property and flavor] sweet acid, flat.Enter liver, kidney two warps.[function cures mainly]: invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs makes eye bright.Control sexual impotence, seminal emission, frequency of micturition, incontinence of urine, asthenia, order is dark.
Fructus Mume: nature and flavor acid temperature, return liver, spleen, lung, large intestine channel, effect: astringe the lung, astringing intestine to stop diarrhea, the relieving colic caused by ascaris that promotes the production of body fluid, cure mainly: chronic cough is more than.
Herba Menthae: [meridian distribution of property and flavor] " suffering, cool, nontoxic." [function] aromatic drug, remedium corrigens and carminative.
Radix Bupleuri: bitter, be slightly cold, return liver, gallbladder meridian.Function cures mainly reconciling superficies and interior, soothing the liver, yang invigorating, is used for cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis, analgesic, calm, analgesia, antitussive, antibiotic, antiviral, antiinflammatory, Promote immunity function.
The Radix Angelicae Dahuricae: [meridian distribution of property and flavor] acrid in the mouth, temperature enter lung, spleen, stomach warp; Effect: control headache, supraorbital bone pain, toothache, cold-damp stomachache, skin pruritus, scabies.
A kind of Chinese medicinal capsule preparation for the treatment of rhinitis of the present invention is to be made by the crude drug of following weight proportion:
Fructus Xanthii 5-15 part, Herba Asari 5-10 part, Ramulus Cinnamomi 10-20 part, Semen Coicis 15-30 part,
Radix Codonopsis 10-20 part, Herba Schizonepetae 10-25 part, Radix Platycodonis 5-20 part, Fructus Rubi 5-10 part,
Fructus Mume 10-20 part, Herba Menthae 3-10 part, Radix Bupleuri 10-25 part, Radix Angelicae Dahuricae 5-15 part,
Herba Houttuyniae 5-15 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Saposhnikoviae 3-10 part, Radix Glycyrrhizae 10-20 part;
Preparation process is as follows:
(1) by formula proportion, Herba Houttuyniae, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Radix Glycyrrhizae, Fructus Xanthii, Herba Asari 6 flavor crude drug are ground into
100-300 order fine powder is standby;
(2) will remain Chinese herbal medicine according to formula proportion and put into marmite in the clear water immersion that adds 3 times of doses 2 hours, very hot oven boils, and then slow fire boiling is 30 minutes, and filter liquor is standby; Filtering residue is added 2 times of amount clear water again, decocted 20 minutes, filter waste, merge twice filtrate, heating is boiled into the thick paste shape, and it is standby that last ovendry power is broken to 100-300 order fine powder;
(3) with the fine powder mix homogeneously of step 1 and 2 preparations, incapsulate through cobalt-60 sterilization wrap and make the said capsule of pharmaceutics, every capsules explosive payload is 0.5 gram.
A kind of Chinese medicinal capsule preparation for the treatment of rhinitis of the present invention is to be made by the crude drug of following weight proportion:
Fructus Xanthii 8-12 part, Herba Asari 6-8 part, Ramulus Cinnamomi 12-18 part, Semen Coicis 20-25 part,
Radix Codonopsis 12-18 part, Herba Schizonepetae 15-20 part, Radix Platycodonis 8-15 part, Fructus Rubi 6-8 part,
Fructus Mume 12-18 part, Herba Menthae 5-8 part, Radix Bupleuri 15-20 part, Radix Angelicae Dahuricae 8-12 part,
Herba Houttuyniae 8-12 part, Rhizoma Atractylodis Macrocephalae 12-18 part, Radix Saposhnikoviae 5-8 part, Radix Glycyrrhizae 12-18 part.
A kind of Chinese medicinal capsule preparation for the treatment of rhinitis of the present invention is to be made by the crude drug of following weight proportion:
10 parts of Fructus Xanthii, 7 parts of Herba Asaris, 15 parts of Ramulus Cinnamomi, 22 parts of Semen Coiciss, 15 parts of Radix Codonopsis, 18 parts of Herba Schizonepetae, 12 parts of Radix Platycodoniss, 7 parts of Fructus Rubies, 15 parts of Fructus Mumes, 7 parts of Herba Menthaes, 18 parts of Radix Bupleuri, 10 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Houttuyniae, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of Radix Saposhnikoviaes, 15 parts, Radix Glycyrrhizae.
Excellent effect of the present invention is according to China's Chinese medicine traditional theory of extensive knowledge and profound scholarship, and selected 16 flavor Chinese herbal medicine use clinical proof, this Chinese medicine preparation is easy to prepare, take rear instant effect, have no side effect, have no adverse reaction after taking medicine, treatment every day three times, each 2-3 grain after meal, the sick time elder takes by three, and sick time short person take by two, one month is a course for the treatment of, the thing that the period in a medicine fasting is pungent and tobacco and wine and over-salty food.
Treatment is analyzed:
Cure result, by the preliminary clinical statistics to 300 patients, effective percentage is 97%, and cure rate is 76%, wherein, male 250 people, female's 50 examples, the oldest 79 years old, minimum 39 years old, average 56 years old, disease was had 10 years, short person half a year.Prove by the clinical treatment statistical data, the clinical symptoms picture nasal obstruction of this medicine to rhinitis and pharyngitis, watery nasal discharge, sneeze is ventilated not smooth, headache, cough, abundant expectoration, giddy, disease such as grade easy to catch cold has good therapeutic effect.
Clinical statistics signal table:
| ? | Case | Treatment cycle | Recovery from illness | Produce effects | Effectively | Invalid | Total effective rate |
| Embodiment 1 | 50 | 2 months | 10 | 30 | 6 | 4 | 92％ |
| Embodiment 2 | 50 | 1 month | 12 | 30 | 3 | 5 | 90％ |
| Embodiment 3 | 50 | 2 months | 30 | 9 | 7 | 4 | 92％ |
| Embodiment 4 | 50 | 2 months | 20 | 19 | 5 | 6 | 88％ |
| Embodiment 5 | 50 | 1 month | 20 | 6 | 9 | 3 | 94％ |
The specific embodiment
Embodiment 1
Fructus Xanthii 5g, Herba Asari 5g, Ramulus Cinnamomi 10g, Semen Coicis 15g, Radix Codonopsis 10g, Herba Schizonepetae 10g, Radix Platycodonis 5g, Fructus Rubi 5g, Fructus Mume 10g, Herba Menthae 3g, Radix Bupleuri 10g, Radix Angelicae Dahuricae 5g, Herba Houttuyniae 5g, Rhizoma Atractylodis Macrocephalae 10g, Radix Saposhnikoviae 3g, Radix Glycyrrhizae 10g.
Preparation process is as follows:
(1) by formula proportion, Herba Houttuyniae, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Radix Glycyrrhizae, Fructus Xanthii, Herba Asari 6 flavor crude drug are ground into 100-300 order fine powder standby;
(2) will remain Chinese herbal medicine according to formula proportion and put into marmite in the clear water immersion that adds 3 times of doses 2 hours, very hot oven boils, and then slow fire boiling is 30 minutes, and filter liquor is standby; Filtering residue is added 2 times of amount clear water again, decocted 20 minutes, filter waste, merge twice filtrate, heating is boiled into the thick paste shape, and it is standby that last ovendry power is broken to 100-300 order fine powder;
(3) with the fine powder mix homogeneously of step 1 and 2 preparations, incapsulate through cobalt-60 sterilization wrap and make the said capsule of pharmaceutics, every capsules explosive payload is 0.5 gram.
Embodiment 2
Fructus Xanthii 15g, Herba Asari 10g, Ramulus Cinnamomi 20g, Semen Coicis 30g, Radix Codonopsis 20g, Herba Schizonepetae 25g, Radix Platycodonis 20g, Fructus Rubi 10g, Fructus Mume 20g, Herba Menthae 10g, Radix Bupleuri 25g, Radix Angelicae Dahuricae 15g, Herba Houttuyniae 15g, Rhizoma Atractylodis Macrocephalae 20g, Radix Saposhnikoviae 10g, Radix Glycyrrhizae 20g.
Preparation process is identical with embodiment 1.
Embodiment 3
Fructus Xanthii 8g, Herba Asari 6g, Ramulus Cinnamomi 12g, Semen Coicis 20g, Radix Codonopsis 12g, Herba Schizonepetae 15g, Radix Platycodonis 8g, Fructus Rubi 6g, Fructus Mume 12g, Herba Menthae 5g, Radix Bupleuri 15g, Radix Angelicae Dahuricae 8g, Herba Houttuyniae 8g, Rhizoma Atractylodis Macrocephalae 12g, Radix Saposhnikoviae 5g, Radix Glycyrrhizae 12g.
Preparation method is identical with embodiment 1.
Embodiment 4
Fructus Xanthii 12g, Herba Asari 8g, Ramulus Cinnamomi 18g, Semen Coicis 25g, Radix Codonopsis 18g, Herba Schizonepetae 20g, Radix Platycodonis 15g, Fructus Rubi 8g, Fructus Mume 18g, Herba Menthae 8g, Radix Bupleuri 20g, Radix Angelicae Dahuricae 12g, Herba Houttuyniae 12g, Rhizoma Atractylodis Macrocephalae 18g, Radix Saposhnikoviae 8g, Radix Glycyrrhizae 18g.
Preparation method is identical with embodiment 1.
Embodiment 5
Fructus Xanthii 10g, Herba Asari 7g, Ramulus Cinnamomi 15g, Semen Coicis 22g, Radix Codonopsis 15g, Herba Schizonepetae 18g, Radix Platycodonis 12g, Fructus Rubi 7g, Fructus Mume 15g, Herba Menthae 7g, Radix Bupleuri 18g, Radix Angelicae Dahuricae 10g, Herba Houttuyniae 10g, Rhizoma Atractylodis Macrocephalae 15g, Radix Saposhnikoviae 6g, Radix Glycyrrhizae 15g.
Preparation method is identical with embodiment 1.
The typical clinical case
Case 1, the Qin *, the man, 25 years old, suffer from acute rhinitis, the many situations of nasal obstruction and secretions often occur, and mucus purulence nasal mucus appears in secretions.The congested swelling of its nasal mucosa on inspection has secretions.Take this medicine after 10 days, secretions disappears, smooth breathing.
Case 2, field * *, 17 years old, its symptom was nasal obstruction, and the lighter is intermittent or property alternately, and severe one is persistence, and nasal discharge increases.The congested swelling of nasal mucosa is seen in inspection, and nasal meatus has a small amount of mucus secretions, and serious hypertrophic rhinitis is due to hamartoplasia, and mucomembranous surface is uneven, and concha nasalis inferior is the Fructus Mori shape to be changed, and the middle nasal concha mucosa is Polypoid changes.After taking for 2 weeks, above-mentioned symptom is eliminated substantially, breathes smooth and easy.
Case 3, king * *, 45 years old, suffer from allergic rhinitis, nasal membrane is extremely sensitive to some composition in air amount, internal energy morbidity on the one repeatedly, during morbidity, health is extremely uncomfortable.Use this medicine after 15 days, the number of times of falling ill every day reduces, after the week, and transference cure.
Case 4, *, 52 years old, certain Enterprise Staff, due to the work cause, the long-term irriate of nasal mucosa and the atrophy of mucus body of gland, secretions occur reduce, mucosa is dry.Use this medicine after 15 days, transference cure, nasal membrane are no longer dry.
Case 5, Lee *, 35 years old, suffer from the seasonal rhinitis, nose is relatively poor to this climate change adaptive capacity that colds and heat succeed each other too fast, in the situation that also do not adapt to cold air, state of an illness outbreak; Use this medicine after one week, transference cure continues to take medicine a course for the treatment of in order to consolidate curative effect.
Case 6, Korea Spro * *, 30 years old, suffer from the rhinitis initial stage, use incorrect nasal cavity medicine, and anxious because of its treatment, use amount is excessive, with induced damage resistive the structure of nasal mucosa cilium, affected the physiological function of nasal mucosa.Use this medicine to be almost recovered after 2 weeks, continual cure recovery from illness after one week.
Case 7, the Meng *, 12 years old, the nasal obstruction, stuffiness, nasal cavity secretions is more.After taking 15, secretions disappears, and breathes unimpeded.
Case 8, Liu * *, 10 years old, nasal obstruction, watery nasal discharge is regularly felt dizzy, headache; After taking 14, aforementioned transference cure.
Claims (3)
1. Chinese medicinal capsule preparation for the treatment of rhinitis it is characterized in that being made by the crude drug of following weight proportion:
Fructus Xanthii 5-15 part, Herba Asari 5-10 part, Ramulus Cinnamomi 10-20 part, Semen Coicis 15-30 part,
Radix Codonopsis 10-20 part, Herba Schizonepetae 10-25 part, Radix Platycodonis 5-20 part, Fructus Rubi 5-10 part,
Fructus Mume 10-20 part, Herba Menthae 3-10 part, Radix Bupleuri 10-25 part, Radix Angelicae Dahuricae 5-15 part,
Herba Houttuyniae 5-15 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Saposhnikoviae 3-10 part, Radix Glycyrrhizae 10-20 part;
Preparation process is as follows:
(1) by formula proportion, Herba Houttuyniae, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Radix Glycyrrhizae, Fructus Xanthii, Herba Asari 6 flavor crude drug are ground into 100-300 order fine powder standby;
(2) will remain Chinese herbal medicine according to formula proportion and put into marmite in the clear water immersion that adds 3 times of doses 2 hours, very hot oven boils, and then slow fire boiling is 30 minutes, and filter liquor is standby; Filtering residue is added 2 times of amount clear water again, decocted 20 minutes, filter waste, merge twice filtrate, heating is boiled into the thick paste shape, and it is standby that last ovendry power is broken to 100-300 order fine powder;
(3) with the fine powder mix homogeneously of step (1) and (2) preparation, incapsulate through cobalt-60 sterilization wrap and get product.
2. a kind of Chinese medicinal capsule preparation for the treatment of rhinitis according to claim 1 is characterized in that being made by the crude drug of following weight proportion:
Fructus Xanthii 8-12 part, Herba Asari 6-8 part, Ramulus Cinnamomi 12-18 part, Semen Coicis 20-25 part,
Radix Codonopsis 12-18 part, Herba Schizonepetae 15-20 part, Radix Platycodonis 8-15 part, Fructus Rubi 6-8 part,
Fructus Mume 12-18 part, Herba Menthae 5-8 part, Radix Bupleuri 15-20 part, Radix Angelicae Dahuricae 8-12 part,
Herba Houttuyniae 8-12 part, Rhizoma Atractylodis Macrocephalae 12-18 part, Radix Saposhnikoviae 5-8 part, Radix Glycyrrhizae 12-18 part.
3. a kind of Chinese medicinal capsule preparation for the treatment of rhinitis according to claim 2 is characterized in that being made by the crude drug of following weight proportion:
10 parts of Fructus Xanthii, 7 parts of Herba Asaris, 15 parts of Ramulus Cinnamomi, 22 parts of Semen Coiciss, 15 parts of Radix Codonopsis, 18 parts of Herba Schizonepetae, 12 parts of Radix Platycodoniss, 7 parts of Fructus Rubies, 15 parts of Fructus Mumes, 7 parts of Herba Menthaes, 18 parts of Radix Bupleuri, 10 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Houttuyniae, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts of Radix Saposhnikoviaes, 15 parts, Radix Glycyrrhizae.
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| CN1043629A (en) * | 1988-12-27 | 1990-07-11 | 陈世和 | The production method of rhinitis medicine |
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| CN1043629A (en) * | 1988-12-27 | 1990-07-11 | 陈世和 | The production method of rhinitis medicine |
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