CN102370731A - Medicament for treating prolapse of lumbar intervertebral disc, hyperosteogeny and hydrarthrosis and preparation method thereof - Google Patents

Medicament for treating prolapse of lumbar intervertebral disc, hyperosteogeny and hydrarthrosis and preparation method thereof Download PDF

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Publication number
CN102370731A
CN102370731A CN2011103310398A CN201110331039A CN102370731A CN 102370731 A CN102370731 A CN 102370731A CN 2011103310398 A CN2011103310398 A CN 2011103310398A CN 201110331039 A CN201110331039 A CN 201110331039A CN 102370731 A CN102370731 A CN 102370731A
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hyperosteogeny
intervertebral disc
parts
lumbar intervertebral
medicine
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CN102370731B (en
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姜永兰
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Jiang Yonglan
NIU GAOFENG
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NIU GAOFENG
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Abstract

The invention discloses a medicament for treating prolapse of lumbar intervertebral disc, hyperosteogeny and hydrarthrosis and a preparation method thereof. The medicament is prepared from the following raw materials in parts by weight: 10-25 parts of scorpion, 7-25 parts of leech, 5-18 parts of little multibanded krait, 7-24 parts of Chinese polyphaga, 10-28 parts of Cosymbotus platyurus, 30-55 parts of garden balsam stem, 30-55 parts of hemlock parsley, 30-55 parts of kusnezoff monkshood and 30-55 parts of radix achyranthis bidentatae. The preparation method of the medicament comprises the following steps: (1) weighing the active pharmaceutical ingredients according to the parts by weight; (2) baking the active pharmaceutical ingredients, crushing into powder, and thoroughly mixing; and (3) quickly placing the mixture obtained in the step (2) into a sealing bag. The medicament disclosed by the invention is mainly applicable to prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrosis, cervical spondylosis and lumbar spinal stenosis, and has good treatment effects on rheumatism and rheumatoid arthritis.

Description

A kind of treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine and preparation method thereof, relate in particular to a kind of treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine and preparation method thereof.
Background technology
Diseases such as prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrosis are a frequently-occurring disease, commonly encountered diseases, and by endogenous cause of ill and many exopathogenic factors of the pathological changes that self wears out, for example external force damage, faulty posture cause.This type disease is pathological changes at the skeleton place, the treatment difficulty, and the medicine on the market is a lot, and the medication cycle is long, and the pain in the time of can only alleviating morbidity usually can not be eliminated focus.
Summary of the invention
Problem to be solved by this invention provides a kind of treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine and preparation method thereof, can effectively treat prolapse of lumbar intervertebral disc, all kinds of hyperosteogeny, hydrarthrosis, and treatment time is short, and healing effect is good.
Problem to be solved by this invention realizes through following technical scheme:
A kind of treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine are formed by following weight portion feedstock production: Scorpio 10-25, Hirudo 7-25, Serpentis 5-18, eupolyphoge sinensis 7-24, gecko 10-28, Herba speranskiae tuberculatae 30-55, Rhizoma Chuanxiong 30-55, Radix Aconiti Kusnezoffii 30-55, Radix Achyranthis Bidentatae 30-55.
Described treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine are formed by following weight portion feedstock production: Scorpio 13-22, Hirudo 10-20, Serpentis 8-15, eupolyphoge sinensis 10-20, gecko 13-23, Herba speranskiae tuberculatae 35-45, Rhizoma Chuanxiong 35-45, Radix Aconiti Kusnezoffii 35-45, Radix Achyranthis Bidentatae 35-45.
Described treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine are formed by following weight portion feedstock production: Scorpio 18, Hirudo 15, Serpentis 12, eupolyphoge sinensis 15, gecko 18, Herba speranskiae tuberculatae 42, Rhizoma Chuanxiong 42, Radix Aconiti Kusnezoffii 42, Radix Achyranthis Bidentatae 42.
Said medicine is prepared into powder.
The method for preparing of above-mentioned treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine may further comprise the steps:
(1) takes by weighing each raw medicinal material by above-mentioned weight portion;
(2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix;
(3) mixture in the step (2) is placed sealing bag fast.
Said step (2) Chinese crude drug is crushed to the 100-200 order.
Said medication preparation becomes powder.
The powder that said medication preparation becomes places on the plaster cloth, processes patch.
The effect of said various medical materials is selected for use as follows:
Serpentis: another name Agkistrodon, Serpentis, Flos Chrysanthemi Serpentis; Nature and flavor are sweet, salty, warm; Return liver, kidney channel; Has the wind of searching dehumidifying, dredge the meridian passage, the effect of pain relieving arresting convulsion.
Scorpio: property is hot, flat, poisonous, returns Liver Channel; Effect with endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.
Hirudo: the salty hardship of property, flat, slightly poisonous, be included into Liver Channel; The effect of have removing blood stasis, removing blood stasis, stimulating the menstrual flow.
Eupolyphoge sinensis: also claim Eupolyphaga Seu Steleophaga, Eupolyphaga Seu Steleophaga, eupolyphaga, nature and flavor are salty, cold, slightly poisonous; Return Liver Channel; Has removing blood stasis with potent drugs blood, the effect of reuniting the fractured tendons and bones.
Gecko is also claimed Gekko Swinhonis, Gekko Swinhonis, and property is salty, cold, slightly poisonous; Have and dispel the wind, active, the effect of eliminating stagnation.
Radix Aconiti Kusnezoffii: acrid in the mouth, hardship, heat, very toxic; GUIXIN, liver,kidney,spleen warp; Expelling wind and removing dampness is arranged, the effect of antalgic.
Radix Achyranthis Bidentatae: nature and flavor are bitter, acid, flat, go into the Liver and kidney warp; Effect with invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.
Herba speranskiae tuberculatae: be the herb of euphorbia plant speranskia tuberculata, nature and flavor are bitter, hot, temperature; Be included into lung, liver two warps; Has expelling wind and removing dampness, detoxifcation analgesic effect.
Rhizoma Chuanxiong: the hot temperature of property, go into liver, gallbladder, pericardium channel; Effect with blood-activating and qi-promoting, wind-expelling pain-stopping.
The monarch compatibility and the synergism of medicine of the present invention are following:
This formula and prescription is rigorous; Take into full account the reasonably combined of monarch medicine; Can bring into play active, the eliminating stagnation effect of monarch drug Scorpio, Hirudo, Serpentis, eupolyphoge sinensis and gecko, strengthen promoting the circulation of blood, bone and muscle strengthening effect with the ministerial drug Radix Achyranthis Bidentatae again, make the monarch drug property of medicine with cure mainly function and strengthen; Again with the expelling wind and removing dampness of adjuvant drug Radix Aconiti Kusnezoffii, Herba speranskiae tuberculatae and messenger drug Rhizoma Chuanxiong, the important effect that the analgesic effect increases this prescription.
Drug main of the present invention will be applicable under prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrosis, cervical spondylosis, the lumbar vertebra pipe narrow, and rheumatism and rheumatoid are also had better curative effect.
For proving above-mentioned advantage, medicine of the present invention has carried out the clinical verification with the patch among the embodiment 1, and curative effect is apparent in view.
Clinical trial result is analyzed:
This test portion adopts single center, parallel, open trial, goes into to organize narrow patient's 1546 examples under prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrosis, cervical spondylosis, the lumbar vertebra pipe altogether, accomplishes 1546 examples, and 0 example that comes off is rejected 0 example; There are 1546 routine patients to try out patch and carried out efficiency evaluation; Prolapse of lumbar intervertebral disc 380 examples wherein, male's 210 examples, women's 170 examples; Hyperosteogeny 392 examples, male's 152 examples, women's 240 examples; Hydrarthrosis 290 examples, male's 170 examples, women's 120 examples, cervical spondylosis 310 examples, male's 127 examples, women's 183 examples, narrow 174 examples under the lumbar vertebra pipe, male's 74 examples, women's 100 examples.
Clinical symptoms and sign: prolapse of lumbar intervertebral disc 380 routine patients mainly show as flank pain; Its pain scope mainly is at waist and lumbosacral region, and is the most common with persistent dull pain, and pain can alleviate during horizontal position; When erect position and seat, this pain can increase the weight of; Hyperosteogeny 392 routine patients mainly show as pain, swelling, limbs disturbance; The swelling of the main performance of hydrarthrosis 290 example arthremia, pain is oozed out and is increased, hydrarthrosis, the activity difficulty of squatting down, function limitation; Cervical spondylosis 310 examples mainly show vertebra joint unstability, loosening, and vertebral pulp is outstanding or deviate from bony spur formation, the spinal canal stenosis of ligament plumpness and secondary etc.; Narrow patient's 174 examples show as the compressing cauda equina nerve under the lumbar vertebra pipe, numbness, the twinge of perineal position occur, urinate, defecation inability.
Usage and dosage: during treatment patch is applied in the affected part, the next day, change dressings 1 time, and one month is a course of treatment.
Therapeutic outcome: prolapse of lumbar intervertebral disc 380 routine patient treatment 2-3 all took an evident turn for the better after the course of treatment, and are without any side effects, treat 4-5 course cure rate more than 98%.Hyperosteogeny 392 routine patient treatment 2-3 all took an evident turn for the better after the course of treatment, and are without any side effects, treat 4-5 course cure rate more than 98%.Hydrarthrosis 290 routine patient treatment 2-3 all took an evident turn for the better after the course of treatment, and are without any side effects, treat 4-5 course cure rate more than 97%.Cervical spondylosis 310 routine patient treatment 2-3 all took an evident turn for the better after the course of treatment, and are without any side effects, treat 4-5 course cure rate more than 98%.Narrow patient 174 routine patient treatment 2-3 all took an evident turn for the better after the course of treatment under the lumbar vertebra pipe, and are without any side effects, treat 4-5 course cure rate more than 96%.
This medicine also has curative effect preferably to rheumatism and rheumatoid, all takes an evident turn for the better after treating 3 courses of treatment, and is without any side effects, treats 5-6 course cure rate more than 80%.
The pharmacology of medicine of the present invention proves; Said medicine effectively infiltrates through the skeleton place in affected part; To phenomenons such as surrounding tissue edema, fibrin deposition, a large amount of inflammatory cell infiltration, MCP, macrophage inflammatory proteins; Carry out effective inhibition, had the effect of antiinflammatory and analgesic.
Therapeutic outcome shows that this medical instrument has channels sootheing and network vessel quickening, blood circulation and promoting silt, the effect of reducing swelling and alleviating pain; Has a splendid curative effect to narrow under prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrosis, cervical spondylosis, the lumbar vertebra pipe.
The specific embodiment
Embodiment 1
A kind of treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine are formed by following weight portion (kg) feedstock production: Scorpio 18, Hirudo 15, Serpentis 12, eupolyphoge sinensis 15, gecko 18, Herba speranskiae tuberculatae 42, Rhizoma Chuanxiong 42, Radix Aconiti Kusnezoffii 42, Radix Achyranthis Bidentatae 42.
The method for preparing of above-mentioned treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine may further comprise the steps:
(1) takes by weighing each raw medicinal material by above-mentioned weight portion;
(2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix;
(3) mixture in the step (2) is crushed to 200 orders, is prepared as patch.
Embodiment 2
A kind of treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine are formed by following weight portion (kg) feedstock production: Scorpio 13, Hirudo 10, Serpentis 8, eupolyphoge sinensis 10, gecko 13, Herba speranskiae tuberculatae 35, Rhizoma Chuanxiong 35, Radix Aconiti Kusnezoffii 35, Radix Achyranthis Bidentatae 35.
The method for preparing of above-mentioned treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine may further comprise the steps:
(1) takes by weighing each raw medicinal material by above-mentioned weight portion;
(2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix;
(3) mixture in the step (2) is crushed to 200 orders, is prepared as patch.
Embodiment 3
A kind of treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine are formed by following weight portion (kg) feedstock production: Scorpio 22, Hirudo 20, Serpentis 15, eupolyphoge sinensis 20, gecko 23, Herba speranskiae tuberculatae 45, Rhizoma Chuanxiong 45, Radix Aconiti Kusnezoffii 45, Radix Achyranthis Bidentatae 45.
The method for preparing of above-mentioned treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine may further comprise the steps:
(1) takes by weighing each raw medicinal material by above-mentioned weight portion;
(2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix;
(3) mixture in the step (2) is crushed to 120 orders, is prepared as powder.
Embodiment 4
A kind of treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine are formed by following weight portion (kg) feedstock production: Scorpio 10, Hirudo 7, Serpentis 5, eupolyphoge sinensis 7, gecko 10, Herba speranskiae tuberculatae 30, Rhizoma Chuanxiong 30, Radix Aconiti Kusnezoffii 30, Radix Achyranthis Bidentatae 30.
The method for preparing of above-mentioned treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine may further comprise the steps:
(1) takes by weighing each raw medicinal material by above-mentioned weight portion;
(2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix;
(3) mixture in the step (2) is crushed to 180 orders, is prepared as patch.
Embodiment 5
A kind of treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine are formed by following weight portion (kg) feedstock production: Scorpio 25, Hirudo 25, Serpentis 18, eupolyphoge sinensis 24, gecko 28, Herba speranskiae tuberculatae 55, Rhizoma Chuanxiong 55, Radix Aconiti Kusnezoffii 55, Radix Achyranthis Bidentatae 55.
The method for preparing of above-mentioned treatment prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine may further comprise the steps:
(1) takes by weighing each raw medicinal material by above-mentioned weight portion;
(2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix;
(3) mixture in the step (2) is crushed to 200 orders, is prepared as patch.

Claims (8)

1. treat prolapse of lumbar intervertebral disc, hyperosteogeny, hydrarthrodial medicine for one kind, form by following weight portion feedstock production: Scorpio 10-25, Hirudo 7-25, Serpentis 5-18, eupolyphoge sinensis 7-24, gecko 10-28, Herba speranskiae tuberculatae 30-55, Rhizoma Chuanxiong 30-55, Radix Aconiti Kusnezoffii 30-55, Radix Achyranthis Bidentatae 30-55.
2. treatment prolapse of lumbar intervertebral disc according to claim 1, hyperosteogeny, hydrarthrodial medicine are formed by following weight portion feedstock production: Scorpio 13-22, Hirudo 10-20, Serpentis 8-15, eupolyphoge sinensis 10-20, gecko 13-23, Herba speranskiae tuberculatae 35-45, Rhizoma Chuanxiong 35-45, Radix Aconiti Kusnezoffii 35-45, Radix Achyranthis Bidentatae 35-45.
3. treatment prolapse of lumbar intervertebral disc according to claim 1, hyperosteogeny, hydrarthrodial medicine are formed by following weight portion feedstock production: Scorpio 18, Hirudo 15, Serpentis 12, eupolyphoge sinensis 15, gecko 18, Herba speranskiae tuberculatae 42, Rhizoma Chuanxiong 42, Radix Aconiti Kusnezoffii 42, Radix Achyranthis Bidentatae 42.
4. according to the described treatment prolapse of lumbar intervertebral disc of one of claim 1-3, hyperosteogeny, hydrarthrodial medicine, said medication preparation becomes powder or patch.
5. according to the method for preparing of the described treatment prolapse of lumbar intervertebral disc of one of claim 1-3, hyperosteogeny, hydrarthrodial medicine, may further comprise the steps:
(1) takes by weighing each raw medicinal material by the weight portion among one of claim 1-3;
(2) above-mentioned each raw medicinal material is dried, is ground into powder, fully mix;
(3) mixture in the step (2) is placed sealing bag fast.
6. the method for preparing of treatment prolapse of lumbar intervertebral disc according to claim 5, hyperosteogeny, hydrarthrodial medicine, said step (2) Chinese crude drug is crushed to the 100-200 order.
7. the method for preparing of treatment prolapse of lumbar intervertebral disc according to claim 5, hyperosteogeny, hydrarthrodial medicine, said medication preparation becomes powder.
8. the method for preparing of treatment prolapse of lumbar intervertebral disc according to claim 7, hyperosteogeny, hydrarthrodial medicine, the powder that said medication preparation becomes places on the plaster cloth, processes patch.
CN201110331039.8A 2011-10-27 2011-10-27 Medicament for treating prolapse of lumbar intervertebral disc, hyperosteogeny and hydrarthrosis and preparation method thereof Active CN102370731B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103565896A (en) * 2013-11-25 2014-02-12 宋文学 Elaphe moellendorffi-contained medicated wine
CN104257961A (en) * 2014-10-17 2015-01-07 罗伟汉 Dressing for treating neck shoulder waist and leg pain, slipped disc and rheumatoid hyperplasia and preparation method of dressing
CN107412491A (en) * 2017-08-24 2017-12-01 石玉芹 A kind of externally applied ointment for treating hyperosteogeny patch and preparation method thereof
CN110051767A (en) * 2019-05-08 2019-07-26 汤合燕 A kind of external medicinal liquid and preparation method thereof with blood circulation invigorating efficacies

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CN101502615A (en) * 2009-02-10 2009-08-12 温志民 Plaster for traumatic injury and bone fracture

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CN1640440A (en) * 2004-01-12 2005-07-20 张金学 External-use Chinese medicine for treating osteoproliferation and its preparing method
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103565896A (en) * 2013-11-25 2014-02-12 宋文学 Elaphe moellendorffi-contained medicated wine
CN104257961A (en) * 2014-10-17 2015-01-07 罗伟汉 Dressing for treating neck shoulder waist and leg pain, slipped disc and rheumatoid hyperplasia and preparation method of dressing
CN107412491A (en) * 2017-08-24 2017-12-01 石玉芹 A kind of externally applied ointment for treating hyperosteogeny patch and preparation method thereof
CN110051767A (en) * 2019-05-08 2019-07-26 汤合燕 A kind of external medicinal liquid and preparation method thereof with blood circulation invigorating efficacies

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