CN102370162B - Health-care food for relieving physical fatigue prepared by taking termite as main raw material - Google Patents
Health-care food for relieving physical fatigue prepared by taking termite as main raw material Download PDFInfo
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- CN102370162B CN102370162B CN2010102478698A CN201010247869A CN102370162B CN 102370162 B CN102370162 B CN 102370162B CN 2010102478698 A CN2010102478698 A CN 2010102478698A CN 201010247869 A CN201010247869 A CN 201010247869A CN 102370162 B CN102370162 B CN 102370162B
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Abstract
The invention provides a health-care food for relieving physical fatigue prepared by taking termite as a main raw material. The health-care food is prepared from termite extract and extract of astragalus mongholicus, epimedium herb, medlar and cinnamon. The health-care food does not have toxic or side effect and is safe to be taken for a long time; and criterion in Standard of Health Food Test and Assessment (2003 edition) shows that the health-care food has the function of relieving the physical fatigue for animals and human bodies. The health-care food is suitable to be taken by fatigue crowd.
Description
Technical field
The present invention relates to utilize health food that termite and food and medicine consangunity Chinese medicine make and preparation method thereof.
Background technology
Termite claims Wei, claims again Bai Xuanju, is one of seven large miracles of Contemporary Biology, is the venerable old man or lady in the animal on the world land, is again the king of anti-anoxic, and it contains rich in protein, various vitamin and trace element; Contained cursive script formaldehyde is mended power not second to ginseng; Contained atriphos and related substances are the important sources that produces strength.The edible medicinal of termite is worth just on the books in Compendium of Material Medica.In traditional medicine, be only limited to and termite is fried the oven dry pulverize or steep in wine and take.Because edible, medicinal termite powder amount is larger, this meal preparation side effect and heavier to gastrointestinal side effect makes the people be difficult to adhere to taking.
Summary of the invention
Purpose of the present invention is exactly to utilize the special efficacy of termite, and auxiliary and other food and medicine consangunity Chinese medicines provide a kind of health food and preparation method of energy alleviating physical fatigue again.
Health food of the present invention is capsule, and is formulated by following material (consumption is weight portion): termite extract 35-60, the Radix Astragali, barrenwort, the fruit of Chinese wolfberry, cinnamomum cassia extract 38-72
The preferential proportioning of the used material of the present invention (consumption is weight portion) is as follows:
Termite extract 40-55, the Radix Astragali, barrenwort, the fruit of Chinese wolfberry, cinnamomum cassia extract 45-65.
The best proportioning of the used material of the present invention (consumption is weight portion) is as follows:
Termite extract 48, the Radix Astragali, barrenwort, the fruit of Chinese wolfberry, cinnamomum cassia extract 52.
The described Radix Astragali, barrenwort, the fruit of Chinese wolfberry and Chinese cassia tree consumption weight ratio are 3: 3: 2: 2, and described termite extract is that the employing enzymatic isolation method filters and gets, the pH value of enzymolysis liquid is 6.8-7.3 during enzymolysis.The described Radix Astragali, barrenwort, matrimony vine, cinnamomum cassia extract are to adopt the hot reflux extraction to filter and get.Its temperature is controlled at 80-130 ℃, and the time is 150-210 minute.
Preparation technology of the present invention is as follows:
1, termite extract and the Radix Astragali, barrenwort, the fruit of Chinese wolfberry, cinnamomum cassia extract are mixed, get mixed liquor.After more above-mentioned mixed liquor being concentrated to relative density and being 1.08-1.10 (60 ℃ of surveys), add 95% edible alcohol that volume equates, stir, make pure content reach 46-68%, left standstill 24 hours, get supernatant, filter, behind the filtrate decompression recovered alcohol, place for subsequent use.
2, precipitation solution is concentrated, being concentrated into relative density is 1.08-1.10 (60 ℃ of surveys), gets clearly cream.
3, above-mentioned clear cream is carried out spray-drying, get dry powder.
4, the dry powder with gained places fluidized granulation mechanism grain, whole grain, gets dried particle.
5, dried particle is filled at the automatic capsule filling machine, the loading amount specification is 0.45g/ grain or 0.25g/ grain.
Animal experiment has proved that health food of the present invention belongs to non-poisonous material, and the result is all negative for three genetic toxicity tests (Salmonella reversion test, PCEMNR micronucleus test, mouse sperm deformity test).Feeding trial had no side effect to rat in 30 days, long-term taking safety.Functional trial proved swimming with a load attached to the body time that health food of the present invention can the significant prolongation mouse, significantly reduce tired mice serum urea produces, significantly increases the hepatic glycogen storage level.And the body weight gain of mouse and exercised rats blood lactic acid increased and eliminate, have no significant effect.Point out health food of the present invention that animal and human's body is had the alleviating physical fatigue function according to criterion in " health food check and assessment technique standard " (version in 2003).Being suitable for tired crowd takes.
Embodiment 1
Get wild or the termite propagated artificially after drying, be crushed into powder with pulverizer, the gained powder is placed in the enzymatic vessel, by the immersion that discharges water of 1: 8 weight ratio, then add active papain and carry out enzymolysis, enzymolysis time 5 hours, noting adjusting pH value during enzymolysis is 6.8-7.0; Put into the hot reflux extractor after the Radix Astragali, barrenwort, matrimony vine, the Chinese cassia tree coarse crushing, adding water by 1: 10 weight ratio carries out water extraction and gets, the water extraction secondary, it is 2 hours for the first time, be 1.5 hours for the second time, temperature is controlled at 100 ℃, and above-mentioned two kinds of extracts are filtered respectively, merging concentrates → sprays → granulates → fill after filtering, and gets health food of the present invention.
Embodiment 2
The preparation method is with embodiment 1, and just the pH value of enzymolysis liquid is 8, and hot reflux is extracted Chinese medicine for once, and the time is 150 minutes, and temperature is controlled at 130 ℃.
Embodiment 3
The preparation method is with embodiment 1, the pH value 7.5 of enzymolysis liquid just, and hot reflux is extracted Chinese medicine for once, and the time is 210 minutes, and temperature is controlled at 120 ℃.
According to the detection of disease prevention and control center, Hunan Province detection to sample of the present invention, health food of the present invention belongs to non-poisonous material, and long-term taking safety contains total saponin(e＞700mg among the every 100g of content, icariin＞40mg, significantly relieving fatigue.
The related experiment data are as follows:
1, health food of the present invention is on the impact (seeing Table 1) of mice burden swimming time
Table 1 the present invention is on the impact of mice burden swimming time (χ ± SD)
| Group | Dosage (g/kg.bw) | Number of animals (only) | Swimming time (s) | The P value |
| Control group | 0.00 | 10 | 524±430 | --- |
| Low dose group | 0.45 | 10 | 562±434 | 0.996 |
| Middle dosage group | 0.90 | 10 | 680±448 | 0.827 |
| High dose group | 2.70 | 10 | 1204±662 | 0.012 |
2, the present invention is on the impact (seeing Table 2) of tired mice serum and urea
Table 2 the present invention is on the impact of tired mice serum and urea (χ ± SD)
| Group | Dosage (g/kg.bw) | Number of animals (only) | Urea (mmo l/L) | The P value |
| Control group | 0.00 | 10 | 9.90±1.75 | --- |
| Low dose group | 0.45 | 10 | 8.13±1.76 | 0.405 |
| Middle dosage group | 0.90 | 10 | 7.53±1.60 | 0.091 |
| High dose group | 2.70 | 10 | 6.53±1.23 | 0.003 |
3, the present invention is on the impact (seeing Table 3) of exercised rats blood lactic acid TG-AUC
Table 3 the present invention is on the impact of exercised rats blood lactic acid TG-AUC (χ ± SD)
4, the present invention is on the impact (meeting 4) of Mouse Liver glycogen storage level
Table 4 the present invention is on the impact of Mouse Liver glycogen storage level (χ ± SD)
The experiment brief summary
The per os gavage gives the health food of the present invention 30 days of mouse 0.45g/kg.bw, 0.90g/kg.bw, 2.70g/kg.bw dosage, compare with control group, 2.70g/kg.bw dosage can significant prolongation mouse the swimming with a load attached to the body time, significantly reduce tired mice serum urea and produce, significantly increase the hepatic glycogen storage level.Exercised rats blood lactic acid is increased each dosage and elimination has no significant effect.
According to criterion in " health food check and assessment technique standard " (2003 editions), confirm that the present invention has the alleviating physical fatigue function to motion and human body.
Claims (4)
1. the health food of an alleviating physical fatigue of making take termite as primary raw material, it is characterized in that by following consumption being that the material of weight portion is formulated: termite extract 35-60, the Radix Astragali, barrenwort, the fruit of Chinese wolfberry, cinnamomum cassia extract 38-72, the described Radix Astragali, barrenwort, the fruit of Chinese wolfberry and Chinese cassia tree consumption weight ratio are 3: 3: 2: 2, described termite extract is that the employing enzymatic isolation method filters and gets, the pH value of enzymolysis liquid is 6.8-7.3 during enzymolysis, the described Radix Astragali, barrenwort, matrimony vine, cinnamomum cassia extract is to adopt the hot reflux extraction to filter and get, its temperature is controlled at 80-130 ℃, and the time is 150-210 minute.
2. health food according to claim 1, the consumption weight portion proportioning that it is characterized in that used material is as follows: termite extract 40-55, the Radix Astragali, barrenwort, the fruit of Chinese wolfberry, cinnamomum cassia extract 45-65, the described Radix Astragali, barrenwort, the fruit of Chinese wolfberry and Chinese cassia tree consumption weight ratio are 3: 3: 2: 2.
3. health food according to claim 1, feature is that the consumption weight portion proportioning of used material is as follows: termite extract 48, the Radix Astragali, barrenwort, the fruit of Chinese wolfberry, cinnamomum cassia extract 52, the described Radix Astragali, barrenwort, the fruit of Chinese wolfberry and Chinese cassia tree consumption weight ratio are 3: 3: 2: 2.
4. method for preparing claim 1,2,3 arbitrary described health foods:
(1) with termite extract and the Radix Astragali, barrenwort, the fruit of Chinese wolfberry, cinnamomum cassia extract mixes, get mixed liquor, after the relative density that more above-mentioned mixed liquor is concentrated to 60 ℃ of surveys is 1.08-1.10, add 95% edible alcohol that volume equates, stir, make pure content reach 46-68%, left standstill 24 hours, get supernatant, filter, behind the filtrate decompression recovered alcohol, place for subsequent use, described termite extract is that the employing enzymatic isolation method filters and gets, the pH value of enzymolysis liquid is 6.8-7.3 during enzymolysis, the described Radix Astragali, barrenwort, matrimony vine, cinnamomum cassia extract is to adopt the hot reflux extraction to filter and get, and its temperature is controlled at 80-130 ℃, time is 150-210 minute, the described Radix Astragali, barrenwort, the fruit of Chinese wolfberry and Chinese cassia tree consumption weight ratio are 3: 3: 2: 2;
(2) precipitation solution is concentrated, the relative density that is concentrated into 60 ℃ of surveys is 1.08-1.10, gets clearly cream;
(3) above-mentioned clear cream is carried out spray-drying, get dry powder;
(4) dry powder with gained places fluidized granulation mechanism grain, whole grain, gets dried particle;
(5) dried particle is filled at the automatic capsule filling machine, the loading amount specification is 0.45g/ grain or 0.25g/ grain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102478698A CN102370162B (en) | 2010-08-07 | 2010-08-07 | Health-care food for relieving physical fatigue prepared by taking termite as main raw material |
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|---|---|---|---|
| CN2010102478698A CN102370162B (en) | 2010-08-07 | 2010-08-07 | Health-care food for relieving physical fatigue prepared by taking termite as main raw material |
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| CN102370162A CN102370162A (en) | 2012-03-14 |
| CN102370162B true CN102370162B (en) | 2013-03-27 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104312874B (en) * | 2014-11-12 | 2016-08-24 | 江西三琦药业有限公司 | A kind of health liquor made for primary raw material with black wing Soil termites |
| CN104546925B (en) * | 2015-02-06 | 2018-05-25 | 江西中天医药生物有限公司 | Termite capsule and preparation method thereof |
| CN104546926B (en) * | 2015-02-06 | 2018-05-25 | 江西中天医药生物有限公司 | Termite tea and preparation method thereof |
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| CN1234401C (en) * | 2004-02-10 | 2006-01-04 | 广西来宾金钱草药业有限公司 | Bi-ant contained dampness dispelling and collaterals dredging medicinal capsule |
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