CN102369293B - 肾损伤和肾衰竭的诊断及预后 - Google Patents

肾损伤和肾衰竭的诊断及预后 Download PDF

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Publication number
CN102369293B
CN102369293B CN201080013522.5A CN201080013522A CN102369293B CN 102369293 B CN102369293 B CN 102369293B CN 201080013522 A CN201080013522 A CN 201080013522A CN 102369293 B CN102369293 B CN 102369293B
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renal
subject
kidney
experimenter
stage
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Chinese (zh)
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CN102369293A (zh
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J·安德贝里
J·格雷
P·麦克弗森
K·中村
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Astute Medical Inc
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Astute Medical Inc
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Priority to CN201611051979.0A priority Critical patent/CN106546752A/zh
Priority to CN201410171245.0A priority patent/CN104111336B/zh
Publication of CN102369293A publication Critical patent/CN102369293A/zh
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201080013522.5A 2009-02-06 2010-02-05 肾损伤和肾衰竭的诊断及预后 Expired - Fee Related CN102369293B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201611051979.0A CN106546752A (zh) 2009-02-06 2010-02-05 肾损伤和肾衰竭的诊断及预后
CN201410171245.0A CN104111336B (zh) 2009-02-06 2010-02-05 肾损伤和肾衰竭的诊断及预后

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US15039309P 2009-02-06 2009-02-06
US15037209P 2009-02-06 2009-02-06
US15037409P 2009-02-06 2009-02-06
US61/150,393 2009-02-06
US61/150,372 2009-02-06
US61/150,374 2009-02-06
US16240209P 2009-03-23 2009-03-23
US16239609P 2009-03-23 2009-03-23
US61/162,402 2009-03-23
US61/162,396 2009-03-23
US16633309P 2009-04-03 2009-04-03
US61/166,333 2009-04-03
PCT/US2010/023292 WO2010091231A1 (en) 2009-02-06 2010-02-05 Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN201611051979.0A Division CN106546752A (zh) 2009-02-06 2010-02-05 肾损伤和肾衰竭的诊断及预后
CN201410171245.0A Division CN104111336B (zh) 2009-02-06 2010-02-05 肾损伤和肾衰竭的诊断及预后

Publications (2)

Publication Number Publication Date
CN102369293A CN102369293A (zh) 2012-03-07
CN102369293B true CN102369293B (zh) 2014-05-28

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Application Number Title Priority Date Filing Date
CN201080013522.5A Expired - Fee Related CN102369293B (zh) 2009-02-06 2010-02-05 肾损伤和肾衰竭的诊断及预后
CN201611051979.0A Pending CN106546752A (zh) 2009-02-06 2010-02-05 肾损伤和肾衰竭的诊断及预后
CN201410171245.0A Expired - Fee Related CN104111336B (zh) 2009-02-06 2010-02-05 肾损伤和肾衰竭的诊断及预后

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CN201611051979.0A Pending CN106546752A (zh) 2009-02-06 2010-02-05 肾损伤和肾衰竭的诊断及预后
CN201410171245.0A Expired - Fee Related CN104111336B (zh) 2009-02-06 2010-02-05 肾损伤和肾衰竭的诊断及预后

Country Status (11)

Country Link
US (1) US20160123996A1 (enExample)
EP (1) EP2393937A4 (enExample)
JP (3) JP2012517592A (enExample)
CN (3) CN102369293B (enExample)
AU (1) AU2010210535B2 (enExample)
BR (1) BRPI1007917A2 (enExample)
CA (1) CA2751424A1 (enExample)
HK (1) HK1200218A1 (enExample)
MX (1) MX2011008323A (enExample)
NZ (1) NZ630621A (enExample)
WO (1) WO2010091231A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9057735B2 (en) 2008-08-29 2015-06-16 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA2766228A1 (en) * 2009-07-02 2011-01-06 Mosaiques Diagnostics And Therapeutics Ag Process and markers for the diagnosis of acute renal failure
JP2013541005A (ja) * 2010-09-24 2013-11-07 アスチュート メディカル,インコーポレイテッド ヒアルロン酸を使用した腎損傷の評価のための方法ならびに組成物
EP2882767B1 (en) * 2012-08-11 2023-07-12 Astute Medical, Inc. Evaluating renal injury using hyaluronic acid
HK1219129A1 (zh) * 2013-01-29 2017-03-24 阿斯图特医药公司 用於肾损伤和肾衰竭的诊断及预後的方法和组合物
CN105917229B (zh) * 2013-12-03 2019-04-26 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断和预后的方法和组合物
CL2015003047A1 (es) * 2015-10-15 2016-06-17 Univ Chile Método ex vivo para detectar precozmente injuria renal aguda en pacientes críticos, que comprende la mediciom en una muestra de tres proteinas como biomarcadores, factor de crecimiento fibroblástico 23, klotho y eritropoyetina
CN105466984B (zh) * 2016-01-14 2018-12-28 郑以山 用于肾脏非显性损伤的预警装置及其使用方法
WO2017130985A1 (ja) * 2016-01-29 2017-08-03 株式会社国際電気通信基礎技術研究所 腎機能の評価装置、腎疾患の合併症の発症の予測装置、およびリン摂取量推定装置
CN106845140A (zh) * 2017-03-01 2017-06-13 重庆工商大学 一种基于尿比重和尿量监测的肾衰竭预警方法及系统
MX2019014441A (es) * 2017-05-30 2020-02-10 Sphingotec Gmbh Un metodo in vitro para diagnosticar o monitorear la funcion renal o diagnosticar disfuncion renal.
CN109897108B (zh) * 2019-03-11 2021-04-02 上海恒赛生物科技有限公司 抗人内皮蛋白c受体的羊驼单域抗体及应用
EP3881862A1 (de) * 2020-03-18 2021-09-22 Pharis Biotec GmbH Polypeptid zur therapie von glomerulären nierenerkrankungen und analyse des verlaufes und prognose der abhängigen syndrome

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1311691A (zh) * 1998-08-19 2001-09-05 味之素株式会社 抗凝剂和人源化抗冯·维勒布兰德氏因子的单克隆抗体
US6861404B1 (en) * 1996-05-06 2005-03-01 Curis, Inc. Therapies for chronic renal failure
US20070154897A1 (en) * 2006-01-02 2007-07-05 National Defense Medical Center Biomarkers for kidney diseases and method for using same
US20080038269A1 (en) * 2006-05-25 2008-02-14 Mount Sinai Hospital Methods for detecting and treating kidney disease
US20080254485A1 (en) * 2006-11-14 2008-10-16 Biosite Incorporated Methods And Compositions For Monitoring And Risk Prediction In Cardiorenal Syndrome

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JP3569577B2 (ja) * 1995-09-04 2004-09-22 株式会社いかがく 腎・尿路系疾患の鑑別診断用キット
JP2003030100A (ja) * 2001-07-12 2003-01-31 Fuji Xerox Co Ltd インターネット情報提供システムおよびインターネット情報提供方法
ES2268961B1 (es) * 2005-03-17 2008-03-16 Proyecto De Biomedicina Cima, S.L. Nueva proteina epcr soluble de origen no proteolitico y su uso.
US7833732B2 (en) * 2005-07-21 2010-11-16 The John Hopkins University Acute renal injury
US7662578B2 (en) * 2006-04-21 2010-02-16 Children's Hospital Medical Center Method and kit for the early detection of impaired renal status
GB0617429D0 (en) * 2006-09-05 2006-10-18 Electrophoretics Ltd Markers of renal transplant rejection and renal damage
JP5661457B2 (ja) * 2007-06-06 2015-01-28 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. 腎疾患の予測診断

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861404B1 (en) * 1996-05-06 2005-03-01 Curis, Inc. Therapies for chronic renal failure
CN1311691A (zh) * 1998-08-19 2001-09-05 味之素株式会社 抗凝剂和人源化抗冯·维勒布兰德氏因子的单克隆抗体
US20070154897A1 (en) * 2006-01-02 2007-07-05 National Defense Medical Center Biomarkers for kidney diseases and method for using same
US20080038269A1 (en) * 2006-05-25 2008-02-14 Mount Sinai Hospital Methods for detecting and treating kidney disease
US20080254485A1 (en) * 2006-11-14 2008-10-16 Biosite Incorporated Methods And Compositions For Monitoring And Risk Prediction In Cardiorenal Syndrome

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《Early detection of acute renal failure by serum cystatin C》;Herget-Rosenthal et al;《Kidney International》;20041231;第66卷;第1116页左栏第2段,第1117页左栏第2段 *
《慢性肾功能衰竭患者血浆血管性血友病因子含量检测及临床意义》;张翠萍等;《临床荟萃》;20071020;第22卷(第20期);摘要部分以及正文第1465页左栏第1段,第1466页右栏第2段 *

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Publication number Publication date
HK1162617A1 (en) 2012-08-31
CN106546752A (zh) 2017-03-29
CN104111336A (zh) 2014-10-22
AU2010210535B2 (en) 2015-12-10
CN102369293A (zh) 2012-03-07
MX2011008323A (es) 2011-09-21
WO2010091231A1 (en) 2010-08-12
JP2016194526A (ja) 2016-11-17
AU2010210535A1 (en) 2011-09-15
BRPI1007917A2 (pt) 2019-09-24
HK1200218A1 (en) 2015-07-31
EP2393937A1 (en) 2011-12-14
JP2012517592A (ja) 2012-08-02
US20160123996A1 (en) 2016-05-05
CA2751424A1 (en) 2010-08-12
CN104111336B (zh) 2017-01-18
EP2393937A4 (en) 2012-08-08
JP2015096870A (ja) 2015-05-21
NZ630621A (en) 2016-03-31

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