CN102369293B - 肾损伤和肾衰竭的诊断及预后 - Google Patents
肾损伤和肾衰竭的诊断及预后 Download PDFInfo
- Publication number
- CN102369293B CN102369293B CN201080013522.5A CN201080013522A CN102369293B CN 102369293 B CN102369293 B CN 102369293B CN 201080013522 A CN201080013522 A CN 201080013522A CN 102369293 B CN102369293 B CN 102369293B
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- China
- Prior art keywords
- renal
- subject
- kidney
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- stage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611051979.0A CN106546752A (zh) | 2009-02-06 | 2010-02-05 | 肾损伤和肾衰竭的诊断及预后 |
| CN201410171245.0A CN104111336B (zh) | 2009-02-06 | 2010-02-05 | 肾损伤和肾衰竭的诊断及预后 |
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15039309P | 2009-02-06 | 2009-02-06 | |
| US15037209P | 2009-02-06 | 2009-02-06 | |
| US15037409P | 2009-02-06 | 2009-02-06 | |
| US61/150,393 | 2009-02-06 | ||
| US61/150,372 | 2009-02-06 | ||
| US61/150,374 | 2009-02-06 | ||
| US16240209P | 2009-03-23 | 2009-03-23 | |
| US16239609P | 2009-03-23 | 2009-03-23 | |
| US61/162,402 | 2009-03-23 | ||
| US61/162,396 | 2009-03-23 | ||
| US16633309P | 2009-04-03 | 2009-04-03 | |
| US61/166,333 | 2009-04-03 | ||
| PCT/US2010/023292 WO2010091231A1 (en) | 2009-02-06 | 2010-02-05 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611051979.0A Division CN106546752A (zh) | 2009-02-06 | 2010-02-05 | 肾损伤和肾衰竭的诊断及预后 |
| CN201410171245.0A Division CN104111336B (zh) | 2009-02-06 | 2010-02-05 | 肾损伤和肾衰竭的诊断及预后 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102369293A CN102369293A (zh) | 2012-03-07 |
| CN102369293B true CN102369293B (zh) | 2014-05-28 |
Family
ID=42542388
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080013522.5A Expired - Fee Related CN102369293B (zh) | 2009-02-06 | 2010-02-05 | 肾损伤和肾衰竭的诊断及预后 |
| CN201611051979.0A Pending CN106546752A (zh) | 2009-02-06 | 2010-02-05 | 肾损伤和肾衰竭的诊断及预后 |
| CN201410171245.0A Expired - Fee Related CN104111336B (zh) | 2009-02-06 | 2010-02-05 | 肾损伤和肾衰竭的诊断及预后 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611051979.0A Pending CN106546752A (zh) | 2009-02-06 | 2010-02-05 | 肾损伤和肾衰竭的诊断及预后 |
| CN201410171245.0A Expired - Fee Related CN104111336B (zh) | 2009-02-06 | 2010-02-05 | 肾损伤和肾衰竭的诊断及预后 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20160123996A1 (enExample) |
| EP (1) | EP2393937A4 (enExample) |
| JP (3) | JP2012517592A (enExample) |
| CN (3) | CN102369293B (enExample) |
| AU (1) | AU2010210535B2 (enExample) |
| BR (1) | BRPI1007917A2 (enExample) |
| CA (1) | CA2751424A1 (enExample) |
| HK (1) | HK1200218A1 (enExample) |
| MX (1) | MX2011008323A (enExample) |
| NZ (1) | NZ630621A (enExample) |
| WO (1) | WO2010091231A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9057735B2 (en) | 2008-08-29 | 2015-06-16 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA2766228A1 (en) * | 2009-07-02 | 2011-01-06 | Mosaiques Diagnostics And Therapeutics Ag | Process and markers for the diagnosis of acute renal failure |
| JP2013541005A (ja) * | 2010-09-24 | 2013-11-07 | アスチュート メディカル,インコーポレイテッド | ヒアルロン酸を使用した腎損傷の評価のための方法ならびに組成物 |
| EP2882767B1 (en) * | 2012-08-11 | 2023-07-12 | Astute Medical, Inc. | Evaluating renal injury using hyaluronic acid |
| HK1219129A1 (zh) * | 2013-01-29 | 2017-03-24 | 阿斯图特医药公司 | 用於肾损伤和肾衰竭的诊断及预後的方法和组合物 |
| CN105917229B (zh) * | 2013-12-03 | 2019-04-26 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| CL2015003047A1 (es) * | 2015-10-15 | 2016-06-17 | Univ Chile | Método ex vivo para detectar precozmente injuria renal aguda en pacientes críticos, que comprende la mediciom en una muestra de tres proteinas como biomarcadores, factor de crecimiento fibroblástico 23, klotho y eritropoyetina |
| CN105466984B (zh) * | 2016-01-14 | 2018-12-28 | 郑以山 | 用于肾脏非显性损伤的预警装置及其使用方法 |
| WO2017130985A1 (ja) * | 2016-01-29 | 2017-08-03 | 株式会社国際電気通信基礎技術研究所 | 腎機能の評価装置、腎疾患の合併症の発症の予測装置、およびリン摂取量推定装置 |
| CN106845140A (zh) * | 2017-03-01 | 2017-06-13 | 重庆工商大学 | 一种基于尿比重和尿量监测的肾衰竭预警方法及系统 |
| MX2019014441A (es) * | 2017-05-30 | 2020-02-10 | Sphingotec Gmbh | Un metodo in vitro para diagnosticar o monitorear la funcion renal o diagnosticar disfuncion renal. |
| CN109897108B (zh) * | 2019-03-11 | 2021-04-02 | 上海恒赛生物科技有限公司 | 抗人内皮蛋白c受体的羊驼单域抗体及应用 |
| EP3881862A1 (de) * | 2020-03-18 | 2021-09-22 | Pharis Biotec GmbH | Polypeptid zur therapie von glomerulären nierenerkrankungen und analyse des verlaufes und prognose der abhängigen syndrome |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1311691A (zh) * | 1998-08-19 | 2001-09-05 | 味之素株式会社 | 抗凝剂和人源化抗冯·维勒布兰德氏因子的单克隆抗体 |
| US6861404B1 (en) * | 1996-05-06 | 2005-03-01 | Curis, Inc. | Therapies for chronic renal failure |
| US20070154897A1 (en) * | 2006-01-02 | 2007-07-05 | National Defense Medical Center | Biomarkers for kidney diseases and method for using same |
| US20080038269A1 (en) * | 2006-05-25 | 2008-02-14 | Mount Sinai Hospital | Methods for detecting and treating kidney disease |
| US20080254485A1 (en) * | 2006-11-14 | 2008-10-16 | Biosite Incorporated | Methods And Compositions For Monitoring And Risk Prediction In Cardiorenal Syndrome |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3569577B2 (ja) * | 1995-09-04 | 2004-09-22 | 株式会社いかがく | 腎・尿路系疾患の鑑別診断用キット |
| JP2003030100A (ja) * | 2001-07-12 | 2003-01-31 | Fuji Xerox Co Ltd | インターネット情報提供システムおよびインターネット情報提供方法 |
| ES2268961B1 (es) * | 2005-03-17 | 2008-03-16 | Proyecto De Biomedicina Cima, S.L. | Nueva proteina epcr soluble de origen no proteolitico y su uso. |
| US7833732B2 (en) * | 2005-07-21 | 2010-11-16 | The John Hopkins University | Acute renal injury |
| US7662578B2 (en) * | 2006-04-21 | 2010-02-16 | Children's Hospital Medical Center | Method and kit for the early detection of impaired renal status |
| GB0617429D0 (en) * | 2006-09-05 | 2006-10-18 | Electrophoretics Ltd | Markers of renal transplant rejection and renal damage |
| JP5661457B2 (ja) * | 2007-06-06 | 2015-01-28 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. | 腎疾患の予測診断 |
-
2010
- 2010-02-05 EP EP10739150A patent/EP2393937A4/en not_active Withdrawn
- 2010-02-05 AU AU2010210535A patent/AU2010210535B2/en not_active Ceased
- 2010-02-05 JP JP2011549275A patent/JP2012517592A/ja active Pending
- 2010-02-05 CN CN201080013522.5A patent/CN102369293B/zh not_active Expired - Fee Related
- 2010-02-05 WO PCT/US2010/023292 patent/WO2010091231A1/en not_active Ceased
- 2010-02-05 NZ NZ630621A patent/NZ630621A/en not_active IP Right Cessation
- 2010-02-05 CN CN201611051979.0A patent/CN106546752A/zh active Pending
- 2010-02-05 BR BRPI1007917A patent/BRPI1007917A2/pt not_active IP Right Cessation
- 2010-02-05 MX MX2011008323A patent/MX2011008323A/es active IP Right Grant
- 2010-02-05 CA CA2751424A patent/CA2751424A1/en not_active Abandoned
- 2010-02-05 CN CN201410171245.0A patent/CN104111336B/zh not_active Expired - Fee Related
-
2015
- 2015-01-20 HK HK15100634.5A patent/HK1200218A1/xx unknown
- 2015-01-27 JP JP2015013153A patent/JP2015096870A/ja active Pending
-
2016
- 2016-01-04 US US14/987,569 patent/US20160123996A1/en not_active Abandoned
- 2016-07-04 JP JP2016132688A patent/JP2016194526A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6861404B1 (en) * | 1996-05-06 | 2005-03-01 | Curis, Inc. | Therapies for chronic renal failure |
| CN1311691A (zh) * | 1998-08-19 | 2001-09-05 | 味之素株式会社 | 抗凝剂和人源化抗冯·维勒布兰德氏因子的单克隆抗体 |
| US20070154897A1 (en) * | 2006-01-02 | 2007-07-05 | National Defense Medical Center | Biomarkers for kidney diseases and method for using same |
| US20080038269A1 (en) * | 2006-05-25 | 2008-02-14 | Mount Sinai Hospital | Methods for detecting and treating kidney disease |
| US20080254485A1 (en) * | 2006-11-14 | 2008-10-16 | Biosite Incorporated | Methods And Compositions For Monitoring And Risk Prediction In Cardiorenal Syndrome |
Non-Patent Citations (2)
| Title |
|---|
| 《Early detection of acute renal failure by serum cystatin C》;Herget-Rosenthal et al;《Kidney International》;20041231;第66卷;第1116页左栏第2段,第1117页左栏第2段 * |
| 《慢性肾功能衰竭患者血浆血管性血友病因子含量检测及临床意义》;张翠萍等;《临床荟萃》;20071020;第22卷(第20期);摘要部分以及正文第1465页左栏第1段,第1466页右栏第2段 * |
Also Published As
| Publication number | Publication date |
|---|---|
| HK1162617A1 (en) | 2012-08-31 |
| CN106546752A (zh) | 2017-03-29 |
| CN104111336A (zh) | 2014-10-22 |
| AU2010210535B2 (en) | 2015-12-10 |
| CN102369293A (zh) | 2012-03-07 |
| MX2011008323A (es) | 2011-09-21 |
| WO2010091231A1 (en) | 2010-08-12 |
| JP2016194526A (ja) | 2016-11-17 |
| AU2010210535A1 (en) | 2011-09-15 |
| BRPI1007917A2 (pt) | 2019-09-24 |
| HK1200218A1 (en) | 2015-07-31 |
| EP2393937A1 (en) | 2011-12-14 |
| JP2012517592A (ja) | 2012-08-02 |
| US20160123996A1 (en) | 2016-05-05 |
| CA2751424A1 (en) | 2010-08-12 |
| CN104111336B (zh) | 2017-01-18 |
| EP2393937A4 (en) | 2012-08-08 |
| JP2015096870A (ja) | 2015-05-21 |
| NZ630621A (en) | 2016-03-31 |
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