NZ630621A - Methods and compositions for diagnosis and prognosis of renal injury and renal failure - Google Patents
Methods and compositions for diagnosis and prognosis of renal injury and renal failureInfo
- Publication number
- NZ630621A NZ630621A NZ630621A NZ63062110A NZ630621A NZ 630621 A NZ630621 A NZ 630621A NZ 630621 A NZ630621 A NZ 630621A NZ 63062110 A NZ63062110 A NZ 63062110A NZ 630621 A NZ630621 A NZ 630621A
- Authority
- NZ
- New Zealand
- Prior art keywords
- prognosis
- subject
- determining
- threshold
- event
- Prior art date
Links
- 206010061481 Renal injury Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000004393 prognosis Methods 0.000 title abstract 2
- 208000001647 Renal Insufficiency Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 201000006370 kidney failure Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 108010063045 Lactoferrin Proteins 0.000 abstract 3
- 238000003556 assay Methods 0.000 abstract 3
- 102100032241 Lactotransferrin Human genes 0.000 abstract 2
- 210000001124 body fluid Anatomy 0.000 abstract 2
- 239000010839 body fluid Substances 0.000 abstract 2
- 208000037806 kidney injury Diseases 0.000 abstract 2
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 abstract 2
- 229940078795 lactoferrin Drugs 0.000 abstract 2
- 235000021242 lactoferrin Nutrition 0.000 abstract 2
- 102000012174 Lactotransferrin Human genes 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000013517 stratification Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15037409P | 2009-02-06 | 2009-02-06 | |
| US15039309P | 2009-02-06 | 2009-02-06 | |
| US15037209P | 2009-02-06 | 2009-02-06 | |
| US16240209P | 2009-03-23 | 2009-03-23 | |
| US16239609P | 2009-03-23 | 2009-03-23 | |
| US16633309P | 2009-04-03 | 2009-04-03 | |
| NZ609666A NZ609666A (en) | 2009-02-06 | 2010-02-05 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ630621A true NZ630621A (en) | 2016-03-31 |
Family
ID=42542388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ630621A NZ630621A (en) | 2009-02-06 | 2010-02-05 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20160123996A1 (enExample) |
| EP (1) | EP2393937A4 (enExample) |
| JP (3) | JP2012517592A (enExample) |
| CN (3) | CN102369293B (enExample) |
| AU (1) | AU2010210535B2 (enExample) |
| BR (1) | BRPI1007917A2 (enExample) |
| CA (1) | CA2751424A1 (enExample) |
| HK (1) | HK1200218A1 (enExample) |
| MX (1) | MX2011008323A (enExample) |
| NZ (1) | NZ630621A (enExample) |
| WO (1) | WO2010091231A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9057735B2 (en) | 2008-08-29 | 2015-06-16 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA2766228A1 (en) * | 2009-07-02 | 2011-01-06 | Mosaiques Diagnostics And Therapeutics Ag | Process and markers for the diagnosis of acute renal failure |
| JP2013541005A (ja) * | 2010-09-24 | 2013-11-07 | アスチュート メディカル,インコーポレイテッド | ヒアルロン酸を使用した腎損傷の評価のための方法ならびに組成物 |
| EP2882767B1 (en) * | 2012-08-11 | 2023-07-12 | Astute Medical, Inc. | Evaluating renal injury using hyaluronic acid |
| HK1219129A1 (zh) * | 2013-01-29 | 2017-03-24 | 阿斯图特医药公司 | 用於肾损伤和肾衰竭的诊断及预後的方法和组合物 |
| CN105917229B (zh) * | 2013-12-03 | 2019-04-26 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| CL2015003047A1 (es) * | 2015-10-15 | 2016-06-17 | Univ Chile | Método ex vivo para detectar precozmente injuria renal aguda en pacientes críticos, que comprende la mediciom en una muestra de tres proteinas como biomarcadores, factor de crecimiento fibroblástico 23, klotho y eritropoyetina |
| CN105466984B (zh) * | 2016-01-14 | 2018-12-28 | 郑以山 | 用于肾脏非显性损伤的预警装置及其使用方法 |
| WO2017130985A1 (ja) * | 2016-01-29 | 2017-08-03 | 株式会社国際電気通信基礎技術研究所 | 腎機能の評価装置、腎疾患の合併症の発症の予測装置、およびリン摂取量推定装置 |
| CN106845140A (zh) * | 2017-03-01 | 2017-06-13 | 重庆工商大学 | 一种基于尿比重和尿量监测的肾衰竭预警方法及系统 |
| MX2019014441A (es) * | 2017-05-30 | 2020-02-10 | Sphingotec Gmbh | Un metodo in vitro para diagnosticar o monitorear la funcion renal o diagnosticar disfuncion renal. |
| CN109897108B (zh) * | 2019-03-11 | 2021-04-02 | 上海恒赛生物科技有限公司 | 抗人内皮蛋白c受体的羊驼单域抗体及应用 |
| EP3881862A1 (de) * | 2020-03-18 | 2021-09-22 | Pharis Biotec GmbH | Polypeptid zur therapie von glomerulären nierenerkrankungen und analyse des verlaufes und prognose der abhängigen syndrome |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3569577B2 (ja) * | 1995-09-04 | 2004-09-22 | 株式会社いかがく | 腎・尿路系疾患の鑑別診断用キット |
| US6498142B1 (en) * | 1996-05-06 | 2002-12-24 | Curis, Inc. | Morphogen treatment for chronic renal failure |
| US6228360B1 (en) * | 1998-08-19 | 2001-05-08 | Ajinomoto Co., Inc. | Antithrombotic agent and humanized anti-von Willebrand factor monoclonal antibody |
| JP2003030100A (ja) * | 2001-07-12 | 2003-01-31 | Fuji Xerox Co Ltd | インターネット情報提供システムおよびインターネット情報提供方法 |
| ES2268961B1 (es) * | 2005-03-17 | 2008-03-16 | Proyecto De Biomedicina Cima, S.L. | Nueva proteina epcr soluble de origen no proteolitico y su uso. |
| US7833732B2 (en) * | 2005-07-21 | 2010-11-16 | The John Hopkins University | Acute renal injury |
| TW200726845A (en) * | 2006-01-02 | 2007-07-16 | Nat Defense Medical Ct | Biomarker molecular of renal illness and detecting method for the same |
| US7662578B2 (en) * | 2006-04-21 | 2010-02-16 | Children's Hospital Medical Center | Method and kit for the early detection of impaired renal status |
| US20080038269A1 (en) * | 2006-05-25 | 2008-02-14 | Mount Sinai Hospital | Methods for detecting and treating kidney disease |
| GB0617429D0 (en) * | 2006-09-05 | 2006-10-18 | Electrophoretics Ltd | Markers of renal transplant rejection and renal damage |
| EP2095107B1 (en) * | 2006-11-14 | 2014-07-02 | Alere San Diego, Inc. | Methods for risk assignment |
| JP5661457B2 (ja) * | 2007-06-06 | 2015-01-28 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. | 腎疾患の予測診断 |
-
2010
- 2010-02-05 EP EP10739150A patent/EP2393937A4/en not_active Withdrawn
- 2010-02-05 AU AU2010210535A patent/AU2010210535B2/en not_active Ceased
- 2010-02-05 JP JP2011549275A patent/JP2012517592A/ja active Pending
- 2010-02-05 CN CN201080013522.5A patent/CN102369293B/zh not_active Expired - Fee Related
- 2010-02-05 WO PCT/US2010/023292 patent/WO2010091231A1/en not_active Ceased
- 2010-02-05 NZ NZ630621A patent/NZ630621A/en not_active IP Right Cessation
- 2010-02-05 CN CN201611051979.0A patent/CN106546752A/zh active Pending
- 2010-02-05 BR BRPI1007917A patent/BRPI1007917A2/pt not_active IP Right Cessation
- 2010-02-05 MX MX2011008323A patent/MX2011008323A/es active IP Right Grant
- 2010-02-05 CA CA2751424A patent/CA2751424A1/en not_active Abandoned
- 2010-02-05 CN CN201410171245.0A patent/CN104111336B/zh not_active Expired - Fee Related
-
2015
- 2015-01-20 HK HK15100634.5A patent/HK1200218A1/xx unknown
- 2015-01-27 JP JP2015013153A patent/JP2015096870A/ja active Pending
-
2016
- 2016-01-04 US US14/987,569 patent/US20160123996A1/en not_active Abandoned
- 2016-07-04 JP JP2016132688A patent/JP2016194526A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HK1162617A1 (en) | 2012-08-31 |
| CN106546752A (zh) | 2017-03-29 |
| CN104111336A (zh) | 2014-10-22 |
| AU2010210535B2 (en) | 2015-12-10 |
| CN102369293A (zh) | 2012-03-07 |
| MX2011008323A (es) | 2011-09-21 |
| WO2010091231A1 (en) | 2010-08-12 |
| JP2016194526A (ja) | 2016-11-17 |
| AU2010210535A1 (en) | 2011-09-15 |
| BRPI1007917A2 (pt) | 2019-09-24 |
| CN102369293B (zh) | 2014-05-28 |
| HK1200218A1 (en) | 2015-07-31 |
| EP2393937A1 (en) | 2011-12-14 |
| JP2012517592A (ja) | 2012-08-02 |
| US20160123996A1 (en) | 2016-05-05 |
| CA2751424A1 (en) | 2010-08-12 |
| CN104111336B (zh) | 2017-01-18 |
| EP2393937A4 (en) | 2012-08-08 |
| JP2015096870A (ja) | 2015-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 05 FEB 2017 BY FB RICE Effective date: 20160704 |
|
| LAPS | Patent lapsed |