JP2012517592A - 腎損傷および腎不全の診断および予後診断のための方法および組成物 - Google Patents

腎損傷および腎不全の診断および予後診断のための方法および組成物 Download PDF

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JP2012517592A
JP2012517592A JP2011549275A JP2011549275A JP2012517592A JP 2012517592 A JP2012517592 A JP 2012517592A JP 2011549275 A JP2011549275 A JP 2011549275A JP 2011549275 A JP2011549275 A JP 2011549275A JP 2012517592 A JP2012517592 A JP 2012517592A
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threshold
kidney
future
renal
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JP2012517592A5 (enExample
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アンダーバーグ,ジョセフ
グレイ,ジェフ
マクファーソン,ポール
ナカムラ,ケビン
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アスチュート メディカル,インコーポレイテッド
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011549275A 2009-02-06 2010-02-05 腎損傷および腎不全の診断および予後診断のための方法および組成物 Pending JP2012517592A (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US15039309P 2009-02-06 2009-02-06
US15037209P 2009-02-06 2009-02-06
US15037409P 2009-02-06 2009-02-06
US61/150,393 2009-02-06
US61/150,372 2009-02-06
US61/150,374 2009-02-06
US16240209P 2009-03-23 2009-03-23
US16239609P 2009-03-23 2009-03-23
US61/162,402 2009-03-23
US61/162,396 2009-03-23
US16633309P 2009-04-03 2009-04-03
US61/166,333 2009-04-03
PCT/US2010/023292 WO2010091231A1 (en) 2009-02-06 2010-02-05 Methods and compositions for diagnosis and prognosis of renal injury and renal failure

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JP2015013153A Division JP2015096870A (ja) 2009-02-06 2015-01-27 腎損傷および腎不全の診断および予後診断のための方法および組成物

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JP2012517592A true JP2012517592A (ja) 2012-08-02
JP2012517592A5 JP2012517592A5 (enExample) 2013-03-28

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JP2011549275A Pending JP2012517592A (ja) 2009-02-06 2010-02-05 腎損傷および腎不全の診断および予後診断のための方法および組成物
JP2015013153A Pending JP2015096870A (ja) 2009-02-06 2015-01-27 腎損傷および腎不全の診断および予後診断のための方法および組成物
JP2016132688A Pending JP2016194526A (ja) 2009-02-06 2016-07-04 腎損傷および腎不全の診断および予後診断のための方法および組成物

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JP2015013153A Pending JP2015096870A (ja) 2009-02-06 2015-01-27 腎損傷および腎不全の診断および予後診断のための方法および組成物
JP2016132688A Pending JP2016194526A (ja) 2009-02-06 2016-07-04 腎損傷および腎不全の診断および予後診断のための方法および組成物

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Country Link
US (1) US20160123996A1 (enExample)
EP (1) EP2393937A4 (enExample)
JP (3) JP2012517592A (enExample)
CN (3) CN102369293B (enExample)
AU (1) AU2010210535B2 (enExample)
BR (1) BRPI1007917A2 (enExample)
CA (1) CA2751424A1 (enExample)
HK (1) HK1200218A1 (enExample)
MX (1) MX2011008323A (enExample)
NZ (1) NZ630621A (enExample)
WO (1) WO2010091231A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016505860A (ja) * 2013-01-29 2016-02-25 アスチュート メディカル,インコーポレイテッド 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9057735B2 (en) 2008-08-29 2015-06-16 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA2766228A1 (en) * 2009-07-02 2011-01-06 Mosaiques Diagnostics And Therapeutics Ag Process and markers for the diagnosis of acute renal failure
JP2013541005A (ja) * 2010-09-24 2013-11-07 アスチュート メディカル,インコーポレイテッド ヒアルロン酸を使用した腎損傷の評価のための方法ならびに組成物
EP2882767B1 (en) * 2012-08-11 2023-07-12 Astute Medical, Inc. Evaluating renal injury using hyaluronic acid
CN105917229B (zh) * 2013-12-03 2019-04-26 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断和预后的方法和组合物
CL2015003047A1 (es) * 2015-10-15 2016-06-17 Univ Chile Método ex vivo para detectar precozmente injuria renal aguda en pacientes críticos, que comprende la mediciom en una muestra de tres proteinas como biomarcadores, factor de crecimiento fibroblástico 23, klotho y eritropoyetina
CN105466984B (zh) * 2016-01-14 2018-12-28 郑以山 用于肾脏非显性损伤的预警装置及其使用方法
WO2017130985A1 (ja) * 2016-01-29 2017-08-03 株式会社国際電気通信基礎技術研究所 腎機能の評価装置、腎疾患の合併症の発症の予測装置、およびリン摂取量推定装置
CN106845140A (zh) * 2017-03-01 2017-06-13 重庆工商大学 一种基于尿比重和尿量监测的肾衰竭预警方法及系统
MX2019014441A (es) * 2017-05-30 2020-02-10 Sphingotec Gmbh Un metodo in vitro para diagnosticar o monitorear la funcion renal o diagnosticar disfuncion renal.
CN109897108B (zh) * 2019-03-11 2021-04-02 上海恒赛生物科技有限公司 抗人内皮蛋白c受体的羊驼单域抗体及应用
EP3881862A1 (de) * 2020-03-18 2021-09-22 Pharis Biotec GmbH Polypeptid zur therapie von glomerulären nierenerkrankungen und analyse des verlaufes und prognose der abhängigen syndrome

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080254485A1 (en) * 2006-11-14 2008-10-16 Biosite Incorporated Methods And Compositions For Monitoring And Risk Prediction In Cardiorenal Syndrome
WO2008154238A1 (en) * 2007-06-06 2008-12-18 Siemens Healthcare Diagnostics Inc. Predictive diagnostics for kidney disease

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3569577B2 (ja) * 1995-09-04 2004-09-22 株式会社いかがく 腎・尿路系疾患の鑑別診断用キット
US6498142B1 (en) * 1996-05-06 2002-12-24 Curis, Inc. Morphogen treatment for chronic renal failure
US6228360B1 (en) * 1998-08-19 2001-05-08 Ajinomoto Co., Inc. Antithrombotic agent and humanized anti-von Willebrand factor monoclonal antibody
JP2003030100A (ja) * 2001-07-12 2003-01-31 Fuji Xerox Co Ltd インターネット情報提供システムおよびインターネット情報提供方法
ES2268961B1 (es) * 2005-03-17 2008-03-16 Proyecto De Biomedicina Cima, S.L. Nueva proteina epcr soluble de origen no proteolitico y su uso.
US7833732B2 (en) * 2005-07-21 2010-11-16 The John Hopkins University Acute renal injury
TW200726845A (en) * 2006-01-02 2007-07-16 Nat Defense Medical Ct Biomarker molecular of renal illness and detecting method for the same
US7662578B2 (en) * 2006-04-21 2010-02-16 Children's Hospital Medical Center Method and kit for the early detection of impaired renal status
US20080038269A1 (en) * 2006-05-25 2008-02-14 Mount Sinai Hospital Methods for detecting and treating kidney disease
GB0617429D0 (en) * 2006-09-05 2006-10-18 Electrophoretics Ltd Markers of renal transplant rejection and renal damage

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080254485A1 (en) * 2006-11-14 2008-10-16 Biosite Incorporated Methods And Compositions For Monitoring And Risk Prediction In Cardiorenal Syndrome
WO2008154238A1 (en) * 2007-06-06 2008-12-18 Siemens Healthcare Diagnostics Inc. Predictive diagnostics for kidney disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6013057132; Montagna G, Hofer CG, Torres AM.: 'Impairment of cellular redox status and membrane protein activities in kidneys from rats with ischem' Biochim Biophys Acta. Vol.1407,No.2, 19980814, Page.99-108 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016505860A (ja) * 2013-01-29 2016-02-25 アスチュート メディカル,インコーポレイテッド 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物

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Publication number Publication date
HK1162617A1 (en) 2012-08-31
CN106546752A (zh) 2017-03-29
CN104111336A (zh) 2014-10-22
AU2010210535B2 (en) 2015-12-10
CN102369293A (zh) 2012-03-07
MX2011008323A (es) 2011-09-21
WO2010091231A1 (en) 2010-08-12
JP2016194526A (ja) 2016-11-17
AU2010210535A1 (en) 2011-09-15
BRPI1007917A2 (pt) 2019-09-24
CN102369293B (zh) 2014-05-28
HK1200218A1 (en) 2015-07-31
EP2393937A1 (en) 2011-12-14
US20160123996A1 (en) 2016-05-05
CA2751424A1 (en) 2010-08-12
CN104111336B (zh) 2017-01-18
EP2393937A4 (en) 2012-08-08
JP2015096870A (ja) 2015-05-21
NZ630621A (en) 2016-03-31

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