CN102366558A - Reagent for relieving heat toxin - Google Patents

Abstract

The invention discloses a reagent for relieving heat toxin, which comprises the following components in part by weight: 3-4 parts of coptis, 1-2 parts of ginseng, 3-5 parts of scrophularia, 1-2 parts of schisandra, 2-3 parts of licorice, 2-4 parts of nonglutinous rice, 3-5 parts of pinellia, and 30-40 parts of clear water, and also comprises the following components in part by mass: 3-5 parts of magnolia officinalis and 3-5 parts of white mulberry root-bark. The invention has the advantages that: coptis, ginseng, scrophularia, schisandra, licorice, nonglutinous rice, pinellia and other purely natural plants are added to the reagent for relieving heat toxin.

Description

Separate pyretic toxicity reagent

Technical field

The present invention relates to a kind of beverage, is a kind of pyretic toxicity reagent of separating specifically.

Background technology

Cold symptoms such as the symptom of pyretic toxicity is seen the headache aversion to cold more, and hyperpyrexia is lossless, or antiperspirant is arranged, but heat do not move back, and joint, the whole body is miserable.Simultaneously, the flushed complexion xerostomia is arranged again, thirsty think of drink, it is sleepy, vexed uncomfortable in chest to take off painful abdominal mass, or nausea and vomiting, affection by summer heat affection of dampness performance such as loose stool and diarrhea, this is that summer-heat is held back by cold-damp and caused.Hot summer days in cause summer, gas was hot, steamed on the ground vapour, and the people therein, and is careless slightly, is easy to be disease.The normal human is under the control of maincenter, and heat production is in dynamic equilibrium, about 37 ℃.When the people in when motion. organism metabolism quickens, and heat production increases.Human vas expansion, blood flow quicken, and accelerated breathing etc. are sent to the heat that produces in the body in the body.In sultry classroom, room, public place take place, especially reach in the season examination hall and take place, headache, then body temperature raise rapidly,, flushing even stupor.Mostly the existing heating agent of separating is the pure chemistry composition or adds the part chemical constituent in the majority; Like application number is to be 2002-12-10 02154259.7 applying date; Name is called the patent of invention of " the heatstroke preparation that comprises xylitol "; Its technical scheme is: relate to a kind of heating agent of separating through other medication administration except that oral, it is characterized in that said preparation comprises xylitol, and be a kind ofly to separate heating agent by what the antipyretic and the xylitol of collaborative amount were formed to other more.The invention still further relates to this application of heating agent in pharmaceutical applications of separating, wherein xylitol can be used as the medicine with refrigeration function, for example combines to use with other the medicine of the antipyretic-antalgic group that has or do not have antiinflammatory action.Also relate to its application in infection, virus and bacterial infection that treatment is caused by parasite, and the application in treatment pyretic toxicity, burn, chemical poisoning or any thermoregulation dysfunction.But added anti-inflammatory drugs such as aspirin in its invention scheme, too much absorption said medicine is to healthy unhelpful.

Summary of the invention

The present invention is intended to overcome the defective of above-mentioned prior art, provide a kind of reduce chemical addition agent as far as possible separate pyretic toxicity reagent.

The objective of the invention is to realize through following scheme:

Separate pyretic toxicity reagent; It is characterized in that: comprise Rhizoma Coptidis, Radix Ginseng, Radix Scrophulariae, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Semen oryzae sativae, the Rhizoma Pinelliae, clear water composition; The wherein wt ratio is Rhizoma Coptidis 3-4 part, Radix Ginseng 1-2 part, Radix Scrophulariae 3-5 part, Fructus Schisandrae Chinensis 1-2 part, Radix Glycyrrhizae 2-3 part, Semen oryzae sativae 2-4 part, Rhizoma Pinelliae 3-5 part, clear water 30-40 part.

Said separating in the pyretic toxicity reagent also comprises Cortex Magnoliae Officinalis and Cortex Mori, and its mass fraction is: Cortex Magnoliae Officinalis 3-5 part, Cortex Mori 3-5 part.

Said each the constituent mass umber of pyretic toxicity reagent of separating is: 3 parts of Rhizoma Coptidis, 2 parts of Radix Ginsengs, 3 parts of Radix Scrophulariae, 2 parts of Fructus Schisandrae Chinensis, 2 parts in Radix Glycyrrhizae, 4 parts of Semen oryzae sativaes, 3 parts of the Rhizoma Pinelliaes, 40 parts in clear water, 5 parts of Cortex Magnoliae Officinalis, 3 parts of Cortex Mori.

The invention has the advantages that:

1, pure natural plants such as Rhizoma Coptidis, Radix Ginseng, Radix Scrophulariae, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Semen oryzae sativae, the Rhizoma Pinelliae in separating pyretic toxicity reagent, have been added; Do not add other chemical addition agents; Make the user can not impact other aspects of health because of too much edible chemical addition agent wherein and the discomfort that causes healthy aspect.

2, the present invention has added Cortex Magnoliae Officinalis and Cortex Mori, the expectorant of Cortex Magnoliae Officinalis dampness, and the therapeutic method to keep the adverse QI flowing downwards is removed full, is used for the humidity hysteresis damaging the spleen and stomach, and the gastral cavity painful abdominal mass is vomited and diarrhoea, stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.And Cortex Mori has eliminating pathogen from the lung for relieving asthma, the effect of line water detumescence.

The specific embodiment

Embodiment 1

Separate pyretic toxicity reagent; Comprise Rhizoma Coptidis, Radix Ginseng, Radix Scrophulariae, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Semen oryzae sativae, the Rhizoma Pinelliae, clear water composition, the wherein wt ratio is 3 parts of Rhizoma Coptidis, 2 parts of Radix Ginsengs, 3 parts of Radix Scrophulariae, 2 parts of Fructus Schisandrae Chinensis, 2 parts in Radix Glycyrrhizae, 4 parts of Semen oryzae sativaes, 3 parts of the Rhizoma Pinelliaes, 40 parts in clear water; 5 parts of Cortex Magnoliae Officinalis, 3 parts of Cortex Mori.

The dry rhizome of Coptis deltoidea C.Y.Cheng et Hsiao Coptis deltoidea C. Y. Cheng et Hsiao or Coptis Teeta Wall Coptis teeta Wall..More than three kinds practise to claim " flavor connects ", " refined company ", " Coptis Teeta Wall " respectively.Excavate autumn, removes fibrous root and silt, and drying is hit residual fibrous root.These article are herbaceos perennial, and phyllopodium is hesitated, hard papery, and ovum shape triangle, three totally cleave, central sliver ovum shape rhombus, the pinniform drastic crack, there is sharp sawtooth at the edge, and the adnation sliver does not wait 2 drastic cracks; The long 5-12cm of petiole.Wild or cultivate cool wet the concealment in the thick forest in the mountain valley of height above sea level 1000-1900m.Heat clearing and damp drying is arranged, the effect of eliminating fire and detoxication.Rhizome contains multiple alkaloid; It mainly is berberine; Claim that again berberine (Berberine) is about 5%～8%; Secondly be coptisine (Coptisine), 13-methyl-.psi.-coptisine. (Worenine), palmatine (palmatine; Palmatine), jateorhizine (Jatrorrhizine), Columbamine (Columbamine). still contain obacunone (Obakunone), obakulactone (Obakulactone), magnoflorine (Magnoflorine), ferulic acid (Ferulic acid) etc. leaf contains berberine 1.4%～2.8%. in addition; Also contain various trace elements in the Rhizoma Coptidis. from Coptis deltoidea C.Y.Cheng et Hsiao isolation identification coptisine, berberine, palmatine and jateorhizine. resisting pathogenic microbes effect, antibacterial action staphylococcus aureus, Hemolytic streptococcus, streptococcus pneumoniae, meningococcus, dysentery bacterium, anthrax bacillus etc.Antivirus action suppresses influenza virus, hepatitis B virus etc.Protozoacide effect vitro inhibition ameba, trichomonas vaginitis, trypanosomicide.Influence to cardiovascular system.Arrhythmia, the effective ingredient berberine.Mechanism of action over reach current potential time-histories and effective refractory period.Suppress the sodium channel, the conduction of slowing down, elimination is turned back.Suppress flow of calcium ions.The free radical resisting damage, the protection cell membrane.The hypotensive effect diastolic pressure descends obviously, and pulse pressure difference strengthens.No tachylaxis.Limbs and internal organs are volume gain during blood pressure lowering.The competitive blocking-up of mechanism of action alpha-receptor reduces Peripheral resistance, decreased heart rate.The positive inotropic action heart is excited, myocardial contraction strengthens, and cardiotonic does not receive, and reserpine, propranolol, phentolamine and cut-out are vagal to be influenced.The mechanism of action stops the K+ outflow.Increase Ca2+ concentration in the cell.Suppress the generation of free radical, reduce MDA damage of myocardial cells.Reduce myocardial oxygen consumption.Detoxication antagonism bacteriotoxin, reduction staphylococcus aureus coagulase, hemolysin are tired, and reduce colibacillary virulence.Antiinflammatory, analgesic inhibition kinds of experiments property inflammation, effective ingredient is a berberine, antiinflammatory mechanism discharges relevant with the stimulation corticotropin.Refrigeration function is relevant with the generation that suppresses maincenter PO/AH district neuron cAMP.The anticoagulant mechanism of action suppresses the generation of TXA2 in the platelet.Suppress platelet membrane and discharge arachidonic acid, and influence its metabolism.Suppress stream in the outer calcium.

Embodiment 2

Separate pyretic toxicity reagent; Comprise Rhizoma Coptidis, Radix Ginseng, Radix Scrophulariae, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Semen oryzae sativae, the Rhizoma Pinelliae, clear water composition, the wherein wt ratio is 4 parts of Rhizoma Coptidis, 2 parts of Radix Ginsengs, 4 parts of Radix Scrophulariae, 4 parts of Fructus Schisandrae Chinensis, 3 parts in Radix Glycyrrhizae, 3 parts of Semen oryzae sativaes, 5 parts of the Rhizoma Pinelliaes, 40 parts in clear water; 5 parts of Cortex Magnoliae Officinalis, 5 parts of Cortex Mori.

The Radix Scrophulariae pharmacological action is to the effect of cardiovascular system, and these article infusion, pure immersion and decoct can cause blood pressure drops to multiple animals such as anesthetized dog, cat, rabbits.Po Radix Scrophulariae decoct 2g/kg, every day 2 times, more obvious than healthy dogs to the hypotensive effect of renal hypertension dog.The contained asparagine iv of these article can cause that animal blood pressure descends, the peripheral blood vessel expansion, and heart contractility strengthens, and heart rate is slack-off to be increased with the urine amount.The Radix Scrophulariae ethanol extraction can obviously increase the extrasomatic rabbit heart coronary flow, increases mouse cardiac muscle 86 rubidium intakes, and rabbit experiment property myocardial ischemia due to the pituitrin is had protective effect, can also strengthen the mice hypoxia-bearing capability, and anesthetized cat is had certain hypotensive effect.In addition, Radix Scrophulariae can also increase the rabbit ear perfusion flow that exsomatizes, and rabbit aorta vasospasm due to potassium chloride and the epinephrine is had certain mitigation central inhibitory action, and antibacterial action 50% decoct is used plate dilution method, and staphylococcus aureus is had inhibitory action.The bright method of Radix Scrophulariae leaf has inhibitory action with the flat board method that burrows to bacillus pyocyaneus.Preserved material is used tube dilution method, and 1:160 has inhibitory action to tinea barbae trichobacteria, microsporum canis.To multiple pathogenic and the non-pathogenic fungus is inhibited.Extractum has slight hypoglycemic activity to rabbit.

Embodiment 3

Separate pyretic toxicity reagent; Comprise Rhizoma Coptidis, Radix Ginseng, Radix Scrophulariae, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Semen oryzae sativae, the Rhizoma Pinelliae, clear water composition, the wherein wt ratio is 4 parts of Rhizoma Coptidis, 2 parts of Radix Ginsengs, 4 parts of Radix Scrophulariae, 4 parts of Fructus Schisandrae Chinensis, 3 parts in Radix Glycyrrhizae, 3 parts of Semen oryzae sativaes, 3 parts of the Rhizoma Pinelliaes, 35 parts in clear water; 4 parts of Cortex Magnoliae Officinalis, 3 parts of Cortex Mori.

Fructus Schisandrae Chinensis is perennial fallen leaves liana, belongs to Magnoliaceae, can do medicinally, and plant can supply to view and admire.For magnoliaceae schisandra (Schisandra chinensis (Turcz.) Baill.) is practised title " Radix Schisandrae Bicoloris ", or schisandra chinensis (Schisandra sphenantheraRehd.etWils.) is practised the dry mature fruit of claiming " Fructus Schisandrae Sphenantherae ".Treasure once called: " there is the branch in north and south five tastes the present, and southern product person color is red, and northern product person darkish complexion, people's tonic must use the northern product person good ".It is two kinds that Chinese Pharmacopoeia version in 2000 is recorded Radix Schisandrae Bicoloris and Fructus Schisandrae Sphenantherae respectively.Fructus Schisandrae Chinensis only refers in particular to the dry mature fruit of Radix Schisandrae Bicoloris.And Fructus Schisandrae Sphenantherae refers in particular to the dry mature fruit of schisandra chinensis.Fructus Schisandrae Chinensis can protect human five internal organs-heart, liver, spleen, lung, kidney in Japan and Chinese Pharmacopoeia, and Fructus Schisandrae Chinensis is popular monograph subject matter.Before more than 2,000 years, Royal Palace noble and Chinese medicine master generally adopt the quality goods of keeping fit that this tradition continues to use.Fructus Schisandrae Chinensis, as the term suggests be a kind of fruit with suffering, sweet, sour, bitter, salty five kinds of property of medicine, generally only have one, in the middle of the Chinese crude drug of two kind of flavour of a drug, real genus uniqueness.The fruit of this bittersweet, mutual generation of five phases can be to the Ren body Wu Zang – heart, liver, spleen, lung and kidney performance balanced action.Fructus Schisandrae Chinensis contains rich organic acid, vitamin, flavonoid, phytosterol and the lignan of strong effect reactivation (for example schisandrin, schisandrin B or Fructus Schisandrae Chinensis fat are plain) is arranged; It also is one of minority medical material that has concurrently essence, gas, refreshing three big tonifications, the strong liver of ability QI invigorating, the efficient of promoting the cells exclude refuse, supply more oxygen, construction and uses energy, improving memory and property endurance.In ancient times, Russian hunter must take Fructus Schisandrae Chinensis to keep fit QI invigorating before going on a long journey at every turn and hunting.Fructus Schisandrae Chinensis has outstanding effect, comprising: protect the liver and the liver organization of regenerating, liver is the maincenter detoxifcation organ of human body, is responsible for the filtering noxious substance, in order to avoid human body is damaged.Fructus Schisandrae Chinensis can promote detoxification processes, the liver protecting of liver to avoid poisoning, and can regenerate because of the impaired liver organization of abuse of alcohol, medicine or hepatitis.Fructus Schisandrae Chinensis also can reduce the Zhuan An Mei – alanine transaminase (reducing by 75% in SGPT/ALT-20 days) and first type fetoprotein (AFP-is widely used in biochemical blood test most the to detect hepatocarcinoma) level of continuous rising effectively; Compared with the silymarin that is widely known by the people (taking from Herba Silybi mariani), its effectiveness is safer.Acetaminophen (a kind of analgesic of bringing down a fever commonly used) is enough to reduce glutathion (GSH) level of liver, possibly cause liver damage.Fructus Schisandrae Chinensis can quicken the metabolic rate of acetaminophen and lower the GSH consume, helps the liver protecting.Human test result shows that Fructus Schisandrae Chinensis is especially effective for suffering from the due to illness malicious chronic hepatitis person's (comprising A type, Type B, C type, D type and E type) who is caused.In fact, a clinical experiment report according to China shows that it is having 76% success rate aspect the treatment hepatitis patient, and has no side effect.Fructus Schisandrae Chinensis has the antiinflammation Fructus Schisandrae Chinensis and has antiinflammation, to prevent hepar damnification, activates anabolic process promoting impaired hepatocellular reparation, and can strengthen the activity of DNA (DNA) synthetic and ornithine decarboxylase, the liver cell of regenerating.Carbon tetrachloride (CCl4) is wherein a kind of material that the tool of liver is poisoned.Countless research shows, the toxic action that the strong effect liver-protecting efficacy of Fructus Schisandrae Chinensis can resist CCl4.This shows; Fructus Schisandrae Chinensis avoids aspect the daily toxin infringement very big effect being arranged at the liver protecting, protection and enhancing heart body, and Fructus Schisandrae Chinensis helps histiocytic exchange of oxygen; And in some anoxias and myocardium impaired case, obtained confirmation and can produce protective effect heart tissue.It also gently palmic rate with relieve hypertension.Yin nourishing controlling nocturnal emission with astringent drugs, Fructus Schisandrae Chinensis suitable for men women and children are one of distinguished, the unisex yin nourishing controlling nocturnal emission with astringent drugs of effect tonics, can promote sexual behavior endurance and the excitability of promoting female vulva.It can activate the generation of nitric oxide (NO), and then strengthens male's muscle power and endurance.It is sound to promote intelligence, and Fructus Schisandrae Chinensis can activate nervous system, promote respond, concentrate power and coordinative role, and it is clear to strengthen thinking.Although it has activated effect, there is not caffeine side effect restless.This slight berry also is used to treat the melancholia sometimes, and helps the irritated and forgetful problem of improvement.It is anti-to strengthen physical ability.Fructus Schisandrae Chinensis ability stamina intensifying and strength is also quickened antisecosis.In Russia, be the result of study demonstration of subjects with Plant personnel and child, Fructus Schisandrae Chinensis can be promoted endurance, physical strength reinforcing and minimizing and suffer from disease.Anti-anti-free radical infringement, free radical is to cause the insufficient main cause of atherosclerosis, cancer, coronary heart disease and immunity, also is the arch-criminal who causes ageing process to quicken.The contained lignan of Fructus Schisandrae Chinensis is to imitate antioxidant by force, can suppress free radical, and can increase the level of the Kang Yangization Ji – glutathion in the liver.Delay the aging process, research report shows that Fructus Schisandrae Chinensis often is used as the tonic of aging resistance and QI invigorating, and recent result of study has more been illustrated this principle.Discover that the contained lignan of Fructus Schisandrae Chinensis can strengthen the energy production of adenosine triphyosphate (ATP) or grain line body (cellular energy storehouse), the line body of protection is simultaneously avoided oxidative pressure and is encroached on.Why these effects are enough to explain that Fructus Schisandrae Chinensis can slow down ageing process and delay to occur ageing-related disease,, Alzheimer disease depleted like heart and Parkinson's disease.Nourishing and enhancing kidney function; On the angle of the traditional Chinese medical science, Fructus Schisandrae Chinensis often is used to nourishing kidney and promotes the production of body fluid, and helps treatment night sweat, excessive thirst and pollakiuria problem; And also helpful strong effect adapts to agent aspect treatment urinary incontinence and premature ejaculation; Ability counter pressure and emergency situations Fructus Schisandrae Chinensis are that the most effectively plant adapts to one of agent, can promote intelligence, physical ability and sense organ function, and strengthen the resistance to pressure.In brief, it can help human body to bear the pressure factor such as hot and cold, noise, emotion over loading, so help to promote work performance, stamina intensifying and lessen fatigue.

Claims (3)

1. separate pyretic toxicity reagent; It is characterized in that: comprise Rhizoma Coptidis, Radix Ginseng, Radix Scrophulariae, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Semen oryzae sativae, the Rhizoma Pinelliae, clear water composition; The wherein wt ratio is Rhizoma Coptidis 3-4 part, Radix Ginseng 1-2 part, Radix Scrophulariae 3-5 part, Fructus Schisandrae Chinensis 1-2 part, Radix Glycyrrhizae 2-3 part, Semen oryzae sativae 2-4 part, Rhizoma Pinelliae 3-5 part, clear water 30-40 part.

2. the pyretic toxicity reagent of separating according to claim 1 is characterized in that: said separating in the pyretic toxicity reagent, also comprise Cortex Magnoliae Officinalis and Cortex Mori, and its mass fraction is: Cortex Magnoliae Officinalis 3-5 part, Cortex Mori 3-5 part.

3. the pyretic toxicity reagent of separating according to claim 2; It is characterized in that: said each the constituent mass umber of pyretic toxicity reagent of separating is: 3 parts of Rhizoma Coptidis, 2 parts of Radix Ginsengs, 3 parts of Radix Scrophulariae, 2 parts of Fructus Schisandrae Chinensis, 2 parts in Radix Glycyrrhizae, 4 parts of Semen oryzae sativaes, 3 parts of the Rhizoma Pinelliaes; 40 parts in clear water, 5 parts of Cortex Magnoliae Officinalis, 3 parts of Cortex Mori.