CN102357213A - Method for preparing nasosinusitis particles without cane sugar - Google Patents

Method for preparing nasosinusitis particles without cane sugar Download PDF

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Publication number
CN102357213A
CN102357213A CN2011103230425A CN201110323042A CN102357213A CN 102357213 A CN102357213 A CN 102357213A CN 2011103230425 A CN2011103230425 A CN 2011103230425A CN 201110323042 A CN201110323042 A CN 201110323042A CN 102357213 A CN102357213 A CN 102357213A
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China
Prior art keywords
radix
volatile oil
herba asari
flos
flos magnoliae
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CN2011103230425A
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CN102357213B (en
Inventor
方祎
吴学琴
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NINGXIA GOLD SUN PHARMACEUTICAL CO Ltd
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NINGXIA GOLD SUN PHARMACEUTICAL CO Ltd
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Publication of CN102357213A publication Critical patent/CN102357213A/en
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Abstract

The invention relates to a medicine for curing nasosinusitis, which is prepared from cocklebur fruit, magnolia flower essential oil, radix angelicae, asarum essential oil, honeysuckle, caulis lonicerae, dandelion, liquorice, Platycodon grandiflorum, chrysanthemum, Scutellaria baicalensis, root of common peony, semen coicis and rehmannia; the medicine disclosed by the invention can enter channels, such as lungs, stomachs and the like; all channels are lucid in yang and upwardly go to the nose; the medicines have the functions of eliminating evil, stopping nasal mucus, smoothing nasal obstruction and promoting apertures; the medicine is properly applied to all people suffering from snuffle and runny nose and without smell sense; and the medicine disclosed by the invention is capable of stopping headache and has the advantages of being lower in cost, simple and convenient for manufacture and good in curative effect.

Description

No sucrose sinusitis preparation method of granules
Technical field
The present invention relates to a kind of Chinese herbal medicine, relate in particular to a kind of medicine of treating sinusitis.
Background technology
Sinusitis belongs to a kind of pertinacious disease, is difficult for curing, and is accompanied by the nasal obstruction headache, patient's operate as normal is lived bring very big influence.The method of treatment sinusitis is various both at home and abroad at present, the traditional Chinese medical science, Western medicine drug therapy is arranged, or use operative treatment.Western medicine generally adopts antibiotic, sulfa drugs, nasal drop etc., is easy to generate Drug resistance but go up a type medicine, also is prone to suffer from medicamentous rhinitis in the time of collunarium.And the effect of Chinese traditional treatment does not at present reach gratifying degree yet.Operative treatment adopts puncture to take out dense method usually, brings very big misery to the patient, and easy relapse, and therapeutic effect is not ideal.
Summary of the invention
The objective of the invention is for a kind of oral medicinal herb granule of efficacious therapy sinusitis is provided, its side effect is little, can treat sinusitis effectively.
The present invention is a kind of no sucrose sinusitis granule, and its preparation medicine is:
Fructus Xanthii, Flos Magnoliae volatile oil, the Radix Angelicae Dahuricae, Herba Asari volatile oil, Flos Lonicerae, Caulis Lonicerae, Herba Taraxaci, Radix Glycyrrhizae, Radix Platycodonis, Flos Chrysanthemi, Radix Scutellariae, Radix Paeoniae Rubra, Semen Coicis and Radix Rehmanniae.
Medicine of the present invention can be gone into warps such as lung, stomach, and it is up in nose to draw the clear sun of all warps, eliminating evil tears, the Tong Saili key of ending.All all nasal obstruction watery nasal discharges, good and foul smellsly do not hear, all should use it.The present invention can only have a headache, and expense is lower, makes simple and conveniently, and therapeutic effect is good.
The specific embodiment
The present invention is a kind of no sucrose sinusitis granule, prepares totally 14 kinds of required medicines, and concrete proportioning is during preparation:
Fructus Xanthii 125-140g, Flos Magnoliae 25-40g, Radix Angelicae Dahuricae 95-110g, Herba Asari 25-40g, Flos Lonicerae 70-90g, Caulis Lonicerae 280-300g, Herba Taraxaci 120-140g, Radix Glycyrrhizae 35-50g, Radix Platycodonis 65-80g, Flos Chrysanthemi 60-80g, Radix Scutellariae 65-80g, Radix Paeoniae Rubra 65-80g, Semen Coicis 125-140g, Radix Rehmanniae 95-110g.
Described adjuvant is selected dextrin, starch, microcrystalline Cellulose, calcium bicarbonate, one or more mixing of steviosin for use.
In said medicine, Fructus Xanthii has the effect of diffusing wind dehumidifying, understand things pain-stopping; Flos Magnoliae Anhydroalkannin antiallergic, dispersing wind-cold, a surname's clearing the nasal passage; Radix Angelicae Dahuricae expelling pathogenic wind from the body surface, dispersing cold for relieving pain, sensible, the detumescence and apocenosis of dehumidifying; Herba Asari is returned lung kidney channel, sensible dispersing cold for relieving pain; The Flos Lonicerae heat-clearing and toxic substances removing; The heat clearing away of chrysanthemum powder forimproving wind; The Radix Scutellariae clearing away heat-fire; But Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, complementary collaborative.
Method for preparing of the present invention is:
1. extract the volatile oil of Herba Asari, Flos Magnoliae earlier: obtain the volatile oil 160-240mg of Herba Asari, Flos Magnoliae, subsequent use; The method of extracting volatile oil is: with above-mentioned Herba Asari, Flos Magnoliae moistening, drop in the multi-function extractor, close loam cake and exhaust-valve; Open the receipts fuel tap; Slowly open straight air valve, pressure is no more than 0.02mpa, and interlayer air valve pressure is no more than 0.03mpa; Open cooling water water intaking valve and oil water separator feed liquor valve, close the oil water separator blowoff valve.Close true air valve, use indirect steam, treat to have in the oil water separator volatile oil to occur, collected 80 minutes, reduce steam pressure simultaneously; Or: exsiccant Herba Asari, Flos Magnoliae drop into CO 2In the extraction equipment, airtight, open CO 2Switch, 30-40 ℃ of adjustment temperature, pressure 20-50MPa, extraction, rectification obtain volatile oil;
2. the medicinal residues of Herba Asari, Flos Magnoliae and above-mentioned 12 flavor medicine decocte with water are three times, and collect decoction liquor: filter, concentrate, mass density is 1.10-1.35, and is subsequent use;
3. the processing of adjuvant: a kind of in starch, microcrystalline Cellulose, dextrin, calcium bicarbonate, the steviosin or mix several kinds 80 mesh sieves;
4, mix: adjuvant is mixed the back stir with above-mentioned filtrate, the consumption of adjuvant is the liquid-solid 52-82% that contains thing weight of above-mentioned decoction;
5. drying and granulating: with mixed dry materials, temperature is controlled at 40-60 ℃, and particle drying to moisture is processed granule with machine below 4%;
6. select grain: select grain to the granule that makes with 12 mesh sieves, 70 mesh sieves respectively;
7. total mixing: granule is sprayed into the volatile oil of Herba Asari, Flos Magnoliae, mixed 10-25 minute, airtight, encapsulate.
The present invention has curative effect preferably through clinical experiment.As medicine, its criterion of therapeutical effect can be made as three grades:
(1) cure: the sinusitis symptom all disappears,
(2) take a turn for the better: symptom obviously reduces,
(3) invalid: as to take symptom through many days and lose minimizing.
The present invention is through taking for many people, and its clinical effectiveness is following: (20 days is a course of treatment)
Somewhere treatment patient 20 people through taking no sucrose sinusitis granule, 1-2 course of treatment cure 17 people, and 3 people take a turn for the better.
Somewhere patient 30 people through taking no sucrose sinusitis granule, 1-2 course of treatment cure 22 people, and 8 people take a turn for the better.

Claims (3)

1. no sucrose sinusitis granule, its preparation medicine is:
Fructus Xanthii, Flos Magnoliae volatile oil, the Radix Angelicae Dahuricae, Herba Asari volatile oil, Flos Lonicerae, Caulis Lonicerae, Herba Taraxaci, Radix Glycyrrhizae, Radix Platycodonis, Flos Chrysanthemi, Radix Scutellariae, Radix Paeoniae Rubra, Semen Coicis and Radix Rehmanniae.
2. no sucrose sinusitis granule according to claim 1, the concrete proportioning of its preparation medicine is:
Fructus Xanthii 125-140g, Flos Magnoliae 25-40g, Radix Angelicae Dahuricae 95-11Og, Herba Asari 25-40g, Flos Lonicerae 70-90g, Caulis Lonicerae 280-300g, Herba Taraxaci 120-140g, Radix Glycyrrhizae 35-50g, Radix Platycodonis 65-80g, Flos Chrysanthemi 60-80g, Radix Scutellariae 65-80g, Radix Paeoniae Rubra 65-80g, Semen Coicis 125-140g, Radix Rehmanniae 95-11Og.
3. claim 1, the particulate method for preparing of 2 no sucrose sinusitis are:
1) elder generation extracts the volatile oil of Herba Asari, Flos Magnoliae: obtain the volatile oil 160-240mg of Herba Asari, Flos Magnoliae, and subsequent use; The method of extracting volatile oil is: with above-mentioned Herba Asari, Flos Magnoliae moistening, drop in the multi-function extractor, close loam cake and exhaust-valve; Open the receipts fuel tap; Slowly open straight air valve, pressure is no more than 0.02mpa, and interlayer air valve pressure is no more than 0.03mpa; Open cooling water water intaking valve and oil water separator feed liquor valve, close the oil water separator blowoff valve.Close true air valve, use indirect steam, treat to have in the oil water separator volatile oil to occur, collected 80 minutes, reduce steam pressure simultaneously; Or: exsiccant Herba Asari, Flos Magnoliae drop into CO 2In the extraction equipment, airtight, open CO 2Switch, 30-40 ℃ of adjustment temperature, pressure 20-50MPa, extraction, rectification obtain volatile oil;
2) medicinal residues of Herba Asari, Flos Magnoliae and above-mentioned 12 flavor medicine decocte with water are three times, and collect decoction liquor: filter, concentrate, mass density is 1.10-1.35, and is subsequent use;
3) processing of adjuvant: a kind of in starch, microcrystalline Cellulose, dextrin, calcium bicarbonate, the steviosin or mix several kinds 80 mesh sieves;
4) mix: adjuvant is mixed the back stir with above-mentioned filtrate, the consumption of adjuvant is the liquid-solid 52-82% that contains thing weight of above-mentioned decoction;
5) drying and granulating: with mixed dry materials, temperature is controlled at 40-60 ℃, and particle drying to moisture weight is processed granule with machine below 4%;
6) choosing grain: select grain to the granule that makes with 12 mesh sieves, 70 mesh sieves respectively;
7) total mixing: granule is sprayed into the volatile oil of Herba Asari, Flos Magnoliae, mixed 10-25 minute, airtight, encapsulate.
CN201110323042.5A 2011-10-24 2011-10-24 Method for preparing nasosinusitis particles without cane sugar Active CN102357213B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110090277A (en) * 2019-06-14 2019-08-06 西安博爱制药有限责任公司 A kind of pair of pungent Out of Body of Nasosinusitis Granules and preparation method thereof
CN110101791A (en) * 2019-06-14 2019-08-09 西安博爱制药有限责任公司 A kind of pharyngitis mouth-sucking tablet and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101129472A (en) * 2007-08-23 2008-02-27 王培凤 Medicament for treating chronic rhinitis sinusitis
CN101537141A (en) * 2008-03-21 2009-09-23 北京中泰天和科技有限公司 Pharmaceutical composition for clearing away heat and toxic material, dispelling wind and eliminating swelling and relieving sore throat to be sensible

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101129472A (en) * 2007-08-23 2008-02-27 王培凤 Medicament for treating chronic rhinitis sinusitis
CN101537141A (en) * 2008-03-21 2009-09-23 北京中泰天和科技有限公司 Pharmaceutical composition for clearing away heat and toxic material, dispelling wind and eliminating swelling and relieving sore throat to be sensible

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
唐成定: "辛芳通窍汤治疗慢性鼻窦炎40例", 《河南中医》, vol. 10, no. 28, 31 December 2008 (2008-12-31), pages 57 - 58 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110090277A (en) * 2019-06-14 2019-08-06 西安博爱制药有限责任公司 A kind of pair of pungent Out of Body of Nasosinusitis Granules and preparation method thereof
CN110101791A (en) * 2019-06-14 2019-08-09 西安博爱制药有限责任公司 A kind of pharyngitis mouth-sucking tablet and preparation method thereof

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